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https://www.readbyqxmd.com/read/29775233/dialysis-modality-and-mortality-in-polycystic-kidney-disease
#1
Chenchen Zhou, Yaodong Gu, Changlin Mei, Bing Dai, Yi Wang, Cheng Xue
INTRODUCTION: Identifying the appropriate modality between hemodialysis (HD) and peritoneal dialysis (PD) is an unresolved issue in polycystic kidney disease (PKD) patients. This study aims to illustrate whether the mortality and survival are different among individuals receiving HD comparing PD. METHODS: We searched PubMed, EMBASE, and China National Knowledge Infrastructure about cohort studies involving PKD patients with end stage renal disease and comparing HD with PD...
May 18, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29767390/safety-and-efficacy-of-endoscopic-retrograde-cholangiopancreatography-for-choledocholithiasis-in-long-term-dialysis-a-propensity-score-analysis
#2
Sung Bum Kim, Kook Hyun Kim, Tae Nyeun Kim
BACKGROUND AND AIM: Previous studies evaluating the safety of endoscopic retrograde cholangiopancreatography (ERCP) in patients with end-stage renal disease (ESRD) undergoing hemodialysis reported an increased risk of post-procedural bleeding. We investigated the safety and efficacy of ERCP for the treatment of choledocholithiasis in patients with ESRD undergoing long-term dialysis. METHODS: A total of 3466 patients who underwent ERCP due to choledocholithiasis between January 2000 and Feb 2018 were reviewed and analyzed retrospectively...
May 16, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29746497/peritoneal-dialysis-related-peritonitis-caused-by-pseudomonas-species-insight-from-a-post-millennial-case-series
#3
Wanhong Lu, Bonnie Ching-Ha Kwan, Kai Ming Chow, Wing-Fai Pang, Chi Bon Leung, Philip Kam-To Li, Cheuk Chun Szeto
BACKGROUND: Pseudomonas peritonitis is a serious complication of peritoneal dialysis (PD). However, the clinical course of Pseudomonas peritonitis following the adoption of international guidelines remains unclear. METHODS: We reviewed the clinical course and treatment response of 153 consecutive episodes of PD peritonitis caused by Pseudomonas species from 2001 to 2015. RESULTS: Pseudomonas peritonitis accounted for 8.3% of all peritonitis episodes...
2018: PloS One
https://www.readbyqxmd.com/read/29735820/-fusarium-the-versatile-pathogen
#4
REVIEW
Ananya Tupaki-Sreepurna, Anupma Jyoti Kindo
Fusarium is an emerging human opportunistic pathogen of growing importance, especially among immunosuppressed haematology patients due to an increased incidence of disseminated infections over the past two decades. This trend is expected only to continue due to the advances in medical and surgical technologies that will prolong the lives of the severely ill, making these patients susceptible to rare opportunistic infections. Production of mycotoxins, enzymes such as proteases, angio-invasive property and an intrinsically resistant nature, makes this genus very difficult to treat...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29686909/spontaneous-bacterial-peritonitis-due-to-lactobacillus-paracasei-in-cirrhosis
#5
Emily Harding-Theobald, Bharat Maraj
Lactobacillus species colonize the human gastrointestinal tract and are rarely pathogenic. We present a case involving a cirrhotic patient who presented with sepsis and was found to have peritoneal cultures demonstrating Lactobacillus as the sole pathogen concerning for spontaneous bacterial peritonitis. Treatment was achieved with high-dose penicillin and clindamycin but the patient developed hepatorenal syndrome and died from acute renal failure. Intra-abdominal Lactobacillus infections are typically seen in patients undergoing peritoneal dialysis or who have recently had bowel perforation...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29685985/-b-orrelia-host-ad-aptation-p-rotein-badp-is-required-for-the-colonization-of-a-mammalian-host-by-the-agent-of-lyme-disease
#6
Trever C Smith, Sarah M Helm, Yue Chen, Ying-Han Lin, S L Rajasekhar Karna, J Seshu
Borrelia burgdorferi ( Bb ), the agent of Lyme disease (LD), uses host-derived signals to modulate gene expression during the vector and mammalian phases of infection. Microarray analysis of mutants lacking <u>B</u>orrelia host-<u>ad</u>aptation <u>R</u>egulator (BadR) revealed down-regulation of genes encoding enzymes whose role in the patho-physiology of Bb is unknown. Immunoblot analysis of the badR mutants confirmed reduced levels of these enzymes and one of these enzymes encoded by bb0086 , shares homology to prokaryotic magnesium chelatase and Lon-type proteases...
