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Dementia and exercise

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https://www.readbyqxmd.com/read/28210939/deep-phenotyping-of-systemic-arterial-hemodynamics-in-hfpef-part-1-physiologic-and-technical-considerations
#1
REVIEW
Julio A Chirinos
A better understanding of the pathophysiology of heart failure with a preserved left ventricular ejection fraction (HFpEF) is important. Detailed phenotyping of pulsatile hemodynamics has provided important insights into the pathophysiology of left ventricular remodeling and fibrosis, diastolic dysfunction, microvascular disease, and impaired oxygen delivery to peripheral skeletal muscle, all of which contribute to exercise intolerance, the cardinal feature of HFpEF. Furthermore, arterial pulsatile hemodynamic mechanisms likely contribute to the frequent presence of comorbidities, such as renal failure and dementia, in this population...
February 16, 2017: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/28187125/aerobic-exercise-for-alzheimer-s-disease-a-randomized-controlled-pilot-trial
#2
Jill K Morris, Eric D Vidoni, David K Johnson, Angela Van Sciver, Jonathan D Mahnken, Robyn A Honea, Heather M Wilkins, William M Brooks, Sandra A Billinger, Russell H Swerdlow, Jeffrey M Burns
BACKGROUND: There is increasing interest in the role of physical exercise as a therapeutic strategy for individuals with Alzheimer's disease (AD). We assessed the effect of 26 weeks (6 months) of a supervised aerobic exercise program on memory, executive function, functional ability and depression in early AD. METHODS AND FINDINGS: This study was a 26-week randomized controlled trial comparing the effects of 150 minutes per week of aerobic exercise vs. non-aerobic stretching and toning control intervention in individuals with early AD...
2017: PloS One
https://www.readbyqxmd.com/read/28177149/relational-citizenship-supporting-embodied-selfhood-and-relationality-in-dementia-care
#3
Pia Kontos, Karen-Lee Miller, Alexis P Kontos
We draw on findings from a mixed-method study of specialised red-nosed elder-clowns in a long-term care facility to advance a model of 'relational citizenship' for individuals with dementia. Relational citizenship foregrounds the reciprocal nature of engagement and the centrality of capacities, senses, and experiences of bodies to the exercise of human agency and interconnectedness. We critically examine elder-clown strategies and techniques to illustrate how relational citizenship can be supported and undermined at the micro level of direct care through a focus on embodied expressions of creativity and sexuality...
February 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28149509/music-therapy-is-a-potential-intervention-for-cognition-of-alzheimer-s-disease-a-mini-review
#4
REVIEW
Rong Fang, Shengxuan Ye, Jiangtao Huangfu, David P Calimag
Alzheimer's Disease (AD) is a global health issue given the increasing prevalence rate and the limitations of drug effects. As a consequent, non-pharmacological interventions are of importance. Music therapy (MT) is a non-pharmacological way with a long history of use and a fine usability for dementia patients. In this review, we will summarize different techniques, diverse clinical trials, and the mechanisms of MT as it is helpful to the cognition in AD, providing reference for future research. Many articles have demonstrated that MT can reduce cognitive decline especially in autobiographical and episodic memories, psychomotor speed, executive function domains, and global cognition...
2017: Translational Neurodegeneration
https://www.readbyqxmd.com/read/28133983/involving-individuals-with-dementia-as-co-researchers-in-analysis-of-findings-from-a-qualitative-study
#5
Mabel Stevenson, Brian J Taylor
Patient and public involvement is widely accepted as good practice in dementia research contributing substantial benefits to research quality. Reports detailing involvement of individuals with dementia as co-researchers, more specifically in analysis of findings are lacking. This paper reports an exercise involving individuals with dementia as co-researchers in a qualitative analysis. Data was from anonymised extracts of interviews with people with dementia who had participated in a multistage study on risk communication in dementia care, relating to concepts and communication of risk...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28120631/the-effects-of-a-multicomponent-dyadic-intervention-with-physical-exercise-on-the-cognitive-functioning-of-people-with-dementia-a-randomized-controlled-trial
#6
Anna-Eva Prick, Jacomine de Lange, Erik Scherder, Jos Twisk, Anne Margriet Pot
OBJECTIVE: To evaluate the effects of a multicomponent dyadic intervention on the cognitive functioning of people with dementia living at home in a Randomized Controlled Trial. METHODS: People with dementia and their family caregivers (n=111) were randomly assigned to 8 home based sessions including physical exercise and support or a minimal intervention consisting of monthly written information bulletins and monthly phone calls. Memory, Executive Functioning (EF) and attention were assessed at baseline, and after three (post-measurement) and six months (follow-up)...
