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https://www.readbyqxmd.com/read/27895682/development-and-clinical-implementation-of-a-new-template-for-mri-based-intracavitary-interstitial-gynecologic-brachytherapy-for-locally-advanced-cervical-cancer-from-ct-based-mupit-to-the-mri-compatible-template-benidorm-ten-years-of-experience
#1
Silvia Rodríguez Villalba, Jose Richart Sancho, Antonio Otal Palacín, Jose Perez-Calatayud, Manuel Santos Ortega
PURPOSE: To study outcome and toxicity in 59 patients with locally advanced cervix carcinoma treated with computed tomography (CT)-based Martinez universal perineal interstitial template (MUPIT) and the new magnetic resonance imaging (MRI)-compatible template Benidorm (TB). MATERIAL AND METHODS: From December 2005 to October 2015, we retrospectively analyzed 34 patients treated with MUPIT and 25 treated with the TB. Six 4 Gy fractions were prescribed to the clinical target volume (CTV) combined with external beam radiotherapy (EBRT)...
October 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27895680/the-role-of-interstitial-brachytherapy-in-the-management-of-primary-radiation-therapy-for-uterine-cervical-cancer
#2
Naoya Murakami, Kazuma Kobayashi, Tomoyasu Kato, Satoshi Nakamura, Akihisa Wakita, Hiroyuki Okamoto, Satoshi Shima, Keisuke Tsuchida, Tairo Kashihara, Ken Harada, Kana Takahashi, Rei Umezawa, Koji Inaba, Yoshinori Ito, Hiroshi Igaki, Jun Itami
PURPOSE: The aim of this study was to report the clinical results of uterine cervical cancer patients treated by primary radiation therapy including brachytherapy, and investigate the role of interstitial brachytherapy (ISBT). MATERIAL AND METHODS: All consecutive uterine cervical cancer patients who were treated by primary radiation therapy were reviewed, and those who were treated by ISBT were further investigated for clinical outcomes and related toxicities. RESULTS: From December 2008 to October 2014, 209 consecutive uterine cervical cancer patients were treated with primary radiation therapy...
October 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27882055/determinants-of-patient-delay-in-seeking-diagnosis-and-treatment-among-moroccan-women-with-cervical-cancer
#3
Fatima Ouasmani, Zaki Hanchi, Bouchra Haddou Rahou, Rachid Bekkali, Samir Ahid, Abdelhalem Mesfioui
Introduction. This study sought to investigate potential determinants of patient delay among Moroccan women with cervical cancer. Methods. A cross-sectional study was conducted from June 2014 to June 2015 at the National Institute of Oncology in Rabat. Data were collected using questionnaire among patients with cervical cancer locally advanced or metastatic (stages IIA-IVB). Medical records were abstracted to complete clinical information. An interval longer than 90 days between discovery of initial symptoms and presentation to a provider was defined as a patient delay...
2016: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/27864938/harms-of-cervical-cancer-screening-in-the-united-states-and-the-netherlands
#4
Dik Habbema, Sheila Weinmann, Marc Arbyn, Aruna Kamineni, Andrew E Williams, Inge McM de Kok, Folkert van Kemenade, Terry S Field, Joost van Rosmalen, Martin Brown
We studied harms related to cervical cancer screening and management of screen-positive women in the United States (US) and the Netherlands. We utilised data from four US integrated health care systems (SEARCH), the US National Health Interview Survey, New Mexico state, the Netherlands national histopathology registry, and included studies on adverse health effects of cervical screening. We compared the number of Papanicolaou (Pap) smear tests, abnormal test results, punch biopsies, treatments, health problems (anxiety, pain, bleeding, and discharge), and preterm births associated with excisional treatments...
November 16, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27836494/associations-between-vaginal-infections-and-potential-high-risk-and-high-risk-human-papillomavirus-genotypes-in-female-sex-workers-in-western-kenya
#5
Sonia Menon, Davy Vanden Broeck, Rodolfo Rossi, Emiliono Ogbe, Stacy Harmon, Hillary Mabeya
PURPOSE: Infection with and persistence of high-risk human papillomavirus (HR HPV) are the strongest risk factors for cervical cancer. Little is known about the prevalence and role of concurrent sexually transmitted infections (STIs) found in HPV-infected female sex workers (FSW) in Africa. This study purports to test our a priori hypotheses that STIs are associated with genotypes pertaining to the α-group species 9. The objectives were to determine the prevalence of bacterial vaginosis (BV), Trichomonas vaginalis, and Candida spp in FSW, the association between these STIs and the prevalence of any potential HR and HR HPV genotypes in FSWs...
