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https://www.readbyqxmd.com/read/28426905/acantholytic-dyskeratotic-acanthoma-a-possible-skin-adverse-event-of-vemurafenib-treatment
#1
Takaya Komori, Atsushi Otsuka, Yo Kaku, Tetsuya Honda, Kenji Kabashima
Acantholytic dyskeratotic acanthoma (ADA) is a solitary small papule that is pathologically characterized by dyskeratosis with acantholytic acanthosis (1). Vemulafenib is a specific inhibitor of BRAF protein kinase with V600E mutation and is administered to treat metastatic melanoma. Various skin adverse events associated with vemurafenib, including acantholysis and flare up of Darier's disease, have been reported (2, 3). Here we report a case of ADA that developed during vemulafenib treatment for metastatic melanoma...
April 20, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28426489/a-large-congenital-blue-plaque-with-papules-and-nodules-on-the-lower-back
#2
Courtney B Rubin, Andrea Boni, Rosalie Elenitsas, Jennifer Pogoriler, David Low, Adam I Rubin
No abstract text is available yet for this article.
May 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28426487/brief-report-hpv-17-infection-in-darier-disease-with-acrokeratosis-verrucosis-of-hopf
#3
Andrew Matsumoto, Neal Gregory, Peter L Rady, Stephen K Tyring, John A Carlson
The co-existence of Darier disease (DD) and acrokeratosis verruciformis of Hopf (AKV) has been noted for decades and the relationship between the 2 entities remains controversial. Although, it has been shown that both diseases are associated with mutations in ATPA2 gene, it is yet to be determined if they are the same disease, or separate but allelic, or interlinked in some other fashion. Herein, the authors report the case of a 13-year-old girl presenting with shiny flat-topped verruca plana-like papules, on the dorsal hands and feet and red-brown crusted papules on her forehead and along the sides of her neck...
May 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28421227/multiple-fine-firm-keratotic-papules-on-the-palms-a-quiz
#4
Aline Schöller, Cyrill Géraud
No abstract text is available yet for this article.
April 19, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28421149/eccrine-nevus-presenting-with-umbilical-discharge-a-case-report-and-review-of-the-literature
#5
Farahnaz Bidari-Zerehpoosh, Shahram Sabeti, Farid Arman, Hania Shakeri
Eccrine nevus is a rare skin lesion with protean manifestations like hyperhidrosis, discolored nodules, papules, and so forth, which has been reported in various anatomic parts of the body including the forearm, leg, thigh, back, and coccyx. Our patient was a 26-year-old male, who presented with increasing colorless and odorless episodic umbilical discharge. First impression for the patient was an umbilical sinus and the patient underwent surgery. Histopathological study revealed the lesion to be an eccrine nevus of the umbilicus...
2017: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/28418344/rare-giant-angiokeratoma-of-the-vulva-a-case-report
#6
Fatih Doğan, İbrahim Hakan Bucak
BACKGROUND: Angiokeratoma of fordyce occurring over on the vulva is a rare condition. Fordyce angiokeratoma is observed more frequently among men than women. In women, it is generally observed in later life, and appears as multiple dark purple papules, measuring 2-4 mm, on the vulva. CASE REPORT: We present the case of a 17-year-old white teenage girl with giant Fordyce angiokeratoma on the right vulva. The angiokeratoma was removed and a V-Y advancement flap was made...
April 5, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28413505/rare-scar-sarcoidosis-a-case-report
#7
Sha Zhao, Qin Wang, Beibei Cheng, Xiao-Fang Zhu
A 70-year-old female patient presenting with swelling and subcutaneous nodule formation localized to the knee scars over a two-month period is presently reported. Dermatological examinations found erythematous swelling and small papules on the patient's knee scars, along with subcutaneous nodules beneath and around the scars. Computer tomography of the chest region identified multiple obscure tubercles in the lungs and swollen lymph nodes in the hilum pulmonis and mediastinum. Skin biopsy revealed multiple non-caseating granulomas, which had infiltrated the dermis...
April 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28411784/asymptomatic-papules-after-breast-cancer-treatment
#8
Gordon H Bae, Drew Kurtzman, Scott R Granter, Ruth Ann Vleugels, Vinod E Nambudiri
No abstract text is available yet for this article.
May 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28407871/acral-hemorrhagic-darier-disease
#9
M Á Flores-Terry, M García-Arpa, M Llamas-Velasco, C Mendoza-Chaparro, C Ramos-Rodríguez
Darier disease is an autosomal-dominant inherited condition caused by mutation of a gene, which produces a protein involved in calcium channel regulation. The disease has a variety of manifestations and lacks consistent genotype-phenotype correlations. Acral hemorrhagic Darier disease causes macules, papules, vesicles and/or hemorrhagic blisters on the extremities. Other classic signs of the disease may be present in the same patient or relatives. Histopathology reveals dyskeratosis and suprabasal acantholysis with hemorrhagic lacunae...
April 10, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28405567/skindia-quiz-35-a-girl-with-multiple-papules
#10
Siddhi Gaurish Sinai Khandeparkar, Maithili M Kulkarni, Sanjay Deshmukh, Yuvraj E More
No abstract text is available yet for this article.
