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https://www.readbyqxmd.com/read/28211003/an-easy-to-build-low-budget-point-of-care-ultrasound-simulator-from-linux-to-a-web-based-solution
#1
Domagoj Damjanovic, Ulrich Goebel, Benedikt Fischer, Martin Huth, Hartmut Breger, Hartmut Buerkle, Axel Schmutz
BACKGROUND: Hands-on training in point-of-care ultrasound (POC-US) should ideally comprise bedside teaching, as well as simulated clinical scenarios. High-fidelity phantoms and portable ultrasound simulation systems are commercially available, however, at considerable costs. This limits their suitability for medical schools. A Linux-based software for Emergency Department Ultrasound Simulation (edus2TM) was developed by Kulyk and Olszynski in 2011. Its feasibility for POC-US education has been well-documented, and shows good acceptance...
December 2017: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/28190709/training-in-minimally-invasive-pancreatic-resections-a-paradigm-shift-away-from-see-one-do-one-teach-one
#2
Melissa E Hogg, Marc G Besselink, Pierre-Alain Clavien, Abe Fingerhut, D Rohan Jeyarajah, David A Kooby, A James Moser, Henry A Pitt, Oliver A Varban, Charles M Vollmer, Herbert J Zeh, Paul Hansen
BACKGROUND: Increased incorporation of minimally invasive pancreatic resections (MIPR) has emerged into hepato-pancreato-biliary practice, however, no standardization exists for its safe adoption. Novel strategies are presented for dissemination of safe MIPR. METHODS: An international State-of-the-Art conference evaluating multiple aspects of MIPR was conducted by a panel of pancreas experts in Sao Paulo, Brazil on April 20, 2016. Training and education issues were discussed regarding the introduction of novel strategies for safe dissemination of MIPR...
February 9, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28183836/low-dose-ct-for-craniosynostosis-preserving-diagnostic-benefit-with-substantial-radiation-dose-reduction
#3
J C Montoya, L J Eckel, D R DeLone, A L Kotsenas, F E Diehn, L Yu, A C Bartley, R E Carter, C H McCollough, J G Fletcher
BACKGROUND AND PURPOSE: Given the positive impact of early intervention for craniosynostosis, CT is often performed for evaluation but radiation dosage remains a concern. We evaluated the potential for substantial radiation dose reduction in pediatric patients with suspected craniosynostosis. MATERIALS AND METHODS: CT projection data from pediatric patients undergoing head CT for suspected craniosynostosis were archived. Simulated lower-dose CT images corresponding to 25%, 10%, and 2% of the applied dose were created using a validated method...
February 9, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28176890/contextualizing-the-relevance-of-basic-sciences-small-group-simulation-with-debrief-for-first-and-second-year-medical-students-in-an-integrated-curriculum
#4
Samara B Ginzburg, Judith Brenner, Michael Cassara, Thomas Kwiatkowski, Joanne M Willey
AIM: There has been a call for increased integration of basic and clinical sciences during preclinical years of undergraduate medical education. Despite the recognition that clinical simulation is an effective pedagogical tool, little has been reported on its use to demonstrate the relevance of basic science principles to the practice of clinical medicine. We hypothesized that simulation with an integrated science and clinical debrief used with early learners would illustrate the importance of basic science principles in clinical diagnosis and management of patients...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28174092/pancreatic-cancer-models-for-translational-research
#5
REVIEW
Diana Behrens, Wolfgang Walther, Iduna Fichtner
Pancreatic cancer is a cruel, progressive disease that is highly metastatic and barely treatable, a situation that is devastating for patients, family members, oncologists, clinicians and scientists. Open questions that need to be resolved by research into pancreatic cancer relate to its aggressiveness, the underlying molecular causes, the factors that promote tumor progression, the ways cancer cells interact with their environments, and whether more effective therapeutic options can be developed. Studies over the last 15 years have provided some partial answers, but in the absence of a real cure the main agenda remains: to identify new therapeutic targets, predictive markers and novel treatment strategies that would help the disease under control...
