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Aeroallergen

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https://www.readbyqxmd.com/read/28915125/air-pollution-aeroallergens-and-suicidality-a-review-of-the-effects-of-air-pollution-and-aeroallergens-on-suicidal-behavior-and-an-exploration-of-possible-mechanisms
#1
Renee-Marie Ragguett, Danielle S Cha, Mehala Subramaniapillai, Nicole E Carmona, Yena Lee, Duanduan Yuan, Carola Rong, Roger S McIntyre
OBJECTIVE: Risk factors for suicide can be broadly categorized as sociodemographic, clinical and treatment. There is interest in environmental risk and protection factors for suicide. Emerging evidence suggests a link between environmental factors in the form of air pollution and aeroallergens in relation to suicidality. METHODS: Herein, we conducted a systematic review of 15 articles which have met inclusion criteria on the aforementioned effects. RESULTS: The majority of the reviewed articles reported an increased suicide risk alongside increased air pollutants or aeroallergens (i...
September 15, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28913990/association-between-sensitization-to-mold-and-impaired-pulmonary-function-in-children-with-asthma
#2
Jung Hye Byeon, Soohyun Ri, Oyuntulga Amarsaikhan, Eunji Kim, So Hyun Ahn, Ic Sun Choi, Hyung Jin Kim, SungChul Seo, Wonsuck Yoon, Young Yoo
PURPOSE: Recent data indicate that sensitization to mold contributes to the severity and persistence of asthma. In this study, we investigated the relationships between sensitization to mold and lung function parameters in children with asthma. METHODS: We retrospectively reviewed clinical data from 551 asthmatic subjects. We selected subjects who met clinical diagnostic criteria of asthma. Their spirometry, methacholine challenge tests, and measurements of blood eosinophils, serum IgE, eosinophil cationic protein (ECP) and fractional exhaled nitric oxide (FeNO) results were included...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28913989/patterns-of-inhalant-allergen-sensitization-and-geographical-variation-in-korean-adults-a-multicenter-retrospective-study
#3
Min Gyu Kang, Mi Yeong Kim, Woo Jung Song, Sujeong Kim, Eun Jung Jo, Seung Eun Lee, Jae Woo Kwon, Sang Min Lee, Chan Sun Park, Hye Kyung Park, Heung Woo Park, Yoon Seok Chang, Jaechun Lee, Young Min Lee, Young Koo Jee, Jong Myung Lee, Inseon S Choi, Sang Heon Cho
PURPOSE: Inhalant allergen sensitization is one of the major factors involved in the pathogenesis of allergic respiratory diseases. However, the sensitization is determined by interactions between genetic and environmental factors. Thus, testing panels of inhalant allergens may differ among geographical areas. Here we aimed to determine 10 common inhalant allergens in Korean adult patients with suspected respiratory allergies and to examine the variation between different geographical locations...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28882557/exposure-amount-and-timing-of-solar-irradiation-during-pregnancy-and-the-risk-of-sensitization-in-children
#4
Hyun Yong Koh, Eunhae Cho, So-Yeon Lee, Woo Kyung Kim, Yong Mean Park, Jihyun Kim, Kangmo Ahn, Seung Won Lee, Mi Ae Kim, Myung-Il Hahm, Yoomi Chae, Kee-Jae Lee, Ho-Jang Kwon, Man Yong Han
BACKGROUND: Solar irradiation affects sensitization to aeroallergens and the prevalence of allergic diseases. Little is known, however, about how the time and amount of solar irradiation during pregnancy affects such risks in children. We aimed to find out how solar irradiation during pregnancy affects sensitization to aero-allergens and the prevalence of allergic diseases in children. METHODS: This population-based cross-sectional study involved 7301 aged 6 years and aged 12 years children...
