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Pediatric chronic pain

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https://www.readbyqxmd.com/read/28486647/clinical-and-economic-long-term-treatment-outcome-of-children-and-adolescents-with-disabling-chronic-pain
#1
Boris Zernikow, Ann-Kristin Ruhe, Lorin Stahlschmidt, Pia Schmidt, Tobias Staratzke, Michael Frosch, Julia Wager
Objective.:  Disabling pediatric chronic pain is accompanied by a significant burden to those affected and by high societal costs. Furthermore, it bears the risk of aggravation into adulthood. Studies have shown intensive interdisciplinary pain treatment to result in short-term positive effects on pain-related and psychological outcomes. In this study, we aimed to prove the stability of the long-term effects of intensive interdisciplinary pain treatment four years after treatment. Methods...
May 9, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28480554/vomiting-and-migraine-related-clinical-parameters-in-pediatric-migraine
#2
Tal Eidlitz-Markus, Yishai Haimi-Cohen, Avraham Zeharia
OBJECTIVE/BACKGROUND: To investigate the characteristics of vomiting in pediatric migraineurs and the relationship of vomiting with other migraine-related parameters. METHODS: The cohort included children and adolescents with migraine attending a headache clinic of a tertiary pediatric medical center from 2010 to 2016. Patients were identified by a retrospective database search. Data were collected from medical files. The presence of vomiting was associated with background and headache-related parameters...
May 7, 2017: Headache
https://www.readbyqxmd.com/read/28479208/sleep-quality-affect-pain-and-disability-in-children-with-chronic-pain-is-affect-a-mediator-or-moderator
#3
Subhadra Evans, Vesna Djilas, Laura C Seidman, Lonnie K Zeltzer, Jennie C I Tsao
Sleep problems have been identified as a potential antecedent of chronic pain and pain-related disability in pediatric populations. In adult studies, affect has been implicated in these relationships. This study sought to better understand the relationships between sleep quality, negative and positive affect and pain and functioning in children with chronic pain. Participants included 213 children and adolescents (aged 7-17) presenting to a tertiary pain clinic with chronic pain. Children completed questionnaires measuring sleep quality, positive and negative affect, pain intensity, and functional disability...
May 4, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28466453/hereditary-multiple-exostoses-new-insights-into-pathogenesis-clinical-complications-and-potential-treatments
#4
REVIEW
Maurizio Pacifici
PURPOSE OF REVIEW: Hereditary multiple exostoses (HME) is a complex musculoskeletal pediatric disorder characterized by osteochondromas that form next to the growth plates of many skeletal elements, including long bones, ribs, and vertebrae. Due to its intricacies and unresolved issues, HME continues to pose major challenges to both clinicians and biomedical researchers. The purpose of this review is to describe and analyze recent advances in this field and point to possible targets and strategies for future biologically based therapeutic intervention...
May 2, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28460714/core-outcome-sets-for-research-and-clinical-practice
#5
REVIEW
Alessandro Chiarotto, Raymond W Ostelo, Dennis C Turk, Rachelle Buchbinder, Maarten Boers
BACKGROUND: This masterclass introduces the topic of core outcome sets, describing rationale and methods for developing them, and providing some examples that are relevant for clinical research and practice. METHOD: A core outcome set is a minimum consensus-based set of outcomes that should be measured and reported in all clinical trials for a specific health condition and/or intervention. Issues surrounding outcome assessment, such as selective reporting and inconsistency across studies, can be addressed by the development of a core set...
March 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28460699/case-study-of-high-dose-ketamine-for-treatment-of-complex-regional-pain-syndrome-in-the-pediatric-intensive-care-unit
#6
REVIEW
Tracy Ann Pasek, Kelli Crowley, Catherine Campese, Rachel Lauer, Charles Yang
Complex regional pain syndrome (CRPS) is a life-altering and debilitating chronic pain condition. The authors are presenting a case study of a female who received high-dose ketamine for the management of her CRPS. The innovative treatment lies not only within the pharmacologic management of her pain, but also in the fact that she was the first patient to be admitted to our pediatric intensive care unit solely for pain control. The primary component of the pharmacotherapy treatment strategy plan was escalating-dose ketamine infusion via patient-controlled-analgesia approved by the pharmacy and therapeutics committee guided therapy for this patient...
