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https://www.readbyqxmd.com/read/28208590/synthesizing-existing-csma-and-tdma-based-mac-protocols-for-vanets
#1
Jiawei Huang, Qi Li, Shaohua Zhong, Lianhai Liu, Ping Zhong, Jianxin Wang, Jin Ye
Many Carrier Sense Multiple Access (CSMA) and Time Division Multiple Access (TDMA) based medium access control (MAC) protocols for vehicular ad hoc networks (VANETs) have been proposed recently. Contrary to the common perception that they are competitors, we argue that the underlying strategies used in these MAC protocols are complementary. Based on this insight, we design CTMAC, a MAC protocol that synthesizes existing strategies; namely, random accessing channel (used in CSMA-style protocols) and arbitral reserving channel (used in TDMA-based protocols)...
February 10, 2017: Sensors
https://www.readbyqxmd.com/read/28132683/probability-of-accurate-heart-failure-diagnosis-and-the-implications-for-hospital-readmissions
#2
Sandra A Carey, Kyle Bass, Giovanna Saracino, Cara A East, Joost Felius, Paul A Grayburn, Ravi C Vallabhan, Shelley A Hall
Heart failure (HF) is a complex syndrome with inherent diagnostic challenges. We studied the scope of possibly inaccurately documented HF in a large health care system among patients assigned a primary diagnosis of HF at discharge. Through a retrospective record review and a classification schema developed from published guidelines, we assessed the probability of the documented HF diagnosis being accurate and determined factors associated with HF-related and non-HF-related hospital readmissions. An arbitration committee of 3 experts reviewed a subset of records to corroborate the results...
January 5, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28126677/artesunate-acts-as-fuel-to-fire-in-sensitizing-hepg2-cells-towards-trail-mediated-apoptosis-via-stat3-inhibition-and-dr4-augmentation
#3
M Ilamathi, V Sivaramakrishnan
In the present study, we investigated in vitro, the role of artesunate (ATS) with comparable potency to oxaliplatin (OXP) in sensitizing tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) resistant HepG2 cells towards apoptosis. ATS in consistency with OXP was found to reverse TRAIL resistant HepG2 cells towards TRAIL mediated apoptosis by enhancing caspase-3 and cleavage of PARP. Additionally, ATS also suppressed the nuclear translocation of activated signal transducers and activators of transcription 3 (STAT3) thereby sensitizing the HepG2 cells towards only death receptor 4 (DR4) mediated apoptosis...
January 23, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28114344/nod1card-might-be-using-multiple-interfaces-for-rip2-mediated-card-card-interaction-insights-from-molecular-dynamics-simulation
#4
Jitendra Maharana, Sukanta Kumar Pradhan, Sachinandan De
The nucleotide-binding and oligomerization domain (NOD)-containing protein 1 (NOD1) plays the pivotal role in host-pathogen interface of innate immunity and triggers immune signalling pathways for the maturation and release of pro-inflammatory cytokines. Upon the recognition of iE-DAP, NOD1 self-oligomerizes in an ATP-dependent fashion and interacts with adaptor molecule receptor-interacting protein 2 (RIP2) for the propagation of innate immune signalling and initiation of pro-inflammatory immune responses...
2017: PloS One
https://www.readbyqxmd.com/read/28088744/self-concept-mediate-the-relationship-between-childhood-maltreatment-and-abstinence-motivation-as-well-as-self-efficacy-among-drug-addicts
#5
Feng-Ying Lu, Si Wen, Gang Deng, Yung-Lung Tang
OBJECTIVE: Childhood maltreatment is widely accepted as a risk factor for drug addiction from adolescence to adulthood. However, the influence of childhood maltreatment on drug treatment related variables, such as drug abstinence motivation and self-concept, as well as self-efficacy, remains unclear. This study aims at exploring whether self-concept mediates the relationship between childhood maltreatment and abstinence motivation, as well as self-efficacy, among drug addicts. METHODS: This study involves 816 (550 males, 226 females, mean age=34...