February 4, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28173759/utilising-identifier-error-variation-in-linkage-of-large-administrative-data-sources
#6
Katie Harron, Gareth Hagger-Johnson, Ruth Gilbert, Harvey Goldstein
BACKGROUND: Linkage of administrative data sources often relies on probabilistic methods using a set of common identifiers (e.g. sex, date of birth, postcode). Variation in data quality on an individual or organisational level (e.g. by hospital) can result in clustering of identifier errors, violating the assumption of independence between identifiers required for traditional probabilistic match weight estimation. This potentially introduces selection bias to the resulting linked dataset...
February 7, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28169943/bedside-glucose-monitoring-is-it-safe-a-new-regulatory-compliant-risk-assessment-evaluation-protocol-in-critically-ill-patient-care-settings
#7
Jeffrey Anton DuBois, Robbert Jan Slingerland, Marion Fokkert, Alain Roman, Nam Khoa Tran, William Clarke, David Alan Sartori, Tina Louise Palmieri, Andrei Malic, Martha Elizabeth Lyon, Andrew William Lyon
OBJECTIVES: New data have emerged from ambulatory and acute care settings about adverse patient events, including death, attributable to erroneous blood glucose meter measurements and leading to questions over their use in critically ill patients. The U.S. Food and Drug Administration published new, more stringent guidelines for glucose meter manufacturers to evaluate the performance of blood glucose meters in critically ill patient settings. The primary objective of this international, multicenter, multidisciplinary clinical study was to develop and apply a rigorous clinical accuracy assessment algorithm, using four distinct statistical tools, to evaluate the clinical accuracy of a blood glucose monitoring system in critically ill patients...
February 6, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28169225/intensity-based-2d-3d-registration-for-lead-localization-in-robot-guided-deep-brain-stimulation
#8
Stefan Hunsche, Dieter Sauner, Faycal El Majdoub, Clemens Neudorfer, Joerg Poggenborg, Axel Gossmann, Mohammad Maarouf
Intraoperative assessment of lead localization has become a standard procedure during deep brain stimulation (DBS) surgery in many centers, allowing immediate verification of targeting accuracy and, if necessary, adjustment of the trajectory. The most suitable imaging modality to determine lead positioning, however, remains controversially discussed. Current approaches entail the implementation of computed tomography and magnetic resonance imaging. In the present study, we adopted the technique of intensity-based 2D 3D registration that is commonly employed in stereotactic radiotherapy and spinal surgery...
February 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28168935/reproducibility-of-a-noninvasive-system-for-eye-positioning-and-monitoring-in-stereotactic-radiotherapy-of-ocular-melanoma
#9
Omar Iskanderani, Dominique Béliveau-Nadeau, Robert Doucet, Geneviève Coulombe, Deborah Pascale, David Roberge
PURPOSE: Our preferred treatment for juxtapapillary choroidal melanoma is stereotactic radiotherapy. We aim to describe our immobilization system and quantify its reproducibility. MATERIALS AND METHODS: Patients were identified in our radiosurgery database. Patients were imaged at computed tomography simulator with an in-house system which allows visual monitoring of the eye as the patient fixates a small target. All patients were reimaged at least once prior to and/or during radiotherapy...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28168706/flow-field-simulations-and-hemolysis-estimates-for-the-food-and-drug-administration-critical-path-initiative-centrifugal-blood-pump
#10
Margaret L Heck, Allen Yen, Trevor A Snyder, Edgar A O'Rear, Dimitrios V Papavassiliou
The design of blood pumps for use in ventricular assist devices, which provide life-saving circulatory support in patients with heart failure, require remarkable precision and attention to detail to replicate the functionality of the native heart. The United States Food and Drug Administration (FDA) initiated a Critical Path Initiative to standardize and facilitate the use of computational fluid dynamics in the study and development of these devices. As a part of the study, a simplified centrifugal blood pump model generated by computer-aided design was released to universities and laboratories nationwide...
