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https://www.readbyqxmd.com/read/28449500/resectable-primary-pleural-myxoid-liposarcoma-with-a-pedicle-report-of-a-rare-case-and-literature-review
#1
Fang Wang, Shigeru Kiryu, Li Li, Qing Wang, Dumin Li, Lifeng Zhang
Primary pleural myxoid liposarcoma is a rare tumor. Here, we report a primary myxoid liposarcoma occupying the majority of the left thoracic cavity with features suggesting invasion. Computed tomography (CT) at medical check-up incidentally revealed a bulky inhomogeneous fatty mass. The tumor's large size made a prediction of its resectability by preoperative CT difficult. The patient underwent an operation, which revealed that the tumor was attached to the pleura with a thin pedicle; the tumor was resected completely...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449234/magnetic-resonance-imaging-and-computed-tomographic-characteristics-of-a-glioma-causing-calvarial-erosion-in-a-dog
#2
Alfredo Recio, Cristian de la Fuente, Martí Pumarola, Yvonne Espada, Sònia Añor
An 8-year-old female Boxer was examined for acute onset of seizures. On magnetic resonance imaging (MRI), an intra-axial mass with imaging features consistent with glioma was observed in the right cerebral hemisphere. A defect in the temporal bone adjacent to the mass was observed. Postmortem computed tomography (CT) confirmed temporal bone osteolysis and necropsy demonstrated a glioblastoma with associated calvarial erosion. Although occasionally described in human medicine, to our knowledge, this is the first description of a brain glioma causing calvarial erosion in a dog...
April 27, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28448956/concentration-dependent-switch-in-the-kinetic-pathway-of-lysozyme-fibrillation-spectroscopic-and-microscopic-analysis
#3
E Kiran Kumar, Deepak Kumar Prasad, N Prakash Prabhu
Formation of amyloid fibrils is found to be a general tendency of many proteins. Investigating the kinetic mechanisms and structural features of the intermediates and the final fibrillar state is essential to understand their role in amyloid diseases. Lysozyme, a notable model protein for amyloidogenic studies, readily formed fibrils in vitro at neutral pH in the presence of urea. It, however, showed two different kinetic pathways under varying urea concentrations when probed with thioflavin T (ThT) fluorescence...
April 17, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28448836/breast-cancer-detection-in-automated-3d-breast-ultrasound-using-iso-contours-and-cascaded-rusboosts
#4
Ehsan Kozegar, Mohsen Soryani, Hamid Behnam, Masoumeh Salamati, Tao Tan
Automated 3D breast ultrasound (ABUS) is a new popular modality as an adjunct to mammography for detecting cancers in women with dense breasts. In this paper, a multi-stage computer aided detection system is proposed to detect cancers in ABUS images. In the first step, an efficient despeckling method called OBNLM is applied on the images to reduce speckle noise. Afterwards, a new algorithm based on isocontours is applied to detect initial candidates as the boundary of masses is hypo echoic. To reduce false generated isocontours, features such as hypoechoicity, roundness, area and contour strength are used...
April 20, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28448667/association-between-facial-rejuvenation-and-observer-ratings-of-youth-attractiveness-success-and-health
#5
Kristin L Bater, Lisa E Ishii, Ira D Papel, Theda C Kontis, Patrick J Byrne, Kofi D O Boahene, Jason C Nellis, Masaru Ishii
Importance: Surgical procedures for the aging face-including face-lift, blepharoplasty, and brow-lift-consistently rank among the most popular cosmetic services sought by patients. Although these surgical procedures are broadly classified as procedures that restore a youthful appearance, they may improve societal perceptions of attractiveness, success, and health, conferring an even larger social benefit than just restoring a youthful appearance to the face. Objectives: To determine if face-lift and upper facial rejuvenation surgery improve observer ratings of age, attractiveness, success, and health and to quantify the effect of facial rejuvenation surgery on each individual domain...