September 4, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28874741/a-functional-ifn-%C3%AE-4-generating-dna-polymorphism-could-protect-older-asthmatic-women-from-aeroallergen-sensitization-and-associate-with-clinical-features-of-asthma
#5
Sreedhar Chinnaswamy, Aleksandra Wardzynska, Malgorzata Pawelczyk, Joanna Makowska, Tea Skaaby, Josep M Mercader, Tarunveer S Ahluwalia, Niels Grarup, Marta Guindo-Martinez, Hans Bisgaard, David Torrents, Allan Linneberg, Klaus Bønnelykke, Marek L Kowalski
Lambda interferons (IFNLs) have immunomodulatory functions at epithelial barrier surfaces. IFN-λ4, a recent member of this family is expressed only in a subset of the population due to a frameshift-causing DNA polymorphism rs368234815. We examined the association of this polymorphism with atopy (aeroallergen sensitization) and asthma in a Polish hospital-based case-control cohort comprising of well-characterized adult asthmatics (n = 326) and healthy controls (n = 111). In the combined cohort, we saw no association of the polymorphism with asthma and/or atopy...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28870462/food-diversity-during-the-first-year-of-life-and-allergic-diseases-until-15-years
#6
Iana Markevych, Marie Standl, Irina Lehmann, Andrea von Berg, Joachim Heinrich
Higher food diversity during the first year of life appears to decrease the risk of allergic sensitization to aeroallergens up to 15 years only among children with early skin symptoms in German birth cohort.
September 1, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28865410/decreased-sensitization-to-aeroallergens-among-southwestern-iranian-male-farmers
#7
Mozhgan Moghtaderi, Mona Torab Jahromi, Shirin Farjadian, Payam Ghassemi, Saeed Hosseini Teshnizi
Farmers are usually exposed to various inhaled allergens like pollens, mites, molds, and animal dander in their working environment which may lead to allergic rhinitis, asthma and urticaria. The purpose of this study was to identify sensitization to various aeroallergens in farmers and their occupational allergy symptoms. This cross sectional study included 103 male farmers and 100 non-farmer healthy controls. The work-related symptoms of farmers were recorded with a questionnaire. Spirometry and skin prick tests with 15 commercial allergen extracts were performed in both farmers and controls...
August 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28865409/determination-of-the-most-common-indoor-and-outdoor-allergens-in-602-patients-with-allergic-symptoms-using-specific-ige-local-panel
#8
Raheleh Shokouhi Shoormasti, Zahra Pourpak, Mohammad Reza Fazlollahi, Azadeh Shabani, Anoshirvan Kazemnejad, Zahra Ebadi, Behnoosh Tayebi, Behzad Darabi, Masoud Movahedi, Seyed Alireza Mahdaviani, Mostafa Moin
Aeroallergens play an important role in developing allergic diseases. The aim of this study was to determine the outdoor and indoor sensitization using a specific regional panel of aeroallergens in allergic patients. All patients with allergic symptoms referred to Immunology, Asthma and Allergy Research Institute (IAARI) in Tehran, Iran from December 2010 to July 2013 entered this cross sectional study. We evaluated serum samples for specific IgE against 20 selected aeroallergens provided by a specific panel (RIDA Allergy Screen test, IAARI panel)...
August 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28865233/first-allergenic-pollen-monitoring-in-bucharest-and-results-of-three-years-collaboration-with-european-aerobiology-specialists
#9
Polliana Mihaela Leru, Ana-Maria Eftimie, Michel Thibaudon
INTRODUCTION: Respiratory allergies induced by allergenic plants pollen represent an important public health problem with increasing prevalence and severity. Aerobiologic study of allergenic pollens is performed in many countries on regular basis and correlated with health data from allergists in the frame of national aerobiology networks. Romania has no aerobiology network and pollen measurements have been done between 1999-2012 in West region only. In the frame of COST Action called Sustainable management of Ambrosia Artemisiifolia in Europe (SMARTER FA 1203), three years collaboration with Reseau National de Surveillance Aerobiologique (RNSA) from France and the first pollen monitoring center in Bucharest were established...
