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Jeffrey A Cadeddu
No abstract text is available yet for this article.
June 2018: Journal of Urology
Lifei Yang, Jianwen Lu, Yue Wang, Mei Zhang, Yuan Shi, Shasha Wei, Peng Liu, Zheng Wu, Yi Lv, Rongqian Wu
The rat model of orthotopic liver transplantation (OLT) is essential for transplant research. It is a very sophisticated animal model and requires a steep learning curve. The introduction of the cuff technique for anastomosis of the portal vein (PV) and infrahepatic vena cava (IHVC) has significantly simplified the transplant procedure in rats. However, due to the short anterior wall of the recipients' suprahepatic vena cava (SHVC), the cuff technique is very difficult to use for the reconstruction of the SHVC...
March 19, 2018: Journal of Visualized Experiments: JoVE
Luzia Toselli, Marcelo Martinez-Ferro, Guillermo Cervio, Dillon Kwiat, Jill Imamura-Ching, Claire E Graves, Brandon Gaston, Michael Harrison
INTRODUCTION: Magnamosis forms a compression anastomosis using self-aligning magnetic Harrison rings. The device has been approved by the Food and Drug Administration for first-in-human testing and has been applied in adults for intestinal anastomosis during urologic reconstructions. We now report the first cases of magnamosis to functionally undivert the fecal stream from a previously created loop ileostomy in pediatric patients. MATERIALS AND METHODS: Case 1: A 4-year-old male underwent a diverting loop ileostomy for malignant bowel obstruction...
December 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Claire E Graves, Catherine Co, Ryan S Hsi, Dillon Kwiat, Jill Imamura-Ching, Michael R Harrison, Marshall L Stoller
BACKGROUND: Magnetic compression anastomosis (magnamosis) uses a pair of self-centering magnetic Harrison Rings to create an intestinal anastomosis without sutures or staples. We report the first-in-human case series using this unique device. STUDY DESIGN: We conducted a prospective, single-center, first-in-human pilot trial to evaluate the feasibility and safety of creating an intestinal anastomosis using the Magnamosis device. Adult patients requiring any intestinal anastomosis to restore bowel continuity were eligible for inclusion...
November 2017: Journal of the American College of Surgeons
Robert M Dorman, Kaveh Vali, Carroll M Harmon, Mario Zaritzky, Kathryn D Bass
We describe the treatment of a patient with long-gap esophageal atresia with an upper pouch fistula, mircogastria and minimal distal esophageal remnant. After 4.5 months of feeding via gastrostomy, a proximal fistula was identified by bronchoscopy and a thoracoscopic modified Foker procedure was performed reducing the gap from approximately 7-5 cm over 2 weeks of traction. A second stage to ligate the fistula and suture approximate the proximal and distal esophagus resulted in a gap of 1.5 cm. IRB and FDA approval was then obtained for endoscopic placement of 10-French catheter mounted magnets in the proximal and distal pouches promoting a magnetic compression anastomosis (magnamosis)...
May 2016: Pediatric Surgery International
Xiaopeng Yan, Yanfeng Gao, Yuliang Zou, Fei Xue, Huan Yang, Jianpeng Li, Guangbin Zhao, Jianwen Lu, Xianghua Xu, Yi Lu
The magnamosis device for stage-one repair of the rectovaginal tistula consists of two arc magnets. Drawing the interrupting thread along the fistula margin via the vaginal side, and pulling the string to arrange the magnets at the fistula base along the long axis of the vagina, we made the magnamosis device automatically clipped to seal the fistula. After removing the threads we kept the device for 2-4 weeks till the natural detachment of it when the compressed tissue in between healed after vascular necrosis...
October 2015: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
Hongke Zhang, Yi Lv, Chang Liu, Liang Yu, Xuemin Liu, Dinghui Dong, Feng Ma, Haohua Wang
A new anastomat for digestive tract operations, based on the magnetic compressive technique and mechanical transmission mechanism, is composed of a removable head and a reusable body. The head includes two parts: the proximal end can be fixed to the body, and the distal end could be used for performing a purse string suture. The procedure of anastomosis is similar to that of the stapler, and the anastomoses is established using a pair of magnetic rings. The instrument makes magnamosis more simple and feasible, and it would facilitate the clinical application...