April 27, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28448415/investigation-on-computed-tomography-features-of-primary-thymic-atypical-carcinoid-tumors
#6
Xiaojing Kan, Pengming Wang, Zhiquan Gong, Feifei Gao, Yuxia Zhang, Yinghui Ge
OBJECTIVES: The thymic atypical carcinoid tumors (aTCs) are rare. The computed tomography (CT) features of aTC were poorly studied, and researches under this topic with large samples are in a small quantity in the literature. Our aim was to investigate the CT features of aTC. METHODS: Eleven cases of aTC (7 men and 4 women; mean age, 56 ± 16 years) proved by pathology were retrospectively analyzed. All the patients underwent contrast-enhanced CT scans with dual phase (25-30 and 60-70 seconds) after contrast agent injection...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448414/computed-tomography-features-of-benign-and-malignant-calcified-thyroid-nodules-a-single-center-study
#7
Donghyun Kim, Dong Wook Kim, Young Jin Heo, Jin Wook Baek, Yoo Jin Lee, Young Mi Park, Hye Jin Baek, Soo Jin Jung
OBJECTIVE: No previous studies have investigated thyroid calcification on computed tomography (CT) quantitatively by using Hounsfield unit (HU) values. This study aimed to analyze quantitative HU values of thyroid calcification on preoperative neck CT and to assess the characteristics of benign and malignant calcified thyroid nodules (CTNs). MATERIALS AND METHODS: Two hundred twenty patients who underwent neck CT before thyroid surgery from January 2015 to June 2016 were included...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448235/intracranial-artery-steno-occlusion-diagnosis-by-using-three-dimensional-parallel-multichannel-transmission-mr-imaging
#8
Mi Sun Chung, Seung Chai Jung, Seon-Ok Kim, Ho Sung Kim, Choong Gon Choi, Sang Joon Kim, Sun U Kwon, Dong-Wha Kang, Jong S Kim
Purpose To determine whether magnetic resonance (MR) imaging by using two-dimensional spatially selective radiofrequency (RF) excitation pulses (zoomed MR imaging) is a reliable method for the diagnosis of intracranial artery steno-occlusion compared with full-field-of-view (FOV) MR imaging. Materials and Methods The institutional review board approved this retrospective study and informed consent was waived. From December 2014 to August 2015, 88 patients who underwent both full-FOV MR imaging and zoomed MR imaging for further evaluation of intracranial artery steno-occlusion at prior luminal evaluation were included...
April 27, 2017: Radiology
https://www.readbyqxmd.com/read/28448040/determination-of-high-affinity-antibody-antigen-binding-kinetics-using-four-biosensor-platforms
#9
Danlin Yang, Ajit Singh, Helen Wu, Rachel Kroe-Barrett
Label-free optical biosensors are powerful tools in drug discovery for the characterization of biomolecular interactions. In this study, we describe the use of four routinely used biosensor platforms in our laboratory to evaluate the binding affinity and kinetics of ten high-affinity monoclonal antibodies (mAbs) against human proprotein convertase subtilisin kexin type 9 (PCSK9). While both Biacore T100 and ProteOn XPR36 are derived from the well-established Surface Plasmon Resonance (SPR) technology, the former has four flow cells connected by serial flow configuration, whereas the latter presents 36 reaction spots in parallel through an improvised 6 x 6 crisscross microfluidic channel configuration...
April 17, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28448005/open-source-single-particle-analysis-for-super-resolution-microscopy-with-virusmapper
#10
Robert D M Gray, Jason Mercer, Ricardo Henriques
Super-resolution fluorescence microscopy is currently revolutionizing cell biology research. Its capacity to break the resolution limit of around 300 nm allows for the routine imaging of nanoscale biological complexes and processes. This increase in resolution also means that methods popular in electron microscopy, such as single-particle analysis, can readily be applied to super-resolution fluorescence microscopy. By combining this analytical approach with super-resolution optical imaging, it becomes possible to take advantage of the molecule-specific labeling capacity of fluorescence microscopy to generate structural maps of molecular elements within a metastable structure...
April 9, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28447767/biopsy-versus-resection-for-the-management-of-low-grade-gliomas
#11
REVIEW
Bowen Jiang, Kaisorn Chaichana, Anand Veeravagu, Steven D Chang, Keith L Black, Chirag G Patil
BACKGROUND: This is an updated version of the original Cochrane review published in 2013, Issue 4.Low-grade gliomas (LGG) constitute a class of slow-growing primary brain neoplasms. Patients with clinically and radiographically suspected LGG have two initial surgical options, biopsy or resection. Biopsy can provide a histological diagnosis with minimal risk but does not offer a direct treatment. Resection may have additional benefits such as increasing survival and delaying recurrence, but is associated with a higher risk for surgical morbidity...
April 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28447493/m2-segment-dissection-of-middle-cerebral-artery-diagnosed-using-high-resolution-magnetic-resonance-imaging
#12
Xiaoyan Song, Haiyan Lv, Jianjun Tang, Qing Zhang, Qiaoshu Wang
Middle cerebral artery (MCA) dissection is a rare cause of ischemic stroke, especially in the M2 or M3 segments. Diagnosis of intracranial artery dissection remains challenging. We herein report a case of M2 segment dissection of the MCA with typical features of an intimal flap and intramural hematoma diagnosed using high-resolution 3T magnetic resonance imaging. This imaging technique might be a more effective noninvasive method by which to diagnose M2 segment dissection of the MCA than either computed tomography angiography or digital subtraction angiography...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28447352/dermoscopic-evaluation-of-melanonychia
#13
REVIEW
Hiroshi Koga
The prevalence of melanonychia is approximately 1%, and it is a common symptom encountered in daily practise. However, it may also be the first symptom of melanoma of the nail apparatus. Evaluation of adult melanonychia with clinical information and clinical images is sometimes difficult for clinicians. Dermoscopic observation provides important information based on the algorithm method. Melanonychia in children requires a different approach, because dermoscopic features observed in adult nail apparatus melanoma are generally observed in benign pediatric cases...
