Sigrun Hope, Alexey A Shadrin, Aihua Lin, Shahram Bahrami, Linn Rødevand, Oleksandr Frei, Saira J Hübenette, Weiqiu Cheng, Guy Hindley, Heidi Nag, Line Ulstein, Magdalena Efrim-Budisteanu, Kevin O'Connell, Anders M Dale, Srdjan Djurovic, Terje Nærland, Ole A Andreassen
Autism spectrum disorder (ASD) is a highly heritable condition with a large variation in cognitive function. Here we investigated the shared genetic architecture between cognitive traits (intelligence (INT) and educational attainment (EDU)), and risk loci jointly associated with ASD and the cognitive traits. We analyzed data from genome-wide association studies (GWAS) of INT (n = 269,867), EDU (n = 766,345) and ASD (cases n = 18,381, controls n = 27,969)...
September 14, 2023: Translational Psychiatry