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https://www.readbyqxmd.com/read/29141064/port-wine-stains-a-focused-review-on-their-management
#1
Katelyn Mariko Updyke, Amor Khachemoune
<p>Port-wine stain (PWS) is the second most common congenital vascular malformation characterized as ectatic capillaries and venules in the dermis that clinically appears as a deep red to purple patch on the skin. Typically, PWS progressively darken and may become hypertrophic or nodular without treatment. There are several treatment options available for PWS from topical antiangiogenic agents to laser therapies. Vascular-specific lasers are the gold standard in treating PWS and classically pulsed dye lasers are usually the treatment of choice...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29141060/efficacy-of-low-fluence-nd-yag-1064-nm-laser-for-the-treatment-of-post-inflammatory-hyperpigmentation-in-the-axillary-area
#2
Sahar Ghannam, Fatemah K Al Otabi, Konstantin Frank, Sebastian Cotofana
<p>OBJECTIVE: Post-inflammatory hyperpigmentation results in aesthetically unpleasant discoloration of the skin in the affected area. The efficacy of low-fluence Q-switched 1064-nm Nd:YAG laser has so far not been evaluated for the treatment of the axilla. This observational study was designed to evaluate whether the application of the laser treatment can satisfactorily reduce axillary hyperpigmentation. MATERIAL AND METHODS: 17 females (mean age, 34.27 ± 9.24; range, 19-48) were treated in a single center between 2014 and 2016 for post-inflammatory hyperpigmentation of the axillary area...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29141056/in-vivo-histological-analysis-of-a-fractional-co2-laser-system-intended-for-treatment-of-soft-tissue
#3
Elisabeth Hurliman, Brian Zelickson, Jeffrey Kenkel
<p>BACKGROUND: Fractional ablative lasers have been shown to be safe and effective for improving wrinkles, scars, skin texture, and dyspigmentation. However, the exact effects of this technology in vivo on epidermal and dermal skin constituents have not been delineated. This study evaluated the in vivo histological effects over time of treatment with a fractional ablative CO2 system, using different treatment parameters. MATERIALS AND METHODS: Healthy adult volunteers were enrolled in this multicenter clinical study...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29141054/managing-seborrheic-keratoses-evolving-strategies-for-optimizing-patient-outcomes
#4
Geraldine Cheyana Ranasinghe, Adam J Friedman
<p>The seborrheic keratosis is the most common benign skin tumor of middle-aged and elderly adults, affecting nearly 83 million individuals in the US alone. Although these are benign lesions, many patients still undergo some form of treatment. Clinicians are frequently presented with a challenge when determining whether to remove a seborrheic keratosis, and which treatment modality to use when doing so. The most commonly used method of removal is cryotherapy, however there are numerous other options that can be employed with varying degrees of efficacy...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29141048/microcirculation-in-open-vs-minimally-invasive-dorsal-stabilization-of-thoracolumbar-fractures
#5
Bergita Ganse, Miguel Pishnamaz, Philipp Kobbe, Christian Herren, Gertraud Gradl-Dietsch, Franziska Böhle, Bernd Johannes, Bong-Sung Kim, Klemens Horst, Matthias Knobe
Standard open and percutaneous minimally invasive surgical procedures co-exist in the treatment of fractures of the thoracolumbar spine. Shorter skin incisions just above the pedicles are used in minimally invasive procedures. Full-length skin incisions and invasive preparations are applied in the standard open approach. While both methods show equivalent rates of intraoperative surgical complications and comparable clinical and radiological outcomes, blood loss and operation time have shown to be decreased in minimally invasive treatment...
2017: PloS One
https://www.readbyqxmd.com/read/29140866/one-thousand-five-hundred-fifty-nanometer-erbium-doped-nonablative-fractional-laser-for-the-treatment-of-striae-distensae-in-patients-of-skin-of-color-fitzpatrick-skin-types-iv-vi
#6
Kelly K Park, Erin Roberts, Rebecca C Tung
No abstract text is available yet for this article.