May 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28062574/loss-of-n-acetylgalactosaminyltransferase-4-orchestrate-oncogenic-microrna-9-in-hepatocellular-carcinoma
#6
Yidong Liu, Haiou Liu, Liu Yang, Qian Wu, Weisi Liu, Qiang Fu, Weijuan Zhang, Haijian Zhang, Jiejie Xu, Jianxin Gu
Deregulated expression of N-acetylgalactosaminyltransferases (GALNTs), which responsible for initiating step of mucin-type O-glycosylation, could produce abnormal truncated O-glycans and thereby exerting pivotal functions during malignant transformation. GALNT4 is one of the few isoforms preferring to catalyze partial GalNAc-glycosylated substrates and modify the sites not utilized by other known GALNTs. This study aims to evaluate the impact of GALNT4 expression on malignant transformation of hepatocellular carcinoma (HCC)...
January 6, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28045884/a-study-of-interpersonal-conflict-among-operating-room-nurses
#7
Tsui-Fen Chang, Chung-Kuang Chen, Ming-Jia Chen
BACKGROUND: Team collaboration is an important factor that affects the performance of the operating room (OR). Therefore, the ability of OR nurses to adapt to and manage interpersonal conflict incidents properly is very important. PURPOSE: The aims of this study were to investigate the interpersonal conflict management capabilities of OR nursing staffs and to find the relationships among the demographics of OR nurses and the following: work-related variables, interpersonal conflict management style, and target of interpersonal conflict...
December 29, 2016: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28025341/can-we-replace-curation-with-information-extraction-software
#8
REVIEW
Peter D Karp
Can we use programs for automated or semi-automated information extraction from scientific texts as practical alternatives to professional curation? I show that error rates of current information extraction programs are too high to replace professional curation today. Furthermore, current IEP programs extract single narrow slivers of information, such as individual protein interactions; they cannot extract the large breadth of information extracted by professional curators for databases such as EcoCyc. They also cannot arbitrate among conflicting statements in the literature as curators can...
2016: Database: the Journal of Biological Databases and Curation
https://www.readbyqxmd.com/read/28024825/automated-diabetic-retinopathy-image-assessment-software-diagnostic-accuracy-and-cost-effectiveness-compared-with-human-graders
#9
Adnan Tufail, Caroline Rudisill, Catherine Egan, Venediktos V Kapetanakis, Sebastian Salas-Vega, Christopher G Owen, Aaron Lee, Vern Louw, John Anderson, Gerald Liew, Louis Bolter, Sowmya Srinivas, Muneeswar Nittala, SriniVas Sadda, Paul Taylor, Alicja R Rudnicka
OBJECTIVE: With the increasing prevalence of diabetes, annual screening for diabetic retinopathy (DR) by expert human grading of retinal images is challenging. Automated DR image assessment systems (ARIAS) may provide clinically effective and cost-effective detection of retinopathy. We aimed to determine whether ARIAS can be safely introduced into DR screening pathways to replace human graders. DESIGN: Observational measurement comparison study of human graders following a national screening program for DR versus ARIAS...
December 23, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27995269/-new-legal-regulations-for-palliative-care-with-implications-for-politics-and-practice
#10
Heiner Melching
In December 2015 two different laws were adopted. Both are of importance for palliative care. One of the laws criminalizes commercial, "business-like" assisted suicide (§ 217 German Criminal Code), the other one aims to improve hospice and palliative care in Germany. Through the latter far-reaching changes in Social Code Books V and XI, as well as of the Hospital Finance Act have been made. This new Act to Improve Hospice and Palliative Care (HPG) focuses, amongst others, on: (a) Better funding of hospice services, by raising the minimum grant for patients in inpatient hospices paid per day by the health insurance funds by about 28...
