keyword
https://read.qxmd.com/read/38413459/uri-cads-a-fully-automated-computer-aided-diagnosis-system-for-ultrasound-renal-imaging
#21
JOURNAL ARTICLE
Miguel Molina-Moreno, Iván González-Díaz, Maite Rivera Gorrín, Víctor Burguera Vion, Fernando Díaz-de-María
Ultrasound is a widespread imaging modality, with special application in medical fields such as nephrology. However, automated approaches for ultrasound renal interpretation still pose some challenges: (1) the need for manual supervision by experts at various stages of the system, which prevents its adoption in primary healthcare, and (2) their limited considered taxonomy (e.g., reduced number of pathologies), which makes them unsuitable for training practitioners and providing support to experts. This paper proposes a fully automated computer-aided diagnosis system for ultrasound renal imaging addressing both of these challenges...
February 27, 2024: J Imaging Inform Med
https://read.qxmd.com/read/38402922/prognostic-impact-of-previous-atherosclerotic-cardiovascular-disease-on-short-and-long-term-outcomes-in-acute-myocardial-infarction
#22
JOURNAL ARTICLE
Yuichi Saito, Hiroaki Yaginuma, Kazunari Asada, Hiroki Goto, Takanori Sato, Hideki Kitahara, Yoshio Kobayashi
Patients with previous atherosclerotic cardiovascular disease (ASCVD) are typically managed by secondary prevention modalities, but they may experience recurrent events. In acute myocardial infarction (MI), the prognostic effect of pre-existing ASCVD on short- and long-term outcomes remains uncertain. This retrospective multicenter registry included 2475 patients with acute MI who had undergone percutaneous coronary intervention. Previous ASCVD was defined as a history of ischemic events in the coronary, cerebral, and peripheral arterial territories...
February 23, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38390201/clinical-characteristics-and-degree-of-cardiovascular-risk-factor-control-in-patients-with-newly-diagnosed-type-2-diabetes-in-catalonia
#23
JOURNAL ARTICLE
Anna Ramírez-Morros, Josep Franch-Nadal, Jordi Real, Queralt Miró-Catalina, Magdalena Bundó, Bogdan Vlacho, Didac Mauricio
INTRODUCTION: Women with type 2 diabetes mellitus (T2DM) face a greater risk of cardiovascular disease (CVD) and encounter challenges in managing cardiovascular risk factors (CVRF); however, limited data are available in individuals with newlydiagnosed T2DM. METHODS: This study aimed to examine differences between women and men at the onset of T2DM in terms of clinical characteristics, glycaemic status, and CVRF management. This was a retrospective cohort study including subjects with newly-diagnosed T2DM from the System for the Development of Research in Primary Care (SIDIAP) database in Catalonia (Spain)...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38385916/nitroglycerin-to-ameliorate-coronary-artery-spasm-during-focal-pulsed-field-ablation-for-atrial-fibrillation
#24
JOURNAL ARTICLE
Yury Malyshev, Petr Neuzil, Jan Petru, Moritoshi Funasako, Pavel Hala, Karel Kopriva, Christopher Schneider, Anitha Achyutha, Annelies Vanderper, Daniel Musikantow, Mohit Turagam, Srinivas R Dukkipati, Vivek Y Reddy
BACKGROUND: In treating atrial fibrillation, pulsed-field ablation (PFA) has comparable efficacy to conventional thermal ablation, but with important safety advantages: no esophageal injury or pulmonary vein stenosis, and rare phrenic nerve injury. However, when PFA is delivered in proximity to coronary arteries using a pentaspline catheter, which generates a broad electrical field, severe vasospasm can be provoked. OBJECTIVES: The authors sought to study the vasospastic potential of a focal PFA catheter with a narrower electrical field and develop a preventive strategy with nitroglycerin...