June 2017: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/28445406/a-pilot-study-of-mindfulness-meditation-for-pediatric-chronic-pain
#7
Lynn C Waelde, Amanda B Feinstein, Rashmi Bhandari, Anya Griffin, Isabel A Yoon, Brenda Golianu
Despite advances in psychological interventions for pediatric chronic pain, there has been little research examining mindfulness meditation for these conditions. This study presents data from a pilot clinical trial of a six-week manualized mindfulness meditation intervention offered to 20 adolescents aged 13-17 years. Measures of pain intensity, functional disability, depression and parent worry about their child's pain were obtained at baseline and post-treatment. Results indicated no significant changes in pain or depression, however functional disability and frequency of pain functioning complaints improved with small effect sizes...
April 26, 2017: Children
https://www.readbyqxmd.com/read/28435316/subanesthetic-ketamine-for-pain-management-in-hospitalized-children-adolescents-and-young-adults-a-single-center-cohort-study
#8
Kathy A Sheehy, Caroline Lippold, Amy L Rice, Raissa Nobrega, Julia C Finkel, Zenaide Mn Quezado
BACKGROUND: Subanesthetic doses of ketamine, an N-methyl-d-aspartate receptor antagonist used as an adjuvant to opioid for the treatment of pain in adults with acute and chronic pain, have been shown, in some instances, to improve pain intensity and to decrease opioid intake. However, less is known about the role of ketamine in pain management in children, adolescents, and young adults. PURPOSE: We examined the effects of subanesthetic ketamine on pain intensity and opioid intake in children, adolescents, and young adults with acute and chronic pain syndromes treated in an inpatient setting...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28421117/chronic-pain-in-children-a-look-at-the-referral-process-to-a-pediatric-pain-clinic
#9
Giovanni Cucchiaro, Jennifer Schwartz, Alec Hutchason, Beatriz Ornelas
We reviewed the referral pattern of children with chronic pain to a specialized pediatric pain clinic. Data were obtained from referring physicians and medical records and during an interview with patients and their parents by physicians and a psychologist. We analyzed the following: referral diagnosis, demographics, duration of symptoms, number of physicians previously consulted, school attendance, sports activities, presence of psychological disorders, final team diagnosis, and outcomes. Children had been experiencing pain for 34 ± 55 months...
2017: International Journal of Pediatrics
https://www.readbyqxmd.com/read/28403504/extracorporeal-shock-wave-lithotripsy-is-safe-and-effective-for-pediatric-patients-with-chronic-pancreatitis
#10
Dan Wang, Ya-Wei Bi, Jun-Tao Ji, Lei Xin, Jun Pan, Zhuan Liao, Ting-Ting Du, Jin-Huan Lin, Di Zhang, Xiang-Peng Zeng, Bo Ye, Wen-Bin Zou, Hui Chen, Ting Xie, Bai-Rong Li, Zhao-Hong Zheng, Zhao-Shen Li, Liang-Hao Hu
Background and aims Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is recommended as the first-line treatment for pancreatic stones. However, how well P-ESWL performs in pediatric patients remains unclear. We aimed to evaluate the safety and efficacy of P-ESWL for pediatric patients with chronic pancreatitis. Methods This prospective observational study was conducted in patients with painful chronic pancreatitis who underwent P-ESWL. Patients aged under 18 years were included in the pediatric group; patients aged over 18 years who underwent P-ESWL in the same period were assigned to the control group...
