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Yuyang Liu, Zhaoliang Li, Mao Pan
There are many heavy oil reservoirs in offshore oilfields in China. Steam and multiple thermal fluid stimulation technologies are of increasing interest and have been applied to an increasing number of projects. During the stimulation or displacement of heavy oil reservoirs during thermal recovery, several factors, such as reservoir heterogeneity, are prone to cause channeling phenomena and affect the thermal recovery effect of steam stimulation. According to the unique requirements for the stimulation of multiple thermal fluids for offshore heavy oil, this study used transmission, blocking and relieving, heat resistance and a comprehensive evaluation of parallel sand tube experiments to conduct a screening evaluation of plugging systems for the stimulation of multiple thermal fluids, screen out a commonly used plugging agent in the current stage and propose corresponding guidance for the selection basis...
2018: PloS One
Tomaž Šolc, Mihael Mohorčič, Carolina Fortuna
Lack of unallocated spectrum and increasing demand for bandwidth in wireless networks is forcing new devices and technologies to share frequency bands. Spectrum sensing is a key enabler for frequency sharing and there is a large body of existing work on signal detection methods. However a unified methodology that would be suitable for objective comparison of detection methods based on experimental evaluations is missing. In this paper we propose such a methodology comprised of seven steps that can be applied to evaluate methods in simulation or practical experiments...
2018: PloS One
Ninja Ritter Klejnstrup, Julie Buhl-Wiggers, Sam Jones, John Rand
Malaria is a major cause of morbidity and mortality in sub-Saharan Africa. It is also a dynamic contributor to poverty through its effects on children's cognitive development. This paper examines the degree to which malaria in early childhood impacts on educational achievement in later childhood. The substantial decline in malaria in the region over recent years allows an assessment of its impact to be made. Focusing on Tanzania, we combine data from the Malaria Atlas Project and the 2010-2014 Uwezo household surveys (N = 246,325)...
2018: PloS One
Leslie A Sadownik, Paul J Yong, Kelly B Smith
OBJECTIVES OF THE STUDY: To systematically evaluate the literature regarding vulvodynia treatment outcome measures. METHODS: A systematic literature search on OVID, PubMed, and PsycINFO databases was conducted from inception until May 2016. Studies were included/excluded based on prespecified criteria. Reported outcome measures were organized into 6 core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT): pain; physical functioning, emotional functioning, participant ratings of global improvement and satisfaction with treatment, symptoms and adverse events, and participant disposition...
July 2018: Journal of Lower Genital Tract Disease
Charuta N Joshi, Kevin E Chapman, Joshua J Bear, Scott B Wilson, Diana J Walleigh, Mark L Scheuer
PURPOSE: Our objective was to use semiautomatic methods for calculating the spike-wave index (SWI) in electrical status epilepticus in slow-wave sleep (ESES) and to determine whether this calculation is noninferior to human experts (HEs). METHODS: Each HE marked identical 300-second epochs for all spikes and calculated the SWI in sleep EEGs of patients diagnosed with ESES. Persyst 13 was used to mark spikes (high sensitivity setting) in the same 300-second epochs marked by HEs...
June 21, 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
JiaDe Yu, Amber Reck Atwater, Bruce Brod, Jennifer K Chen, Sarah S Chisolm, David E Cohen, Salma de la Feld, Anthony A Gaspari, Kari Lyn Martin, Marjorie Montanez-Wiscovich, Michael Sheehan, Nanette Silverberg, Aida Lugo-Somolinos, Binod K Thakur, Kalman Watsky, Sharon E Jacob
BACKGROUND: Allergic contact dermatitis is a challenging diagnostic problem in children. Although epicutaneous patch testing is the diagnostic standard for confirmation of contact sensitization, it is less used in children by dermatologists treating children, pediatric dermatologists, and pediatricians, when compared with adult practitioners. OBJECTIVE: The aim of the study was to create and evaluate standardization of a pediatric patch test series for children older than 6 years...
June 21, 2018: Dermatitis
Liqiu Zhang, Hee-Jeong Jang, Sung Jae Yoo, Sanghyun Cho, Ji Hye Won, Lichun Liu, Sungho Park
Site-selective synthesis of nanostructures is an important topic in the nanoscience community. Normally, the difference between seeds and deposition atoms in terms of crystallinity triggers the deposition atoms to grow initially at the specific site of nucleation. It is more challenging to control the deposition site of atoms that have the same composition as the seeds because the atoms tend to grow epitaxially, covering the whole surface of the seed nanoparticles. Gold (Au) nano-octahedrons used as seeds in this study possess obvious hierarchical surface energies depending on whether they are at vertices, edges, or terraces...
