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https://www.readbyqxmd.com/read/29342303/biomarkers-for-tobacco-exposures-toxicology-regulation-and-cessation
#1
Andrew W Bergen
No abstract text is available yet for this article.
January 12, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29334961/smoke-alcohol-and-drug-addiction-and-male-fertility
#2
REVIEW
Andrea Sansone, Carla Di Dato, Cristina de Angelis, Davide Menafra, Carlotta Pozza, Rosario Pivonello, Andrea Isidori, Daniele Gianfrilli
In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates and costs. Prevention is the most successful approach to fertility disorders in males and females alike. We performed a literature review on three of the most common unhealthy habits - tobacco, alcohol and drug addiction - and their reported effects on male fertility. Tobacco smoking is remarkably common in most first-world countries; despite a progressive decline in the US, recent reports suggest a prevalence of more than 30% in subjects of reproductive age - a disturbing perspective, given the well-known ill-effects on reproductive and sexual function as well as general health...
January 15, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/29333504/community-based-physical-activity-as-adjunctive-smoking-cessation-treatment-rationale-design-and-baseline-data-for-the-lifestyle-enhancement-program-leap-randomized-controlled-trial
#3
Mark W Vander Weg, Mace Coday, Michelle B Stockton, Barbara McClanahan, George Relyea, Mary C Read, Nancy Wilson, Stephanie Connelly, Phyllis Richey, Karen C Johnson, Kenneth D Ward
Despite advances in behavioral and pharmacological treatment for tobacco use and dependence, quit rates remain suboptimal. Increasing physical activity has shown some promise as a strategy for improving cessation outcomes. However, initial efficacy studies focused on intensive, highly structured exercise programs that may not be applicable to the general population of smokers. We describe the rationale and study design and report baseline participant characteristics from the Lifestyle Enhancement Program (LEAP), a two-group, randomized controlled trial...
March 2018: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29332005/impact-of-a-negative-emotional-antitobacco-mass-media-campaign-on-french-smokers-a-longitudinal-study
#4
Romain Guignard, Karine Gallopel-Morvan, Ute Mons, Karin Hummel, Viêt Nguyen-Thanh
BACKGROUND: Mass media campaigns to encourage smoking cessation have been shown to be effective in a context of comprehensive tobacco control programme. The effectiveness of antismoking ads that evoke negative emotions remains unclear, in particular in countries with high smoking prevalence and among smokers with low perceived susceptibility, low self-efficacy or who are not users of smoking cessation services. OBJECTIVE: To evaluate short-term and long-term effects of a 1-month French national highly emotional media campaign, with a focus on these specific targets...
January 13, 2018: Tobacco Control
https://www.readbyqxmd.com/read/29329763/efficacy-and-safety-of-varenicline-for-smoking-cessation-in-people-living-with-hiv-in-france-anrs-144-inter-activ-a-randomised-controlled-phase-3-clinical-trial
#5
Patrick Mercié, Julie Arsandaux, Christine Katlama, Samuel Ferret, Aurélie Beuscart, Christian Spadone, Claudine Duvivier, Jacques Reynes, Nathalie Wirth, Laetitia Moinot, Antoine Bénard, David Zucman, Xavier Duval, Jean-Michel Molina, Bruno Spire, Catherine Fagard, Geneviève Chêne
BACKGROUND: Tobacco smoking is common in people living with HIV, but high-quality evidence on interventions for smoking cessation is not available in this population. We aimed to assess the efficacy and safety of varenicline with counselling to aid smoking cessation in people living with HIV. METHODS: The ANRS 144 Inter-ACTIV randomised, parallel, double-blind, multicentre, placebo-controlled phase 3 trial was done at 30 clinical hospital sites in France. People living with HIV who had smoked at least ten cigarettes per day for 1 year or longer, were motivated to stop smoking, were not dependent on another psychoactive substance, and had no history of depression or suicide attempt were eligible...
January 9, 2018: Lancet HIV
https://www.readbyqxmd.com/read/29325439/quit-outcomes-and-program-utilization-by-mode-of-entry-among-clients-enrolling-in-a-quitline
#6
Uma S Nair, Ryan C Reikowsky, Betsy C Wertheim, Cynthia A Thomson, Judith S Gordon
PURPOSE: To investigate how mode of entry into a quitline influences program utilization and quit outcomes among clients seeking cessation services. DESIGN: This is a retrospective analysis of clients receiving quitline services from January 2011 to June 2016. SETTING: The study was conducted at the Arizona Smokers' Helpline. PARTICIPANTS: Enrolled clients completed a 7-month follow-up (N = 18 650). MEASURES: The independent variable was referral mode of entry (ie, proactive, passive, and self-referral)...
