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https://www.readbyqxmd.com/read/28938368/reply-the-split-pectoralis-flap-combining-the-benefits-of-pectoralis-major-advancement-and-turnover-techniques-for-sternal-wound-reconstruction
#1
Valerie DeGregorio, Shayan Izaddoost
No abstract text is available yet for this article.
September 20, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28938352/the-split-pectoralis-flap-combining-the-benefits-of-pectoralis-major-advancement-and-turnover-techniques-in-one-flap
#2
Francesco Ciancio, Alessandro Innocenti, Aurelio Portincasa, Domenico Parisi
No abstract text is available yet for this article.
September 19, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28938351/-the-split-pectoralis-flap-combining-the-benefits-of-pectoralis-major-advancement-and-turnover-techniques-in-one-flap
#3
Paola Parisi, Federico Lo Torto, Bruno Carlesimo, Diego Ribuffo, Nicolò Scuderi
No abstract text is available yet for this article.
September 19, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28938350/reply-the-split-pectoralis-flap-combining-the-benefits-of-pectoralis-major-advancement-and-turnover-techniques-in-one-flap
#4
Katarzyna Kania, Shayan Izaddoost
No abstract text is available yet for this article.
September 19, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28937840/supraoptimal-activity-of-chlorophyll-dephytylase1-results-in-an-increase-in-tocopherol-level-in-mature-arabidopsis-seeds
#5
Yao-Pin Lin, Yee-Yung Charng
Tocopherols are synthesized in photosynthetic organisms, playing a role in plant stress tolerance. Recent studies showed that the phytol moiety of tocopherols comes from the salvaged phytol chain during chlorophyll degradation. However, the enzyme(s) responsible for chlorophyll dephytylation remains unclear. Recently, we reported the identification and characterization of CHLOROPHYLL DEPHYTYLASE1 (CLD1) of Arabidopsis, suggesting its role in chlorophyll turnover at steady state. In this addendum to the report, we presented and discussed the results related to the function of CLD1 in tocopherol biosynthesis...
September 22, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/28937808/hybridization-associated-with-cycles-of-ecological-succession-in-a-passerine-bird
#6
Renée A Duckworth, Georgy A Semenov
Identifying the diversity of contexts that can lead to hybridization is important for understanding its prevalence and dynamics in natural populations. Despite the potential of ecological succession to dramatically alter species co-occurrence and abundances, it is unknown whether it directly promotes hybridization and, if so, has long-lasting consequences. Here, we summarize 30 years of survey data across 10 populations to show that in western and mountain bluebirds, heterospecific pairing occurs during repeatable and transient colonization events at the early stages of species turnover...
October 2017: American Naturalist
https://www.readbyqxmd.com/read/28937747/photo-and-electrocatalytic-hydrogen-production-using-valence-isomers-of-n2s2-type-nickel-complexes
#7
Satoshi Inoue, Manabu Mitsuhashi, Takeshi Ono, Yin-Nan Yan, Yusuke Kataoka, Makoto Handa, Tatsuya Kawamoto
Three Schiff-base-type nickel(II) complexes (1a-3a) and the corresponding noninnocent-type complexes (1b-3b) were synthesized, and the equilibria between these valence isomers were observed in tetrahydrofuran (THF) at room temperature. The electronic state of the noninnocent-type nickel complex was also confirmed by isolation of the one-electron-reduced species. The catalytic ability for the photogeneration of hydrogen from water was examined about 1a-3a and 1b-3b in the presence of a photosensitizer and a sacrificial electron donor...
September 22, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28937665/a-reductive-aminase-from-aspergillus-oryzae
#8
Godwin A Aleku, Scott P France, Henry Man, Juan Mangas-Sanchez, Sarah L Montgomery, Mahima Sharma, Friedemann Leipold, Shahed Hussain, Gideon Grogan, Nicholas J Turner
Reductive amination is one of the most important methods for the synthesis of chiral amines. Here we report the discovery of an NADP(H)-dependent reductive aminase from Aspergillus oryzae (AspRedAm, Uniprot code Q2TW47) that can catalyse the reductive coupling of a broad set of carbonyl compounds with a variety of primary and secondary amines with up to >98% conversion and with up to >98% enantiomeric excess. In cases where both carbonyl and amine show high reactivity, it is possible to employ a 1:1 ratio of the substrates, forming amine products with up to 94% conversion...