November 14, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29138594/prevention-and-treatment-of-acute-and-chronic-radiodermatitis
#7
Sophie Seité, René-Jean Bensadoun, Jean-Michel Mazer
More than half the number of patients with cancer, who are treated with radiotherapy, will have radiodermatitis at some point during their treatment. Radiodermatitis either occurs early on in the treatment period or appears months or up to several years later. Acute radiodermatitis is a burn injury that varies in severity according to both treatment and inherent patient factors. Most acute radiodermatitis reactions resolve after several weeks but some reactions persist and can cause complications. Late-onset radiodermatitis is characterized by telangiectasia that forms on atrophic and fragile skin...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/29138062/topical-calcipotriol-prior-to-ablative-fractional-laser-assisted-photodynamic-therapy-enhances-treatment-outcomes-for-actinic-keratosis-in-fitzpatrick-grades-iii-v-skin-a-prospective-randomized-clinical-trial
#8
Jeong-Wan Seo, Ki-Hoon Song
No abstract text is available yet for this article.
November 11, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29135894/deferoxamine-preconditioning-of-irradiated-tissue-improves-perfusion-and-fat-graft-retention
#9
John Flacco, Natalie Chung, Charles P Blackshear, Dre Irizarry, Arash Momeni, Gordon K Lee, Dung Nguyen, Geoffrey C Gurtner, Michael T Longaker, Derrick C Wan
BACKGROUND: Radiation therapy is a mainstay in the treatment of many malignancies, but collateral damage to surrounding tissue, with resultant hypovascularity, fibrosis, and atrophy, can be difficult to reconstruct. Fat grafting has been shown to improve the quality of irradiated skin, but volume retention of the graft is significantly decreased. Deferoxamine (DFO) is a FDA-approved iron-chelating medication for acute iron intoxication and chronic iron overload that has also been shown to increase angiogenesis...
November 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29131366/successful-and-safe-use-of-q-switched-lasers-in-the-treatment-of-nevus-of-ota-in-children-with-phototypes-iv-vi
#10
Daniel A Belkin, Hana Jeon, Elliot Weiss, Jeremy A Brauer, Roy G Geronemus
OBJECTIVE: Nevus of Ota represents congenital dermal melanocytosis in a trigeminal distribution, most commonly occurring in Asian individuals and other individuals with skin of color. Evidence suggests early treatment is beneficial. Multiple reports have shown efficacy and safety of Q-switched laser treatment in adults. There is little data on children and in non-Asian skin types. This series was done to demonstrate safe and effective use of Q-switched laser therapy in children of multiple skin types...
November 13, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29124708/phototherapy-in-atopic-dermatitis
#11
José María Ortiz-Salvador, Amparo Pérez-Ferriols
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. Currently management of AD includes avoidance of triggering factors, skin care aiming to compensate the skin barrier defects, anti-inflammatory therapy (mostly topical corticosteroids and topical calcineurin inhibitors). When these first-line approaches are unsuccessful, systemic treatment or phototherapy ought to be carried out as next line of defence. Current phototherapy modalities for AD include broadband UVB (290-320 nm), narrowband UVB (311-313 nm), UVA-1 therapy (340-400 nm), UVA therapy plus 8-methoxypsoralens (PUVA), 308 nm excimer laser (EL) and Full spectrum light (FSL)...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29116332/-therapy-of-scars-with-lasers
#12
REVIEW
G G Gauglitz, J Pötschke, M T Clementoni
Scar formation is the consequence of trauma to the skin that affects the deep parts of the dermis. Different scar types like immature, mature, atrophic, hypertrophic, or keloid scars can develop depending on factors like age, anatomic localization, cause of trauma, the course of the healing process, and individual predispositions. Keloids and hypertrophic scars are often associated with itching, pain, tautness of the skin, and functional impairments, thus, leading to significantly reduced quality of life in some patients...
November 7, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29111604/a-comparitive-study-with-a-755%C3%A2-nm-picosecond-alexandrite-laser-with-a-diffractive-lens-array-and-a-532%C3%A2-nm-1-064%C3%A2-nm-nd-yag-with-a-holographic-optic
#13
Emil Tanghetti, John Jennings
BACKGROUND AND OBJECTIVES: This study was performed to better understand the cutaneous effects of using a fractional picosecond laser at 755 nm with a diffractive lens array and a picosecond Nd:YAG laser at 532 mn and 1,064 nm with a holographic optic. We characterized the injuries created by these devices on skin clinically and histologically over 24 hours. With this information we modeled the effects of these devices on a cutaneous target. METHODS: Eight patients, representing Fitzpatrick skin types I-VI, were treated on their backs with a picosecond Alexandrite laser with a diffractive lens array, as well as a picosecond Nd:YAG laser at 532 nm and 1,064 nm with a holographic optic...
