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Dementia and exercise

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https://www.readbyqxmd.com/read/29769247/dementia-and-physical-activity-dapa-trial-of-moderate-to-high-intensity-exercise-training-for-people-with-dementia-randomised-controlled-trial
#1
Sarah E Lamb, Bart Sheehan, Nicky Atherton, Vivien Nichols, Helen Collins, Dipesh Mistry, Sukhdeep Dosanjh, Anne Marie Slowther, Iftekhar Khan, Stavros Petrou, Ranjit Lall
OBJECTIVE: To estimate the effect of a moderate to high intensity aerobic and strength exercise training programme on cognitive impairment and other outcomes in people with mild to moderate dementia. DESIGN: Multicentre, pragmatic, investigator masked, randomised controlled trial. SETTING: National Health Service primary care, community and memory services, dementia research registers, and voluntary sector providers in 15 English regions. PARTICIPANTS: 494 people with dementia: 329 were assigned to an aerobic and strength exercise programme and 165 were assigned to usual care...
May 16, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29764877/efficacy-of-practising-tai-chi-for-older-people-with-mild-dementia-protocol-for-a-randomised-controlled-study
#2
Jihui Lyu, Wenjie Li, Xiangjiang Rong, Lian Wei, Nayan Huang, Mei Champ, Qian Xiong, Xueli Chen, Mo Li, Fangling Li
INTRODUCTION: Many studies suggest that Tai Chi exercise is a safe and appropriate mind-body exercise for older people and effectively slows down age-related cognitive decline. A set of bespoke Tai Chi exercise named 'Cognition Protecting Tai Chi' (CPT) has been created for older people with cognitive impairments by the research team of geriatricians, neurologists, rehabilitation specialists, experts of sports medicine and experienced practitioners of traditional Chinese medicine. This trial is designed to evaluate its effects on cognitive function, behaviour/moods, risk of falls and activities of daily living of the participants with mild dementia...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29761589/prevalence-and-effect-factors-of-dementia-among-the-community-elderly-in-chongqing-china
#3
Jing Deng, Cheng Cao, Yi Jiang, Bin Peng, Tingting Wang, Ke Yan, Jingxi Lian, Zengzi Wang
BACKGROUND: China is an ageing society, with around 150 million people aged 60 years or older. The prevalence of dementia will increase by more than 100% in the coming 20 years. This study aimed to investigate the prevalence and effects of dementia among the community elderly in Chongqing, China. METHODS: Cluster sampling was adopted. A sample of elderly individuals aged 60 years and older was extracted as research subjects from three counties within Chongqing, China...
May 14, 2018: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/29750023/the-effects-of-movement-stimulation-on-activities-of-daily-living-performance-and-quality-of-life-in-nursing-home-residents-with-dementia-a-randomized-controlled-trial
#4
Marinda Henskens, Ilse M Nauta, Katja T Drost, Erik Ja Scherder
Background: Nursing home (NH) residents with dementia experience a reduced quality of life (QoL), in part, due to a dependence in performing activities of daily living (ADL). Stimulating movement is associated with improvements in ADL performance. Therefore, movement stimulating interventions, such as ADL training and exercise, focus on optimizing ADL performance to improve QoL. This study aimed to evaluate the effect of three movement stimulating interventions on QoL and ADL performance in NH residents with dementia...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29740562/effects-of-exercise-training-on-stroke-risk-factors-homocysteine-concentration-and-cognitive-function-according-the-apoe-genotype-in-stroke-patients
#5
Jun-Hee Lee, Sang-Min Hong, Yun-A Shin
The apolipoprotein E ( APOE ) gene has been suggested to be associated with stroke and dementia. However, the effects of exercise training on dementia according to the APOE genotype are not consistent to those reported by previous studies. Therefore, we examined the effects of exercise training on stroke risk factors including blood pressure, lipid profiles, homocysteine (Hcy) concentrations, and cognitive function according to the APOE genotype in stroke patients. We examined the stroke risk factors, Hcy, and cognitive function in 28 ischemic stroke patients before and after 6 months of exercise training...