January 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27994941/a-multisite-validation-of-whole-slide-imaging-for-primary-diagnosis-using-standardized-data-collection-and-analysis
#11
Katy Wack, Laura Drogowski, Murray Treloar, Andrew Evans, Jonhan Ho, Anil Parwani, Michael C Montalto
CONTEXT: Text-based reporting and manual arbitration for whole slide imaging (WSI) validation studies are labor intensive and do not allow for consistent, scalable, and repeatable data collection or analysis. OBJECTIVE: The objective of this study was to establish a method of data capture and analysis using standardized codified checklists and predetermined synoptic discordance tables and to use these methods in a pilot multisite validation study. METHODS AND STUDY DESIGN: Fifteen case report form checklists were generated from the College of American Pathology cancer protocols...
2016: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/27987628/arbitration-board-setting-reimbursement-amounts-for-pharmaceutical-innovations-in-germany-when-price-negations-between-payers-and-manufacturers-fail-an-empirical-analysis-of-5-years-experience
#12
Saskia Ludwig, Charalabos-Markos Dintsios
BACKGROUND: In Germany, an arbitration board is setting reimbursement amounts for drug innovations when price negations between payers and manufacturers fail. OBJECTIVE: To empirically analyze all arbitrations since the reform of Germany's Act to Reorganize the Pharmaceuticals' Market in the Statutory Health Insurance System came into effect. METHODS: All available relevant documents up to January 2016 were screened and the identified contentious issues between the negotiation parties extracted...
December 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27981917/an-observational-study-to-assess-if-automated-diabetic-retinopathy-image-assessment-software-can-replace-one-or-more-steps-of-manual-imaging-grading-and-to-determine-their-cost-effectiveness
#13
Adnan Tufail, Venediktos V Kapetanakis, Sebastian Salas-Vega, Catherine Egan, Caroline Rudisill, Christopher G Owen, Aaron Lee, Vern Louw, John Anderson, Gerald Liew, Louis Bolter, Clare Bailey, SriniVas Sadda, Paul Taylor, Alicja R Rudnicka
BACKGROUND: Diabetic retinopathy screening in England involves labour-intensive manual grading of retinal images. Automated retinal image analysis systems (ARIASs) may offer an alternative to manual grading. OBJECTIVES: To determine the screening performance and cost-effectiveness of ARIASs to replace level 1 human graders or pre-screen with ARIASs in the NHS diabetic eye screening programme (DESP). To examine technical issues associated with implementation. DESIGN: Observational retrospective measurement comparison study with a real-time evaluation of technical issues and a decision-analytic model to evaluate cost-effectiveness...
December 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27981181/stress-potentiates-decision-biases-a-stress-induced-deliberation-to-intuition-sidi-model
#14
REVIEW
Rongjun Yu
Humans often make decisions in stressful situations, for example when the stakes are high and the potential consequences severe, or when the clock is ticking and the task demand is overwhelming. In response, a whole train of biological responses to stress has evolved to allow organisms to make a fight-or-flight response. When under stress, fast and effortless heuristics may dominate over slow and demanding deliberation in making decisions under uncertainty. Here, I review evidence from behavioral studies and neuroimaging research on decision making under stress and propose that stress elicits a switch from an analytic reasoning system to intuitive processes, and predict that this switch is associated with diminished activity in the prefrontal executive control regions and exaggerated activity in subcortical reactive emotion brain areas...