April 23, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29683218/-outcome-of-patients-with-hemodialysis-or-peritoneal-dialysis-undergoing-simultaneous-pancreas-kidney-transplantation-comparative-study
#7
Alberto Marcacuzco, Carlos Jiménez-Romero, Alejandro Manrique, Jorge Calvo, Félix Cambra, Óscar Caso, Álvaro García-Sesma, Anisa Nutu, Iago Justo
BACKGROUND: Controversy remains with regard to the higher risk of intraabdominal infections and lower patient and graft survival when peritoneal dialysis (PD) rather than hemodialysis (HD) is used in simultaneous pancreas-kidney transplantation (SPKT). METHODS: From March 1995 to December 2015 we performed 165 SPKTs. Prior to transplant, patients received hemodialysis (Group HD; n=98) or peritoneal dialysis (Group PD; n=67). A comparison was performed to analyze posttransplant complications and patient, pancreas and kidney graft survivals...
April 23, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29679398/application-of-instant-messaging-software-in-the-follow-up-of-patients-using-peritoneal-dialysis-a-randomized-controlled-trial
#8
Fang Cao, Lanfei Li, Miao Lin, Qinyu Lin, Yiping Ruan, Fuyuan Hong
AIMS AND OBJECTIVES: This study aims to investigate the application value of Internet-based instant messaging software in the follow-up of patients using peritoneal dialysis(PD). BACKGROUND: PD is an effective renal replacement treatment for end-stage renal disease. The clinical usefulness of Internet-based instant messaging software in the follow-up of PD patients, including the incidence of peritonitis and exit-site infection, the levels of albumin and electrolytes and the degree of patients' satisfaction, remains unknown...
April 20, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29666088/transection-versus-infection-acute-appendicitis-in-a-peritoneal-dialysis-patient-presenting-as-catheter-dysfunction-and-discontinuity-on-x-ray
#9
Tatiana Thom, Deanne Leonard, Peter Fitzpatrick, Nabeel Aslam
Acute appendicitis in peritoneal dialysis patients generally presents as abdominal pain and cloudy dialysate. We report a case of acute appendicitis in a peritoneal dialysis patient that presented as poor dialysate fluid drainage and an abnormal abdominal X-ray showing breakage in the continuity of the catheter. Catheter dysfunction in this case was caused by acute appendicitis leading to the formation of adhesions with peritoneal dialysis catheter trapped in it. This resulted in radiological appearance of catheter breakage, although catheter itself was intact...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29663590/use-of-deferasirox-exjade-for-iron-overload-in-peritoneal-dialysis-patients
#10
Erwin Yii, James Cg Doery, Zane Kaplan, Peter G Kerr
BACKGROUND: A 54 year old male with β-Thalassemia major developed ESRD and was managed with continuous ambulatory peritoneal dialysis. Although not able to be transfused due to high titre red cell antibodies he did require management of iron overload. Deferasirox (Exjade) was administered orally. There was concern that excretion of iron via the peritoneal dialysate may raise the risk of iron-dependent infections (Yersinia and Rhizopus). METHODS: Whilst receiving Exjade 1000mg /day, a total collection of 12...