April 2018: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29740553/development-and-validation-of-exercise-rehabilitation-program-for-cognitive-function-and-activity-of-daily-living-improvement-in-mild-dementia-elderly
#6
Mi-Ri Choi, Ji-Youn Kim, Eun-Surk Yi
We investigated the effect of exercise rehabilitation based on fine motor movement for the elderly with mild dementia. Using electroencephalogram (EEG), the change of brain wave of them based on fine motor movement and comparing the improvement level of cognitive ability and performance capability in daily living activity was recorded. The subjects were the elderly with mild dementia living in a sanatorium in Incheon city. Mini-Mental Status Examination, activity of daily living (ADL), and the influence on depression were examined...
April 2018: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29738405/effect-of-exercise-on-cognition-conditioning-muscle-endurance-and-balance-in-older-adults-with-mild-cognitive-impairment-a-randomized-controlled-trial
#7
Chandra da Silveira Langoni, Thais de Lima Resende, Andressa Bombardi Barcellos, Betina Cecchele, Mateus Soares Knob, Tatiane do Nascimento Silva, Juliana Nunes da Rosa, Tamiris de Souza Diogo, Irenio Gomes da Silva Filho, Carla Helena Augustin Schwanke
BACKGROUND AND PURPOSE: Mild cognitive impairment (MCI) may be a precursor to dementia; however, its progression may be prevented or slowed with exercise. This study aimed at determining the effects of group aerobic and strength training on cognition, conditioning, muscle endurance, and balance in underprivileged community-dwelling older adults with MCI. METHODS: This was a single-blind, randomized, and matched-pair controlled (gender, age, body mass index, and Addenbrooke's Cognitive Examination-Revised for MCI diagnosis) clinical trial...
May 4, 2018: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29736953/cognitive-and-physical-factors-affecting-daily-function-in-alzheimer-s-disease-a-cross-sectional-analysis
#8
Fang Yu, Yan Chen, Michelle A Mathiason, Qiaoqin Wan, Feng V Lin
Understanding the factors affecting activities of daily living (ADL) is important in Alzheimer's disease (AD), because decline in ADL contributes to many poor health outcomes. Existing studies often investigate the factors in isolation without a theoretical framework. The purpose of the present study was to provide preliminary results on how cognition, physical performance, and behavioral and psychological symptoms of dementia mediate the relationship of aerobic fitness and ADL in AD. A cross-sectional analysis was used (n = 28: average age 78 [8] years, education 16 (3) years, Mini-Mental State Examination scores 20 [4])...
May 7, 2018: Nursing & Health Sciences
https://www.readbyqxmd.com/read/29729254/physical-exercise-reserved-amyloid-beta-induced-brain-dysfunctions-by-regulating-hippocampal-neurogenesis-and-inflammatory-response-via-mapk-signaling
#9
Li-Na Sun, Jin-Shun Qi, Rong Gao
Alzheimer's disease (AD) is one of the leading causes of dementia that induced by aggregation of amyloid-beta (Aβ) in brain tissue. With high structural and functional plasticity, hippocampus plays fundamental roles in cognitive regulation. Moreover, impaired hippocampal functions present during early onset of AD. Hence, targeting on improving hippocampal plasticity would be recognized as the effective strategy in AD therapy. Physical exercise is widely encouraged healthy life style. However, whether exercise could reserve the neural dysfunctions in AD model and the possible neurobiological mechanism still need for better understanding...
May 2, 2018: Brain Research
https://www.readbyqxmd.com/read/29723176/the-dunedin-dementia-risk-awareness-project-a-convenience-sample-of-general-practitioners
#10
Yoram Barak, Charlene Rapsey, Dana Fridman, Kate Scott
AIMS: Recent recommendations of US and UK governmental and academic agencies suggest that up to 35% of dementia cases are preventable. We aimed to appraise general practitioners' (GPs) awareness of risk and protective factors associated with dementia and their intentions to act within the context of the Health Beliefs Model. METHODS: We canvassed degree of dementia awareness, using the modified Lifestyle for Brain Health (LIBRA) scale among a convenience sample of local GPs...