October 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28937247/amino-acid-concentrations-and-protein-metabolism-of-two-types-of-rat-skeletal-muscle-in-postprandial-state-and-after-brief-starvation
#9
M Holeček, S Mičuda
We have investigated amino acid concentrations and protein metabolism in musculus extensor digitorum longus (EDL, fast-twitch, white muscle) and musculus soleus (SOL, slow-twitch, red muscle) of rats sacrificed in the fed state or after one day of starvation. Fractional protein synthesis rates (FRPS) were measured using the flooding dose method (L-[3,4,5-3H]phenylalanine). Activities of two major proteolytic systems in muscle (the ubiquitin-proteasome and lysosomal) were examined by measurement of chymotrypsin like activity of proteasome (CTLA), expression of ubiquitin ligases atrogin-1 and muscle-ring-finger-1 (MuRF-1), and cathepsin B and L activities...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28937054/the-importance-of-bone-biopsy-in-chronic-kidney-disease-mineral-bone-disorders
#10
REVIEW
Periklis Dousdampanis, Kostantina Trigka
Renal osteodystrophy (ROD) is not a uniform bone disease; it is a heterogeneous group of metabolic bone diseases due to chronic kidney disease (CKD). The traditional term of ROD does not accurately include the wide spectrum of "CKD-mineral and bone disorder" (CKD-MBD) and has been restricted to define the several specific histologic disturbances of bone disease associated with CKD. Circulating parathyroid hormone (PTH) and total alkaline phosphatase levels do not always reflect bone turnover in CKD-MBD, whereas bone biopsy provides precise information regarding bone pathology...
September 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28936809/association-between-vitamin-d-and-carboxy-terminal-cross-linked-telopeptide-of-type-i-collagen-in-children-during-growth-hormone-replacement-therapy
#11
Ewelina Witkowska-Sędek, Anna Stelmaszczyk-Emmel, Anna Kucharska, Urszula Demkow, Beata Pyrżak
Growth hormone and insulin-like growth factor-1 (IGF-1) play a crucial role in the regulation of bone turnover. Adequate vitamin D status supports proper bone remodeling, leading to normal longitudinal bone growth and normal peak bone mass. The aim of this study was to evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] and carboxy-terminal cross-linked telopeptide of type I collagen (ICTP) in children and adolescents with growth hormone deficiency at baseline and during recombinant human growth hormone (rhGH) replacement therapy...
September 22, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28936763/sequence-specific-1-h-13-c-and-15-n-resonance-assignments-of-a-cataract-related-variant-g57w-of-human-%C3%AE-s-crystallin
#12
Khandekar Jishan Bari, Shrikant Sharma, Kandala V R Chary
γS-crystallin is a major structural component of the human eye lens, which maintains its stability over the lifetime of an organism with negligible turnover. The G57W mutant of human γS-crystallin (abbreviated hereafter as γS-G57W) is associated with dominant congenital cataracts. In order to provide a structural basis for the ability of γS-G57W causing cataract, we have cloned, overexpressed, isolated and purified the protein. The 2D [(15)N-(1)H]-HSQC spectrum recorded with uniformly (13)C/(15)N-labelled γS-G57W was highly dispersed indicating the protein to adopt an ordered conformation...
September 21, 2017: Biomolecular NMR Assignments
https://www.readbyqxmd.com/read/28936658/analysis-of-peroxisome-biogenesis-in-pollen-by-confocal-microscopy-and-transmission-electron-microscopy
#13
Peng-Fei Jia, Hong-Ju Li, Wei-Cai Yang
Peroxisome is an essential single-membrane bound organelle in most eukaryotic cells and functions in diverse cellular processes. De novo formation, division, and turnover of peroxisomes contribute to its biogenesis, morphology, and population regulation. In plants, peroxisome plays multiple roles, including metabolism, development, and stress response. Defective peroxisome biogenesis and development retard plant growth, adaption, and reproduction. Through tracing the subcellular localization of fluorescent reporter tagged matrix protein of peroxisome, fluorescence microscopy is a reliable and fast way to detect peroxisome biogenesis...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28936606/denosumab-significantly-improves-bone-mineral-density-with-or-without-bisphosphonate-pre-treatment-in-osteoporosis-with-rheumatoid-arthritis-denosumab-improves-bone-mineral-density-in-osteoporosis-with-rheumatoid-arthritis
#14
Yukio Nakamura, Takako Suzuki, Hiroyuki Kato
Bone mineral density (BMD) sometimes cannot be improved by long-term bisphosphonate (BP) therapy in osteoporosis (OP) patients with rheumatoid arthritis (RA). This study showed that BMD significantly increased after denosumab treatment in patients with long-term BP pre-treatment as much as in treatment-naïve patients. Thus, denosumab can be a strong OP treatment option for long-term BP pre-treated RA patients. INTRODUCTION: The aim of this 24-month retrospective study was to evaluate differences in outcomes of denosumab with or without bisphosphonate (BP) pre-treatment in osteoporosis (OP) patients with rheumatoid arthritis (RA)...
September 21, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28936391/evaluation-of-a-multi-year-policy-focused-intervention-to-increase-physical-activity-and-related-behaviors-in-lower-resourced-early-care-and-education-settings-active-early-2-0
#15
Emily J Tomayko, Ronald J Prince, Jill Hoiting, Abbe Braun, Tara L LaRowe, Alexandra K Adams
Physical activity is a critical component of obesity prevention, but few interventions targeting early childhood have been described. The Active Early guide was designed to increase physical activity in early care and education (ECE) settings. The purpose of Active Early 2.0 was to evaluate the effectiveness of Active Early along with provider training, microgrant support, and technical assistance over 2 years (2012-2014) to increase physical activity and related behaviors (e.g., nutrition) in settings serving a high proportion of children from underserved groups in recognition of significant disparities in obesity and challenges meeting physical activity recommendations in low-resource settings...
