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Dementia and exercise

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https://www.readbyqxmd.com/read/29164042/different-effects-of-cognitive-and-non-exercise-physical-leisure-activities-on-cognitive-function-by-age-in-elderly-korean-individuals
#1
Mi Sook Jung, Hyunli Kim, Yeji Lee, Mijung Kim, Eunyoung Chung
Objectives: We aimed to examine the effects of various leisure activities on cognitive impairment in young-old (aged 65-74 years) and old-old (aged ≥ 75 years) adults. Methods: In total, 10,279 elderly Korean individuals from the 2014 Korean National Survey on Older Adults' cohort were enrolled in our study. Cognitive impairment was assessed using the standardized score of the Mini-Mental State Examination for Dementia Screening, whereas leisure activities were recorded via self-reporting of the extent and type of leisure activity the subjects involved in over the past year...
October 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/29153754/effects-of-combined-physical-and-cognitive-exercises-on-cognition-and-mobility-in-patients-with-mild-cognitive-impairment-a%C3%A2-randomized-clinical-trial
#2
Hiroyuki Shimada, Hyuma Makizako, Takehiko Doi, Hyuntae Park, Kota Tsutsumimoto, Joe Verghese, Takao Suzuki
IMPORTANCE: Although participation in physical and cognitive activities is encouraged to reduce the risk of dementia, the preventive efficacy of these activities for patients with mild cognitive impairment is unestablished. OBJECTIVE: To compare the cognitive and mobility effects of a 40-week program of combined cognitive and physical activity with those of a health education program. DESIGN: A randomized, parallel, single-blind controlled trial...
November 16, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29149797/findings-from-a-strength-based-moderate-intensity-exercise-interventions-for-individuals-with-dementia-innovative-practice
#3
Nicole Dawson, Hayden Gerhart, Katherine S Judge
Limited evidence exists regarding exercise interventions with individuals with dementia, which is often due to heterogeneity of methodology and outcomes being assessed. This led to the development and evaluation of a moderate-intensity home-based functional exercise program guided by theories from exercise science and the Strength-Based Approach. Data indicated excellent treatment adherence (99.04%) along with high levels of acceptability and feasibility in this sample (age 76.63 years (9.84); Mini Mental State Exam 18...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29149790/impressions-of-using-the-cohen-mansfield-agitation-inventory-as-an-outcome-measure-lessons-learnt-for-future-clinical-researchers-innovative-practice
#4
Lindsey Brett, Victoria Traynor, Shahla Meedya, Paul Stapley
The Cohen-Mansfield Agitation Inventory was a tool originally developed for use in research to measure agitation and subsequently used in clinical settings. It was the primary outcome measure for a randomised controlled trial which evaluated the effects and feasibility of a physiotherapist-led physical exercise intervention on agitation and physical performance of individuals living with dementia in nursing homes. The study produced weak results in regards to the Cohen-Mansfield Agitation Inventory due to small sample size and perceived issues with the use of the Cohen-Mansfield Agitation Inventory...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29149198/experiences-of-older-people-with-dementia-participating-in-a-high-intensity-functional-exercise-program-in-nursing-homes-while-it-s-tough-it-s-useful
#5
Nina Lindelöf, Lillemor Lundin-Olsson, Dawn A Skelton, Berit Lundman, Erik Rosendahl
The objective of the study was to describe the views and experiences of participation in a high-intensity functional exercise (HIFE) program among older people with dementia in nursing homes. The study design was a qualitative interview study with 21 participants (15 women), aged 74-96, and with a Mini-Mental State Examination score of 10-23 at study start. The HIFE-program comprises exercises performed in functional weight-bearing positions and including movements used in everyday tasks. The exercise was individually designed, supervised in small groups in the nursing homes and performed during four months...
