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https://www.readbyqxmd.com/read/29679342/fundoplication-with-180-degree-wrap-during-esophagogastrostomy-after-robotic-proximal-gastrectomy-for-early-gastric-cancer
#1
Toshiyasu Ojima, Mikihito Nakamori, Masaki Nakamura, Keiji Hayata, Shimpei Maruoka, Hiroki Yamaue
BACKGROUND: Compared with total gastrectomy, proximal gastrectomy (PG) has potential advantages from a nutritional perspective, such as anemia and postoperative loss of body weight. However, PG is associated with some postoperative functional disorders, such as reflux esophagus (13-31%) and anastomotic stenosis (3-29%).1 We therefore developed a new procedure for fundoplication during esophago-gastrostomy after robotic PG (RPG). METHODS: We performed RPG for early gastric cancer localized in the upper third of the stomach using the da Vinci Surgical System (Intuitive, Sunnyvale, CA)...
April 20, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29624141/management-simulations-for-lean-healthcare-exploiting-the-potentials-of-role-playing
#2
Federico Barnabè, Maria Cleofe Giorgino, Jacopo Guercini, Caterina Bianciardi, Vincenzo Mezzatesta
Purpose The purpose of this paper is to investigate the potentials of role-playing (RP) both in training healthcare (HC) professionals to implement tools and improvement actions based on Lean principles, and in supporting group discussion and the sharing of different competencies for the development of Lean HC. Design/methodology/approach The paper presents the case study of an RP simulation called LEAN HEALTHCARE LAB, which is used to train HC professionals at Siena University Hospital. The paper reports and discusses the results of a specific two-day simulation session and of a questionnaire that was distributed to gather feedback from the participants...
April 9, 2018: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/29621113/a-repeated-power-training-enhances-fatigue-resistance-while-reducing-intraset-fluctuations
#3
Oliver Gonzalo-Skok, Julio Tous-Fajardo, Gerard Moras, José Luis Arjol-Serrano, Alberto Mendez-Villanueva
Oliver, GS, Julio, TF, Moras, G, José Luis, AS, and Alberto, MV. A repeated power training enhances fatigue resistance while reducing intraset fluctuations. J Strength Cond Res XX(X): 000-000, 2018-The present study analyzed the effects of adding an upper-body repeated power ability (RPA) training to habitual strength training sessions. Twenty young elite male basketball players were randomly allocated into a control group (CON, n = 10) or repeated power group (RPG, n = 10) and evaluated by 1 repetition maximum (1RM), incremental load, and RPA tests in the bench press exercise before and after a 7-week period and a 4-week cessation period...
April 4, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29587782/knowledge-based-imrt-planning-for-individual-liver-cancer-patients-using-a-novel-specific-model
#4
Gang Yu, Yang Li, Ziwei Feng, Cheng Tao, Zuyi Yu, Baosheng Li, Dengwang Li
BACKGROUND: The purpose of this work is to benchmark RapidPlan against clinical plans for liver Intensity-modulated radiotherapy (IMRT) treatment of patients with special anatomical characteristics, and to investigate the prediction capability of the general model (Model-G) versus our specific model (Model-S). METHODS: A library consisting of 60 liver cancer patients with IMRT planning was used to set up two models (Model-S, Model-G), using the RapidPlan knowledge-based planning system...
March 27, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29565992/clinical-characteristics-and-complications-of-rotavirus-gastroenteritis-in-children-in-east-london-a-retrospective-case-control-study
#5
Konstantinos Karampatsas, Leanne Osborne, May-Li Seah, Cheuk Y W Tong, Andrew J Prendergast
BACKGROUND: Rotavirus is the leading cause of acute gastroenteritis in children and is associated with neurological complications such as seizures and encephalopathy. The aim of this study was to investigate the presentation and complications of rotavirus compared to non-rotavirus gastroenteritis in UK children. METHODS: This was a retrospective, case-control, hospital-based study conducted at three sites in east London, UK. Cases were children aged 1 month to 16 years diagnosed with acute gastroenteritis between 1 June 2011 and 31 December 2013, in whom stool virology investigations confirmed presence of rotavirus by PCR...
