Read by QxMD icon Read


José Humberto Bravo, Andrés Mauricio Agudelo, Armando Cortés, Lorena Matta
Rhino-orbito-cerebral mucormycosis from dental origin is an acute infection caused by opportunistic fungi belonging to the order of Mucorales, which affects mainly diabetic and immunocompromised patients.We report the case of a 63-year old diabetic man who performed a dental extraction on himself by his own means and subsequently developed a rhino-orbito-cerebral mucormycosis with cutaneous and palatal affection. The species isolated in the mycological culture was Rhizopus sp.
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
Fedja I Vos, Sietze Reitsma, Gwijde F J P M Adriaensen, Wytske J Fokkens
In this report, we describe the case of a young, diabetic girl with ketoacidosis who suffered sudden loss of vision of the right eye. The loss of vision was caused by an invasive rhino-orbital-cerebral fungal infection (mucormycosis) with extensive periorbital thrombosis. Despite maximal antifungal and surgical treatment (including exenteration of the right orbit), the clinical situation deteriorated. It was only after overcoming the difficulties of managing her hyperglycaemia that the patient's condition stabilised and her life was saved...
April 17, 2018: BMJ Case Reports
Peyman Mahmoodi, Keikhosro Karimi, Mohammad J Taherzadeh
Organic fraction of municipal solid waste (OFMSW) is dominated by carbohydrates, including starch-based and lignocellulosic materials. The OFMSW was hydrothermally pretreated at 100-160 °C for 0-60 min, and then assessed for enzymatic ethanol production, followed by biogas production from the stillage. The highest glucose yield of 520 g/Kg of dry OFMSW, corresponding to 131% increase compared to that of the untreated OFMSW, was obtained after the pretreatment and enzymatic hydrolysis. Through ethanolic fermentation by an inhibitory tolerant fungus, Mucor indicus, 191...
April 6, 2018: Bioresource Technology
Brandon T Nokes, Octavio Pajaro, Jenise Stephen, Patrick DeValeria, Robert Scott, Sadia Shah, Eric Steidley, Jama Jahanyar
Invasive mucormycosis infections occur in less than 1% of recipients of orthotopic heart transplants. Given the angioinvasive nature of these infections, the mortality rate is high. Little literature exists regarding the presentation and management of these infections. We present a case of a patient who developed an infection after orthotopic heart transplant, describe the successful multidisciplinary management surrounding his care, and review the available literature regarding mucormycosis infections in heart transplant recipients...
March 5, 2018: Heart Surgery Forum
Danielle N Atwood, Pallavi A Kumbla, Brian Yuen, James C Yuen
Mucormycosis has a mortality rate reaching 90%, and is imperative that therapy be initiated rapidly once a diagnosis is made. Successful treatment consists of management of underlying risk factors, surgical debridement, and antifungal therapies. The dilemma whether or not to pursue extensive debridement presents when the wound is cultured positive but the patient is not systemically ill. We present the first reported case of successful medical treatment of a seroma pocket colonized with mucor in a patient undergoing bilateral reconstruction with tissue expander and acellular dermal matrix...
January 2018: World Journal of Plastic Surgery
José Ángel Hernández, Rita Sánchez-Andrade, Cristiana Filipa Cazapal-Monteiro, Fabián Leonardo Arroyo, Jaime Manuel Sanchís, Adolfo Paz-Silva, María Sol Arias
BACKGROUND: An approach to preventing strongyle infection in horses was tested, comprising rotational pasturing and the administration of spores of two parasiticidal fungi, Mucor circinelloides and Duddingtonia flagrans. METHODS: Twenty-two adult Spanish Sport Horses were dewormed with ivermectin (1 mg pour-on/kg body weight) and then randomly divided into three groups. G-1 was maintained with continuous grazing, and G-2 and G-3 were kept on a four-paddock rotation system...
April 12, 2018: Parasites & Vectors
Yeong Hun Choe, Yong Chul Lee, So Ri Kim
No abstract text is available yet for this article.