September 2015: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
Fei Xue, Hong-Chang Guo, Jian-Peng Li, Jian-Wen Lu, Hao-Hua Wang, Feng Ma, Ya-Xiong Liu, Yi Lv
AIM: To investigate the optimal magnetic pressure and provide a theoretical basis for choledochojejunostomy magnetic compressive anastomosis (magnamosis). METHODS: Four groups of neodymium-iron-boron magnets with different magnetic pressures of 0.1, 0.2, 0.3 and 0.4 MPa were used to complete the choledochojejunostomy magnamosis. Twenty-six young mongrel dogs were randomly divided into five groups: four groups with different magnetic pressures and 1 group with a hand-suture anastomosis...
February 21, 2016: World Journal of Gastroenterology: WJG
Hao Jiang, Shijie Chen, Shad Kish, Lokkee Loh, Junmin Zhang, Xiaorong Zhang, Dillon Kwiat, Michael Harrison, Shuvo Roy
Anastomosis is a common surgical procedure using staples or sutures in an open or laparoscopic surgery. A more effective and much less invasive alternative is to apply the mechanical pressure on the tissue over a few days [1]. Since the pressure is produced by the attractive force between two permanent magnets, the procedure is called magnamosis[1]. To ensure the two magnets are perfectly aligned during the surgery, a miniaturized batteryless Radio Frequency IDentification (RFID) tag is developed to wirelessly telemeter the status of a pressure sensitive mechanical switch...
2014: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Katie W Russell, Michael D Rollins, G Peter Feola, Eric R Scaife
We report a case of rectal atresia treated using magnets to create a rectal anastomosis. This minimally invasive technique is straightforward and effective for the treatment of rectal atresia in children.
August 5, 2014: BMJ Case Reports
Xiaopeng Yan, Chao Fan, Jia Ma, Jianhui Li, Dinghui Dong, Haohua Wang, Feng Ma, Xinglong Zheng, Yi Lv
BACKGROUND AND AIMS: Installing the transjugular intrahepatic portosystemic shunt for portal hypertension is relatively safe, but complications are still high. To explore a new method of portacaval shunt, the magnetic compression technique was introduced into the shunting procedure. METHODS: A portal-inferior vena cava shunt was performed on 6 male mongrel dogs by two hemocompatible Nd-Fe-B permanent magnets, parent and daughter. The parent magnet was applied to the inferior vena cava guided by a catheter through the femoral vein...
2013: PloS One
J Wall, M Diana, J Leroy, V Deruijter, K D Gonzales, V Lindner, M Harrison, J Marescaux
BACKGROUND AND STUDY AIMS: MAGNAMOSIS forms a compression anastomosis using self-assembling magnetic rings that can be delivered via flexible endoscopy. The system has proven to be effective in full-thickness porcine small-bowel anastomoses. The aim of this study was to show the feasibility of the MAGNAMOSIS system in hybrid endoscopic colorectal surgery and to compare magnetic and conventional stapled anastomoses. METHODS: A total of 16 swine weighing 35 - 50 kg were used following animal ethical committee approval...
August 2013: Endoscopy
Ibrahim Uygun, Mehmet H Okur, Yilmaz Arayici, Aysenur Keles, Hayrettin Ozturk, Selcuk Otcu
BACKGROUND: Magnetic compression anastomoses (magnamosis) have been previously described for gastrointestinal, biliary, urinary, and vascular anastomoses. Objectives. Herein, the authors report the creation of a magnetic compression colostomy (magnacolostomy) using a simple technique in rats. MATERIAL AND METHODS: Animals were randomized into two groups (n = 8, each): a magnetic colostomy (MC) group and a control surgical tube colostomy (SC) group. In the MC group, the first magnetic ball (3 mm) was rectally introduced into the rat colon...
May 2012: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Kelly D Gonzales, Geoffrey Douglas, Kullada O Pichakron, Dillon A Kwiat, Salvador Guevara Gallardo, Jose Luis Encinas, Shinjiro Hirose, Michael R Harrison
PURPOSE: Magnamosis creates a secure sutureless anastomosis through magnetic compression. In this study, we further develop and test delivery devices capable of creating a secure duodeno-colonic anastomosis using available minimally invasive endoscopic techniques. METHODS: Eight pigs underwent general anesthesia. Colonoscopy was used to deliver 1 magnetic ring to the hepatic flexure. Simultaneously, upper endoscopy delivered the other magnetic ring into the duodenum using a variety of techniques...
