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Zhiming Ma, Jianxia Jiang, Ziwei Hu, Tianqi Lyu, Yang Yang, Jingjing Jiang, Jiashu Cao
We identified and cloned the two precursors of miR158 and its target gene in Brassica campestris ssp. chinensis, which both had high relative expression in the inflorescences. Further study revealed that over-expression of miR158 caused reduced pollen varbility, which was caused by the degradation of pollen contents from the binucleate microspore stage. These results first suggest the role of miR158 in pollen development of Brassica campestris ssp. chinensis. MicroRNAs (miRNAs) play crucial roles in many important growth and development processes both in plants and animals by regulating the expression of their target genes via mRNA cleavage or translational repression...
December 1, 2016: Plant Molecular Biology
Ryan E R Reid, Jessica A Insogna, Tamara E Carver, Andrea M Comptour, Nicole A Bewski, Cristina Sciortino, Ross E Andersen
OBJECTIVES: Inexpensive activity monitors have recently gained popularity with the general public. Researchers have evaluated these consumer-based monitors in laboratory-conditions. Given the current wide-spread consumer use of these devices, it is important to ensure users are attaining accurate information compared to previously validated measures. This study investigates the accuracy of Fitbit One and Flex activity monitors in measuring steps, sedentary time, and time spent in light, moderate, and vigorous intensity activities with ActiGraph GT3X+ with female adults in free-living conditions...
November 16, 2016: Journal of Science and Medicine in Sport
Stefano Soldano, Carmen Pizzorni, Sabrina Paolino, Amelia Chiara Trombetta, Paola Montagna, Renata Brizzolara, Barbara Ruaro, Alberto Sulli, Maurizio Cutolo
BACKGROUND: Alternatively activated (M2) macrophages are phenotypically characterized by the expression of specific markers, mainly macrophage scavenger receptors (CD204 and CD163) and mannose receptor-1 (CD206), and participate in the fibrotic process by over-producing pro-fibrotic molecules, such as transforming growth factor-beta1 (TGFbeta1) and metalloproteinase (MMP)-9. Endothelin-1 (ET-1) is implicated in the fibrotic process, exerting its pro-fibrotic effects through the interaction with its receptors (ETA and ETB)...
2016: PloS One
C E Coltman, J R Steele, D E McGhee
BACKGROUND/PURPOSE: The skin overlying a woman's breast acts as an anatomical support structure to the breast. Although aging is known to affect the thickness and elasticity of human skin, limited research has examined age-related changes to skin covering the breast or related these changes to breast support requirements. The purpose of this study was to determine the effect of age on female breast skin thickness and elasticity. METHODS: The left breast of 339 women (18-84 years), classified into four age groups (18-24 years, 25-44 years, 45-64 years, and 65 + years), was divided into four quadrants...
November 1, 2016: Skin Research and Technology
Ana Carolina Diniz Matos, Júlio César Câmara Rosa, Kyriaki Nomikou, Lorena Lima Barbosa Guimarães, Érica Azevedo Costa, Maria Isabel Maldonado Coelho Guedes, David Driemeier, Zélia Inês Portela Lobato, Peter Paul Clement Mertens
The complete genome sequence of Bluetongue virus (BTV) serotype 17 strain 17/BRA/2014/73, isolated from a sheep in Brazil in 2014, is reported here. All segments clustered with western topotype strains and indicated reassortment events with other BTV from the Americas. The strain 17/BRA/2014/73 represents a novel reference strain for BTV-17 from South America.
October 27, 2016: Genome Announcements
Éverton Luís Pereira, Livia Barbosa
This article derives from a study conducted on the validation of the Brazilian Functionality Index (IF-BrA) applied to the granting of retirement benefits to disabled persons. The retirement of persons with disabilities is regulated by Complementary Law 142 of May 8, 2013. The aim is to discuss how the individuals involved in application of the instrument perceive the concept of disability and the possible implications for ensuring the right to retirement. Eleven agencies of the National Social Security Institute (INSS) were visited and 16 physicians, 16 social workers and 40 persons with disabilities were interviewed...
October 2016: Ciência & Saúde Coletiva
Kana Takahashi, Madoka Morota, Yoshikazu Kagami, Hiroyuki Okamoto, Shuhei Sekii, Koji Inaba, Naoya Murakami, Hiroshi Igaki, Yoshinori Ito, Takashi Uno, Jun Itami
BACKGROUND: This prospective study aimed to compare dose volume histograms (DVH) of the breasts and organs at risk (OARs) of whole breast radiotherapy in the supine and prone positions, and frequency and severity of acute and late toxicities were analyzed. METHODS: Early-stage breast cancer patients with large breasts (Japanese bra size C or larger, or the widest measurements of the bust ≥ 95 cm) undergoing partial mastectomy participated in this study. CT-based treatment plans were made in each position, and various dosimetric parameters for the breast and OARs were calculated to compare the supine and prone radiotherapy plans...