2017: PloS One
https://www.readbyqxmd.com/read/29145549/generational-differences-in-the-5-year-incidence-of-age-related-macular-degeneration
#6
Karen J Cruickshanks, David M Nondahl, Lauren J Johnson, Dayna S Dalton, Mary E Fisher, Guan-Hua Huang, Barbara E Klein, Ronald Klein, Carla R Schubert
Importance: Whether a reported decline in the risk of developing age-related macular degeneration (AMD) continued for people born during the Baby Boom years (1946-1964) or later is unknown. These data are important to plan for ocular health care needs in the 21st century. Objectives: To determine whether the 5-year risk for AMD declined by generation and to identify factors that contributed to improvement in risk. Design, Setting, and Participants: Data came from the longitudinal cohort Beaver Dam Eye Study (March 1, 1988, through September 15, 1990, and March 1, 1993, through June 15, 1995) and the Beaver Dam Offspring Study (June 8, 2005, through August 4, 2008, and July 12, 2010, through March 21, 2013)...
November 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29135358/training-area-agencies-on-aging-case-managers-to-improve-physical-function-mood-and-behavior-in-persons-with-dementia-and-caregivers-examples-from-the-rdad-northwest-study
#7
Susan M McCurry, Rebecca G Logsdon, Kenneth C Pike, David M LaFazia, Linda Teri
The Reducing Disability in Alzheimer's Disease (RDAD) program has been shown to be an effective tool for teaching caregivers strategies to improve mood, behavior, and physical function in persons with dementia. This paper describes how RDAD has been translated and implemented for use by Area Agencies on Aging (AAA) case managers across Washington and Oregon. Modifications to the original RDAD program as part of its community translation included decreasing the number of in-person sessions while preserving all educational content; involving caregivers in exercise activities for themselves as well as acting as exercise coaches for care-receivers; and enrolling persons with cognitive impairment due to mixed etiologies...
November 14, 2017: Journal of Gerontological Social Work
https://www.readbyqxmd.com/read/29130020/what-do-we-know-from-clinical-trials-on-exercise-and-alzheimer-s-disease
#8
Yong Shen, Rena Li
Alzheimer's disease (AD) is the most common form of dementia in elderly with major symptoms of a general term for memory loss and other intellectual abilities impairment which are serious enough to interfere with daily life. While there is no treatment can prevent and revise the cognitive function impairment in AD, physical activity becomes a potential beneficial intervention for AD. Multiple evidences suggested that exercise in general plays beneficial roles in improving brain function. Most common mechanisms of exercise-induced enhancement of brain function are including alteration of neurogenesis, neuron plasticity, neuronal signaling and receptors, as well as neuronal networks...
December 2016: Journal of Sport and Health Science
https://www.readbyqxmd.com/read/29126372/exercise-improves-recognition-memory-and-synaptic-plasticity-in-the-prefrontal-cortex-for-rats-modelling-vascular-dementia
#9
Juntao Dong, Jingpu Zhao, Yangyang Lin, Huiying Liang, Xiaokuo He, Xiuyuan Zheng, Minghong Sui, Zhiqiang Zhuang, Tiebin Yan
OBJECTIVES: Functional electrical stimulation (FES) may induce involuntary exercise and make beneficial effects on vascular dementia (VD) by strengthening the BDNF-pCREB-mediated pathway and hippocampal plasticity. Whether FES improves recognition memory and synaptic plasticity in the prefrontal cortex (PFC) was investigated by establishing a VD model. METHODS: The VD rats were administered with two weeks of voluntary exercise, forced exercise, or involuntary exercise induced with FES...