January 1, 2018: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29325111/risk-of-coronary-heart-disease-among-smokeless-tobacco-users-results-of-systematic-review-and-meta-analysis-of-global-data
#7
Ruchika Gupta, Sanjay Gupta, Shashi Sharma, Dhirendra N Sinha, Ravi Mehrotra
Background: Use of smokeless tobacco (SLT) products has been linked to multiple adverse effects, especially precancer and cancer of oral cavity. However, the association of SLT use with risk of coronary heart disease (CHD) is shrouded with controversy due to conflicting results in the literature. The present meta-analysis aimed to evaluate the risk of CHD among adult ever-users of SLT products along with subgroup analysis. Methods: The analysis included studies retrieved from a systematic literature search for published articles assessing risk of CHD with SLT use...
January 9, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29324248/varenicline-for-tobacco-dependence-treatment-in-alcohol-dependent-smokers-a-randomized-controlled-trial
#8
Ryan T Hurt, Jon O Ebbert, Ivana T Croghan, Darrell R Schroeder, Richard D Hurt, J Taylor Hays
BACKGROUND: Tobacco use is prevalent among persons with alcohol abuse and dependence. Varenicline has been shown to be the most effective pharmacotherapy for smoking cessation and may decrease alcohol consumption. The purpose of this study was to evaluate the efficacy of 12 weeks of varenicline for increasing smoking abstinence rates in smokers with alcohol abuse or dependence. METHODS: Participants were eligible for enrollment if they were 18 years or older, smoked 10 or more cigarettes per day for at least 6 months, had current alcohol abuse or dependence, and were interested in quitting smoking...
January 2, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29321008/effects-of-a-culturally-specific-tobacco-cessation-intervention-among-african-american-quitline-enrollees-a-randomized-controlled-trial
#9
Monica Webb Hooper, Kelly Carpenter, Michael Payne, Ken Resnicow
BACKGROUND: African Americans suffer disproportionately from tobacco-related illness and have more difficulty quitting smoking than other racial/ethnic groups. Previous research indicates that African American treatment-seekers are high utilizers of tobacco quitlines, yet cessation rates via quitlines are lower relative to whites. The goal of the present study is to test the effectiveness of adding a culturally specific, video-based, adjunct to standard quitline care. It is hypothesized that the integration of an evidence-based intervention (Pathways to Freedom: Leading the Way to a Smoke-Free Community©; PTF) into quitline services will increase cessation and treatment engagement compared to control conditions, and that effects will be moderated by sociocultural factors (e...
January 10, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29313652/lung-cancer-smoking-cessation
#10
Kelly M Latimer
Smoking cessation for patients who smoke should be a top priority for physicians. Nicotine dependence should be considered a chronic disease, with the expectation that relapse is normal. The US Preventive Services Task Force (USPSTF) recommends that physicians screen all adults for tobacco use, advise them to stop using tobacco, and provide behavioral interventions and Food and Drug Administration-approved pharmacotherapy for cessation to adults who use tobacco. It also recommends use of the 5 As (ie, Ask, Advise, Assess, Assist, Arrange) in discussing tobacco use with patients...
January 2018: FP Essentials
https://www.readbyqxmd.com/read/29313113/epidemiology-and-contemporary-management-of-abdominal-aortic-aneurysms
#11
Brant W Ullery, Richard L Hallett, Dominik Fleischmann
Abdominal aortic aneurysm (AAA) is most commonly defined as a maximal diameter of the abdominal aorta in excess of 3 cm in either anterior-posterior or transverse planes or, alternatively, as a focal dilation ≥ 1.5 times the diameter of the normal adjacent arterial segment. Risk factors for the development of AAA include age > 60, tobacco use, male gender, Caucasian race, and family history of AAA. Aneurysm growth and rupture risk appear to be associated with persistent tobacco use, female gender, and chronic pulmonary disease...
January 9, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29309599/feasibility-of-a-text-based-smoking-cessation-intervention-in-rural-older-adults
#12
D Noonan, S Silva, J Njuru, T Bishop, L J Fish, L A Simmons, S H Choi, K I Pollak
Text-based interventions are effective for smoking cessation, but have not been tested in rural older adults. The purpose of this study was to compare the feasibility, acceptability and preliminary efficacy of a text-based Scheduled Gradual Reduction (SGR) program to a non-SGR text messaging support condition among rural older adults. Adults over 60 years were randomized to either: (i) the SGR program (n = 20), a text-based program to reduce smoking over 4-weeks plus text-based support messages; or (ii) control (n = 20), receipt of text-based support messages only...
January 4, 2018: Health Education Research
https://www.readbyqxmd.com/read/29307500/preparing-the-way-exploiting-genomic-medicine-to-stop-smoking
#13
REVIEW
Laura J Bierut, Rachel F Tyndale
Clinical medicine of the future is poised to use an individual's genomic data to predict disease risk and guide clinical care. The treatment of cigarette smoking and tobacco use disorder represents a prime area for genomics implementation. The genes CHRNA5 and CYP2A6 are strong genomic contributors that alter the risk of heaviness of smoking, tobacco use disorder, and smoking-related diseases in humans. These biomarkers have proven analytical and clinical validity, and evidence for their clinical utility continues to grow...