May 4, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29718064/cardiorespiratory-fitness-and-risk-of-dementia-a-prospective-population-based-cohort-study
#11
S Kurl, J A Laukkanen, E Lonnroos, A M Remes, H Soininen
Dementia is considered to be one of the major public health problems in light of the ageing population. Little is known about directly measured cardiorespiratory fitness as measured by maximal oxygen uptake and the risk of dementia. Our aim was to examine the relationship of cardiorespiratory fitness, as indicated by maximal oxygen uptake, with subsequent incidence of dementia. This was a population-based cohort study with an average follow-up of 22 (range 0.22-29.8) years from eastern Finland. About 2,031 men with a mean age of 52...
April 28, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29713339/exercise-intervention-associated-with-cognitive-improvement-in-alzheimer-s-disease
#12
REVIEW
Meng Ying Cui, Yang Lin, Ji Yao Sheng, Xuewen Zhang, Ran Ji Cui
Alzheimer's disease (AD) is a progressive neurodegenerative disease with the syndrome of cognitive and functional decline. Pharmacotherapy has always been in a dominant position for the treatment of AD. However, in most cases, drug therapy is accompanied with clinical delays when older adults have suffered from cognitive decline in episodic memory, working memory, and executive function. On the other hand, accumulating evidence suggests that exercise intervention may ameliorate the progression of cognitive impairment in aging ones while the standard strategy is lacking based on different levels of cognitive decline especially in mild cognitive impairment (MCI) and AD...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29706882/cognitive-function-and-brain-atrophy-predict-non-pharmacological-efficacy-in-dementia-the-mihama-kiho-scan-project2
#13
Ken-Ichi Tabei, Masayuki Satoh, Jun-Ichi Ogawa, Tomoko Tokita, Noriko Nakaguchi, Koji Nakao, Hirotaka Kida, Hidekazu Tomimoto
We aimed to determine whether neuropsychological deficits and brain atrophy could predict the efficacy of non-pharmacological interventions. Forty-six participants with mild-to-moderate dementia were monitored for 6 months; 25 underwent an intervention involving physical exercise with music, and 21 performed cognitive stimulation tasks. Participants were categorized into improvement (IMP) and no-IMP subgroups. In the exercise-with-music group, the no-IMP subgroup performed worse than the IMP subgroup on the Rivermead Behavioural Memory Test at baseline...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29705888/a-physical-exercise-program-using-music-supported-video-based-training-in-older-adults-in-nursing-homes-suffering-from-dementia-a-feasibility-study
#14
Joke Spildooren, Ite Speetjens, Johan Abrahams, Peter Feys, Annick Timmermans
BACKGROUND: Motivation towards an exercise program is higher in a small group setting in comparison to individual therapy. Due to attentional problems, group exercises are difficult for people with Alzheimer disease (AD). This study evaluates the feasibility of a music-supported video-based group exercise program in older adults suffering from AD. METHODS: Five participants with moderate AD were recruited from a nursing home. A progressive physical exercise program using a video-based training with musical accompaniment was performed and digitally recorded to investigate the adherence and performed accuracy of the exercises...
April 28, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29697780/new-horizons-in-fall-prevention
#15
Stephen R Lord, Jacqueline C T Close
Falls pose a major threat to the well-being and quality of life of older people. Falls can result in fractures and other injuries, disability and fear and can trigger a decline in physical function and loss of autonomy. This article synthesises recent published findings on fall risk and mobility assessments and fall prevention interventions and considers how this field of research may evolve in the future. Fall risk topics include the utility of remote monitoring using wearable sensors and recent work investigating brain activation and gait adaptability...
