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Pediatric anxiety

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https://www.readbyqxmd.com/read/29044497/pediatric-headache-and-sleep-disturbance-a-comparison-of-diagnostic-groups
#1
Jonathan Rabner, Karen J Kaczynski, Laura E Simons, Alyssa LeBel
OBJECTIVE: To examine whether sleep disturbance differs by headache diagnosis in a pediatric sample, and whether this effect remains when other factors affecting sleep are included. BACKGROUND: Primary headache disorders can be severe and disabling, impacting a child's functioning and quality of life. Many children and adolescents with chronic headaches also experience sleep difficulties, and there is likely a bidirectional relationship between headaches and sleep difficulties...
October 17, 2017: Headache
https://www.readbyqxmd.com/read/29037795/the-burden-of-hospital-readmissions-among-pediatric-patients-with-inflammatory-bowel-disease
#2
Edward L Barnes, Bharati Kochar, Millie D Long, Christopher F Martin, Seth D Crockett, Joshua R Korzenik, Michael D Kappelman
OBJECTIVE: To evaluate the burden and predictors of hospital readmissions among pediatric patients with inflammatory bowel disease using the Nationwide Readmissions Database. STUDY DESIGN: We performed a retrospective cohort study using 2013 Nationwide Readmissions Database. International Classification of Diseases, Ninth Revision, Clinical Modification codes were used to identify patients <18 years with diagnoses of ulcerative colitis (UC) or Crohn's disease (CD)...
October 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29035574/a-6-month-open-label-extension-study-of-vortioxetine-in-pediatric-patients-with-depressive-or-anxiety-disorders
#3
Robert L Findling, Adelaide S Robb, Melissa P DelBello, Michael Huss, Nora K McNamara, Elias H Sarkis, Russell E Scheffer, Lis H Poulsen, Grace Chen, Ole M Lemming, Philippe Auby
OBJECTIVES: In this 6-month open-label extension (OLE) of NCT01491035 (a 14-day, open-label, pharmacokinetic/safety lead-in study), the long-term safety and tolerability of vortioxetine (5-20 mg/day) were investigated in children and adolescents with a DSM-IV-TR™ diagnosis of depressive or anxiety disorder in the United States or Germany. The study also was designed to provide data to inform dose selection and titration in future pediatric studies with vortioxetine. METHODS: Safety evaluations included spontaneously reported adverse events (AEs), the Columbia Suicide Severity Rating Scale (C-SSRS), and the Pediatric Adverse Events Rating Scale (PAERS; clinician administered)...
October 16, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29031217/quality-of-life-and-burden-in-caregivers-of-youth-with-obsessive-compulsive-disorder-presenting-for-intensive-treatment
#4
Monica S Wu, Rebecca Hamblin, Joshua Nadeau, Jessica Simmons, Ashley Smith, Meredith Wilson, Stephanie Eken, Brent Small, Vicky Phares, Eric A Storch
BACKGROUND: Pediatric obsessive-compulsive disorder (OCD) is associated with deleterious familial effects; caregivers are often enmeshed in the disorder and can experience considerable burden and decreased quality of life (QoL). Consequently, this study examined burden and QoL in caregivers of youth with OCD enrolled in an intensive outpatient or partial hospitalization program. METHOD: The relationships between caregiver QoL and burden and the following variables were investigated: OCD symptom severity, functioning (youth functional impairment, general family functioning), family (family accommodation, parental relationship satisfaction, positive aspects of caregiving), and comorbid psychopathology (caregiver anxiety and depressive symptoms, youth internalizing and externalizing behaviors)...
August 30, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29030938/opioid-use-disorder-and-misuse-a-review-of-the-epidemiology-and-medical-implications-for-pediatric-anesthesiologists
#5
REVIEW
Emily Knipper, Caleb J Banta-Green, Nathalia Jimenez
This educational review presents an overview of opioid use disorder, misuse and overdose among adolescents, and the clinical implications for anesthesiologists. It provides definitions, discusses the epidemiology worldwide, (focusing on North America), and emphasizes the clinical implications of patients with chronic opioid exposure, including perioperative pain management, as well as opioid overdose and prolonged use of opioids after acute exposure. In the USA, opioid use disorder and negative outcomes related to opioids rose dramatically from 1999-2010; concomitantly heroin use and fatal overdoses have increased as heroin use is associated with the disordered use of licit opioids...