February 7, 2024: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/38381407/effects-of-pitavastatin-on-coronary-artery-disease-and-inflammatory-biomarkers-in-hiv-mechanistic-substudy-of-the-reprieve-randomized-clinical-trial
#25
JOURNAL ARTICLE
Michael T Lu, Heather Ribaudo, Borek Foldyna, Markella V Zanni, Thomas Mayrhofer, Julia Karady, Jana Taron, Kathleen V Fitch, Sara McCallum, Tricia H Burdo, Kayla Paradis, Sandeep S Hedgire, Nandini M Meyersohn, Christopher DeFilippi, Carlos D Malvestutto, Audra Sturniolo, Marissa Diggs, Sue Siminski, Gerald S Bloomfield, Beverly Alston-Smith, Patrice Desvigne-Nickens, Edgar T Overton, Judith S Currier, Judith A Aberg, Carl J Fichtenbaum, Udo Hoffmann, Pamela S Douglas, Steven K Grinspoon
IMPORTANCE: Cardiovascular disease (CVD) is increased in people with HIV (PWH) and is characterized by premature noncalcified coronary plaque. In the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), pitavastatin reduced major adverse cardiovascular events (MACE) by 35% over a median of 5.1 years. OBJECTIVE: To investigate the effects of pitavastatin on noncalcified coronary artery plaque by coronary computed tomography angiography (CTA) and on inflammatory biomarkers as potential mechanisms for MACE prevention...
February 21, 2024: JAMA Cardiology
https://read.qxmd.com/read/38378735/primary-results-of-the-brazilian-registry-of-atherothrombotic-disease-neat
#26
JOURNAL ARTICLE
Pedro G M de Barros E Silva, Charlene Troiani do Nascimento, Rodrigo Pinto Pedrosa, Marcelo Arruda Nakazone, Michel Ulloffo do Nascimento, Leiliandry de Araújo Melo, Osvaldo Lourenço Silva Júnior, Sérgio Luiz Zimmermann, Rodrigo Morel Vieira de Melo, Ricardo Reinaldo Bergo, Dalton Bertolim Precoma, Lucas Tramujas, Eduardo Gomes Lima, João Miguel Malta Dantas, Antônio Cláudio do Amaral Baruzzi, Ronald Luiz Gomes Flumignan, Maria Sanali Moura de Oliveira Paiva, Luís Henrique Wolff Gowdak, Priscila Nasser de Carvalho, José Albuquerque de Figueiredo Neto, Odilson Marcos Silvestre, Alexandre Fioranelli, Ricardo D 'Oliveira Vieira, Ana Clara Peneluppi Horak, Debora Harumi Kodama Miyada, Flávia Cristina Soares Kojima, Júlia Souza de Oliveira, Leila de Oliveira Silva, Ricardo Pavanello, Eduardo Ramacciotti, Renato D Lopes
There is limited contemporary prospective real-world evidence of patients with chronic arterial disease in Latin America. The Network to control atherothrombosis (NEAT) registry is a national prospective observational study of patients with known coronary (CAD) and/or peripheral arterial disease (PAD) in Brazil. A total of 2,005 patients were enrolled among 25 sites from September 2020 to March 2022. Patient characteristics, medications and laboratorial data were collected. Primary objective was to assess the proportion of patients who, at the initial visit, were in accordance with good medical practices (domains) for reducing cardiovascular risk in atherothrombotic disease...
February 20, 2024: Scientific Reports
https://read.qxmd.com/read/38355265/ticagrelor-vs-clopidogrel-for-complex-percutaneous-coronary-intervention-in-chronic-coronary-syndrome
#27
RANDOMIZED CONTROLLED TRIAL
Benoit Lattuca, Cedric Mazeau, Guillaume Cayla, Grégory Ducrocq, Paul Guedeney, Mikael Laredo, Raphaëlle Dumaine, Mohamad El Kasty, Petr Kala, Mohammed Nejjari, Ota Hlinomaz, Olivier Morel, Olivier Varenne, Florence Leclercq, Laurent Payot, Christian Spaulding, Farzin Beygui, Grégoire Rangé, Zuzana Motovska, Jean-Jacques Portal, Eric Vicaut, Jean-Philippe Collet, Gilles Montalescot, Johanne Silvain
BACKGROUND: Whether ticagrelor in chronic coronary syndrome patients undergoing complex percutaneous coronary intervention (PCI) can prevent cardiovascular events is unknown. OBJECTIVES: The authors sought to evaluate outcomes of complex PCI and the efficacy of ticagrelor vs clopidogrel in stable patients randomized in the ALPHEUS (Assessment of Loading with the P2Y12 inhibitor ticagrelor or clopidogrel to Halt ischemic Events in patients Undergoing elective coronary Stenting) trial...