April 25, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29694602/is-the-telomere-length-associated-with-neurocognitive-disabilities-in-hiv-1-infected-subjects
#16
Marilia Ladeira de Araújo, Wellington Duarte, Augusto César Penalva de Oliveira, Maria Rita Polo Gascón, Luiz Augusto Marcondes Fonseca, Raquel de Melo Alves Paiva, Bárbara Santana, Rodrigo Tocantins Calado, Jorge Casseb
OBJECTIVE: We evaluated the association between cognitive deficits and leukocyte telomere length (LTL) in HIV-1-infected individuals. DESIGN: 73 HIV-1-infected patients undergoing neuropsychological evaluation and 91 healthy controls were included in this study. Fifteen HIV-1 positive patients did not have cognitive disorders whereas 26 had asymptomatic neurocognitive disorder (ANI), 13 presented mild to moderate neurocognitive disorder (MND), and 10 had HIV-associated dementia (HAD)...
2018: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29689716/effects-of-exergaming-in-people-with-dementia-results-of-a-systematic-literature-review
#17
Joeke van Santen, Rose-Marie Dröes, Marije Holstege, Olivier Blanson Henkemans, Annelies van Rijn, Ralph de Vries, Annemieke van Straten, Franka Meiland
BACKGROUND: Physical exercise benefits functioning, health, and well-being. However, people living with dementia in particular hardly engage in exercise. Exergaming (exercise and gaming) is an innovative, fun, and relatively safe way of exercising in a virtual reality or gaming environment. It may help people living with dementia overcome barriers they can experience regarding regular exercise activities. OBJECTIVE: This systematic literature review aims to provide an overview of the cost-effectiveness of exergaming and its effects on physical, cognitive, emotional, and social functioning, as well as the quality of life in people living with dementia...
April 17, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29688637/-rehabilitation-of-mobility-and-motor-function-in-nursing-home-residents-with-dementia
#18
Efraim Aizen, Enna Lubosky, Saleh Sobeh, Rasha Ibrahim, Dina Pressburger, Roni Oliven
BACKGROUND: Few clinical trials have evaluated exercise programs developed specifically for patients with dementia in nursing home settings. OBJECTIVES: To determine if a training program tailored for demented patients, can be implemented in a nursing home setting in order to improve motor performances in patients with dementia who suffered functional decline. METHODS: The present intervention was conducted in wards of patients suffering from dementia in three nursing homes...
April 2018: Harefuah
https://www.readbyqxmd.com/read/29669488/physical-activity-and-exercise-therapy-benefits-more-than-just-symptoms-and-impairments-in-people-with-hip-and-knee-osteoarthritis
#19
Søren T Skou, Bente Klarlund Pedersen, J Haxby Abbott, Brooke Patterson, Christian Barton
Synopsis Hip and knee osteoarthritis (OA) are among the leading causes of global disability, highlighting the need for early, targeted, and effective treatments. The benefits on symptoms and impairments of exercise therapy in people with hip and knee OA are substantial and supported by high-quality evidence, underlining that it should be part of first line treatment offered to all people with hip and knee OA in clinical practice. Furthermore, unlike other treatments for OA such as analgesia and surgery, exercise therapy is not associated with risk of serious harm...
April 18, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29667567/cardiovascular-health-and-cognitive-function-among-mexican-older-adults-cross-sectional-results-from-the-who-study-on-global-ageing-and-adult-health
#20
Jaime Perales, Ladson Hinton, Jeffrey Burns, Eric D Vidoni
ABSTRACTObjectives:To assess the association between cardiovascular health and cognitive function among Mexican older adults. DESIGN: Nationally representative cross-sectional survey. SETTING: Households in Mexico. PARTICIPANTS: Individuals aged 50 years and older (n = 1,492) from the Mexico-SAGE project Wave 1. MEASUREMENTS: A continuous and a categorical index of cardiovascular health was calculated based on exercise, smoking, body mass index, and blood pressure ranging from 0 to 4...
April 18, 2018: International Psychogeriatrics
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