November 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29026329/pharmacogenomic-testing-aiding-in-the-management-of-psychotropic-therapy-for-adolescents-with-autism-spectrum-disorders
#6
Seuli Bose-Brill, Jinming Xing, Debra J Barnette, Christopher Hanks
Adolescents with autism have higher rates of anxiety than the general adolescent population. They often struggle to express psychological symptoms verbally where their symptoms may manifest as withdrawal and agitation. Adolescent patients with autism have higher rates of polypharmacy and high-risk psychiatric medication use (eg, atypical antipsychotics) than other patients with psychiatric illness. Primary care pediatricians are at the front lines of psychiatric management for patients with autism. Yet, they have inadequate access to pediatric psychiatry for complex medication management...
2017: Pharmacogenomics and Personalized Medicine
https://www.readbyqxmd.com/read/29019627/dry-drowning-myths-and-misconceptions
#7
M Denise Dowd
Drowning is a leading cause of death in children and is highly preventable. More than 10 people die of drowning in the United States each day, most of them adults. Rates of drowning are highest in children given their developmental vulnerabilities. Drowning incidents that result in cardiopulmonary arrest have a straightforward emergency clinical response, but the management approaches to the more common scenario of brief, nonfatal submersion is less clear. Clinicians must make clinical-care decisions based on evidence to provide safe and effective care in a timely manner and to help families avoid unnecessary anxiety...
October 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/29019042/long-term-outcomes-of-adult-medulloblastoma-patients-treated-with-radiotherapy
#8
Brian De, Kathryn Beal, Kevin C De Braganca, Mark M Souweidane, Ira J Dunkel, Yasmin Khakoo, Stephen W Gilheeney, Lisa M DeAngelis, Paul Menzel, Suchit H Patel, Suzanne L Wolden
Medulloblastoma (MB) is rare in adults and treatment guidelines are consequently not well-established. Few modern series have reported long-term follow-up and treatment sequelae. We examined long-term outcomes of adult MB patients at one institution. Records of 29 consecutive patients (18 male, 11 female) aged ≥ 18 years who received radiotherapy (RT) for primary MB from 1990 to 2016 were reviewed. Median age at diagnosis was 28 years (range 18-72 years). Seventeen patients were standard risk and 12 were high risk...
October 10, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28992870/evaluating-clinical-effectiveness-and-pharmacokinetic-profile-of-atomized-intranasal-midazolam-in-children-undergoing-laceration-repair
#9
Sarah A Mellion, David Bourne, Lina Brou, Alison Brent, Kathleen Adelgais, Jeffrey Galinkin, Joseph Wathen
BACKGROUND: Atomized intranasal midazolam is a common adjunct in pediatrics for procedural anxiolysis. There are no previous studies of validated anxiety scores with pharmacokinetic data to support optimal procedure timing. OBJECTIVES: We describe the clinical and pharmacokinetic profile of atomized intranasal midazolam in children presenting for laceration repair. METHODS: Children 11 months to 7 years of age and weighing <26 kg received 0...
September 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28990850/the-relationship-between-toxoplasma-gondii-igg-antibodies-and-generalized-anxiety-disorder-and-obsessive-compulsive-disorder-in-children-and-adolescents-a-new-approach
#10
İsmail Akaltun, Soner Sertan Kara, Tayfun Kara
AIM: Toxoplasma gondii may play a role in the development of psychiatric diseases by affecting the brain. The purpose of this study was to examine the relation between serum toxoplasma IgG positivity and obsessive-compulsive disorder (OCD) and generalized anxiety disorder (GAD) in children and adolescents. METHOD: Sixty patients diagnosed with OCD and 60 patients with GAD presenting to the pediatric psychiatry clinic, together with 60 control group subjects with no psychiatric diagnosis, were included in the study...