March 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28404554/oesophageal-eosinophilia-in-children-with-coeliac-disease
#11
Anne Ari, Sara Morgenstern, Gabriel Chodick, Manar Matar, Ari Silbermintz, Amit Assa, Yael Mozer-Glassberg, Firas Rinawi, Vered Nachmias-Friedler, Raanan Shamir, Noam Zevit
OBJECTIVES: An association between coeliac disease (CD) and eosinophilic oesophagitis (EoE)/oesophageal eosinophilia (EE) has been suggested. We sought to characterise children with CD+EE in-depth and assess the contribution of each condition to the clinical presentation and treatment response. STUDY DESIGN: Medical records of children with both CD+EE, or isolated EoE diagnosed between 2000 and 2014, were retrospectively reviewed and compared with patients with isolated CD or epigastric pain...
April 12, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28403376/eruption-of-yellow-brown-and-red-brown-papules-in-a-young-adult-with-polydipsia-and-polyuria
#12
Jessica M Donigan, Zachary N Collins, David A Wada
No abstract text is available yet for this article.
April 12, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28398921/hemosiderotic-juvenile-xanthogranuloma
#13
Angel Fernandez-Flores, Ina Nicklaus, Fiona Browne, Isabel Colmenero
Juvenile xanthogranuloma is a non-Langerhans cell lesion mostly limited to the skin but occasionally presenting in extracutaneous locations or associated with systemic conditions. Lesions need to be distinguished mainly from dermatofibroma, xanthoma, Langerhans cell histiocytosis, or reticulohistiocytoma. Herein, we present a hemosiderotic variant of juvenile xanthogranuloma in a 12-year-old girl, which we have not found described in literature. The lesion presented at the back of the scalp as a slowly growing yellowish polypoid lesion showing occasional bleeding...
March 16, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28398427/disseminated-superficial-actinic-porokeratosis-treated-with-ingenol-mebutate-gel-0-05
#14
Isabella Anderson, Ethan T Routt, Shelbi C Jim On
Disseminated superficial actinic porokeratosis (DSAP) is a chronic condition characterized by numerous atrophic papules and patches with a distinctive peripheral keratotic ridge, typically found on sun-exposed areas. Treatment of DSAP is warranted not only for cosmetic and symptomatic benefits but also to prevent malignant transformation. Successful treatment of DSAP often is difficult and frequently requires the use of multiple modalities. Ingenol mebutate gel 0.05% is a topical medication primarily used for the treatment of actinic keratosis (AK) by inducing cell death...
March 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28398418/erythematous-pearly-papule-on-the-chest
#15
Nikoleta Brankov, Amandeep Sandhu, Justin Kerstetter, Nancy Anderson
No abstract text is available yet for this article.
March 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28397724/drug-reaction-with-eosinophilia-and-systemic-symptoms-retrospective-analysis-of-104-cases-over-one-decade
#16
Li Wang, Xue-Ling Mei
BACKGROUND: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe, life-threatening disorder caused by drugs. In the present study, we tried to explore the types of DRESS-inducing drugs, incubation period, features of skin rashes, accompanying visceral damage, and effectiveness of glucocorticoid therapy so as to inform clinical practice. METHODS: Patients diagnosed with a drug-induced rash, dermatitis, and DRESS admitted to our hospital from January 2006 to December 2015 were included in the study...
April 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28394969/-confluent-and-reticulated-papillomatosis-subsiding-spontaneously-after-delivery-report-of-one-case
#17
Jinan A R Usta, Samer Ghosn, Malak H Wehbe
Gougerot and Carteaud confluent and reticulated papillomatosis (CARP) is an uncommon dermatosis characterized by hyperpigmented scaly macules or papillomatous papules coalescing into confluent patches or plaques centrally with a reticular pattern peripherally. We report a 28-year-old woman presenting at 16 weeks of gestation with an itchy rash that was biopsied and turned out to be consistent with CARP. Options for treatment were discussed but the woman refused to take any systemic therapy and used only moisturizers throughout her pregnancy...
November 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28392652/paraneoplastic-pemphigus-associated-with-a-malignant-thymoma-a-case-of-persistent-and-refractory-oral-ulcerations-following-thymectomy
#18
Jung Min Lim, Sang Eun Lee, Jimyung Seo, Do Young Kim, Takashi Hashimoto, Soo-Chan Kim
Paraneoplastic pemphigus is a rare, life-threatening autoimmune mucocutaneous blistering disease associated with underlying neoplasia, commonly lymphoproliferative tumors. Herein we report a case of paraneoplastic pemphigus with a unique autoantibody profile associated with a malignant thymoma. A 56-year-old female patient presented with relapsing oral ulcerations accompanied by erythematous papules and patches on her extremities for 2 months. Skin and mucosal biopsies identified interface dermatitis with lichenoid lymphocytic infiltration in the upper dermis...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28392640/urticarial-dermatitis-clinical-characteristics-of-itch-and-therapeutic-response-to-cyclosporine
#19
Jeong-Min Kim, Kyung-Min Lim, Hoon-Soo Kim, Hyun-Chang Ko, Moon-Bum Kim, Byung-Soo Kim
BACKGROUND: Urticarial dermatitis, which is characterised by persistent wheals with eczematous papules and plaques, is frequently misdiagnosed and difficult to treat. Patients commonly experience intolerable pruritus which may greatly affect their quality of life. OBJECTIVE: The objective of this study is to characterize the clinical patterns of pruritus in patients with urticarial dermatitis and to determine the effectiveness of cyclosporine treatment. METHODS: This prospective study included 50 histopathologically confirmed patients with urticarial dermatitis...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28387993/multiple-yellowish-papules-on-the-labia-majora
#20
Ricardo Ruiz-Villaverde, Cristina Garrido-Colmenero, Miguel Antonio Díaz-Martinez, Jose Aneiros-Fernandez
No abstract text is available yet for this article.
April 7, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
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