November 8, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27736158/long-term-outcomes-of-double-layered-polytetrafluoroethylene-membrane-covered-self-expandable-segmental-metallic-stents-uventa-in-patients-with-chronic-ureteral-obstructions-is-it-really-safe
#6
Myong Kim, Bumsik Hong, Hyung Keun Park
PURPOSE: To evaluate the long-term clinical efficacy and safety of double-layered polytetrafluoroethylene membrane-covered self-expandable segmental metallic stents (Uventa) in patients with chronic ureteral obstruction. MATERIALS AND METHODS: In a retrospective study, a total of 50 ureter units (44 patients) with chronic obstructions were included from July 2010 to May 2015. Indications for Uventa placement were primary stenting for malignant ureteral obstruction, failed conventional polymeric Double-J stent (PS), or percutaneous nephrostomy (PCN) technique, with comorbidities or fears limiting PS/PCN changes, or with irritation or pain due to PS/PCN...
December 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27734113/through-thick-and-thin-a-pictorial-review-of-the-endometrium
#7
Melanie P Caserta, Candice Bolan, M Jennings Clingan
The purpose of this pictorial review is to describe the normal appearance of the endometrium and to provide radiologists with an overview of endometrial pathology utilizing case examples. The normal appearance of the endometrium varies by age, menstrual phase, and hormonal status with differing degrees of acceptable endometrial thickness. Endometrial pathology most often manifests as either focal or diffuse endometrial thickening, and patients frequently present with abnormal vaginal bleeding. Endovaginal ultrasound (US) is the first-line modality for imaging the endometrium...
October 12, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27668208/primary-malignant-melanoma-of-cervix-and-vagina
#8
Jae Hoon Lee, Jisun Yun, Jung-Won Seo, Go-Eun Bae, Jeong-Won Lee, Sang Wun Kim
Primary malignant melanoma (MM) accounts for 1% of all cancers, and only 3% to 7% of these tumors occur in the female genital tract. Data are limited with respect to the basis for treatment recommendations because of the rarity of MM. The overall prognosis of melanomas of the female genital tract is very poor. Two cases of MM of the female genital tract are presented. The first case is of a 70-year-old female patient who complained of left thigh pain and underwent magnetic resonance imaging that showed cervical cancer with involvement of the vagina, bladder, and parametrium, in addition to multiple bony metastases of the proximal femur, acetabulum, and both iliac bones...
September 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27642626/fertility-sparing-surgery-for-the-management-of-young-women-with-embryonal-rhabdomyosarcoma-of-the-cervix-a-case-series
#9
Geneviève Bouchard-Fortier, Raymond H Kim, Lisa Allen, Abha Gupta, Taymaa May
OBJECTIVE: To report three cases of embryonal rhabdomyosarcoma (ERMS) of the cervix in young women successfully treated with fertility-sparing surgery and chemotherapy. METHODS: Between January 2014 and December 2015, three cases of ERMS of the cervix were confirmed in young women at a single tertiary cancer center. All cases were managed by a pediatric oncologist and a gynecologic oncologist with a combination of surgery and chemotherapy. Fertility-sparing surgeries (cervical conization or robotic-assisted radical trachelectomy) were offered to patients depending on the tumor size...
November 2016: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/27636902/the-prevalence-of-hpv-types-in-women-with-cin-2-3-or-cervical-cancer-in-haifa-district-israel
#10
Efraim Siegler, Karin Sharir, Ofer Lavie, Pninit Saked-Misan, Lena Machulki, Ron Auslender, Yakir Segev
BACKGROUND: Human Papilloma Virus (HPV) is classified as biologic carcinogen causing cervical cancer. Our aim was to identify all the HPV types responsible for cervical cancer and pre-cervical cancer in Israel. METHODS: This study included 226 women, diagnosed with CIN 2-3 and 115 women diagnosed with cervical cancer, and tested for all HPV typing during the period of January 2006 to May 2013. RESULTS: HPV was detected in 92.9% of women with CIN 2-3 and HPV-HR was detected in 85...