October 9, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28985975/mental-health-screening-of-medically-admitted-patients-with-cystic-fibrosis
#11
Georgina Garcia, Carolyn Snell, Gregory Sawicki, Laura E Simons
BACKGROUND: Multi-national studies have identified an increased risk for depression and anxiety among the cystic fibrosis population. People with cystic fibrosis and depression have decreased lung function, adherence, and quality of life, and increased health care utilization. This is a pilot study of mental health screening and referral of patients with cystic fibrosis in a large tertiary medical center. OBJECTIVE: Patients with a diagnosis of cystic fibrosis aged 8 and older, medically admitted to a tertiary hospital, were screened for eligibility and offered mental health screening for depression and anxiety...
August 30, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28980091/biopsychosocial-predictors-of-quality-of-life-outcomes-in-pediatric-congenital-heart-disease
#12
Michelle M Ernst, Bradley S Marino, Amy Cassedy, Carrie Piazza-Waggoner, Rodney C Franklin, Katherine Brown, Jo Wray
The purpose of this prospective multi-center cross-sectional study was to identify key biopsychosocial factors that impact quality of life (QOL) of youth with congenital heart disease (CHD). Patient-parent pairs were recruited at a regular hospital follow-up visit. Patient- and parent-proxy-reported QOL were assessed using the Pediatric Cardiac Quality of Life Inventory (PCQLI). Wallander's and Varni's disability-stress coping model guided factor selection, which included disease factors, educational impairment, psychosocial stress, child psychological and parent/family factors...
October 4, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28970147/fructans-exacerbate-symptoms-in-a-subset-of-children-with-irritable-bowel-syndrome
#13
B P Chumpitazi, A R McMeans, A Vaughan, A Ali, S Orlando, A Elsaadi, R J Shulman
BACKGROUND & AIMS: Dietary fructans exacerbate symptoms in some, but not all, adults with irritable bowel syndrome (IBS). We sought to determine whether fructans worsen symptoms in children with IBS and whether clinical and psychosocial factors, and/or gas production, can identify those who are fructan sensitive. METHODS: We performed a double-blind placebo-controlled (maltodextrin) cross-over trial of 23 children with IBS, based on pediatric Rome III criteria, from September 2014 through December 2016...
September 29, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28968342/attention-bias-modification-training-for-adolescents-with-chronic-pain-a-randomized-placebocontrolled-trial
#14
Lauren C Heathcote, Konrad Jacobs, Dimitri M L Van Ryckeghem, Emma Fisher, Christopher Eccleston, Elaine Fox, Jennifer Y F Lau
Attention bias for pain-related information is theorised to maintain chronic pain, indicating that changing this bias could improve pain-related outcomes. Modifying attention biases in adolescents, when chronic pain often first emerges, may be particularly beneficial. We report here a randomized, placebo-controlled, parallel-group trial of Attention Bias Modification (ABM) training in adolescents with chronic non-cancer pain. Adolescent patients (N=66) were randomly assigned to complete multiple sessions of dot-probe ABM training (N=23), placebo training (N=22), or no training (waitlist; N=21) across a period of four weeks...
September 29, 2017: Pain
https://www.readbyqxmd.com/read/28957984/health-related-quality-of-life-in-adolescent-patients-with-hepatitis-c-genotype-1-treated-with-sofosbuvir-and-ledipasvir
#15
Zobair M Younossi, Maria Stepanova, William Balistreri, Kathleen Schwarz, Karen F Murray, Philip Rosenthal, Sanjay Bansal, Sharon Hunt
OBJECTIVE: To assess the impact of treatment with ledipasvir/sofosbuvir (LDV/SOF) on the health-related quality of life (HRQL) of pediatric patients with chronic hepatitis C virus (HCV) infection. METHODS: Adolescents (12-17 years) with HCV were treated with LDV/SOF (90 mg/400 mg daily) for 12 weeks. HRQL was assessed using the PedsQLv4.0-SF15 completed by the children and caregivers before, during, and after treatment. RESULTS: We included 100 adolescents with HCV genotype 1 infection [14...