February 7, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28168539/assessment-of-residents-readiness-to-perform-lumbar-puncture-a-validation-study
#11
Mikael Johannes Vuokko Henriksen Md, Troels Wienecke Md PhD, Helle Thagesen Md, Rikke Vita Borre Jacobsen Md PhD, Yousif Subhi Md, Charlotte Ringsted Md PhD, Lars Konge Md PhD
BACKGROUND: Lumbar puncture is a common procedure in many specialties. The procedure serves to diagnose life-threatening conditions, often requiring rapid performance. However, junior doctors possess uncertainties regarding performing the procedure and frequently perform below expectations. Hence, proper training and assessment of performance is crucial before entering clinical practice. OBJECTIVE: To develop and collect validity evidence for an assessment tool for lumbar puncture performance, including a standard to determine when trainees are ready for clinical practice...
February 6, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28168128/three-dimensional-printing-of-a-hemorrhagic-cervical-cancer-model-for-postgraduate-gynecological-training
#12
Michael Bartellas, Stephen Ryan, Gregory Doucet, Deanna Murphy, Jacqueline Turner
INTRODUCTION: A realistic hemorrhagic cervical cancer model was three-dimensionally (3D) printed and used in a postgraduate medical simulation training session. MATERIALS AND METHODS: Computer-assisted design (CAD) software was the platform of choice to create and refine the cervical model. Once the prototype was finalized, another software allowed for the addition of a neoplastic mass, which included openings for bleeding from the neoplasm and cervical os. 3D printing was done using two desktop printers and three different materials...
January 1, 2017: Curēus
https://www.readbyqxmd.com/read/28163860/refinement-of-intraocular-pressure-measurements-made-by-ocular-response-analyzer-following-laser-in-situ-keratomileusis-using-m2-90-moria-microkeratome-for-egyptian-myopic-and-astigmatic-patients
#13
Tamer Adel Refai, Olfat A Hassanin
INTRODUCTION: The Goldmann applanation tonometer readings were noted to be markedly reduced after Lasik surgery using a thin flap technique which is widely used nowadays, to correct a wide range of myopia and astigmatism. The Ocular Response Analyzer (ORA) is considered one of the important tools for refinement of Intraocular Pressure (IOP) measurements. The aim of this study is to evaluate and refine ORA measurements for IOP changes post- M2 90 Moria microkeratome Lasik procedure for Egyptian myopic and astigmatic patients trying to aid in glaucoma diagnosis and management...
December 2016: Electronic Physician
https://www.readbyqxmd.com/read/28159503/an-interprofessional-education-workshop-to-develop-health-professional-student-opioid-misuse-knowledge-attitudes-and-skills
#14
Kristina Monteiro, Luba Dumenco, Sally Collins, Jeffrey Bratberg, Celia MacDonnell, Anita Jacobson, Richard Dollase, Paul George
OBJECTIVE: To implement and evaluate an interprofessional workshop focused on increasing student knowledge, skills, and attitudes toward opioid misuse. SETTING: The Warren Alpert Medical School of Brown University in Providence, Rhode Island, April 2016. PRACTICE DESCRIPTION: Health professional students from medicine, nursing, pharmacy, social work, and physical therapy participated in an interprofessional education workshop focused on opioid use disorder...
January 31, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28157808/improved-clinical-performance-and-teamwork-of-pediatric-interprofessional-resuscitation-teams-with-a-simulation-based-educational-intervention
#15
Elaine Gilfoyle, Deanna A Koot, John C Annear, Farhan Bhanji, Adam Cheng, Jonathan P Duff, Vincent J Grant, Cecilia E St George-Hyslop, Nicole J Delaloye, Afrothite Kotsakis, Carolyn D McCoy, Christa E Ramsay, Matthew J Weiss, Ronald D Gottesman
OBJECTIVES: To measure the effect of a 1-day team training course for pediatric interprofessional resuscitation team members on adherence to Pediatric Advanced Life Support guidelines, team efficiency, and teamwork in a simulated clinical environment. DESIGN: Multicenter prospective interventional study. SETTING: Four tertiary-care children's hospitals in Canada from June 2011 to January 2015. SUBJECTS: Interprofessional pediatric resuscitation teams including resident physicians, ICU nurse practitioners, registered nurses, and registered respiratory therapists (n = 300; 51 teams)...