June 2012: Journal of Pediatric Surgery
Ibrahim Uygun, Mehmet Hanifi Okur, Hasan Cimen, Aysenur Keles, Ozben Yalcin, Hayrettin Ozturk, Selcuk Otcu
OBJECTIVE: To report the first creation of magnetic compression cystostomy (magnacystostomy) using an easy and simple new technique in rats. Magnetic compression anastomoses (magnamosis) have been previously described for gastrointestinal, biliary, urinary, and vascular anastomoses. METHODS: Female rats were randomized into 2 groups (n = 10 each): a magnetic cystostomy group and a formal surgical cystostomy group as the control group. In the magnetic cystostomy group, a very small cylindrical magnet was inserted into the bladder...
March 2012: Urology
Joël Leroy, Silvana Perretta, Michele Diana, James Wall, Veronique Lindner, Michael Harrison, Jacques Marescaux
INTRODUCTION: While experimental natural orifice transluminal endoscopic surgery (NOTES) sigmoid colectomies have been reported, pure NOTES anastomoses are restricted by the limited reach of commercially available circular staplers. MAGNAMOSIS is a set of self-orienting magnetic rings that can be delivered endoluminally throughout the colon to generate a compression anastomosis. Aim. To assess the feasibility of a pure NOTES transrectal (TR) and transgastric (TG) approach to perform any segmental colectomy...
June 2012: Surgical Innovation
Michele Diana, James Wall, Silvana Perretta, Bernard Dallemagne, Kelly D Gonzales, Michael R Harrison, Vincent Agnus, Luc Soler, Stephan Nicolau, Jacques Marescaux
OBJECTIVE: This study aimed to assess the feasibility of a totally endoscopic enteral bypass using a self-orienting, dual ring, magnetic anastomosis system (MAGNAMOSIS) guided by a magnetic tracking system (3D METRIS). MATERIALS AND METHODS: In an anesthetized pig, 2 endoscopes were advanced, one each into the stomach and the colon. Both endoscopes were equipped with a MAGNAMOSIS ring secured with an endoscopic snare and a 3D METRIS within one working channel. The whole procedure was followed laparoscopically...
December 2011: Surgical Innovation
Silvana Perretta, James K Wall, Bernard Dallemagne, Michael Harrison, François Becmeur, Jacques Marescaux
BACKGROUND: Esophageal reconstruction presents a significant clinical challenge in patients ranging from neonates with long-gap esophageal atresia to adults after esophageal resection. Both gastric and colonic replacement conduits carry significant morbidity. As emerging organ-sparring techniques become established for early stage esophageal tumors, less morbid reconstruction techniques are warranted. We present two novel endoscopic approaches for esophageal lengthening and reconstruction in a porcine model...
October 2011: Surgical Endoscopy
Kullada O Pichakron, Eric B Jelin, Shinjiro Hirose, Patrick F Curran, Ramin Jamshidi, Jacob T Stephenson, Richard Fechter, Michael Strange, Michael R Harrison
BACKGROUND: Previously we demonstrated the safety and patency of a magnetic compression anastomosis (magnamosis). We present the further development of this technique, with specific focus on optimizing device design for minimally invasive magnamosis. STUDY DESIGN: The magnamosis device was designed to incorporate 3 features: 2 convex-concave radially symmetric halves that magnetically self-align, a central channel for immediate patency, and specially engineered radial topography of the mating surfaces to promote gradual remodeling...
January 2011: Journal of the American College of Surgeons
Yik Hong Ho, Mohamed Ahmed Tawfik Ashour
Colorectal anastomotic leak remains one of the most feared post-operative complications, particularly after anterior resection of the rectum with, the shift from abdomino-peritoneal resections to total mesorectal excision and primary anastomosis. The literature fails to demonstrate superiority of stapled over hand-sewn techniques in colorectal anastomosis, regardless of the level of anastomosis, although a high stricture rate was noted in the former technique. Thus, improvements in safety aspects of anastomosis and alternatives to hand-sewn and stapled techniques are being sought...
April 7, 2010: World Journal of Gastroenterology: WJG
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