September 27, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28956620/monotherapy-insufficient-in-severe-anxiety-predictors-and-moderators-in-the-child-adolescent-anxiety-multimodal-study
#16
Jerome H Taylor, Eli R Lebowitz, Ewgeni Jakubovski, Catherine G Coughlin, Wendy K Silverman, Michael H Bloch
This secondary analysis of the Child/Adolescent Anxiety Multimodal Study (CAMS) used baseline patient characteristics to identify prognostic subgroups of children based on likelihood of remission. We also investigated predictors and moderators of outcome. CAMS randomized 488 youths with generalized, social, and separation anxiety disorders to cognitive behavioral therapy (CBT), sertraline, both, or pill placebo. Outcomes were Week 12 child, parent, and independent evaluator (IE) ratings of child anxiety. We used receiver operating characteristics analysis and stepwise regression to identify predictors and moderators of outcome...
September 28, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28953730/age-related-differences-in-psychosocial-function-of-children-with-craniofacial-anomalies
#17
Elizabeth J Volpicelli, Miles J Pfaff, Kevin Hakimi, James P Bradley, R Christian Solem, Justine C Lee
BACKGROUND: Age is a frequent consideration for surgical timing in pediatric craniofacial surgery for optimal psychosocial development. However, systematic evaluations of the effects of age in children under active treatment have not been thoroughly evaluated. METHODS: Ninety-nine patients (age, 8 to 17 years; 46.5 percent male) from the University of California, Los Angeles, Craniofacial Clinic were prospectively evaluated using the Pediatric Patient-Reported Outcomes Measurement Information System to assess anger, anxiety, depression, and quality of peer relationships...
October 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28945206/psychological-distress-and-quality-of-life-in-pediatric-crohn-disease-impact-of-pain-and-disease-state
#18
Robyn Lewis Claar, Miranda A L van Tilburg, Bisher Abdullah, Shelby Langer, Dalia Sherif, William E Whitehead, Douglas A Drossman, Rona L Levy
OBJECTIVES: For patients with Crohn disease (CD), symptom reporting may not coincide with disease state; patients in remission may continue to report symptoms and pain, whereas other patients may be symptom-free despite a flare. This phenomenon has been documented in adults but only recently assessed in pediatric patients. The present study assessed the role of pain reporting and disease state in pediatric patients with CD in understanding psychological distress and quality of life. METHODS: Participants included 116 children and adolescents ages 8 to 18 years with CD who completed self-report questionnaires assessing pain, disease symptoms, depression, anxiety, functional disability, and quality of life...
October 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28940497/scrotal-hair-in-infancy-a-case-series
#19
Zeynep Uzan Tatlı, Ulku Gul, Nihal Hatipoglu, Selim Kurtoglu
Scrotal hair is a clinical condition that occurs rarely in infancy. Its prevalence is not known. We present a retrospective analysis of six patients referred to our pediatric endocrinology clinic. Except for scrotal hair development, all physical examinations were normal. Underlying pathologic hyperandrogenism was excluded in each case. Clinical regression was observed in all four infants with documented follow-up visits. Scrotal hair in infancy is not well known to most pediatricians and dermatologists and can cause parental anxiety...
September 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28939545/protocol-for-co-design-development-and-open-trial-of-a-prototype-game-based-ehealth-intervention-to-treat-anxiety-in-young-people-with-long-term-physical-conditions
#20
Hiran Thabrew, Karolina Stasiak, Sally Merry
BACKGROUND: Approximately 10% to 12% of New Zealand young people (and 21% of Maori young people) have long-term physical conditions and are more likely to develop psychological problems, particularly anxiety and depression. Delayed treatment leads to worse management of physical conditions, school absence, and poorer long-term outcomes. Recently, electronic health (eHealth) interventions have been shown to be as good as face-to-face therapy and biofeedback techniques have been shown to enhance relaxation during the treatment of anxiety...
September 22, 2017: JMIR Research Protocols
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