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linoleic acid

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https://www.readbyqxmd.com/read/28333826/complex-relation-between-diet-and-phospholipid-fatty-acids-in-children-with-cystic-fibrosis
#1
Sara Moukarzel, Roger A Dyer, Sheila M Innis
OBJECTIVES: Altered total plasma n-6 and n-3 fatty acids are common in cystic fibrosis (CF). Whether alterations extend to plasma phosphatidylcholine (PC) and phosphatidylethanolamine (PE) and are explained by diet is unclear. The present study was to describe the dietary intake of a large group of children with CF and to determine whether dietary fat composition explains differences in plasma PC and PE fatty acids between children with and without CF. METHODS: Dietary intake was assessed using a food frequency questionnaire...
April 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28333262/selection-in-europeans-on-fatty-acid-desaturases-associated-with-dietary-changes
#2
Matthew T Buckley, Fernando Racimo, Morten E Allentoft, Majken K Jensen, Anna Jonsson, Hongyan Huang, Farhad Hormozdiari, Martin Sikora, Davide Marnetto, Eleazar Eskin, Marit E Jørgensen, Niels Grarup, Oluf Pedersen, Torben Hansen, Peter Kraft, Eske Willerslev, Rasmus Nielsen
FADS genes encode fatty acid desaturases that are important for the conversion of short chain polyunsaturated fatty acids (PUFAs) to long chain fatty acids. Prior studies indicate that the FADS genes have been subjected to strong positive selection in Africa, South Asia, Greenland, and Europe. By comparing FADS sequencing data from present-day and Bronze Age (5-3k years ago) Europeans, we identify possible targets of selection in the European population, which suggest that selection has targeted different alleles in the FADS genes in Europe than it has in South Asia or Greenland...
March 16, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28330183/purification-and-characterization-of-lipoxygenase-from-mung-bean-vigna-radiata-l-germinating-seedlings
#3
Raveendra Aanangi, Kasi Viswanath Kotapati, Bhagath Kumar Palaka, Thyagaraju Kedam, Nirmala Devi Kanika, Dinakara Rao Ampasala
This study reports purification and characterization of lipoxygenase protein from mung bean germinating seedlings. Lipoxygenases (LOXs) are key enzymes in seed germination. The purified mung bean LOX has resolved into two peaks by chromatofocusing, one has highest LOX activity with an isoelectric point of 5.84 and the other has lowest LOX activity with an isoelectric point of 5.52. The purified LOX has molecular mass of approximately 97 kDa and showed high activity with linoleic acid than linolenic acid and arachidonic acid...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330161/in-vitro-propagation-carotenoid-fatty-acid-and-tocopherol-content-of-ajuga-multiflora-bunge
#4
Iyyakkannu Sivanesan, Ramesh Kumar Saini, Rafi Noorzai, Ahmad Jawid Zamany, Doo Hwan Kim
The effect of plant growth regulators on shoot proliferation from shoot tip explants of Ajuga multiflora was studied. The highest number of shoots (17.1) was observed when shoot tip explants were cultured on Murashige and Skoog (MS) medium fortified with 8.0 µM 6-Benzyladenine (BA) and 2.7 µM α-naphthaleneacetic acid (NAA). The mean number of shoots per explant was increased 1.6-fold in liquid medium as compared with semi-solid medium. Maximum rooting (100 %) with an average of 7.2 roots per shoot was obtained on MS basal medium...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28330160/characterization-of-cla-producing-butyrivibrio-spp-reveals-strain-specific-variations
#5
S K Asraf Hussain, Anima Srivastava, Ashish Tyagi, Umesh Kumar Shandilya, Ashwani Kumar, Sachin Kumar, Surbhi Panwar, Amrish Kumar Tyagi
Conjugated Linoleic Acid (CLA), a fatty acid with high nutraceutical value is produced in rumen by resident bacterial species, especially Butyrivibrio spp. The present study was undertaken to examine the diversity of indigenous Butyrivibrio spp. from rumen liquor of Indian ruminants. The isolates were screened for their CLA production capability at different level of linoleic acid (LA) (0, 200, 400, 600, 800 μg/ml) at different time intervals (0, 2, 4, 6, 12, and 24 h). A total of more than 300 anaerobic cultures were isolated and 31 of them were identified as Butyrivibrio spp...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28325998/glucomannan-and-glucomannan-plus-spirulina-enriched-pork-affect-liver-fatty-acid-profile-ldl-receptor-expression-and-antioxidant-status-in-zucker-fa-fa-rats-fed-atherogenic-diets