May 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28447308/determinants-of-stage-at-diagnosis-of-breast-cancer-in-nigerian-women-sociodemographic-breast-cancer-awareness-health-care-access-and-clinical-factors
#14
Elima Jedy-Agba, Valerie McCormack, Oluwole Olaomi, Wunmi Badejo, Monday Yilkudi, Terna Yawe, Emmanuel Ezeome, Iliya Salu, Elijah Miner, Ikechukwu Anosike, Sally N Adebamowo, Benjamin Achusi, Isabel Dos-Santos-Silva, Clement Adebamowo
PURPOSE: Advanced stage at diagnosis is a common feature of breast cancer in Sub-Saharan Africa (SSA), contributing to poor survival rates. Understanding its determinants is key to preventing deaths from this cancer in SSA. METHODS: Within the Nigerian Integrative Epidemiology of Breast Cancer Study, a multicentred case-control study on breast cancer, we studied factors affecting stage at diagnosis of cases, i.e. women diagnosed with histologically confirmed invasive breast cancer between January 2014 and July 2016 at six secondary and tertiary hospitals in Nigeria...
April 26, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28447220/track-weighted-dynamic-functional-connectivity-tw-dfc-a-new-method-to-study-time-resolved-functional-connectivity
#15
Fernando Calamante, Robert E Smith, Xiaoyun Liang, Andrew Zalesky, Alan Connelly
Interest in the study of brain connectivity is growing, particularly in understanding the dynamics of the structural/functional connectivity relation. Structural and functional connectivity are most often analysed independently of each other. Track-weighted functional connectivity (TW-FC) was recently proposed as a means to combine structural/functional connectivity information into a single image. We extend here TW-FC in two important ways: first, all the functional data are used without having to define a prior functional network (cf...
April 26, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28447208/squamous-cell-carcinoma-of-the-lung-associated-with-anti-jo1-antisynthetase-syndrome-a-case-report-and-review-of-the-literature
#16
REVIEW
G Boleto, J-M Perotin, J-P Eschard, J-H Salmon
Antisynthetase syndrome is a heterogeneous idiopathic inflammatory myopathy. Anti-Jo1 is the most common antibody found in this condition. Dermatomyositis is known to be associated with malignancy, but the association between antisynthetase syndrome and malignancy is not clearly established. We report a case of an association of squamous cell carcinoma of the lung and anti-Jo1 antisynthetase syndrome. A 67-year-old man presented with polyarthritis, muscle weakness of the pelvic girdle, "mechanic's hands," and weight loss...
April 26, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28447112/-imaging-diagnostics-of-breast-metastases-from-extramammary-tumors
#17
REVIEW
S Wienbeck, S Nemat, J Lotz, A Surov
Breast metastases of solid extramammary tumors are very rare in comparison to primary malignancies of the breast and account for only 0.33-6.3% of all malignant neoplasms of the breast. The most common primary tumors are malignant melanoma, distant sarcomas, lung cancer, ovarian cancer, renal cell cancer and thyroid cancer in decreasing order of frequency. This review article summarizes the clinical features and the different imaging findings of breast metastases from different extramammary solid tumors. Breast metastases are often incidental findings in computed tomography (CT) or positron emission tomography CT (PET-CT) imaging...
April 26, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28447085/studying-structure-and-dynamics-of-self-assembled-peptide-nanostructures-using-fluorescence-and-super-resolution-microscopy
#18
Sílvia Pujals, Kai Tao, Adrià Terradellas, Ehud Gazit, Lorenzo Albertazzi
Understanding the formation and properties of self-assembled peptide nanostructures is the basis for the design of new architectures for various applications. Here we show the potential of fluorescence and super resolution imaging to unveil the structural and dynamic features of peptide nanofibers with high spatiotemporal resolution.
April 27, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28446490/complicated-acute-cerebellitis-with-obstructive-hydrocephalus-and-tonsillar-herniation-in-a-child
#19
Manchikanti Venkatesh, Sunitha Vellathussery Chakkalakkoombil, Manju Bashini Duraipandi, Reena Gulati
Acute cerebellitis (AC) is a rare inflammatory syndrome presenting as cerebellar dysfunction, seen more frequently in children. AC can have a variable course with features of cerebellar dysfunction, raised intracranial pressure and neurological deficits, and can sometimes even be potentially fatal due to complications such as obstructive hydrocephalus and brainstem compression, warranting surgical intervention. We report a case of a 12-year-old boy who presented with raised intracranial pressure and ataxia...
April 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28445774/voxresnet-deep-voxelwise-residual-networks-for-brain-segmentation-from-3d-mr-images
#20
REVIEW
Hao Chen, Qi Dou, Lequan Yu, Jing Qin, Pheng-Ann Heng
Segmentation of key brain tissues from 3D medical images is of great significance for brain disease diagnosis, progression assessment and monitoring of neurologic conditions. While manual segmentation is time-consuming, laborious, and subjective, automated segmentation is quite challenging due to the complicated anatomical environment of brain and the large variations of brain tissues. We propose a novel voxelwise residual network (VoxResNet) with a set of effective training schemes to cope with this challenging problem...
April 23, 2017: NeuroImage
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