April 16, 2018: Nephrology
https://www.readbyqxmd.com/read/29657222/management-of-salmonella-peritonitis-in-a-patient-on-peritoneal-dialysis-without-catheter-removal
#11
Firas Fahad Al-Zahrani, Hussain Al-Shahrani, Ashwaq Al-Mohawes, Abdullah Al-Hwiesh, Abdusalam Noor, Ibrahiem Saeed Abdulrahmn
Peritoneal dialysis (PD)-associated peritonitis is an important contributor to morbidity and mortality; Gram-positive bacteria constitute the most frequent associated pathogens (45%-60%) followed by Gram-negative bacteria (25%-40%) and fungal infection (3%-6%). Salmonella peritonitis is an extremely rare cause of peritonitis (0.15%). Peritonitis attributed to Salmonella has been reported only in four cases. Herewith, we report a 68-year-old Sudanese female who presented to our PD unit with abdominal pain and diarrhea and was diagnosed to have Salmonella peritonitis...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29655573/-the-reality-on-peritoneal-dialysis-in-france-40years-after
#12
Jacques Rottembourg, Guy Rostoker
The share of peritoneal dialysis (PD) in the spectrum of chronic dialysis has decreased in France over the last ten years. Despite various facilities offered by the health authorities, PD remains confidential in many private units and some public hospitals. The enthusiasm present at the beginning of this technology, forty years ago, is declining, despite a real improvement in new developments, a real increase in patient survival, today at least similar to that on hemodialysis. Then, the aim of this review is first to give a summary of the principles and practice of patient and staff education and to describe the role of the medical contribution in decision-making...
April 11, 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29644070/intravenous-drug-users-who-require-dialysis-causes-of-renal-failure-and-outcomes
#13
Jemima K Scott, Dominic M Taylor, Chris R K Dudley
Background: Intravenous drug use is associated with progressive kidney disease of several aetiologies. It is associated with behavioural and lifestyle characteristics that make the provision of renal replacement therapies (RRTs) challenging. We observed that patients who use intravenous drugs [people who inject drugs (PWID)] present late to renal services and struggle to engage with treatment. We describe the experience of a UK centre providing renal services to a mixed city and rural population...
April 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29616470/peritoneal-dialysis-as-initial-dialysis-modality-a-viable-option-for-late-presenting-end-stage-renal-disease
#14
REVIEW
Muhammad Masoom Javaid, Behram Ali Khan, Srinivas Subramanian
Late-presenting end-stage renal disease is a significant problem worldwide. Up to 70% of patients start dialysis in an unplanned manner without a definitive dialysis access in place. Haemodialysis via a central venous catheter is the default modality for the majority of such patients, and peritoneal dialysis is usually not considered as a feasible option. However, in the recent years, some reports on urgent-start peritoneal dialysis in the late-presenting end-stage renal disease have been published. The collective experience shows that PD can be a safe, efficient and cost-effective alternative to haemodialysis in late-presenting end-stage renal disease with comparable outcomes to the conventional peritoneal dialysis and urgent-start haemodialysis...
April 3, 2018: Journal of Nephrology
https://www.readbyqxmd.com/read/29611117/intestinal-perforation-by-a-peritoneal-dialysis-catheter-in-which-fungal-peritonitis-led-to-diagnosis-a-rare-case-report
#15
Hisato Shima, Shogo Mizoguchi, Yuji Morine, Manabu Tashiro, Kazuyoshi Okada, Jun Minakuchi, Shu Kawashima
Intestinal perforation by a peritoneal catheter is an uncommon, but serious, complication that has a high mortality rate. Intestinal perforation in peritoneal dialysis (PD) patients is difficult to diagnose using symptoms and radiological findings, which may result in a delay in diagnosis. Moreover, intestinal perforation complicated with fungal peritonitis is reportedly a severe condition with a poor prognosis. Herein, we report the case of a 78-year-old man on PD, whose diagnosis of perforative peritonitis was difficult to diagnose preoperatively...