February 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28156535/the-availability-accessibility-gap-of-palliative-care-and-supportive-care-services-at-40-national-cancer-institute-designated-cancer-centers
#16
Geoffrey Hamlyn, Abby Johnston, Rishonda Thomas, James Tian, Arif Kamal
: 122 Background: All NCI-designated, comprehensive cancer centers report having consultative palliative care services alongside six other supportive care services. Inaccuracies in the understanding of these services among frontline office staff may undermine their accessibility to patients. We investigated how easily new patients could access these services when first contacting a major cancer center. METHODS: We used a 'mystery shopper' format to simulate calls made by a family member of a recently diagnosed patient...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28155704/the-movement-and-deposition-of-pm2-5-in-the-upper-respiratory-tract-for-the-patients-with-heart-failure-an-elementary-cfd-study
#17
Tiantian Zhang, Bin Gao, Zhixiang Zhou, Yu Chang
BACKGROUND: PM2.5 is an important factor to affect the patients with respiratory and cardiovascular diseases. Clinical studies have found that the morbidity and mortality of patients with heart failure (HF) have a close relationship with the movement and deposition state of PM2.5. One reason is that the breathing pattern of patients with HF has obvious difference with healthy people, however the effect caused by these differences on the distribution regularity of PM2.5 in the respiratory tract is still unclear...
December 28, 2016: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28155689/the-effect-of-captopril-on-the-performance-of-the-control-strategies-of-bjut-ii-vad
#18
Kaiyun Gu, Bin Gao, Yu Chang, Yi Zeng
BACKGROUND: With the development of left ventricular assist device (LVAD), the long-term support has been paid more attention by various researchers. According to previous researches, the combination of LVAD and pharmacological therapy can significantly improve the heart rate recovery and survival rate of patient. However, the effect of pharmacological therapy on the cardiovascular hemodynamic states with LVAD support is still unclear. METHODS: In this study, pharmacokinetic model of captopril is established to describe the relationship between plasma-drug concentration and time...
December 28, 2016: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28155594/pbpk-modeling-a-predictive-eco-friendly-bio-waiver-tool-for-drug-research
#19
Baishakhi De, Koushik Bhandari, Ranjan Mukherjee, Prakash Katakam, Shanta K Adiki, Rohit Gundamaraju, Analava Mitra
BACKGROUND: The world has witnessed growing complexities in disease scenario influenced by the drastic changes in host-pathogen- environment triadic relation. Pharmaceutical R&Ds are in constant search of novel therapeutic entities to hasten transition of drug molecules from lab bench to patient bedside. Extensive animal studies and human pharmacokinetics are still the "gold standard" in investigational new drug research and bio-equivalency studies. Apart from cost, time and ethical issues on animal experimentation, burning questions arise relating to ecological disturbances, environmental hazards and biodiversity issues...
February 1, 2017: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/28152752/accessibility-and-barriers-to-oncology-appointments-at-40-nci-designated-cancer-centers
#20
Kathryn Hutchins, Abby Johnston, Rishonda Thomas, James Tian, Arif Kamal
: 55 Background: Newly diagnosed cancer patients face fear and uncertainty regarding their prognosis and treatment options. As a first step, these patients and their family members may reach out to top-tier, comprehensive cancer centers for evaluation and treatment; however, recent literature reveals barriers to access. To identify these barriers, we evaluated obstacles patients and caregivers face in accessing services at major cancer centers. METHODS: We used a 'mystery shopper' format to contact 40 NCI-designated, comprehensive cancer centers...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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