June 22, 2018: Nanotechnology
Michael Stiehm, Carolin Wüstenhagen, Stefan Siewert, Hüseyin Ince, Niels Grabow, Klaus-Peter Schmitz
Bioresorbable scaffolds (BRS) promise to be the treatment of choice for stenosed coronary vessels. But higher thrombosis risk found in current clinical studies limits the expectations. Three hemodynamic metrics are introduced to evaluate the thrombosis risk of coronary stents/scaffolds using transient computational fluid dynamics (CFD). The principal phenomena are platelet activation and effective diffusion (platelet shear number, PSN), convective platelet transport (platelet convection number, PCN) and platelet aggregation (platelet aggregation number, PAN) were taken into consideration...
June 22, 2018: Biomedizinische Technik. Biomedical Engineering
Yang Bai, Lidia Casas, Hans Scheers, Bram G Janssen, Benoit Nemery, Tim S Nawrot
BACKGROUND: Mitochondria are sensitive to air pollutants due to their lack of repair capacity. Changes in mitochondrial DNA copy number (mtDNAcn) or content is a proxy of mitochondrial damage and has been associated with recent exposure to traffic-derived air pollutants, nitrogen dioxide (NO2 ) and black carbon (BC). Inhaled BC can be phagocytosed by airway macrophages (AMs), and its amount in AM reflects personal exposure to traffic-related air pollution. OBJECTIVES: The present study investigated the relation between the internal marker AM BC and ambient NO2 concentration and examined the associations of mtDNAcn with NO2 and AM BC...
June 19, 2018: Environment International
Meng Ding, Yumeng Zhang, Xude Wang, Yuqing Zhao
Our previous study suggests a well-defined pharmacological activity of 20(R)-25-methoxyl-dammarane-3β,12β,20-triol (AD-1) and its metabolite 20(R)-dammarane-3β,12β,20,25-tetrol (AD-2). The current study aims to investigate the gender-related differences in pharmacokinetics, tissue distribution, and excretion of AD-1 and its metabolite in both male and female rats. A sensitive and rapid ultra-performance liquid chromatography tandem mass spectrometric (UPLC-MS/MS) method was developed for the simultaneous determination of AD-1 and AD-2 levels in plasma, various tissues, bile, urine, and feces...
June 7, 2018: Journal of Pharmaceutical and Biomedical Analysis
Bahareh Babamiri, Abdollah Salimi, Rahman Hallaj
Development of simple, sensitive and specific method for human immunodeficiency virus (HIV) assays are urgently demand. In this study, we developed a novel molecularly imprinted polymer (MIP) electrochemiluminescence (MIP-ECL) sensor for the highly sensitive and selective HIV-1 gene detection using Europium sulfide nanocrystals (EsNCs) as signal producing compound. Here, the HIV aptamer as the template and o-phenylenediamine as the functional monomer, were electropolymerized directly on the surface of ITO electrode...
June 4, 2018: Biosensors & Bioelectronics
Behrouz Golichenari, Rahim Nosrati, Aref Farokhi-Fard, Khalil Abnous, Farzam Vaziri, Javad Behravan
Tuberculosis is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb) complex. According to WHO reports, 53 million TB patients died from 2000 to 2016. Therefore, early diagnosis of the disease is of great importance for global health care programs. The restrictions of traditional methods have encouraged the development of innovative methods for rapid, reliable, and cost-effective diagnosis of tuberculosis. In recent years, aptamer-based biosensors or aptasensors have drawn great attention to sensitive and accessible detection of tuberculosis...
June 11, 2018: Biosensors & Bioelectronics
Madeleine Asklöf, Preben Kjølhede, Ninnie Borendal Wodlin, Lena Nilsson
The aim of this descriptive review is to summarise the current knowledge of non-invasive bioelectrical impedance analysis (BIA) used with gynaecological surgical patients in regard to postoperative development of lymphoedema and determination of perioperative fluid balance, and as a prognostic factor in cancer mortality and a predictor of postoperative complications. The databases PubMed, MEDLINE, Scopus Web of Science, the Cochrane Library, and reference lists of selected articles were searched for relevant articles published during the period January 2008-April 2018...
June 18, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Yue Yi, Beizhen Xie, Ting Zhao, Hong Liu
Microbial fuel cell based biosensors (MFC-biosensors) utilize anode biofilms as biological recognition elements to monitor biochemical oxygen demand (BOD) and biotoxicity. However, the relatively poor sensitivity constrains the application of MFC-biosensors. To address this limitation, this study provided a systematic comparison of sensitivity between the MFC-biosensors constructed with two inocula. Higher biomass density and viability were both observed in the anode biofilm of the mixed culture MFC, which resulted in better sensitivity for BOD assessment...