April 2, 2018: CEN Case Reports
https://www.readbyqxmd.com/read/29594145/exit-site-infection-due-to-mycobacterium-chelonae-in-an-elderly-patient-on-peritoneal-dialysis
#16
Arata Hibi, Takahisa Kasugai, Keisuke Kamiya, Chiharu Ito, Satoru Kominato, Toshiyuki Miura, Katsushi Koyama
Nontuberculous mycobacteria (NTM) are rarely isolated from peritoneal dialysis (PD)-associated catheter infections. However, NTM infection is usually difficult to treat and leads to catheter loss. Prompt diagnosis is essential for appropriate treatment. A 70-year-old Japanese man who had been on PD for 2 years and with a medical history of 2 episodes of exit site infections (ESIs) due to methicillin-resistant Staphylococcus aureus was admitted to the hospital due to suspected ESI recurrence. However, Gram staining of the pus revealed no gram-positive cocci...
January 2018: Case Reports in Nephrology and Dialysis
https://www.readbyqxmd.com/read/29591533/peritoneal-dialysis-catheter-insertion-surgery-and-management
#17
Kazunari Yoshida, Daisuke Ishii
Peritoneal access surgery is the first step to achieve successful peritoneal dialysis. It is important to perform easy, safe, and less invasive surgery of peritoneal dialysis catheter insertion. Secure peritoneal dialysis catheter insertion will lead to less infection, that is, exit site, tunnel infection, and peritonitis, which sometimes result in peritoneal dialysis discontinuation. To avoid these undesirable results, we should perform good and proper peritoneal dialysis insertion surgery. In this article, we describe peritoneal dialysis catheter insertion surgery and its management...
March 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29563773/development-of-controlled-release-silicone-adhesive-based-mupirocin-patch-demonstrates-antibacterial-activity-on-live-rat-skin-against-staphylococcus-aureus
#18
Sheba R David, Nurafiqah Malek, Abdul Hanif Mahadi, Srikumar Chakravarthi, Rajan Rajabalaya
Background: Peritonitis is the most serious complication of peritoneal dialysis. Staphylococcus aureus infections could lead to peritonitis which causes reversal of peritoneal dialysis treatment back to hemodialysis. The aim of this study was to develop a controlled release silicone adhesive-based mupirocin patch for prophylactic effect and analyze its antibacterial effectiveness against S. aureus . Methods: The matrix patches were prepared by using different polymers, with and without silicone adhesive, dibutyl sebacate and mupirocin...
2018: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29563276/non-tuberculous-mycobacterial-infections-related-to-peritoneal-dialysis
#19
Hiroyuki Inoue, Naoki Washida, Kohkichi Morimoto, Keisuke Shinozuka, Takahiro Kasai, Kiyotaka Uchiyama, Hirobumi Tokuyama, Shu Wakino, Hiroshi Itoh
Most infections related to peritoneal dialysis (PD) are caused by common bacteria, and non-tuberculous mycobacteria are rare. The clinical characteristics and prognosis of PD patients with non-tuberculous mycobacterial infections were investigated at our hospital. Non-tuberculous mycobacteria were detected in 11 patients (exit-site infection, tunnel infection, and peritonitis in 3, 5, and 3 patients, respectively). Mycobacterium fortuitum , Mycobacterium chelonae , and Mycobacterium abscessus were identified in 4, 2, and 2 patients, respectively...
March 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29529965/after-peritoneal-dialysis-discontinuation-when-will-we-remove-peritoneal-dialysis-catheter
#20
Hirotake Kasuga
Most of the peritoneal dialysis patients stop their peritoneal dialysis therapy and transfer to hemodialysis or kidney transplantation. In Japan, most end-stage kidney disease patients select hemodialysis after peritoneal dialysis discontinuation. Peritoneal dialysis catheter will be removed after stopping peritoneal dialysis. If peritoneal dialysis patients suffer from refractory peritonitis or severe tunnel infection, we remove the peritoneal dialysis catheter immediately. However, the causes of peritoneal dialysis discontinuation are ultrafiltration failure or peritoneal membrane dysfunction, and we have to consider the timing of peritoneal dialysis catheter removal...
March 1, 2018: Journal of Vascular Access
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