September 29, 2016: BMC Cancer
Michio Yoshida, Eriko Kajikawa, Daisuke Yamamoto, Daisuke Kurokawa, Shigenobu Yonemura, Kensaku Kobayashi, Hiroshi Kiyonari, Shinichi Aizawa
BACKGROUND: Previous comparative studies suggest that the requirement for Nodal in epiblast and hypoblast development is unique to mammalians. Expression of anterior visceral endoderm (AVE) genes in the visceral endoderm and of their orthologs in the hypoblast may be unique to mammalians and avians, and is absent in the reptilian hypoblast. Axis formation in reptiles is signaled by the formation of the posterior marginal epiblast (PME), which expresses a series of primitive streak genes...
December 2016: Developmental Dynamics: An Official Publication of the American Association of Anatomists
Camila Fernandes Pollo Maranzatto, Hélio Amante Miot, Luciane Donida Bartoli Miot, Silmara Meneguin
BACKGROUND: Although asymptomatic, melasma inflicts significant impact on quality of life. MELASQoL is the main instrument used to assess quality of life associated with melasma, it has been validated in several languages, but its latent dimensional structure and psychometric properties haven´t been fully explored. OBJECTIVES: To evaluate psychometric characteristics, information and dimensional structure of the Brazilian version of MELASQoL. METHODS: Survey with patients with facial melasma through socio-demographic questionnaire, DLQI-BRA, MASI and MELASQoL-BP, exploratory and confirmatory factor analysis, internal consistency of MELASQoL and latent dimensions (Cronbach's alpha)...
July 2016: Anais Brasileiros de Dermatologia
(no author information available yet)
While 40% of women feel breast pain while riding, fewer than 20% wear a sports bra.
August 31, 2016: Nursing Standard
Zhenggang Zhang, Michael Chopp
Stroke activates neural stem cells in the ventricular-subventricular zone (V/SVZ) of the lateral ventricle, which increases neuroblasts and oligodendrocyte progenitor cells (OPCs). Within the ischemic brain, neural stem cells, neuroblasts and OPCs appear to actively communicate with cerebral endothelial cells and other brain parenchymal cells to mediate ischemic brain repair; however, stroke-induced neurogenesis unlikely plays any significant roles in neuronal replacement. In this mini-review, we will discuss recent findings how intercellular communications between stroke-induced neurogenesis and oligodendrogenesis and brain parenchymal cells could potentially facilitate brain repair processes...
September 2016: Journal of Stroke
Jenny Burbage, Lorna Cameron
For female horse riders, breast pain, bra issues and breast size may be important concerns which have yet to be considered. This study aimed to establish the prevalence of breast pain and bra issues in female horse riders and explores the impact of breast size on breast pain and bra issues. A 6-part, 32 question online survey was completed by 1324 females who participated in horse riding activities. Descriptive and chi-squared (χ(2)) analyses were utilised; data for 1265 participants were included in the final analysis...
July 25, 2016: Journal of Sports Sciences
Elthon G Ferreira, Maria da Conceição M Torres, Alison B da Silva, Larissa L F Colares, Karine Pires, Tito M C Lotufo, Edilberto R Silveira, Otília D L Pessoa, Leticia V Costa-Lotufo, Paula C Jimenez
Saint Peter and Saint Paul's Archipelago is a collection of 15 islets and rocks remotely located in the equatorial Atlantic Ocean. In this particular site, the present project intended to assess the biodiversity and biotechnological potential of bacteria from the actinomycete group. This study presents the first results of this assessment. From 21 sediment samples, 268 strains were isolated and codified as BRA followed by three numbers. Of those, 94 strains were grown in liquid media and submitted to chemical extractions with AcOEt (A), BuOH (B), and MeOH (M)...
September 2016: Chemistry & Biodiversity
Luciano S de Lima, Eric Martineau, Francilaine E De Marchi, Marie-France Palin, Geraldo T Dos Santos, Hélène V Petit
The objective of this study was to develop a technique for carrying out repeated biopsies of the mammary gland of lactating dairy cows that provides enough material to monitor enzyme activities and gene expression in mammary secretory tissue. A total of 16 Holstein cows were subjected to 4 mammary biopsies each at 3-week intervals for a total of 64 biopsies. A 0.75-cm incision was made through the skin and subcutaneous tissue of the mammary gland and a trocar and cannula were inserted using a circular motion...