June 13, 2018: Bioresource Technology
Murad Helaleh, Ilhame Diboun, Nada Al-Tamimi, Haya Al-Sulaiti, Mohamed Al-Emadi, Aishah Madani, Nayef A Mazloum, Aishah Latiff, Mohamed A Elrayess
BACKGROUND: Polybrominated diphenyl ethers (PBDEs), a widely utilized class of flame retardants in various commercial products, represent a prominent source of environmental contaminants. PBDEs tend to accumulate in adipose tissue, potentially altering the function of this endocrine organ and increasing risk of insulin resistance. The aim of this study was to compare levels of PBDEs in adipose tissues from two metabolically distinct obese groups; the insulin sensitive (IS) and the insulin resistant (IR)...
June 18, 2018: Chemosphere
Noha N Atia, Marwa F B Ali
A rapid, highly sensitive and roubst spectrofluorimetric method was developed for trace analysis of silymarin (SLM) in active pharmaceutical ingredient (API), pharmaceutical preparations and human plasma. The proposed method is based on reaction of SLM with a novel reagent; 3-amino-5-pyridin-3-yl-1,2,4-triazole (3-APT); in the presence of 0.04 M sodium hydroxide. The formed fluorescent product was formed within 5 min and was measured at 504 nm after excitation at 390 nm. All reaction parameters were optimized and the proposed method was validated according to ICH guidelines...
June 12, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Douglas S Franciscato, Tiago A Matias, Jorge Shinohara, Josué M Gonçalves, Narcimário P Coelho, Cleverton S Fernandes, Ernani A Basso, Helena S Nakatani, Koiti Araki, Henrique E Toma, Vagner R de Souza
The Raman spectral profile of p-methylcarbohydrazonethioamide (MCHT) is completely changed due to strong SERS effects upon bonding onto gold nanoparticles surface, but some vibrational modes are further enhanced in the presence of Hg(II) ions. The lack of SERS response for most common metal ions indicates that the coordinating groups are interacting with the gold nanoparticles surface and not available for binding metal ions in solution, except for mercury ions. The selective enhancement of some vibrational modes is consistent with significant conformational changes upon binding of Hg(II) ion onto the AuNP@MCHT hybrid, as confirmed by TEM/EDS measurements, demonstrating its potentiality as a highly selective and sensitive SERS substrate...
June 14, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Lukas Kain, Orestis G Andriotis, Peter Gruber, Martin Frank, Marica Markovic, David Grech, Vedran Nedelkovski, Martin Stolz, Aleksandr Ovsianikov, Philipp J Thurner
Mechanical assessment of biological materials and tissue-engineered scaffolds is increasingly focusing at lower length scale levels. Amongst other techniques, atomic force microscopy (AFM) has gained popularity as an instrument to interrogate material properties, such as the indentation modulus, at the microscale via cantilever-based indentation tests equipped with colloidal probes. Current analysis approaches of the indentation modulus from such tests require the size and shape of the colloidal probe as well as the spring constant of the cantilever...
May 17, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Franz W R Hippler, Dirceu Mattos-Jr, Rodrigo M Boaretto, Lorraine E Williams
Nitrate uptake by plants is mediated by specific transport proteins in roots (NRTs), which are also dependent on the activity of proton pumps that energize the reaction. Nitrogen (N) metabolism in plants is sensitive to copper (Cu) toxicity conditions. To understand how Cu affects the uptake and assimilation processes, this study assesses the inhibitory effects of elevated Cu levels on the expression of genes related to N absorption, transport and assimilation in roots of Arabidopsis. Plants were grown hydroponically for 45 days, being exposed to a range of Cu concentrations in the last 72 h or alternatively exposed to 5...
June 14, 2018: Journal of Plant Physiology
Zaid Ulhassan, Skhawat Ali, Rafaqat A Gill, Theodore M Mwamba, Muhammad Abid, Lan Li, Na Zhang, Weijun Zhou
Selenium (Se) is an essential micro-element for human and animals. In higher plants, Se essentiality or phyto-toxicity is less explored. Therefore, we aimed to examine the effects of Se (0, 25, 50, and 100 µM) as sodium selenite on the physio-chemical, cell ultra-structural and genomic alterations in hydroponically grown seedlings of four cultivars of B. napus (cvs. Zheda 619, Zheda 622, ZS 758, and ZY 50). Results showed that excessive (100 µM) Se (IV) exhibited significant reduction in plant growth parameters, declined pigment contents, lower water-soluble protein levels, and overproduction of H2 O2 and MDA contents...
June 19, 2018: Ecotoxicology and Environmental Safety
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