August 28, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28855606/a-cross-sectional-observational-study-on-allergen-specific-ige-positivity-in-a-southeast-coastal-versus-a-southwest-inland-region-of-china
#10
Guangqiao Zeng, Wenting Luo, Zehong Wu, Ling Li, Peiyan Zheng, Huimin Huang, Nili Wei, Jiaying Luo, Baoqing Sun, Yong Liu
Few studies addressed trans-regional differences in allergen sensitization between areas within a similar latitudinal range but with distinct geomorphological features. We investigated specific IgE (sIgE) positivity to common allergens in populations from two southern China provinces. Using a uniformed protocol, serum samples were collected from 2778 subjects with suspected atopy in coastal Guangdong and inland Yunnan. The overall prevalence of sIgE positivity were 57.8% (95% CI: 56.0%, 59.6%) from Guangdong vs 60...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28853977/immunotherapy-of-house-dust-mite-allergy
#11
Lin Yang, Rongfei Zhu
House dust mite (HDM) is a predominant source of indoor aeroallergen worldwide, which induces allergic diseases including allergic rhinoconjunctivitis, allergic asthma, atopic eczema and other allergic skin diseases. Allergen specific immunotherapy (AIT) is the only potential disease-modifying treatment for HDM allergic subjects. However, AIT remains underused due to no universally accepted allergen standardization and a shortage of rigorous clinical studies to confirm safety and efficacy. With the effort of doctors and researchers in allergy field, efficacy, safety, standardization and strategy of AIT are being continuously developed...
August 30, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28839248/sensitization-patterns-and-minimum-screening-panels-for-aeroallergens-in-self-reported-allergic-rhinitis-in-china
#12
Hongfei Lou, Siyuan Ma, Yan Zhao, Feifei Cao, Fei He, Zhongyan Liu, Jean Bousquet, Chengshuo Wang, Luo Zhang, Claus Bachert
Optimization of skin prick test (SPT) panels, especially in view of significant differences in sensitizations patterns within different geographical areas, is an unmet need within China. Our aim was to assess the patterns and clinical relevance of aeroallergen sensitizations in allergic rhinitis (AR) and define the minimal battery of SPT allergens, classified according to the Köppen-Geiger climate map. Overall, 7148 subjects with self-reported AR completed a standard questionnaire and were assessed for sensitization to relevant allergens by SPT...
August 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28815996/age-related-changes-in-childhood-wheezing-characteristics-a-whole-population-study
#13
Maja Jurca, Anina M Pescatore, Myrofora Goutaki, Ben D Spycher, Caroline S Beardsmore, Claudia E Kuehni
BACKGROUND: Wheezing illnesses are characterized by phenotypic variability, which changes with age, but few studies report on a wide age range of children. We studied how prevalence, severity, and triggers of wheeze vary throughout childhood. METHODS: We analyzed data from a large population-based cohort of children from Leicestershire, UK, who were followed from infancy through late adolescence using postal questionnaires. We used generalized estimating equations to describe age-related changes in prevalence of any wheeze: episodic viral and multiple trigger wheeze; wheeze triggered by exercise, aeroallergens, food/drinks, laughing/crying; and of severe wheeze (frequent attacks, shortness of breath, sleep disturbance, disturbance of daily activities) from age 1-18 years...
August 16, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28814357/association-of-aeroallergen-sensitization-and-atopic-disease-in-the-sonoran-desert
#14
Ryan D Buckley, Tara F Carr
BACKGROUND: Numerous aeroallergens have been associated with the development of asthma, including Alternaria, house-dust mite, and pet dander. Tucson, Arizona, is located in the Sonoran Desert, which has the highest diversity of vegetation of any desert in the world. Given the unique pollen profile in this region, we sought to identify the most common aeroallergens associated with rhinitis and asthma diagnosis in the local adult population. OBJECTIVE: To identify the prevalence of aeroallergen sensitivity in the Tucson adult population and to identify which aeroallergens are associated with a diagnosis of asthma...
September 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28807539/murine-models-for-mucosal-tolerance-in-allergy
#15
REVIEW
Ursula Smole, Irma Schabussova, Winfried F Pickl, Ursula Wiedermann
Immunity is established by a fine balance to discriminate between self and non-self. In addition, mucosal surfaces have the unique ability to establish and maintain a state of tolerance also against non-self constituents such as those represented by the large numbers of commensals populating mucosal surfaces and food-derived or air-borne antigens. Recent years have seen a dramatic expansion in our understanding of the basic mechanisms and the involved cellular and molecular players orchestrating mucosal tolerance...