2018: PloS One
https://www.readbyqxmd.com/read/29542863/results-from-a-pilot-study-of-a-computer-based-role-playing-game-for-young-people-with-psychosis
#6
Jeffrey Olivet, Morgan Haselden, Sarah Piscitelli, Rachael Kenney, Alexander Shulman, Deborah Medoff, Lisa Dixon
AIM: Recent research on first episode psychosis (FEP) has demonstrated the effectiveness of coordinated specialty care (CSC) models to support young adults and their families, yet few tools exist to promote engagement in care. This study aimed to develop a prototype computer-based role-playing game (RPG) designed for young people who have experienced FEP, and conduct a pilot study to determine feasibility and test whether the game improves consumers' attitudes toward treatment and recovery...
March 15, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29535936/waist-thigh-ratio-a-surrogate-marker-for-type-2-diabetes-mellitus-in-asian-north-indian-patients
#7
Shivanjali Kumar, Kamal Kumar, Sarita Bajaj, Ranjana Kumar, Atul Gogia, Atul Kakar, Shrishti Paul Byotra
Introduction: Diabetes is a major world-wide healthcare problem. Cost effective markers for screening and diagnosis of T2DM are the need of the day especially in developing and under-developed countries. Simple anthropometric measurements may help us in identifying individuals likely to have diabetes. Material and Methods: Data from 1055 North-Indian subjects was analysed. Results: Out of several anthropometric measurements studied, Waist-Thigh ratio (WTR) correlated significantly and positively with all three measures of diabetes i...
January 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29515602/development-of-biofortified-maize-hybrids-through-marker-assisted-stacking-of-%C3%AE-carotene-hydroxylase-lycopene-%C3%AE%C2%B5-cyclase-and-opaque2-genes
#8
Rajkumar U Zunjare, Firoz Hossain, Vignesh Muthusamy, Aanchal Baveja, Hema S Chauhan, Jayant S Bhat, Nepolean Thirunavukkarasu, Supradip Saha, Hari S Gupta
Traditional yellow maize though contains high kernel carotenoids, the concentration of provitamin A (proA) is quite low (<2 μg/g), compared to recommended level (15 μg/g). It also possesses poor endosperm protein quality due to low concentration of lysine and tryptophan. Natural variant of crtRB1 (β -carotene hydroxylase ) and lcyE ( lycopene- ε -cyclase ) cause significant enhancement of proA concentration, while recessive allele, opaque2 ( o2 ) enhances the level of these amino acids. Development of biofortified maize enriched in proA, lysine and tryptophan thus holds significance in alleviation of micronutrient malnutrition...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29471686/annals-express-comparison-of-hba1c-and-glycated-albumin-as-a-control-marker-for-newborn-complications-from-diabetic-women-in-a-multicenter-study-in-japan-japan-glycated-albumin-study-group-study2
#9
Ikki Shimizu, Yuji Hiramatsu, Yasue Omori, Masao Nakabayashi
Background:To clarify the relationship between glycated hemoglobin (HbA1c) and glycated albumin (GA) levels during pregnancy with neonatal outcomes, a multicenter study was conducted by the Japanese Society of Diabetes and Pregnancy. Methods:A total of 136 patients (type 1: n = 47, type 2: n = 89) who enrolled in the study were diagnosed based on the Japanese Diabetes Society diagnostic criteria for diabetes mellitus. Thresholds for HbA1c and GA were set at 5.8 % and 15.8 %, respectively, as the upper limits of the normal reference interval in pregnant women...
January 1, 2018: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/29415073/urbanization-may-reduce-the-risk-of-frost-damage-to-spring-flowers-a-case-study-of-two-shrub-species-in-south-korea
#10
Hyeon-Ju Gim, Chang-Hoi Ho, Jinwon Kim, Eun Ju Lee
Regional warming, owing to urbanization, leads to earlier spring phenological events and may expose plants to hard freeze damage. This study examined the influence of urbanization on the risk of frost damage to spring flowers in South Korea from 1973 to 2015. For the analysis period, we categorized 25 cities into two groups: those showing rapid population growth (rPG) ≥ 200,000, including 13 cities, and those showing no or decreased population growth (nPG), including 12 cities. We then investigated the time from the last frost dates (LFDs) in spring to the first flowering dates (FFDs) for each group...