#6
Laura González-Torres, Cátia Matos, Miguel Vázquez-Velasco, Jorge A Santos-López, Iria Sánchez-Martínez, Camino García-Fernández, Sara Bastida, Juana Benedí, Francisco J Sánchez-Muniz
We evaluated the effects of glucomannan or glucomannan plus spirulina-restructured pork (RP) on liver fatty acid profile, desaturase/elongase enzyme activities and oxidative status of Zucker fa/fa rats for seven weeks. Control (C), glucomannan (G) and glucomannan/spirulina (GS)-RP; HC (cholesterol-enriched control), HG and HGS (cholesterol-enriched glucomannan and glucomannan/spirulina-RP) experimental diets were tested. Increased metabolic syndrome markers were found in C, G and GS rats. Cholesterol feeding increased liver size, fat, and cholesterol and reduced antioxidant enzyme levels and expressions...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28324165/lipid-phenol-and-carotenoid-changes-in-bianca-grapevine-leaves-after-mechanical-wounding-a-case-study
#7
Giulia Chitarrini, Luca Zulini, Domenico Masuero, Urska Vrhovsek
Metabolic changes can occur in plants in response to abiotic stress. Extensive use of leaf discs (mechanical wounding) in studies regarding the effect on the biochemical response of the grapevine to different types of biotic stress makes it necessary to understand metabolic perturbation after injury. In this study, we investigate how mechanical wounding can affect the metabolism of grapevine leaf tissue using Bianca variety as case study. Two sizes of leaf discs (1.1 and 2.8 cm in diameter) were excised from leaves, and phenol, lipid and carotenoid perturbation were investigated 0, 6, 12, 24, 48, 96 and 120 h post cutting...
March 21, 2017: Protoplasma
https://www.readbyqxmd.com/read/28324158/the-influence-of-sex-and-diet-on-the-characteristics-of-hibernation-in-syrian-hamsters
#8
Marie Trefna, Maaike Goris, Cynthia M C Thissen, Vera A Reitsema, Jojanneke J Bruintjes, Edwin L de Vrij, Hjalmar R Bouma, Ate S Boerema, Robert H Henning
Research on deep hibernators almost exclusively uses species captured from the wild or from local breeding. An exception is Syrian hamster (Mesocricetus auratus), the only standard laboratory animal showing deep hibernation. In deep hibernators, several factors influence hibernation quality, including body mass, sex and diet. We examined hibernation quality in commercially obtained Syrian hamsters in relation to body mass, sex and a diet enriched in polyunsaturated fatty acids. Animals (M/F:30/30, 12 weeks of age) were obtained from Harlan (IN, USA) and individually housed at 21 °C and L:D 14:10 until 20 weeks of age, followed by L:D 8:16 until 27 weeks...
March 21, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28323825/association-between-fatty-acid-metabolism-in-the-brain-and-alzheimer-disease-neuropathology-and-cognitive-performance-a-nontargeted-metabolomic-study
#9
Stuart G Snowden, Amera A Ebshiana, Abdul Hye, Yang An, Olga Pletnikova, Richard O'Brien, John Troncoso, Cristina Legido-Quigley, Madhav Thambisetty
BACKGROUND: The metabolic basis of Alzheimer disease (AD) pathology and expression of AD symptoms is poorly understood. Omega-3 and -6 fatty acids have previously been linked to both protective and pathogenic effects in AD. However, to date little is known about how the abundance of these species is affected by differing levels of disease pathology in the brain. METHODS AND FINDINGS: We performed metabolic profiling on brain tissue samples from 43 individuals ranging in age from 57 to 95 y old who were stratified into three groups: AD (N = 14), controls (N = 14) and "asymptomatic Alzheimer's disease" (ASYMAD), i...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28323626/pomegranate-punica-granatum-seed-oil-for-treating-menopausal-symptoms-an-individually-controlled-cohort-study
#10
Roman Huber, Richard Gminski, Tao Tang, Tomas Weinert, Sabine Schulz, Margareta Linke-Cordes, Ines Martin, Heide Fischer
Context • In the folk medicine of Mediterranean countries and in ancient Ayurveda, Punica granatum seeds (ie, pomegranate seeds) have been used for treatment of various disorders, including those that nowadays are classified as menopausal symptoms (MSs). Pomegranate seed oil (PSO) from those seeds mainly contains unsaturated fatty acids such as γ-linoleic acid and linolenic acid, but it also includes phytoestrogens. It is, therefore, regarded as a promising option for treating MSs today. Objectives • The study intended to investigate the safety and effectiveness of PSO as a defined P granatum seed oil for patients with MSs...