February 12, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38348779/age-and-aspirin-dosing-in-secondary-prevention-of-atherosclerotic-cardiovascular-disease
#28
JOURNAL ARTICLE
Guillaume Marquis-Gravel, Amanda Stebbins, Lisa M Wruck, Matthew T Roe, Mark B Effron, Bradley G Hammill, Jeff Whittle, Jeffrey J VanWormer, Holly R Robertson, Jacqueline D Alikhaani, Sunil Kripalani, Peter M Farrehi, Saket Girotra, Catherine P Benziger, Tamar S Polonsky, J Greg Merritt, Kamal Gupta, Thomas E McCormick, Kirk U Knowlton, Sandeep K Jain, Ajar Kochar, Russell L Rothman, Robert A Harrington, Adrian F Hernandez, W Schuyler Jones
BACKGROUND: In patients with atherosclerotic cardiovascular disease, increasing age is concurrently associated with higher risks of ischemic and bleeding events. The objectives are to determine the impact of aspirin dose on clinical outcomes according to age in atherosclerotic cardiovascular disease. METHODS AND RESULTS: In the ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) trial, patients with atherosclerotic cardiovascular disease were randomized to daily aspirin doses of 81 mg or 325 mg...
February 13, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38348663/carbonylation-of-runx2-at-k176-by-4-hydroxynonenal-accelerates-vascular-calcification
#29
JOURNAL ARTICLE
Xiaoxuan Zhai, Shengchuan Cao, Jiali Wang, Bao Qiao, Xuehao Liu, Rui Hua, Menglin Zhao, Shukun Sun, Yu Han, Shuo Wu, Jiaojiao Pang, Qiuhuan Yuan, Bailu Wang, Feng Xu, Shujian Wei, Yuguo Chen
BACKGROUND: Vascular calcification, which is characterized by calcium deposition in arterial walls and the osteochondrogenic differentiation of vascular smooth muscle cells, is an actively regulated process that involves complex mechanisms. Vascular calcification is associated with increased cardiovascular adverse events. The role of 4-hydroxynonenal (4-HNE), which is the most abundant stable product of lipid peroxidation, in vascular calcification has been poorly investigated. METHODS: Serum was collected from patients with chronic kidney disease and controls, and the levels of 4-HNE and 8-iso-prostaglandin F2α were measured...
February 13, 2024: Circulation
https://read.qxmd.com/read/38337564/repeat-coronary-angiography-in-patients-aged-over-50-years-with-previously-normal-non-obstructive-coronary-angiogram-insights-from-a-retrospective-study
#30
JOURNAL ARTICLE
Ariel Roguin, Ofer Kobo, Simha-Ron Meisel, Ziad Darawsha, Mahmood Odeh, Aharon Frimerman, Naama Amsalem, Rami Abu Fanne
(1) Introduction : A significant proportion of patients undergoing coronary angiography (CAG) have normal (NCA) or non-obstructive coronary artery disease (NOCAD). This study retrospectively tested the incidence of re-catheterization, and long-term outcomes of this population in patients aged over 50 years. (2) Methods : We identified all patients above 50 years of age with NOCAD who underwent their first CAG at our center between January 2008 and December 2019. Patients were evaluated for their baseline characteristics, risk factors profile, and indication for CAG...
February 2, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38328918/diastolic-dysfunction-as-a-positive-predictor-of-recurrent-vascular-events-in-patients-with-noncardioembolic-stroke
#31
JOURNAL ARTICLE
Kentaro Ishizuka, Takao Hoshino, Takafumi Mizuno, Shuntaro Takahashi, Sho Wako, Satoko Arai, Sono Toi, Kazuo Kitagawa
BACKGROUND: This study aimed to assess the effects of left ventricular diastolic dysfunction (LVDD) on vascular outcomes among patients with stroke of noncardioembolic origins. METHODS: This prospective observational study enrolled 563 patients with noncardioembolic stroke (mean age, 67.9 years; 66.7% men and 33.3% women individuals) registered in the Tokyo Women's Medical University Stroke Registry between 2013 and 2020. Then, patients were divided into the LVDD and non-LVDD groups...