September 16, 2016: Minerva Ginecologica
https://www.readbyqxmd.com/read/27618814/epidemiology-and-outcome-of-cervical-cancer-in-national-institute-of-morocco
#11
Sanaa Elmajjaoui, Nabil Ismaili, Hanane El Kacemi, Tayeb Kebdani, Hassan Sifat, Noureddine Benjaafar
BACKGROUND: On behalf of the medical staff of the National Institute of Oncology of Rabat, we conducted a retrospective study to report epidemiology and 5-year outcomes of cervical carcinoma in Moroccan women. METHODS: We reviewed all women diagnosed with invasive cervical carcinoma in our institute between January 2006 and December 2006. Outcomes and prognoses are analyzed in patients who received at least one treatment. RESULTS: The analysis included 646 women...
2016: BMC Women's Health
https://www.readbyqxmd.com/read/27590393/salvage-therapy-in-acute-life-threatening-vaginal-bleeding-of-cervical-cancer-hypogastric-artery-embolization
#12
Sema Süzen Çaypınar, Hakan Güraslan, Baki Şentürk, Hüseyin Cengiz, Levent Yaşar
No abstract text is available yet for this article.
August 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27547046/femilis-%C3%A2-60-levonorgestrel-releasing-intrauterine-system-a-review-of-10-years-of-clinical-experience
#13
REVIEW
Dirk Wildemeersch, Amaury Andrade, Norman Goldstuck
OBJECTIVE: The aim of this study was to update the clinical experience with the Femilis® 60 levonorgestrel-releasing intrauterine system (LNG-IUS), now up to 10 years in parous and nulliparous women, particularly with regard to ease and safety of insertion, contraceptive performance, retention, acceptability, continuation of use, impact on menstrual blood loss (MBL), and duration of action. STUDY DESIGN: Using the Femilis® 60 LNG-IUS releasing 20 µg of levonorgestrel/day, the following studies were conducted: an open, prospective noncomparative contraceptive study, an MBL study, a perimenopausal study, a study for the treatment of endometrial hyperplasia, and early cancer of the uterus, a residue study...
2016: Clinical Medicine Insights. Reproductive Health
https://www.readbyqxmd.com/read/27476847/thirty-day-readmission-and-reoperation-after-surgery-for-spinal-tumors-a-national-surgical-quality-improvement-program-analysis
#14
Aditya V Karhade, Viren S Vasudeva, Hormuzdiyar H Dasenbrock, Yi Lu, William B Gormley, Michael W Groff, John H Chi, Timothy R Smith
OBJECTIVE The goal of this study was to use a large national registry to evaluate the 30-day cumulative incidence and predictors of adverse events, readmissions, and reoperations after surgery for primary and secondary spinal tumors. METHODS Data from adult patients who underwent surgery for spinal tumors (2011-2014) were extracted from the prospective National Surgical Quality Improvement Program (NSQIP) registry. Multivariable logistic regression was used to evaluate predictors of reoperation, readmission, and major complications (death, neurological, cardiopulmonary, venous thromboembolism [VTE], surgical site infection [SSI], and sepsis)...
August 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27409093/-actinic-enteritis-as-a-cause-of-digestive-bleeding-of-obscure-origin
#15
Luis Vásquez, Julissa Guevara, Victor Aguilar, Monica Menéndez, Eduar Bravo, Patricia Guzman Rojas, Catherina Pichilingue, Arturo Zegarra, Jorge Huerta-Mercado, José Pinto, Ricardo Prochazka, Vanessa Valenzuela, Alejandro Bussalleu
Chronic actinic enteritis is a malfunction of the small bowel, occurring in the 6 months post-radiotherapy, and it can be manifestated as malabsortion, stenosis, fistula formation, local abscesses, perforation and bleeding, We report a case of an elderly patient who presents an episode of obscure gastrointestinal bleeding (OGIB) secondary to actinic enteritis. She is a 64-year- old female patient with the past medical history of cervical cancer who received radiotherapy and brachytherapy. One year after the treatment, the patient presents a chronic episode of melena and symptomatic anemia and 1 week before the admission she had hematochezia...