July 2016: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
Otavio Tavares Ranzani, Daniel Neves Forte, Antonio Carlos Forte, Igor Mimica, Wilma Carvalho Neves Forte
Objective: Ventilator-associated pneumonia (VAP) is the leading type of hospital-acquired infection in ICU patients. The diagnosis of VAP is challenging, mostly due to limitations of the diagnostic methods available. The aim of this study was to determine whether antibody-coated bacteria (ACB) evaluation can improve the specificity of endotracheal aspirate (EA) culture in VAP diagnosis. Methods: We conducted a diagnostic case-control study, enrolling 45 patients undergoing mechanical ventilation...
May 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Ji-Hye Byun, Sun-Hong Kwon, Ji-Hye Ha, Eui-Kyung Lee
PURPOSE: The benefit-risk balance for drugs can alter post approval owing to additional data on efficacy or adverse events. This study developed a quantitative benefit-risk assessment (BRA) model for statins using multicriteria decision analysis with discrete choice experiments and compared a recent BRA with that at the time of approval. PATIENTS AND METHODS: Following a systematic review of the literature, the benefit criteria within the statin BRA model were defined as a reduction in the plasma low-density lipoprotein cholesterol level and a reduction in myocardial infarction incidence; the risk criteria were hepatotoxicity (Liv) and fatal rhabdomyolysis (Rha)...
2016: Therapeutics and Clinical Risk Management
María Victoria Vieiro Medina, Ramón Gómez Sanz, Eneida Bra Insa, Iván Domínguez Sánchez, Marta de la Fuente Bartolomé, David Díaz Pérez, Oana Anisa Nutu, Felipe de la Cruz Vigo
We present the case of a 69 year old woman with a history of cholecystitis, who consulted for severe abdominal pain, nausea and vomiting. Abdominal CT showed duodenal obstruction caused by a gallstone, cholecystoduodenal fistula and pneumobilia, what is known as Bouveret's syndrome, a rare form of gallstone ileus. Additionally, she presented free duodenal and vesicular perforation to retroperitoneum at the same level of the cholecystoduodenal transit point. The patient underwent a difficult cholecystectomy, enterolithotomy, repair of the duodenal defect, extensive washing and drainage of the retroperitoneum...
June 2016: Revista Española de Enfermedades Digestivas
Kashyap Komarraju Tadisina, Gianfranco Frojo, Christina M Plikaitis, Michael L Bernstein
No abstract text is available yet for this article.
October 2016: Plastic and Reconstructive Surgery
Virgílio Gavicho Uarrota, Eduardo da Costa Nunes, Luiz Augusto Martins Peruch, Enilto de Oliveira Neubert, Bianca Coelho, Rodolfo Moresco, Moralba Garcia Domínguez, Teresa Sánchez, Jorge Luis Luna Meléndez, Dominique Dufour, Hernan Ceballos, Luis Augusto Becerra Lopez-Lavalle, Clair Hershey, Miguel Rocha, Marcelo Maraschin
Food losses can occur during production, postharvest, and processing stages in the supply chain. With the onset of worldwide food shortages, interest in reducing postharvest losses in cassava has been increasing. In this research, the main goal was to evaluate biochemical changes and identify the metabolites involved in the deterioration of cassava roots. We found that high levels of ascorbic acid (AsA), polyphenol oxidase (PPO), dry matter, and proteins are correlated with overall lower rates of deterioration...
May 2016: Food Science & Nutrition
Kentaro Tanaka, Kazuto Takada, Eiji Kojima, Takahiro Shimizu, Shohko Miyamatsu, Kango Nohara, Tsutomu Sakurai, Takaaki Mizuno, Yuuki Yamashita
A 69-year-old man visited a clinic for left leg weakness. With suspicions of lung cancer and a metastatic brain tumor, he was referred to our hospital and was diagnosed with large cell neuroendocrine carcinoma, cT1bN0M1b (BRA), stage IV. After stereotactic radiosurgery for his brain metastasis, he was treated with chemotherapy containing cisplatin and irinotecan. A week after initiating chemotherapy, he suddenly developed severe right leg pain and adynamia. A computed tomography angiogram revealed occlusion of the right common femoral artery, and percutaneous thrombectomy was performed...
May 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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