March 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38325523/plasma-proteomics-for-prediction-of-subclinical-coronary-artery-calcifications-in-primary-prevention
#32
JOURNAL ARTICLE
Patrick Royer, Elias Björnson, Martin Adiels, María Bueno Álvez, Linn Fagerberg, Fredrik Bäckhed, Mathias Uhlén, Anders Gummesson, Göran Bergström
BACKGROUND AND AIMS: Recent developments in high-throughput proteomic technologies enable the discovery of novel biomarkers of coronary atherosclerosis. The aims of this study were to test if plasma protein subsets could detect coronary artery calcifications (CAC) in asymptomatic individuals and if they add predictive value beyond traditional risk factors. METHODS: Using proximity extension assays, 1342 plasma proteins were measured in 1827 individuals from the Impaired Glucose Tolerance and Microbiota (IGTM) study and 883 individuals from the Swedish Cardiopulmonary BioImage Study (SCAPIS) aged 50-64 years without history of ischaemic heart disease and with CAC assessed by computed tomography...
February 5, 2024: American Heart Journal
https://read.qxmd.com/read/38323698/small-dense-low-density-lipoprotein-cholesterol-and-coronary-artery-calcification-in-the-multi-ethnic-study-of-atherosclerosis
#33
JOURNAL ARTICLE
Rishi Rikhi, Christopher L Schaich, George W Hafzalla, Nisha A Patel, Jordan E Tannenbaum, Charles A German, Tamar Polonsky, Michael Y Tsai, Muhammad I Ahmad, Tareq Islam, Parag A Chevli, Michael D Shapiro
AIM: Elevated small dense-LDL-cholesterol (sd-LDL-C) increases atherosclerotic cardiovascular disease (CVD) risk. Although coronary artery calcium (CAC) is widely used for predicting CVD events, few studies have examined the relationship between sd-LDL-C and CAC. METHODS: This study included 4672 individuals with directly-measured baseline sd-LDL-C and CAC from the Multi-Ethnic Study of Atherosclerosis (mean [SD] age: 61.9 [10.4] years; 52.5% women; 47.3% with baseline CAC [mean score >0])...
February 7, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38309426/association-between-statin-use-and-incident-pad-according-to-race-age-and-presence-of-depression-in-the-multi-ethnic-study-of-atherosclerosis-mesa
#34
JOURNAL ARTICLE
Demetria M Bolden, Adane F Wogu, Pamela N Peterson, Elsie G Ross, Shea E Hogan, Kunihiro Matsushita, Michael H Criqui, Matthew Allison
BACKGROUND: Peripheral artery disease (PAD) is associated with high morbidity and mortality and has been commonly described as a coronary heart disease equivalent. Statin medications are recommended for primary prevention of atherosclerotic cardiovascular disease (ASCVD) among other indications. Therefore, understanding the longitudinal relationship of incident PAD is necessary to inform future research on how to prevent disease. Depression complicates cardiovascular disease (CVD) patients' ability to properly adhere to their medications, yet the effect of depression on the relationship between statin use and incident PAD is understudied...
February 1, 2024: Annals of Vascular Surgery
https://read.qxmd.com/read/38305253/milvexian-a-focus-on-a-new-oral-anticoagulant-that-targets-factor-xia-for-thromboembolism-prophylaxis
#35
JOURNAL ARTICLE
Joseph Birchansky, William H Frishman
Drugs that target factor XI and/or XIa have been evaluated as alternatives to existing anticoagulants, in light of studies that indicate that a decrease in Factor XI/XIa levels or activity may result in a lower risk of thrombosis without a significant increase in bleeding risk. Milvexian is an investigational small-molecule factor XIa inhibitor that has recently completed phase 2 clinical trials. Preclinical studies were suggestive of its potential to prevent arterial and venous thrombosis. It was well-tolerated in healthy participants, as well as in participants with mild or moderate hepatic impairment and moderate or severe renal impairment...
February 2, 2024: Cardiology in Review
https://read.qxmd.com/read/38300625/the-association-of-lipoprotein-a-and-coronary-artery-calcium-in-asymptomatic-patients-a-systematic-review-and-meta-analysis
#36
JOURNAL ARTICLE
Felipe Villa Martignoni, José Eduardo, Isabela R Marques, Cintia Gomes, Vittoria Caporal S Moreira, Isabela Af de Souza, Isabele A Miyawaki, Caroliny H Silva, Augusto Barreto do Amaral Neto, Eduardo Mh Padrão, Rhanderson Cardoso, Henrique Doria de Vasconcellos, Michael Miedema
AIMS: Lipoprotein(a) [Lp(a)] is an atherogenic lipid particle associated with increased risk for coronary heart disease (CHD) events. Coronary artery calcium (CAC) score is a tool to diagnose subclinical atherosclerosis and guide clinical decision-making for primary prevention of CHD. Studies show conflicting results concerning the relationship between Lp(a) and CAC in asymptomatic populations. We conducted a meta-analysis to evaluate the association of Lp(a) and CAC in asymptomatic patients...