November 10, 2017: Neurological Research
https://www.readbyqxmd.com/read/29124115/study-protocol-of-the-intense-physical-activity-and-cognition-study-the-effect-of-high-intensity-exercise-training-on-cognitive-function-in-older-adults
#10
Belinda M Brown, Stephanie R Rainey-Smith, Natalie Castalanelli, Nicole Gordon, Shaun Markovic, Hamid R Sohrabi, Michael Weinborn, Simon M Laws, James Doecke, Kaikai Shen, Ralph N Martins, Jeremiah J Peiffer
Introduction: Inconsistent results from previous studies of exercise and cognitive function suggest that rigorously designed randomized controlled trials are urgently needed. Here, we describe the design of the Intense Physical Activity and Cognition (IPAC) study, which will assess the impact of a 6-month high-intensity exercise intervention on cognitive function and biomarkers of dementia risk, compared with a 6-month moderate-intensity exercise intervention and control group (no study-related exercise)...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29119954/-the-role-of-dosed-walking-in-the-combination-with-elements-of-cognitive-training-in-the-comprehensive-treatment-of-the-patients-presenting-with-alzheimer-s-disease
#11
N A Zimushkina, P V Kosareva, V G Cherkasova
AIM: The objective of the present study was to evaluate the effectiveness of dosed physical exercises for the combined treatment of the patients presenting with mild to moderate dementia associated with Alzheimer's disease (AD). MATERIAL AND METHODS: The comprehensive examination involved 41 patients (32 women and 9 men) with the confirmed diagnosis of 'probable' AD with stages 1 and 2 of dementia and 17 healthy volunteers comprising the group of comparison. In all the patients, the neurological examination was supplemented by neuropsychological testing...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29108442/the-effects-of-exercise-on-memory-function-among-young-to-middle-aged-adults-systematic-review-and-recommendations-for-future-research
#12
Paul D Loprinzi, Emily Frith, Meghan K Edwards, Eveleen Sng, Nicole Ashpole
OBJECTIVE: To systematically summarize the experimental effects of exercise on cognitive-related memory function among young to middle-aged adults, which has yet to be done in the literature. DATA SOURCE: PubMed. STUDY INCLUSION AND EXCLUSION CRITERIA: Studies were included if they were published in the English language, indexed in PubMed, employed an experimental study design (eg, traditional parallel group randomized controlled trial: either acute intervention or chronic/training intervention study), and conducted among human adults...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29096630/trajectories-of-physical-function-prior-to-death-and-brain-neuropathology-in-a-community-based-cohort-the-act-study
#13
Andrea Z LaCroix, Rebecca A Hubbard, Shelly L Gray, Melissa L Anderson, Paul K Crane, Joshua A Sonnen, Oleg Zaslavsky, Eric B Larson
BACKGROUND: Mechanisms linking cognitive and physical functioning in older adults are unclear. We sought to determine whether brain pathological changes relate to the level or rate of physical performance decline. METHODS: This study analyzed data from 305 participants in the autopsy subcohort of the prospective Adult Changes in Thought (ACT) study. Participants were aged 65+ and free of dementia at enrollment. Physical performance was measured at baseline and every two years using the Short Physical Performance Battery (SPPB)...
November 2, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29070481/examining-internet-and-ehealth-practices-and-preferences-survey-study-of-australian-older-adults-with-subjective-memory-complaints-mild-cognitive-impairment-or-dementia
#14
Haley M LaMonica, Amelia English, Ian B Hickie, Jerome Ip, Catriona Ireland, Stacey West, Tim Shaw, Loren Mowszowski, Nick Glozier, Shantel Duffy, Alice A Gibson, Sharon L Naismith
BACKGROUND: Interest in electronic health (eHealth) technologies to screen for and treat a variety of medical and mental health problems is growing exponentially. However, no studies to date have investigated the feasibility of using such e-tools for older adults with mild cognitive impairment (MCI) or dementia. OBJECTIVE: The objective of this study was to describe patterns of Internet use, as well as interest in and preferences for eHealth technologies among older adults with varying degrees of cognitive impairment...
October 25, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29070027/absolute-and-relative-reliability-of-acute-effects-of-aerobic-exercise-on-executive-function-in-seniors
#15
Lars Donath, Sebastian Ludyga, Daniel Hammes, Anja Rossmeissl, Nadin Andergassen, Lukas Zahner, Oliver Faude
BACKGROUND: Aging is accompanied by a decline of executive function. Aerobic exercise training induces moderate improvements of cognitive domains (i.e., attention, processing, executive function, memory) in seniors. Most conclusive data are obtained from studies with dementia or cognitive impairment. Confident detection of exercise training effects requires adequate between-day reliability and low day-to-day variability obtained from acute studies, respectively. These absolute and relative reliability measures have not yet been examined for a single aerobic training session in seniors...
October 25, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29067335/sedentary-behavior-as-a-risk-factor-for-cognitive-decline-a-focus-on-the-influence-of-glycemic-control-in-brain-health
#16
REVIEW
Michael J Wheeler, Paddy C Dempsey, Megan S Grace, Kathryn A Ellis, Paul A Gardiner, Daniel J Green, David W Dunstan
Cognitive decline leading to dementia represents a global health burden. In the absence of targeted pharmacotherapy, lifestyle approaches remain the best option for slowing the onset of dementia. However, older adults spend very little time doing moderate to vigorous exercise and spend a majority of time in sedentary behavior. Sedentary behavior has been linked to poor glycemic control and increased risk of all-cause mortality. Here, we explore a potential link between sedentary behavior and brain health. We highlight the role of glycemic control in maintaining brain function and suggest that reducing and replacing sedentary behavior with intermittent light-intensity physical activity may protect against cognitive decline by reducing glycemic variability...