March 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28319414/preparation-and-characterization-of-zno-nanoparticles-coated-by-chitosan-linoleic-acid-fungal-growth-and-biofilm-assay
#11
S Barad, M Roudbary, A Nasrollahi Omran, M Porgham Daryasari
INTRODUCTION: This study has been carried out on reviewing the use of new synthetic component of zinc oxide nanoparticles (ZnO NPs) coated by Chitosan-linoleic acid (CS-LA) and to assess Minimum inhibitory concentration (MIC) of nanoparticles on clinical samples and biofilm formation in vitro. MATERIALS AND METHODS: At first the synthesized ZnO NPs coated by CS-LA were identified with X-ray powder diffraction (XRD), Scanning electron microscope (SEM), Transmission electron microscope (TEM) and Fourier Transform Infrared Spectroscopy analysis (FTIR)...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28318463/decreasing-the-overall-environmental-impact-of-the-dutch-diet-how-to-find-healthy-and-sustainable-diets-with-limited-changes
#12
Gerard Fh Kramer, Marcelo Tyszler, Pieter Van't Veer, Hans Blonk
OBJECTIVE: To find diets optimised on nutrition and environmental impact close to the current Dutch diet and to identify the most effective and acceptable options for mitigating environmental impact. DESIGN: Linear programming was used to optimise diets of Dutch men and women aged 9-69 years, divided into ten age-gender groups. The analysis included nutrient composition, a metric for popularity and life cycle assessments of 207 food products. Greenhouse gas emissions, fossil energy use and land occupation were used to calculate a weighted score for the overall environmental impact...
March 20, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28317745/the-impact-of-rhizopus-oryzae-cultivation-on-rice-bran-gamma-oryzanol-recovery-and-its-antioxidant-properties
#13
Kelly Cristina Massarolo, Taiana Denardi de Souza, Carolina Carvalho Collazzo, Eliana Badiale Furlong, Leonor Almeida de Souza Soares
This study evaluated the effect of the solid state cultivation (SSC) time of rice bran by Rhizopus oryzae on γ-oryzanol recovery and its antioxidant properties. Gamma-oryzanol was extracted with organic solvents and its extracts were characterized by GC-FID and HPLC-UV. The antioxidant capacity was assessed by DPPH and ABTS(+) assays, β-carotene/linoleic acid system, and reduction of oxidation in lipid system. The biomass showed the γ-oryzanol recovery increased by 51.5% (20.52mg/g), and 5.7% in polyunsaturated fatty acids...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317740/physicochemical-and-thermal-characteristics-of-australian-chia-seed-oil
#14
Yakindra Prasad Timilsena, Jitraporn Vongsvivut, Raju Adhikari, Benu Adhikari
Physicochemical and thermal characteristics of Australian chia seed oil (CSO) were studied. The specific gravity, viscosity and refractive index of CSO at ambient temperature were 0.93, 43.2mPa.s and 1.48, respectively. The acid, peroxide, saponification and iodine values and unsaponifiable matter content of CSO were 2.54gKOH/kg oil, 4.33meqO2/kg oil, 197gKOH/kg oil, 204gI2/kg oil and 1.12%, respectively. α-linolenic acid is the most abundant fatty acid comprising (64.39% of total oil) followed by linoleic acid (21...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28316633/medicinal-plants-from-northeastern-brazil-against-alzheimer-s-disease
#15
Alexandre Batista Penido, Selene Maia De Morais, Alan Bezerra Ribeiro, Daniela Ribeiro Alves, Ana Livya Moreira Rodrigues, Leonardo Hunaldo Dos Santos, Jane Eire Silva Alencar de Menezes
Alzheimer's disease (AD) has been linked with oxidative stress, acetylcholine deficiency in the brain, and inflammatory processes. In the northeast region of Brazil, various plants are used to treat several diseases associated with these processes; then an antioxidant test was performed with those plants in a previous work and twelve species with higher antioxidant activity were selected for AChE inhibition evaluation. The phenolic compounds content was determined by Folin-Ciocalteu test and flavonoid content with AlCl3 reagent using UV-visible spectrophotometry...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28316626/evaluation-of-phenolic-compounds-and-antioxidant-and-antimicrobial-activities-of-some-common-herbs
#16
Muhammad Abdul Qadir, Syeda Kiran Shahzadi, Asad Bashir, Adil Munir, Shabnam Shahzad
The study was designed to evaluate the phenolic, flavonoid contents and antioxidant and antimicrobial activities of onion (Allium cepa), garlic (Allium sativum), mint (Mentha spicata), thyme (Thymus vulgaris), oak (Quercus), aloe vera (Aloe barbadensis Miller), and ginger (Zingiber officinale). All extracts showed a wide range of total phenolic contents, that is, 4.96 to 98.37 mg/100 g gallic acid equivalents, and total flavonoid contents, that is, 0.41 to 17.64 mg/100 g catechin equivalents. Antioxidant activity (AA) was determined by measuring reducing power, inhibition of peroxidation using linoleic acid system, and 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging activity...