May 2017: Endoscopy
https://www.readbyqxmd.com/read/28401741/oral-alendronate-in-pediatric-chronic-recurrent-multifocal-osteomyelitis
#11
Daishi Hirano, Kosuke Chiba, Saya Yamada, Hiroyuki Ida
Chronic recurrent multifocal osteomyelitis (CRMO) primarily affects children and adolescents, and is characterized by episodic sterile osteomyelitis over several years. No definitive treatment is available. Non-steroidal anti-inflammatory drugs (NSAID) are common first-line agents, but provide limited improvement in bone pain and do not affect disease duration. Several agents are utilized in the case of non-response to NSAID, including corticosteroids, methotrexate, and tumor necrosis factor-blocking agents...
April 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28394851/development-and-validation-of-the-self-reported-promis-pediatric-pain-behavior-item-bank-and-short-form-scale
#12
Natoshia R Cunningham, Susmita Kashikar-Zuck, Constance Mara, Kenneth R Goldschneider, Dennis A Revicki, Carlton Dampier, David D Sherry, Lori Crosby, Adam Carle, Karon F Cook, Esi M Morgan
Pain behaviors are important indicators of functioning in chronic pain; however, no self-reported pain behavior instrument has been developed for pediatric populations. The purpose of this study was to create a brief pediatric measure of patient-reported pain behaviors as part of the Patient- Reported Outcome Measurement Information System (PROMIS). A pool of 47 candidate items for this measure had been previously developed through qualitative research. In this study, youth with chronic pain associated with juvenile fibromyalgia (JFM), juvenile idiopathic arthritis (JIA), or sickle cell disease (SCD) (ages 8 to 18 years) from three pediatric centers completed all 47 candidate items for development of the pain behavior item bank along with established measures of pain interference, depressive symptoms, fatigue, average pain intensity, and pain catastrophizing...
April 5, 2017: Pain
https://www.readbyqxmd.com/read/28394218/poor-sleep-in-adults-with-pediatric-onset-spinal-cord-injury-associations-with-pain-health-and-activity
#13
Alicia M January, Kathy Zebracki, Kathleen M Chlan, Lawrence C Vogel
OBJECTIVE: To investigate medical complications that increase risk for poor sleep in adults with pediatric-onset spinal cord injury (SCI) and explore the relation of poor sleep to psychosocial outcomes. METHOD: This was a cross-sectional study of individuals with pediatric-onset SCI interviewed between 2011-2015. Participants were recruited from a pediatric specialty hospital and answered questions about demographics, injury characteristics, pain, and medical complications and completed standardized outcome measures, including: Pittsburgh Sleep Quality Index, SF12v2 Health Survey, Craig Handicap Assessment and Recording Technique (CHART), and Subjective Happiness Scale...
April 10, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28393667/disability-quality-of-life-and-pain-coping-in-pediatric-migraine-an-observational-study
#14
Serena L Orr, Suzanne N Christie, Salwa Akiki, Hugh J McMillan
OBJECTIVES: The objective was to examine the relationship between disability, health-related quality of life (HrQoL), and pain coping in pediatric migraineurs. METHOD: Eighty-five patients with migraine were recruited from Pediatric Neurology clinics. Participants completed the Pediatric Migraine Disability Assessment Scale, the Pediatric Quality of Life Inventory, the Pain Coping Questionnaire, and the Pain Catastrophizing Scale. Means were compared to published norms using t-tests...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28378183/-therapy-outcome-one-year-after-pediatric-outpatient-chronic-pain-evaluation-chronic-pain-grading-cpg-for-adolescent-pain-patients
#15
L Stahlschmidt, F Barth, B Zernikow, J Wager
BACKGROUND: Interdisciplinary pain treatment has been shown to be effective for children and adolescents with chronic pain, both in an outpatient and inpatient setting. Until now, the effectiveness has been analyzed with various outcome measures. Although it has only rarely been used for adolescents so far, Chronic Pain Grading (CPG) developed by Von Korff could be an appropriate general outcome measure. OBJECTIVE: The study aims at prospectively investigating and comparing the therapy outcome one year after initial presentation for both outpatients and inpatients using the CPG...