January 25, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28119873/treadmill-exercise-ameliorates-symptoms-of-alzheimer-disease-through-suppressing-microglial-activation-induced-apoptosis-in-rats
#7
Seung-Soo Baek, Sang-Hoon Kim
Alzheimer disease (AD) is a most common form of dementia and eventually causes impairments of learning ability and memory function. In the present study, we investigated the effects of treadmill exercise on the symptoms of AD focusing on the microglial activation-induced apoptosis. AD was made by bilateral intracerebroventricular injection of streptozotocin. The rats in the exercise groups were made to run on a treadmill once a day for 30 min during 4 weeks. The distance and latency in the Morris water maze task and the latency in the step-down avoidance task were increased in the AD rats, in contrast, treadmill exercise shortened these parameters...
December 2016: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28112351/nonpharmacological-strategies-for-patients-with-early-stage-dementia-or-mild-cognitive-impairment-a-10-year-update
#8
Joel G Anderson, Ruth Palan Lopez, Karen M Rose, Janet K Specht
As the incidence and prevalence of early-stage Alzheimer's disease and mild cognitive impairment increases worldwide, gerontological researchers continue to examine the efficacy and effectiveness of strategies to help patients and caregivers live with the disease. Although pharmacological treatments remain the focus of much of the research, nonpharmacological strategies and approaches to care continue to gain ground as effective means of improving the health-related quality of life for this patient population...
January 1, 2017: Research in Gerontological Nursing
https://www.readbyqxmd.com/read/28108255/regular-exercise-promotes-memory-function-and-enhances-hippocampal-neuroplasticity-in-experimental-autoimmune-encephalomyelitis-mice
#9
Tae-Woon Kim, Yun-Hee Sung
Multiple sclerosis (MS) is a progressive condition affecting the central nervous system (CNS), and is characterized by the development of demyelinated lesions and plaques in the brain and spinal cord. Exercise is beneficial against dementia in elderly patients, so we investigated the effects of exercise on memory in relation to hippocampal demyelination and neuroplasticity in a mouse model of MS (experimental autoimmune encephalomyelitis [EAE]). Mice were randomly divided into three groups: Sham, EAE, and EAE and exercise (EAE+EX)...
January 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/28101699/humanity-at-the-edge-the-moral-laboratory-of-feeding-precarious-lives
#10
Mette N Svendsen, Iben M Gjødsbøl, Mie S Dam, Laura E Navne
At the heart of anthropology and the social sciences lies a notion of human existence according to which humans and animals share the basic need for food, but only humans have the capacity for morality. Based on fieldwork in a pig laboratory, a neonatal intensive care unit (NICU), and a dementia nursing home, we follow practices of feeding precarious lives lacking most markers of human personhood, including the exercise of moral judgment. Despite the absence of such markers, laboratory researchers and caregivers in these three sites do not abstain from engaging in questions about the moral status of the piglets, infants, and people with dementia in their care...
January 18, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/28078981/resilience-to-alzheimer-s-disease-the-role-of-physical-activity
#11
Anna Pedrinolla, Federico Schena, Massimo Venturelli
BACKGROUND: Although Alzheimer's disease (AD) is a neurodegenerative pathology characterized by accumulation of β-amyloid plaques and neurofibrillary tangles at cerebral level, recent studies highlighted that AD might be the result of many altered physiological processes occurring at whole-organism level. The ability to adapt to stressors by "bending" but not "breaking" can be considered as "resilience". Individuals incline to withstand such pathophysiological challenges, can be considered more resilient than those that do not...
11, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28074678/prevention-of-alzheimer-s-disease-cerebrovascular-disease-and-dementia-in-women-the-case-for-menopause-hormone-therapy
#12
Dennis A Davey
Alzheimer's disease, cerebrovascular disease and aging-related cognitive impairment and dementia (ARCID) increase in prevalence in women with advancing age. The development of Alzheimer's disease, cerebrovascular disease and ARCID may be postponed or prevented by protective measures including the active treatment of vascular risk factors and continuing exercise and healthy lifestyle from early- and mid-life onward. Bilateral oophorectomy before the natural menopause is associated with an increased incidence of ARCID and the increased risk is significantly reduced by estrogen therapy...
February 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28067736/alzheimer-s-disease-and-exercise-a-literature-review
#13
Shane P Cass
Alzheimer's disease (AD) is a progressive neurodegenerative disease that impairs memory and cognitive judgment. It is the leading cause of dementia in late adult life and is associated with a significant social burden and increased morbidity and mortality in the elderly. Because of mixed effectiveness of medications, exercise has been considered as a treatment for pre-clinical AD, late stage AD, and as a prevention strategy. Exercise appears to improve brain blood flow, increase hippocampal volume, and improve neurogenesis...