2017: International Journal of Analytical Chemistry
https://www.readbyqxmd.com/read/28316467/changes-in-the-total-lipid-neutral-lipid-phospholipid-and-fatty-acid-composition-of-phospholipid-fractions-during-past%C3%A4-rma-processing-a-dry-cured-meat-product
#17
Muhammet Irfan Aksu, Mehmet Dogan, Ahmet Necdet Sirkecioglu
Pastırma is a dry-cured meat product, produced from whole beef or water buffalo muscles. This study was carried out to investigate the effect of production stages (raw meat, after curing, after 2(nd) drying and pastırma) on the total lipid, neutral lipid, phospholipid and fatty acid composition of phospholipid fraction of pastırma produced from beef M. Longissimus dorsi muscles. The pH and colour (L*, a* and b*) analyses were also performed in raw meat and pastırma. It was found that pastırma production stages had significant effects (p<0...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/28306206/phytochemical-profile-and-biological-activities-of-helianthemum-canum-from-turkey
#18
Ayşe Baldemir, Neslihan Gökşen, Nilay Ildız, Gökçe Şeker Karatoprak, Müberra Koşar
In the current study, antioxidant, antibacterial activities, and the phenolic compositions of extracts from Helianthemum canum L. Baumg (Apiaceae) aerial parts were investigated for the first time. The H. canum was extracted with 70% methanol (HCMeOH) and water (HCW). Both extracts were determined by total phenolic contents (3 mg/mL), flavonoids (1.5 mg/mL), flavonols (1.5 mg/mL), qualitative-quantitative compositions, iron (II) chelation activities (0.1-5 mg/mL), free radical scavenging activities (DPPH(●) : 0...
March 17, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28303360/modulation-of-linoleic-acid-binding-properties-of-human-serum-albumin-by-divalent-metal-cations
#19
Ekaterina L Nemashkalova, Eugene A Permyakov, Sergei E Permyakov, Ekaterina A Litus
Human serum albumin (HSA) is an abundant multiligand carrier protein, linked to progression of Alzheimer's disease (AD). Blood HSA serves as a depot of amyloid β (Aβ) peptide. Aβ peptide-buffering properties of HSA depend on interaction with its ligands. Some of the ligands, namely, linoleic acid (LA), zinc and copper ions are involved into AD progression. To clarify the interplay between LA and metal ion binding to HSA, the dependence of LA binding to HSA on Zn(2+), Cu(2+), Mg(2+) and Ca(2+) levels and structural consequences of these interactions have been explored...
March 16, 2017: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/28303042/effect-of-dehulling-germination-and-cooking-on-nutrients-anti-nutrients-fatty-acid-composition-and-antioxidant-properties-in-lentil-lens-culinaris
#20
R S Pal, Anuradha Bhartiya, Pradhuman Yadav, Lakshmi Kant, K K Mishra, J P Aditya, A Pattanayak
The changes in chemical composition, antioxidant activity and fatty acid composition of lentil flour after dehulling, germination and cooking of seeds were investigated. Dehulling showed no significant effect on protein content, however, protein content decreased in most of the varieties after germination and cooking. Total soluble sugars (TSS) content increased significantly after dehulling (2.0-41.64 %) and cooking (2.08-31.07 %) whereas, germination had no significant effect on TSS content. Total lipids increased significantly after dehulling (21...
March 2017: Journal of Food Science and Technology
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