April 12, 2018: American Journal of Respiratory and Critical Care Medicine
Gergely Kosa, Kiira S Vuoristo, Svein Jarle Horn, Boris Zimmermann, Nils Kristian Afseth, Achim Kohler, Volha Shapaval
Recent developments in molecular biology and metabolic engineering have resulted in a large increase in the number of strains that need to be tested, positioning high-throughput screening of microorganisms as an important step in bioprocess development. Scalability is crucial for performing reliable screening of microorganisms. Most of the scalability studies from microplate screening systems to controlled stirred-tank bioreactors have been performed so far with unicellular microorganisms. We have compared cultivation of industrially relevant oleaginous filamentous fungi and microalga in a Duetz-microtiter plate system to benchtop and pre-pilot bioreactors...
April 11, 2018: Applied Microbiology and Biotechnology
Yaqiong Wang, Biswarup Sen, Yaodong He, Ningdong Xie, Guangyi Wang
Fungi play a critical role in the nutrient cycling and ecological function in terrestrial and freshwater ecosystems. Yet, many ecological aspects of their counterparts in coastal ecosystems remain largely elusive. Using high-throughput sequencing, quantitative PCR, and environmental data analyses, we studied the spatiotemporal changes in the abundance and diversity of planktonic fungi and their abiotic and biotic interactions in the coastal waters of three transects along the Bohai Sea. A total of 4362 ITS OTUs were identified and more than 60% of which were unclassified Fungi...
2018: Frontiers in Microbiology
Jagdish Chander, Mandeep Kaur, Nidhi Singla, R P S Punia, Surinder K Singhal, Ashok K Attri, Ana Alastruey-Izquierdo, Alberto M Stchigel, Jose F Cano-Lira, Josep Guarro
Mucormycosis is an emerging opportunistic fungal infection. Increasing immunocompromization, widespread use of antibacterial and antifungal agents (such as voriconazole prophylaxis), carcinomas, transplantation and lifestyle diseases such as diabetes are the main contributors to this situation. The predominant clinical manifestations of mucormycosis vary from host to host, with rhino-orbital-cerebral, pulmonary, cutaneous, and gastrointestinal infections being the most common. In India, the prevalence of mucormycosis is approximately 0...
April 6, 2018: Journal of Fungi (Basel, Switzerland)
Saira Ajmal, Maryam Mahmood, Omar Abu Saleh, Jenifer Larson, M Rizwan Sohail
BACKGROUND: Increased risk of invasive pulmonary aspergillosis after influenza infection has been reported; however data are limited. PURPOSE: To describe Invasive fungal infections (IFI) associated with preceding respiratory viral infection at a large referral center. METHODS: We reviewed all IFI cases among patients with positive influenza and/or RSV nasopharyngeal/lower respiratory tract PCR from October 2015 to December 2016. Cases of pulmonary IFI were classified as possible, probable, and definite based on EORTC-MSG definitions...
April 7, 2018: Infection
Katarzyna Wolny-Koładka
The aim of this study was to assess the microbiological quality of air in three horse riding centers differing in the horse keeping systems. The air samples were collected in one facility with free-range horse keeping system and two with box stalls of different sizes. The samples were collected over a period of 3 years (2015-2017), four times per year (spring, summer, autumn, winter) to assess the effect of seasonal changes. The prevalence of aerobic mesophilic bacteria, mold fungi, actinomycetes, Staphylococcus spp...
April 7, 2018: Environmental Monitoring and Assessment
Guangzhi Li, Junchi Wang, Xiaojin Li, Jianguo Xu, Zhao Zhang, Jianyong Si
2'-Z auraptene (1) is a synthesized monoterpene coumarin with anticancer activity against human gastric cancer cells. In order to find new potential anticancer agent, Mucor polymorphosporus was used to transform cis-auraptene. Four new terpene coumarins with notable changes in the skeletal backbone, 2'-Z auraptene A-D (2-5), were obtained and evaluated for their antiproliferative effects against human normal gastric epithelium cells and human gastric cancer cells. These new compounds showed selective cytotoxic activity against MGC-803 cells with IC50 values from 0...