2018: PloS One
https://www.readbyqxmd.com/read/29325745/chitosan-nanoparticles-cellulose-nanocrystals-nanocomposites-as-a-carrier-system-for-the-controlled-release-of-repaglinide
#11
Wafaa S Abo-Elseoud, Mohammad L Hassan, Magdy W Sabaa, Mona Basha, Enas A Hassan, Shaimaa M Fadel
The aim of the present work was to study the use of cellulose nanocrystals (CNC) and chitosan nanoparticles (CHNP) for developing controlled-release drug delivery system of the anti-hyperglycemic drug Repaglinide (RPG). CNC was isolated from palm fruit stalks by sulfuric acid hydrolysis; the dimensions of the isolated nanocrystals were 86-237 nm in length and 5-7 nm in width. Simple and economic method was used for the fabrication of controlled release drug delivery system from CNC and CHNP loaded with RPG drug via ionic gelation of chitosan in the presence of CNC and RPG...
May 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29227735/effect-of-8-weeks-of-concurrent-plyometric-and-running-training-on-spatiotemporal-and-physiological-variables-of-novice-runners
#12
Josué Gómez-Molina, Ana Ogueta-Alday, Jesus Camara, Christopher Stickley, Juan García-López
Concurrent plyometric and running training has the potential to improve running economy (RE) and performance through increasing muscle strength and power, but the possible effect on spatiotemporal parameters of running has not been studied yet. The aim of this study was to compare the effect of 8 weeks of concurrent plyometric and running training on spatiotemporal parameters and physiological variables of novice runners. Twenty-five male participants were randomly assigned into two training groups; running group (RG) (n = 11) and running + plyometric group (RPG) (n = 14)...
March 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/28993187/inpatient-glucose-values-determining-the-nondiabetic-range-and-use-in-identifying-patients-at-high-risk-for-diabetes
#13
Mary K Rhee, Sandra E Safo, Sandra L Jackson, Wenqiong Xue, Darin E Olson, Qi Long, Diana Barb, J Sonya Haw, Anne M Tomolo, Lawrence S Phillips
BACKGROUND: Many individuals with diabetes remain undiagnosed, leading to delays in treatment and higher risk for subsequent diabetes complications. Despite recommendations for diabetes screening in high-risk groups, the optimal approach is not known. We evaluated the utility of inpatient glucose levels as an opportunistic screening tool for identifying patients at high risk for diabetes. METHODS: We retrospectively examined 462,421 patients in the US Department of Veterans Affairs healthcare system, hospitalized on medical/surgical services in 2000-2010, for ≥3 days, with ≥2 inpatient random plasma glucose (RPG) measurements...
October 6, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28985413/the-challenges-in-the-estimation-of-the-effective-dose-when-wearing-radioprotective-garments
#14
C Saldarriaga Vargas, L Struelens, F Vanhavere
The performance of a single or double dosimetry (SD or DD) algorithm on estimating effective dose wearing radioprotective garments (ERPG) depends on the specific irradiation conditions. This study investigates the photon energies and angles of incidence for which the estimation of ERPG with the personal dose equivalents measured over and under the RPG (Ho and Hu) becomes more challenging. The energy and angular dependences of ERPG, Ho and Hu were Monte Carlo calculated for photon exposures. The personal dosimeter of SCK · CEN was modeled and used to determine Ho and Hu...
January 1, 2018: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28888458/the-high-content-of-%C3%AE-carotene-present-in-orange-pulp-fruits-of-carica-papaya-l-is-not-correlated-with-a-high-expression-of-the-cplcy-%C3%AE-2-gene
#15
Arianna C Chan-León, Humberto Estrella-Maldonado, Pascal Dubé, Gabriela Fuentes Ortiz, Francisco Espadas-Gil, Carlos Talavera May, Jorge Ramírez Prado, Yves Desjardins, Jorge M Santamaría
We investigated the transcriptional regulation of six genes involved in carotenoid biosynthesis, together with the carotenoid accumulation during postharvest ripening of three different papaya genotypes of contrasting pulp color. Red-pulp genotype (RPG) showed the lowest content of yellow pigments (YP), such as β-cryptoxanthin, zeaxanthin, and violaxanthin, together with the lowest relative expression levels (REL) of CpLCY-β2 and CpCHX-β genes. On the contrary, the yellow-pulp genotype (YPG) showed the highest content of YP and the highest REL of CpLCY-β2 and CpCHX-β genes...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28813631/rapid-and-targeted-introgression-of-fgr-gene-through-marker-assisted-backcrossing-in-rice-oryza-sativa-l
#16
Acga Cheng, Ismanizan Ismail, Mohamad Osman, Habibuddin Hashim, Nur Samahah Mohd Zainual
While it is crucial for developing countries like Malaysia to achieve self-sufficiency in rice (Oryza sativa L.), it is equally critical to be able to produce high-quality rice, specifically fragrant rice, which demands are often met through importation. The present study was aimed at developing high-yielding fragrant rice, in a timely and cost-effective manner. A marker-assisted backcross (MABC) approach was optimised to introgress the fragrance gene (fgr) into two high-yielding Malaysian varieties, MR84 and MR219, within two years utilising less than 50 molecular markers...