February 1, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38295661/qihuang-zhuyu-formula-alleviates-coronary-microthrombosis-by-inhibiting-pi3k-akt-%C3%AE-iib%C3%AE-3-mediated-platelet-activation
#37
JOURNAL ARTICLE
Yuhan Ding, Qian Xiang, Peiyuan Zhu, Manlu Fan, Huaqin Tong, Mengxi Wang, Songyi Cheng, Peng Yu, Haibo Shi, Haowen Zhang, Xiaohu Chen
BACKGROUND: Coronary microembolism (CME) is commonly seen in the peri-procedural period of Percutaneous Coronary Intervention (PCI), where local platelet activation and endothelial cell inflammation crosstalk may lead to micro thrombus erosion and rupture, with serious consequences. Qihuang Zhuyu Formula (QHZYF) is a Chinese herbal compound with high efficacy against coronary artery disease, but its antiplatelet mechanism is unclear. HYPOTHESIS/PURPOSE: This study aimed to elucidate the effects and mechanisms of QHZYF on sodium laurate-induced CME using network pharmacology and in vitro and in vivo experiments...
December 14, 2023: Phytomedicine
https://read.qxmd.com/read/38290442/correlation-between-intracoronary-vascular-ultrasound-indexes-in-patients-with-coronary-heart-disease
#38
JOURNAL ARTICLE
Pengxiang Zhang, Rui Wang, Aiai Zhang, Feixing Li, Xiaoning Li, Weiguang Chen, Huixian Li, Zhuoran Li, Fangjiang Li
BACKGROUND: Coronary atherosclerosis is a serious and progressive condition characterized by the accumulation of plaques, consisting of fat, cholesterol, and other substances, within the arteries that supply blood to the heart. These plaques can harden and narrow the arteries, leading to reduced blood flow to the heart muscle. OBJECTIVE: The primary objective of this study is to investigate the correlation between specific cardiovascular parameters and intracoronary vascular ultrasound indexes in patients diagnosed with coronary heart disease...
January 1, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38268305/comparing-the-association-of-two-metabolic-syndrome-definitions-ncep-atp-iii-and-idf-with-the-risk-of-developing-atherosclerotic-cardiovascular-disease-an-analytical-cross-sectional-study
#39
JOURNAL ARTICLE
Gholamreza Yousefzadeh, Amin Sayyadi, Hamid Najafipour, Vida Sabaghnejad, Sara Pezeshki
INTRODUCTION: Atherosclerotic cardiovascular diseases (ASCVD) are significant sources of mortality and morbidity with substantial economic implications and preventive measures play key roles in this regard. Metabolic syndrome (MetS) is a common condition, and its association with ASCVD and mortality has made it clinically important. However, controversies persist regarding the best definition for MetS. Here in, we investigated the ability of the International Diabetes Federation (IDF) and the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) in the prediction of ASCVD incidence...
January 2024: Endocrinology, Diabetes & Metabolism
https://read.qxmd.com/read/38267238/multicentre-open-label-randomised-controlled-trial-to-compare-early-intervention-with-calcimimetics-and-conventional-therapy-in-preventing-coronary-artery-calcification-in-patients-with-secondary-hyperparathyroidism-upcoming-a-study-protocol
#40
JOURNAL ARTICLE
Daijo Inaguma, Yoshitaka Tatematsu, Naoki Okamoto, Soshiro Ogata, Hideki Kawai, Eiichi Watanabe, Yukio Yuzawa, Midori Hasegawa, Naotake Tsuboi
INTRODUCTION: Coronary artery and heart valve calcification is a risk factor for cardiovascular death in haemodialysis patients, so calcification prevention should be started as early as possible. Treatment with concomitant calcimimetics and low-dose vitamin D receptor activators (VDRAs) is available, but not enough evidence has been obtained on the efficacy of this regimen, particularly in patients with short dialysis duration. Therefore, this study will evaluate the efficacy and safety of early intervention with upacicalcet, a calcimimetic used to prevent coronary artery calcification in this patient population...
January 24, 2024: BMJ Open
keyword
keyword
54347
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.