August 11, 2017: Seminars in Immunology
https://www.readbyqxmd.com/read/28747837/evaluation-of-pulmonary-functions-in-preschool-children-born-late-preterm
#16
İlkay Er, Ayla Günlemez, Zeynep Seda Uyan, Metin Aydoğan, Meral Oruç, Olcay Işık, Ayşe Engin Arısoy, Canan Baydemir, Ayşe Sevim Gökalp
AIM: The aim of this study was to evaluate the pulmonary functions of preschool children born late-preterm. MATERIAL AND METHODS: Children aged between 3-7 years who were born at 34(0/7-)36(6/7) weeks' gestation represented the target sample. Patients with a diagnosis of congenital cardiac, pulmonary and/or muscle diseases were excluded. Respiratory symptoms were evaluated using the modified asthma predictive index and International Study of Asthma and Allergies in Childhood criteria for children aged under and over 6 years, respectively...
June 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28745029/adam10-and-notch1-on-murine-dendritic-cells-control-the-development-of-type-2-immunity-and-ige-production
#17
Sheela R Damle, Rebecca K Martin, Chelsea L Cockburn, Joseph C Lownik, Jason A Carlyon, Allen D Smith, Daniel H Conrad
BACKGROUND: Allergy and allergic asthma are significant health burdens in developed countries and are increasing in prevalence. Dendritic cells (DCs) initiate immune responses to common aeroallergens and ADAM10 has been demonstrated to be important for the development of adaptive responses. This study's objective was to understand the role of ADAM10 on DCs in the development of allergic and anaphylactic responses. METHODS: In this study we used mouse models of allergic airway inflammation (house dust mice and Alternaria alternata) and OVA-induced models of active anaphylaxis to determine the DC-specific function of ADAM10 and Notch signaling...
July 26, 2017: Allergy
https://www.readbyqxmd.com/read/28736450/screening-survey-of-ocular-nasal-respiratory-and-skin-symptoms-in-manicurists-in-poland
#18
Marta Kieć-Świerczyńska, Dominika Świerczyńska-Machura, Dorota Chomiczewska-Skóra, Beata Kręcisz, Jolanta Walusiak-Skorupa
OBJECTIVES: Manicurists are exposed to various chemicals in nail and skin care products and may develop ocular, nasal, respiratory or skin adverse reactions to them. To investigate the occurrence of ocular, nasal, respiratory and skin problems among manicurists and to identify their causal factors, particularly allergic etiology and occupational origin. MATERIAL AND METHODS: Manicurists employed in beauty salons in the central region of Poland were invited to fill in the questionnaire and undergo medical examination, skin prick tests with common aeroallergens, patch tests with European Baseline Series and (Meth)Acrylates Series-Nails and spirometry...
July 12, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28727997/therapeutic-intranasal-instillation-of-allergen-loaded-microbubbles-suppresses-experimental-allergic-asthma-in-mice
#19
Blaise Corthésy, Gilles Bioley
Despite proven efficiency, subcutaneous immunotherapy for aeroallergens is impaired by the duration of the protocol, the repeated injections and potential side-effects associated with the doses of allergen administered. Intranasal delivery of immunotherapeutic agents may overcome several of these drawbacks, provided that an efficient allergen delivery vehicle can be identified. This study evaluates whether intranasally delivered gas-filled microbubble (MB)-associated ovalbumin (OVA), used as a model allergen, can serve as a therapeutic treatment in a mouse model of established allergic asthma...
October 2017: Biomaterials
https://www.readbyqxmd.com/read/28724883/calcium-prepartions-do-not-inhibit-allergic-reactions-a-randomized-controlled-trial
#20
Klaudia Matysiak, Michał Matuszewski, Wojciech Feleszko
INTRODUCTION    Massive consumption of dietary supplements, including vitamins and minerals, has recently became a serious public issue in Europe. When ingested, they may negatively affect pharmacological activity of various medications, including anti-allergic drugs. Calcium preparations are well-known and commonly used in some European countries as a popular remedy for allergy-related skin reactions, such as itching, erythema and wheals, as well as insect bites. However, their action has not been reliably proven yet...
June 27, 2017: Polish Archives of Internal Medicine
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