December 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28935605/pyridoxine-improves-hippocampal-cognitive-function-via-increases-of-serotonin-turnover-and-tyrosine-hydroxylase-and-its-association-with-cb1-cannabinoid-receptor-interacting-protein-and-the-cb1-cannabinoid-receptor-pathway
#16
Hyo Young Jung, Dae Won Kim, Sung Min Nam, Jong Whi Kim, Jin Young Chung, Moo-Ho Won, Je Kyung Seong, Yeo Sung Yoon, Dae Young Yoo, In Koo Hwang
BACKGROUND: In the present study, we investigated the effects of pyridoxine on hippocampal functions and changes in protein profiles based on the proteomic approach. METHODS: Eight-week-old mice received intraperitoneal injections of physiological saline (vehicle) or 350mg/kg pyridoxine twice a day for 21days. RESULTS: Phosphoglycerate mutase 1 was up-regulated, while CB1 cannabinoid receptor-interacting protein 1 (CRIP1) was down-regulated, in the pyridoxine-treated group...
September 18, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28935141/antioxidative-peptide-from-milk-exhibits-antiosteopenic-effects-through-inhibition-of-oxidative-damage-and-bone-resorbing-cytokines-in-ovariectomized-rats
#17
Sanusi Bello Mada, Srinu Reddi, Naveen Kumar, Rohit Kumar, Suman Kapila, Rajeev Kapila, Ritu Trivedi, Anirudha Karvande, Naseer Ahmad
OBJECTIVES: Oxidative stress has been implicated as a crucial pathogenic factor in the development of postmenopausal osteoporosis. Milk-derived antioxidative peptides are gaining much attention toward the development of prodrugs for alleviating several human diseases, including osteoporosis. The aim of the present study was to determine whether antioxidant peptides are good candidates for alleviating postmenopausal osteoporosis. METHODS: In the present study, an ovariectomized (OVX) osteoporotic rat model was used to investigate the protective effects of buffalo milk casein-derived novel peptide VLPVPQK (PEP) against OVX-induced bone loss and the related mechanisms...
November 2017: Nutrition
https://www.readbyqxmd.com/read/28934972/serum-bone-turnover-biomarkers-are-associated-with-the-occurrence-of-peripheral-and-axial-arthritis-in-psoriatic-disease-a-prospective-cross-sectional-comparative-study
#18
Deepak R Jadon, Raj Sengupta, Alison Nightingale, Hui Lu, Juliet Dunphy, Amelia Green, James T Elder, Rajan P Nair, Eleanor Korendowych, Mark A Lindsay, Neil J McHugh
BACKGROUND: A recent systematic review identified four candidate serum-soluble bone-turnover biomarkers (dickkopf-1, Dkk-1; macrophage-colony stimulating factor, M-CSF; matrix metalloproteinase-3, MMP-3; osteoprotegerin, OPG) showing possible association with psoriatic arthritis (PsA). We aimed to: (i) confirm and determine if these four biomarkers are associated with PsA; (ii) differentiate psoriasis cases with and without arthritis; and (iii) differentiate PsA cases with and without axial arthritis...
September 21, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28934392/nceh-1-modulates-cholesterol-metabolism-and-protects-against-%C3%AE-synuclein-toxicity-in-a-c-elegans-model-of-parkinson-s-disease
#19
Siyuan Zhang, Samantha A Glukhova, Kim A Caldwell, Guy A Caldwell
Parkinson's disease (PD) is an aging-associated neurodegenerative disease affecting millions worldwide. Misfolding, oligomerization and accumulation of the human α-synuclein protein is a key pathological hallmark of PD and is associated with the progressive loss of dopaminergic neurons over the course of aging. Lifespan extension via the suppression of IGF-1/insulin-like signaling (IIS) offers a possibility to retard disease onset through induction of metabolic changes that provide neuroprotection. The nceh-1 gene of Caenorhabditis elegans encodes an ortholog of neutral cholesterol ester hydrolase 1 (NCEH-1), an IIS downstream protein that was identified in a screen as a modulator of α-synuclein accumulation in vivo...
October 1, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28934356/reducing-cell-wall-feruloylation-by-expression-of-a-fungal-ferulic-acid-esterase-in-festuca-arundinacea-modifies-plant-growth-leaf-morphology-and-the-turnover-of-cell-wall-arabinoxylans
#20
Marcia M de O Buanafina, Prashanti R Iyer, M Fernanda Buanafina, Erica A Shearer
A feature of cell wall arabinoxylan in grasses is the presence of ferulic acid which upon oxidative coupling by the action of peroxidases forms diferuloyl bridges between formerly separated arabinoxylans. Ferulate cross-linking is suspected of playing various roles in different plant processes. Here we investigate the role of cell wall feruloyaltion in two major processes, that of leaf growth and the turnover of cell wall arabinoxylans on leaf senescence in tall fescue using plants in which the level of cell wall ferulates has been reduced by targeted expression of the Aspergillus niger ferulic acid esterase A (FAEA) to the apoplast or Golgi...
2017: PloS One
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