April 4, 2018: Archives of Pharmacal Research
Piotr Rozpądek, Agnieszka M Domka, Michał Nosek, Rafał Ważny, Roman J Jędrzejczyk, Monika Wiciarz, Katarzyna Turnau
Over the last years the role of fungal endophytes in plant biology has been extensively studied. A number of species were shown to positively affect plant growth and fitness, thus attempts have been made to utilize these microorganisms in agriculture and phytoremediation. Plant-fungi symbiosis requires multiple metabolic adjustments of both of the interacting organisms. The mechanisms of these adaptations are mostly unknown, however, plant hormones seem to play a central role in this process. The plant hormone strigolactone (SL) was previously shown to activate hyphae branching of mycorrhizal fungi and to negatively affect pathogenic fungi growth...
2018: Frontiers in Microbiology
Xu Zhang, Xinxin Li, Huanhuan Yang, Zhaojie Cui
This study focused on the bioremediation mechanisms of lead (0, 100, 500, 1000 mg kg-1 ) and cadmium (0,10,50,100 mg kg-1 ) contaminated soil using two indigenous fungi selected from mine tailings as the phytostimulation of Arabidopsis thaliana. The two fungal strains were characterized as Mucor circinelloides (MC) and Trichoderma asperellum (TA) by internal transcribed spacer sequencing at the genetic levels. Our research revealed that Cadmium was more toxic to plant growth than lead and meanwhile, MC and TA can strengthen A...
March 29, 2018: Ecotoxicology and Environmental Safety
Lucille Garnier, Marcia Leyva Salas, Nicolas Pinon, Norman Wiernasz, Audrey Pawtowski, Emmanuel Coton, Jérôme Mounier, Florence Valence
In this study, we developed a high-throughput antifungal activity screening method using a cheese-mimicking matrix distributed in 24-well plates. This method allowed rapid screening of a large variety of antifungal agent candidates: bacterial fermented ingredients, bacterial isolates, and preservatives. Using the proposed method, we characterized the antifungal activity of 44 lactic acid bacteria (LAB) fermented milk-based ingredients and 23 LAB isolates used as protective cultures against 4 fungal targets (Mucor racemosus, Penicillium commune, Galactomyces geotrichum, and Yarrowia lipolytica)...
March 28, 2018: Journal of Dairy Science
A-A H Moubasher, M A Abdel-Sater, Z S M Soliman
This work aimed to identify and evaluate the diversity of yeasts and filamentous fungi that contaminate some dairy products (fresh buffalo milk, plain yoghurt, butter and Kareisk cheese) in Assiut city, Egypt. The identification was based on phenotypic characteristics, and genotypically in case of yeasts. The pHs of all dairy products lie within the acidic range, but yoghurt registered the highest value. A total of 41 genera and 89 species+3 varieties were recovered from all dairy products investigated on DRBC (26 genera representing 59 species+1 variety), DG18 (32 genera, 56 species+2 varieties) and MY50G (31 genera, 64 species+2 varieties)...
March 27, 2018: Journal de Mycologie Médicale
Benjamin M Marsh, Radha Rajasingham, Sherif H Tawfic, Michael S Borofsky
No abstract text is available yet for this article.
March 27, 2018: Urology
Muxing Liu, Gillian O Bruni, Christopher M Taylor, Zhengguang Zhang, Ping Wang
Rhizopus delemar is an emerging fungal pathogen causing devastating mucormycosis in immunocompromised individuals. The organism remains understudied and there are urgent needs for new methods of rapid disease diagnosis for timely therapy. Extracellular vesicles with encapsulated RNAs have recently been discovered to have great potential applications for disease diagnoses and treatments. To explore the utilization of ex-RNA in studies of mucormycosis, we have performed RNA-Seq of ex-sRNAs from two clinical strains of R...
March 27, 2018: Scientific Reports
Sarah Inglesfield, Aleksandra Jasiulewicz, Matthew Hopwood, James Tyrrell, George Youlden, Maria Mazon-Moya, Owain R Millington, Serge Mostowy, Sara Jabbari, Kerstin Voelz
Mucormycosis is an emerging fungal infection with extremely high mortality rates in patients with defects in their innate immune response, specifically in functions mediated through phagocytes. However, we currently have a limited understanding of the molecular and cellular interactions between these innate immune effectors and mucormycete spores during the early immune response. Here, the early events of innate immune recruitment in response to infection by Mucor circinelloides spores are modeled by a combined in silico modeling approach and real-time in vivo microscopy...
March 27, 2018: MBio
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"