January 4, 2018: Trends in Molecular Medicine
https://www.readbyqxmd.com/read/29306721/comparative-risk-assessment-and-cessation-information-seeking-among-smokeless-tobacco-users
#14
Jungmi Jun, Xiaoli Nan
INTRODUCTION: This research examined (1) smokeless tobacco users' comparative optimism in assessing the health and addiction risks of their own product in comparison with cigarettes, and (2) the effects of comparative optimism on cessation information-seeking. METHODS: A nationally-representative sample from the 2015 Health Information National Trends Survey (HINTS)-FDA was employed. RESULTS: The analyses revealed the presence of comparative optimism in assessing both health and addiction risks among smokeless tobacco users...
December 28, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29303995/local-acetaldehyde-an-essential-role-in-alcohol-related-upper-gastrointestinal-tract-carcinogenesis
#15
REVIEW
Mikko T Nieminen, Mikko Salaspuro
The resident microbiome plays a key role in exposure of the upper gastrointestinal (GI) tract mucosa to acetaldehyde (ACH), a carcinogenic metabolite of ethanol. Poor oral health is a significant risk factor for oral and esophageal carcinogenesis and is characterized by a dysbiotic microbiome. Dysbiosis leads to increased growth of opportunistic pathogens (such as Candida yeasts) and may cause an up to 100% increase in the local ACH production, which is further modified by organ-specific expression and gene polymorphisms of ethanol-metabolizing and ACH-metabolizing enzymes...
January 5, 2018: Cancers
https://www.readbyqxmd.com/read/29303396/mental-health-correlates-of-cigarette-use-in-lgbt-individuals-in-the-southeastern-united-states
#16
Christopher F Drescher, Eliot J Lopez, James A Griffin, Thomas M Toomey, Elizabeth D Eldridge, Lara M Stepleman
BACKGROUND: Smoking prevalence for lesbian, gay, bisexual, and transgender (LGBT) individuals is higher than for heterosexual, cisgender individuals. Elevated smoking rates have been linked to psychiatric comorbidities, substance use, poverty, low education levels, and stress. OBJECTIVES: This study examined mental health (MH) correlates of cigarette use in LGBT individuals residing in a metropolitan area in the southeastern United States. METHODS: Participants were 335 individuals from an LGBT health needs assessment (mean age 34...
January 5, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29302224/tobacco-use-disorder-and-treatment-new-challenges-and-opportunities
#17
Douglas Ziedonis, Smita Das, Celine Larkin
Tobacco use remains a global problem, and options for consumers have increased with the development and marketing of e-cigarettes and other new nicotine and tobacco products, such as "heat-not-burn" tobacco and dissolvable tobacco. The increased access to these new products is juxtaposed with expanding public health and clinical intervention options, including mobile technologies and social media. The persistent high rate of tobacco-use disorders among those with psychiatric disorders has gathered increased global attention, including successful approaches to individual treatment and organizational-level interventions...
September 2017: Dialogues in Clinical Neuroscience
https://www.readbyqxmd.com/read/29301614/metabotropic-glutamate-receptors-2-and-3-as-targets-for-treating-nicotine-addiction
#18
REVIEW
Alan J Cross, Robert Anthenelli, Xia Li
Tobacco smoking, driven by the addictive properties of nicotine, continues to be a worldwide health problem. Based on the well-established role of glutamatergic neurotransmission in drug addiction, novel medication development strategies seek to halt nicotine consumption and prevent relapse to tobacco smoking by modulating glutamate transmission. The presynaptic inhibitory metabotropic glutamate receptors 2 and 3 (mGluR2/3) are key autoreceptors on glutamatergic terminals that maintain glutamate homeostasis...
November 21, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29301518/young-australian-women-s-accounts-of-smoking-and-quitting-a-qualitative-study-using-visual-methods
#19
Zoi Triandafilidis, Jane M Ussher, Janette Perz, Kate Huppatz
BACKGROUND: Although the overall rate of smoking in Australia continues to decline, the rate of decline has begun to slow. Rates of smoking among young women in Australia have been a particular concern, which has led to the development of targeted public health campaigns. Poststructuralist theory has successfully been used in research to explore the way in which young women experience smoking. However, there is an absence of poststructuralist analysis of young women's experiences of quitting...
January 5, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29300994/sexual-orientation-discrimination-and-tobacco-use-disparities-in-the-united-states
#20
Sean Esteban McCabe, Tonda L Hughes, Alicia K Matthews, Joseph G L Lee, Brady T West, Carol J Boyd, Cynthia Arslanian-Engoren
Introduction: Differences in tobacco/nicotine use by sexual orientation are well documented. Development of interventions requires attention to the etiology of these differences. This study examined associations among sexual orientation discrimination, cigarette smoking, any tobacco/nicotine use, and DSM-5 tobacco use disorder (TUD) in the U.S. Methods: We used data from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions based on in-person interviews with a nationally representative sample of non-institutionalized U...
December 30, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
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