June 2016: Neurobiology of Stress
https://www.readbyqxmd.com/read/27970978/arbitration-board-setting-reimbursement-amounts-for-pharmaceutical-innovations-in-germany-when-price-negations-between-payors-and-manufacturers-fail-an-empirical-analysis-of-5-years-experience
#15
S Ludwig, C Dintsios
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27919191/phytotherapeutic-approach-a-new-hope-for-polycyclic-aromatic-hydrocarbons-induced-cellular-disorders-autophagic-and-apoptotic-cell-death
#16
Durgesh Nandini Das, Prashanta Kumar Panda, Prajna Paramita Naik, Subhadip Mukhopadhyay, Niharika Sinha, Sujit K Bhutia
Polycyclic aromatic hydrocarbons (PAHs) comprise the major class of cancer-causing chemicals and are ranked ninth among the chemical compounds threatening to humans. Moreover, interest in PAHs has been mainly due to their carcinogenic property, these compounds are genotoxic, teratogenic, mutagenic, and carcinogenic. Polymorphism in cytochrome P450 (CYP450) and aryl hydrocarbon receptor (AhR) have the capacity to convert procarcinogens into carcinogens, which is an imperative factor contributing to individual susceptibility to cancer development...
December 5, 2016: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/27880893/postoperative-outcomes-and-quality-of-life-following-hysterectomy-by-natural-orifice-transluminal-endoscopic-surgery-notes-compared-to-laparoscopy-in-women-with-a-non-prolapsed-uterus-and-benign-gynaecological-disease-a-systematic-review-and-meta-analysis
#17
REVIEW
Jan Baekelandt, Peter A De Mulder, Ilse Le Roy, Chantal Mathieu, Annouschka Laenen, Paul Enzlin, Steven Weyers, Ben W J Mol, Jan J A Bosteels
OBJECTIVE: To critically appraise studies comparing benefits and harms in women with benign disease without prolapse undergoing hysterectomy by natural orifice transluminal endoscopic surgery (NOTES) versus laparoscopy. STUDY DESIGN: We followed the PRISMA guidelines. We searched MEDLINE, EMBASE and CENTRAL for randomised controlled trials (RCTs), controlled clinical trials (CCTs) and cohort studies comparing NOTES with laparoscopy assisted vaginal hysterectomy (LAVH) or total laparoscopic hysterectomy (TLH) in women bound to undergo removal of a non-prolapsed uterus for benign disease...
January 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27879256/determination-and-regulation-of-body-composition-in-elite-athletes
#18
Peter Sonksen
In 2011, the International Association of Athletics Federations (IAAF) and IOC introduced a 'hyperandrogenism' rule that excluded women with a serum testosterone >10 nmol/L from participating in elite sport. This rule was based on the false premise that the greater lean body mass in men was a consequence of their higher serum testosterone. This rule did not have scientific backing and the Court of Arbitration for Sport subsequently rescinded the rule following an appeal from an Indian athlete barred from the Commonwealth Games...
November 22, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27861469/-the-national-medical-arbitration-commission-20-years
#19
Juan Ramón de la Fuente
Cuando la Secretaría de Salud todavía tenía el logotipo azul que decía SSA, corrían tiempos difíciles porque no había dinero y la idea de crear nuevas instituciones era recibida con reservas, no sólo por el Presidente Zedillo, siempre generoso y atento a las necesidades de salud de la población, sino también, como ya es costumbre, por el secretario de Hacienda, responsable de cuidar el erario público. Y es que la idea de hacer crecer el gasto corriente del gobierno se percibía, no sin razón, como un acto que podía infligir el riesgo de fomentar estructuras administrativas ineficaces y obesas...
November 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27831623/-alternative-mechanisms-for-conflict-resolution-in-the-context-of-health-rights-the-peruvian-experience-from-the-center-for-reconciliation-and-arbitration-of-the-national-health-authority
#20
Darwin Hidalgo-Salas, Claudia Ortiz-Pérez, Juan Lobatón-Flores, Percy Huamaní-Ñahuinlla, Edward Mezones-Holguín
In Peru the right to health protection is constitutionally recognized. The right to access health services is legally mandated, as well as access to health information and the protection of rights such as informed consent. However, with the implementation of actions related to these rights and protections, there may be disagreements which need to be resolved. In this context, alternative mechanisms for conflict resolution (AMCR), such as mediation, reconciliation and arbitration, are valid and accessible strategies within the Peruvian Health System...
July 2016: Revista Peruana de Medicina Experimental y Salud Pública
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