April 4, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28378107/temporal-daily-associations-among-sleep-and-pain-in-treatment-seeking-youth-with-acute-musculoskeletal-pain
#16
Amy Lewandowski Holley, Jennifer Rabbitts, Chuan Zhou, Lindsay Durkin, Tonya M Palermo
Sleep is an important health risk factor. In the context of pediatric chronic pain, sleep is often impaired and temporal daily associations link sleep deficiency to subsequent increased pain. It is unknown whether similar temporal relationships exist for youth with acute pain. Thus, we characterized sleep in youth with acute musculoskeletal (MSK) pain to examine daily sleep-pain associations. Participants were 67 youth (10-17 years) with acute MSK pain (<1 month duration). Youth underwent eight nights of actigraphic sleep monitoring and completed twice daily pain diaries...
April 4, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28353009/acute-kidney-injury-in-children-with-sickle-cell-disease-compounding-a-chronic-problem
#17
EDITORIAL
Cherry Mammen, Mei Lin Bissonnette, Douglas G Matsell
In an article recently published in Pediatric Nephrology, Baddam and colleagues discuss the relatively underreported clinical problem of repeated episodes of acute kidney injury (AKI) in children with sickle cell disease (SCD). Their report is a cautionary note about the importance of repeated kidney injury on the background of underlying chronic kidney injury and its potential implications on long-term kidney outcome. In children and adults with SCD, this includes the effects of repeated vaso-occlusive crises and the management of these painful episodes with non-steroidal anti-inflammatory drugs...
March 28, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28348582/genetic-background-and-clinical-characters-of-pediatric-chronic-pancreatitis-data-and-implications-from-the-east
#18
Muyun Liu, Tian Xia, Di Zhang, Lianghao Hu, Zhuan Liao, Chang Sun, Zhaoshen Li
Background. The clinical pattern and genetic background of juvenile idiopathic chronic pancreatitis (ICP) are yet unclear. Methods. A retrospective study of 73 Chinese juvenile ICP patients was performed, and genetic tests were carried out to detect relevant mutations using direct sequencing technique and high-resolution melting technique. Subjects without pancreatitis served as controls. Results. The SPINK1 c.194+2T>C variant was present in 56.16% and 42.00% of juvenile and adult ICP patients, respectively (p = 0...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28339998/executive-functioning-in-pediatric-chronic-pain-do-deficits-exist
#19
Karen E Weiss, Cynthia Harbeck-Weber, Michael J Zaccariello, Jacqueline N Kimondo, Tracy E Harrison, Barbara K Bruce
Objective. : Despite ample research documenting deficits in executive functioning for adults with chronic pain, the literature on pediatric patients with chronic pain is limited and provides mixed results. The current study sought to further investigate the nature of executive dysfunction in this population and also examine the relationships between pain intensity, duration, and catastrophizing with sustained attention, working memory, and self- and parent-report of executive functioning...
March 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28339428/does-conservative-treatment-change-the-brain-in-patients-with-chronic-musculoskeletal-pain-a-systematic-review
#20
Jeroen Kregel, Iris Coppieters, Robby DePauw, Anneleen Malfliet, Lieven Danneels, Jo Nijs, Barbara Cagnie, Mira Meeus
BACKGROUND: Chronic musculoskeletal pain is characterized by maladaptive central neuroplastic changes. Many observational studies have demonstrated that chronic pain states are associated with brain alterations regarding structure and/or function. Rehabilitation of patients with chronic musculoskeletal pain may include cognitive, exercise, or multimodal therapies. OBJECTIVE: The current review aims to provide a constructive overview of the existing literature reporting neural correlates, based on brain magnetic resonance imaging (MRI) techniques, following conservative treatment in chronic musculoskeletal pain patients...
March 2017: Pain Physician
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