September 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29067325/design-of-the-excersion-vci-study-the-effect-of-aerobic-exercise-on-cerebral-perfusion-in-patients-with-vascular-cognitive-impairment
#17
Anna E Leeuwis, Astrid M Hooghiemstra, Raquel Amier, Doeschka A Ferro, Leonie Franken, Robin Nijveldt, Joost P A Kuijer, Anne-Sophie G T Bronzwaer, Johannes J van Lieshout, Marc B Rietberg, Janne M Veerbeek, Rosalie J Huijsmans, Frank J G Backx, Charlotte E Teunissen, Esther E Bron, Frederik Barkhof, Niels D Prins, Rahil Shahzad, Wiro J Niessen, Albert de Roos, Matthias J P van Osch, Albert C van Rossum, Geert J Biessels, Wiesje M van der Flier
There is evidence for a beneficial effect of aerobic exercise on cognition, but underlying mechanisms are unclear. In this study, we test the hypothesis that aerobic exercise increases cerebral blood flow (CBF) in patients with vascular cognitive impairment (VCI). This study is a multicenter single-blind randomized controlled trial among 80 patients with VCI. Most important inclusion criteria are a diagnosis of VCI with Mini-Mental State Examination ≥22 and Clinical Dementia Rating ≤0.5. Participants are randomized into an aerobic exercise group or a control group...
June 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29067323/intermittent-hypoxic-hyperoxic-training-on-cognitive-performance-in-geriatric-patients
#18
Urike Bayer, Rudolf Likar, Georg Pinter, Haro Stettner, Susanne Demschar, Brigitte Trummer, Stefan Neuwersch, Oleg Glazachev, Martin Burtscher
INTRODUCTION: Intermittent hypoxic-hyperoxic training (IHHT) may complement a multimodal training intervention (MTI) for improving cognitive function and exercise tolerance in geriatric patients. METHODS: Thirty-four patients (64-92 years) participated in this randomized controlled trial. Before and after the 5- to 7-week intervention period (MTI + IHHT vs. MTI + ambient air), cognitive function was assessed by the Dementia-Detection Test (DemTect) and the Sunderland Clock-Drawing Test (CDT), and functional exercise capacity by the total distance of the 6-Minute Walk Test (6MWT)...
January 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29066293/the-mental-activity-and-exercise-max-trial-effects-on-physical-function-and-quality-of-life-among-older-adults-with-cognitive-complaints
#19
Laura E Middleton, Maria I Ventura, Wendy Santos-Modesitt, Gina Poelke, Kristine Yaffe, Deborah E Barnes
BACKGROUND: Older adults with cognitive complaints are vulnerable to dementia, physical impairments, and poor quality of life. Exercise and mental activity may improve physical function and health-related quality of life (HRQOL) but combinations have not been investigated systematically. The Mental Activity and eXercise (MAX) trial found that mental activity plus exercise over 12weeks improved cognitive function (primary outcome) in sedentary older adults with cognitive complaints. OBJECTIVE: To investigate the effects of combinations of two mental activity and exercise programs on physical function and HRQOL (secondary outcomes)...
October 21, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29062537/tea-talk-and-technology-patient-and-public-involvement-to-improve-connected-health-wearables-research-in-dementia
#20
Lamiece Hassan, Caroline Swarbrick, Caroline Sanders, Angela Parker, Matt Machin, Mary P Tully, John Ainsworth
PLAIN ENGLISH SUMMARY: There are a growing number of mobile phones, watches and electronic devices which can be worn on the body to track aspects of health and well-being, such as daily steps, sleep and exercise. Dementia researchers think that these devices could potentially be used as part of future research projects, for example to help spot changes in daily activity that may signal the early symptoms of dementia. We asked a range of older people, including people living with dementia and their carers, to participate in interactive discussions about how future participants might find using these devices as part of research projects...
2017: Res Involv Engagem
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