December 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28797628/refuse-derived-fuel-rdf-production-and-gasification-in-a-pilot-plant-integrated-with-an-otto-cycle-ice-through-aspen-plus%C3%A2-modelling-thermodynamic-and-economic-viability
#17
Albany Milena Lozano Násner, Electo Eduardo Silva Lora, José Carlos Escobar Palacio, Mateus Henrique Rocha, Julian Camilo Restrepo, Osvaldo José Venturini, Albert Ratner
This work deals with the development of a Refuse Derived Fuel (RDF) gasification pilot plant using air as a gasification agent. A downdraft fixed bed reactor is integrated with an Otto cycle Internal Combustion Engine (ICE). Modelling was carried out using the Aspen Plus™ software to predict the ideal operational conditions for maximum efficiency. Thermodynamics package used in the simulation comprised the Non-Random Two-Liquid (NRTL) model and the Hayden-O'Connell (HOC) equation of state. As expected, the results indicated that the Equivalence Ratio (ER) has a direct influence over the gasification temperature and the composition of the Raw Produced Gas (RPG), and effects of ER over the Lower Heating Value (LHV) and Cold Gasification Efficiency (CGE) of the RPG are also discussed...
November 2017: Waste Management
https://www.readbyqxmd.com/read/28739803/chromatin-remodeling-swi-snf-complex-regulates-coenzyme-q-6-synthesis-and-a-metabolic-shift-to-respiration-in-yeast
#18
Agape M Awad, Srivats Venkataramanan, Anish Nag, Anoop Raj Galivanche, Michelle C Bradley, Lauren T Neves, Stephen Douglass, Catherine F Clarke, Tracy L Johnson
Despite its relatively streamlined genome, there are many important examples of regulated RNA splicing in Saccharomyces cerevisiae Here, we report a role for the chromatin remodeler SWI/SNF in respiration, partially via the regulation of splicing. We find that a nutrient-dependent decrease in Snf2 leads to an increase in splicing of the PTC7 transcript. The spliced PTC7 transcript encodes a mitochondrial phosphatase regulator of biosynthesis of coenzyme Q6 (ubiquinone or CoQ6 ) and a mitochondrial redox-active lipid essential for electron and proton transport in respiration...
September 8, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28717973/design-and-development-of-repaglinide-microemulsion-gel-for-transdermal-delivery
#19
Ujwala A Shinde, Sheela H Modani, Kavita H Singh
Microemulsion formulation of repaglinide, a BCS class II hypoglycemic agent with limited oral bioavailability, was developed considering its solubility in various oils, surfactants, and cosurfactants. The pseudo-ternary phase diagrams for microemulsion regions were constructed by water titration method at Km 1:1 and characterized for optical birefringence, percentage transmittance, pH, refractive index, globule size, zeta potential, viscosity, drug content, and thermodynamic stability. To enhance the drug permeation and residence time, the optimized microemulsions having mean globule size of 36...
January 2018: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28678925/gestational-protein-restriction-increases-cardiac-connexin-43-mrna-levels-in-male-adult-rat-offspring
#20
Kamila Fernanda Rossini, Camila Andrea de Oliveira, Hércules Jonas Rebelato, Marcelo Augusto Marreto Esquisatto, Rosana Catisti
Background: The dietary limitation during pregnancy influences the growth and development of the fetus and offspring and their health into adult life. The mechanisms underlying the adverse effects of gestational protein restriction (GPR) in the development of the offspring hearts are not well understood. Objectives: The aim of this study was to evaluate the effects of GPR on cardiac structure in male rat offspring at day 60 after birth (d60). Methods: Pregnant Wistar rats were fed a normal-protein (NP, 17% casein) or low-protein (LP, 6% casein) diet...
July 2017: Arquivos Brasileiros de Cardiologia
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