January 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28058207/memory-loss-five-new-things
#14
Ferenc Deak, Nidhi Kapoor, Calin Prodan, Linda A Hershey
PURPOSE OF REVIEW: Memory loss can be due to a wide variety of causes. We provide new information about the biology of common genetic and acquired causes of memory loss in older adults. RECENT FINDINGS: New data are available about the genetics of Alzheimer disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia. Amyloid PET, FDG-PET, and MRI have improved our understanding of how mild cognitive impairment evolves to AD. Several studies have shown links between concussion and chronic traumatic encephalopathy...
December 2016: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/28057424/sundown-syndrome-sleep-quality-and-walking-among-community-dwelling-people-with-alzheimer-disease
#15
Yen-Hua Shih, Ming-Chyi Pai, Ying-Che Huang, Jing-Jy Wang
PURPOSES: Sundown syndrome and sleep disturbances cause people with Alzheimer disease (PAD) and caregivers suffering. Studies have indicated that physical exercise could have a positive impact on sundown syndrome, yet no research has ever explored the relationship between walking and sundown syndrome. The aims of this study were to examine the relationship between sundown syndrome and sleep quality, and determine whether the severity of dementia, sleep quality, and weekly duration of walking influenced sundown syndrome, and to assess differences in sundown syndrome and sleep quality in relation to the accompanying walker and weekly duration of walking among people with Alzheimer disease living in the community...
January 2, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28042920/being-a-close-family-member-of-a-person-with-dementia-living-in-a-nursing-home
#16
Berit Seiger Cronfalk, Britt-Marie Ternestedt, Astrid Norberg
AIM AND OBJECTIVE: To illuminate how family members of persons with dementia describe their own experiences, before and after placing their relative in a nursing home. BACKGROUND: In the Western world and with a growing population of older people, the number of persons with dementia increases. Family members often become carers in their own homes creating stressful and exhausting situation that eventually leads to relocating the person to a nursing home. This may lead to troubled conscience among family members...
January 2, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27999771/validation-of-evidence-based-fall-prevention-programs-for-adults-with-intellectual-and-or-developmental-disorders-a-modified-otago-exercise-program
#17
Mindy Renfro, Donna B Bainbridge, Matthew Lee Smith
INTRODUCTION: Evidence-based fall prevention (EBFP) programs significantly decrease fall risk, falls, and fall-related injuries in community-dwelling older adults. To date, EBFP programs are only validated for use among people with normal cognition and, therefore, are not evidence-based for adults with intellectual and/or developmental disorders (IDD) such as Alzheimer's disease and related dementias, cerebral vascular accident, or traumatic brain injury. BACKGROUND: Adults with IDD experience not only a higher rate of falls than their community-dwelling, cognitively intact peers but also higher rates and earlier onset of chronic diseases, also known to increase fall risk...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27997604/physical-activity-in-community-dwelling-older-people-a-systematic-review-of-reviews-of-interventions-and-context
#18
Olawale Olanrewaju, Sarah Kelly, Andy Cowan, Carol Brayne, Louise Lafortune
BACKGROUND: The promotion and maintenance of higher physical activity (PA) levels in the older population is an imperative for cognitive and healthy ageing but it is unclear what approaches are best suited to achieve this for the increasing number of older people living in the community. Effective policies should be informed by robust, multi-disciplinary and multi-dimensional evidence, which not only seeks what works, but in 'what context? In addition to evidence on the efficacy and effectiveness of PA for maintaining cognitive health, social contexts such as 'how do we actually get older people to partake in PA?' and 'how do we sustain that activity long-term?' also need highlighting...
2016: PloS One
https://www.readbyqxmd.com/read/27990426/instructors-perceptions-of-mostly-seated-exercise-classes-exploring-the-concept-of-chair-based-exercise
#19
Katie R Robinson, Tahir Masud, Helen Hawley-Hague
Chair based exercise (CBE) can be used to engage older adults unable to take part in standing exercise programmes. Defining and understanding the context of CBE have been acknowledged as a challenge. We explore instructor experiences of delivering mostly seated exercise classes for older people and how this helps us to further understand the concept of CBE. We extracted qualitative data from a cross-sectional survey with 731 exercise instructors. 378 delivered mostly seated classes and 223 of those instructors provided qualitative data...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27986794/characteristics-of-activities-for-persons-with-dementia-at-the-mild-moderate-and-severe-stages
#20
Natalie G Regier, Nancy A Hodgson, Laura N Gitlin
PURPOSE: To understand activity in dementia care, we examine relationships of disease stage with types and characteristics of meaningful activities (cueing needs, help with initiation, and recommended engagement time) provided in a home-based intervention trial designed to reduce behavioral symptoms. DESIGN AND METHODS: Data involved 158 activity prescriptions or written documents detailing prescribed activities, cueing needs, and engagement goals designed by occupational therapists for 56 families...
December 16, 2016: Gerontologist
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