April 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/27396811/dose-volume-effect-relationships-for-late-rectal-morbidity-in-patients-treated-with-chemoradiation-and-mri-guided-adaptive-brachytherapy-for-locally-advanced-cervical-cancer-results-from-the-prospective-multicenter-embrace-study
#16
Renaud Mazeron, Lars U Fokdal, Kathrin Kirchheiner, Petra Georg, Noha Jastaniyah, Barbara Šegedin, Umesh Mahantshetty, Peter Hoskin, Ina Jürgenliemk-Schulz, Christian Kirisists, Jacob C Lindegaard, Wolfgang Dörr, Christine Haie-Meder, Kari Tanderup, Richard Pötter
PURPOSE: To establish dose volume-effect relationships predicting late rectal morbidity in cervix cancer patients treated with concomitant chemoradiation and MRI-guided adaptive brachytherapy (IBABT) within the prospective EMBRACE study. MATERIAL AND METHOD: All patients were treated with curative intent according to institutional protocols with chemoradiation and IGABT. Reporting followed the GEC-ESTRO recommendations ( [Formula: see text] , [Formula: see text] ), applying bioeffect modeling (linear quadratic model) with equieffective doses (EQD23)...
July 7, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27354119/synchronous-endometrioid-adenocarcinomas-in-the-uterine-cervix-and-corpus
#17
Takeshi Obata, Mitsuhiro Nakamura, Yasunari Mizumoto, Takeo Matsumoto, Masahiro Takakura, Hiroshi Fujiwara
It is frequently difficult to distinguish multiple primary carcinomas from single primary carcinoma with metastasis. Here, we report a case of synchronous endometrioid adenocarcinomas that independently occurred in the uterine cervix and corpus. A 47-year-old woman complaining of genital bleeding was preoperatively diagnosed with cervical adenocarcinoma with an endometrial lesion. On surgical treatment, two separate malignant lesions bearing endometrioid adenocarcinoma were identified in the uterine cervix and cavity...
June 29, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27347355/chemotherapy-induced-endometrial-pathology-mimicry-of-malignancy-and-viral-endometritis
#18
Eun Kyung Kim, Gun Yoon, Hyun-Soo Kim
Chemotherapy is a common type of preoperative neoadjuvant treatment and postoperative adjuvant or palliative therapy for many different types of malignancies. Certain chemotherapeutic agents can induce bizarre epithelial atypia that mimics malignancy. Unfamiliarity with these changes could potentially cause confusion with a neoplastic or infectious process. The endometrium is one of the few sites where chemotherapy-induced epithelial atypia has not been appreciated. We identified four patients with marked cytologic atypia of the endometrial glandular epithelium from the surgical pathology files of Severance Hospital...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27336876/clinical-outcomes-in-cervical-cancer-patients-treated-by-fdg-pet-ct-based-3-dimensional-planning-for-the-first-brachytherapy-session
#19
Dongryul Oh, Seung Jae Huh, Won Park, Sang Gyu Ju, Heerim Nam, Jeong Eun Lee
The aim of the study was to evaluate the treatment outcomes in cervical cancer patients treated with 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT)-guided 3-dimensional brachytherapy (3D-BT) planning for the first brachytherapy session.We retrospectively analyzed 87 patients with cervical cancer who received definitive radiotherapy (RT). Primary tumor size was ≤4 cm in 22 patients (25.3%), >4 cm and ≤6 cm in 45 patients (51.7%), and >6 cm in 20 patients (23...
June 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27320647/-initial-experience-in-the-laparoscopic-treatment-of-benign-and-malignant-gynaecological-diseases-in-the-hospital-regional-de-alta-especialidad-in-oaxaca
#20
Sergio Vásquez-Ciriaco, David Isla-Ortiz, Antonio Palomeque-Lopez, Jaime Aron García-Espinoza, Arturo Jarquín-Arremilla, Néstor Alonso Lechuga-García
BACKGROUND: The history of laparoscopic surgery in gynaecological diseases progressed with the advances of Semm, as well as with the development of tools, equipment, and energy that led to its development in all surgical areas, including oncology. OBJECTIVE: To present the initial experience in the laparoscopic treatment of benign and malignant gynaecological disease in the Hospital Regional de Alta Especialidad in Oaxaca. MATERIAL AND METHODS: An analysis was performed on a total of 44 cases, distributed into: type III radical hysterectomy for invasive cervical cancer, hysterectomy type I cervical cancer in situ, extrafascial hysterectomy for benign disease, routine endometrium, ovary and routine salpingo-oophorectomy...
June 16, 2016: Cirugia y Cirujanos
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