November 7, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29110125/-laser-assisted-blepharoplasty
#14
REVIEW
R Thiesmann
Blepharoplasty is one of the most frequently performed plastic cosmetic interventions. For this purpose the CO2 laser is an instrument that can be used as a laser scalpel to cut as well as in its ablative function to remove skin irregularities, such as scars and tumors and also to treat changes of the skin due to aging. Fractionated laser irradiation reduces the duration of skin redness and the postoperative rehabilitation time after a resurfacing. The advantages of the CO2 laser are a gentle intraoperative preparation and less postoperative swelling due to an additional cauterization of blood vessels...
November 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29110043/-axillary-and-perimamillary-fox-fordyce-disease-apocrine-miliaria-in-a%C3%A2-19-year-old-woman
#15
S Hanner, R Schneiderbauer, A Enk, F Toberer
Fox-Fordyce disease (FFD), also known as apocrine miliaria, is a rare and chronic skin disease characterized by itching and skin-colored, light brown or yellowish papules. FFD typically affects postpubertal young women between 13 and 35 years. The etiology is not completely known, but a hormonal component is in discussion. Furthermore, exacerbating factors like laser hair removal and hyperhidrosis have been described. Treatment of FFD is quite challenging, as the reported modalities mostly show limited success...
November 6, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29105868/successful-treatment-of-disseminated-nocardiosis-caused-by-nocardia-veterana-in-a-dog
#16
S Yaemsiri, J E Sykes
A 5-year-old male castrated Lhasa Apso cross was evaluated for a 1-month history of inappetence, lethargy, gagging, and progressive right thoracic limb lameness. Synovial fluid analysis revealed nonseptic suppurative inflammation, and a diagnosis of immune-mediated polyarthritis (IMPA) was made. After 3 months of treatment with prednisone and later cyclosporine, the dog developed multiple firm cutaneous and subcutaneous masses and a focal mass within the jejunum. Cultures of blood, urine, skin lesions, and the jejunal mass identified Nocardia veterana by matrix-absorption laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) and allowed for earlier identification of the organism compared to more traditional secA1 gene sequencing...
November 4, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29105473/-effect-of-electroacupuncture-at-neiguan-pc-6-on-skin-microcirculation-blood-perfusion-volume-of-heart-related-acupoints-and-heart-irrelevant-acupoints-in-myocardial-ischemia-rats
#17
Jian Dai, Bo Ji, Ya-Wen Lu, Guo-Zhen Zhao, Dan Wang, Ming-Na Yan, Hong-Xin Bai, Xiao-Min Sun, Min You, Jiao-Juan Wu, Meng-Wei Guo, Zhi-Gang Li, Kai Cheng
OBJECTIVE: To observe the effect of low-frequency or high-frequency electroacupuncture (EA) stimulation of "Neiguan" (PC 6) on changes of skin blood perfusion volume of heart-related and heart-irrelevant acupoints in rats with normal or ischemic myocardium. METHODS: Wistar rats were randomly divided into the control, sham-operation, model, low-frequency EA and high-frequency EA groups (n=8 in each group). The myocardial ischemic (MI) model was established by occlusion of the anterior descending branch of the left coronary artery...
October 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29098459/picosecond-532-nm-neodymium-doped-yttrium-aluminium-garnet-laser-a-novel-and-promising-modality-for-the-treatment-of-caf%C3%A3-au-lait-macules
#18
Ofir Artzi, Joseph N Mehrabi, Amir Koren, Roni Niv, Moshe Lapidoth, Assi Levi
Café-au-lait macules (CALMs) present as benign hyperpigmented, well-circumscribed spots on the skin for which many patients seek treatment for aesthetic reasons. The objective of this study is to report our experience in treating CALMs using a picosecond 532-nm neodymium-doped yttrium aluminium garnet (PS 532 nm) laser. This is a retrospective case series of 16 patients with CALMs who were treated by a PS 532-nm laser (1-4 treatments, 4-8 weeks apart). Response as seen on clinical photographs was assessed by two independent dermatologists and graded on a scale of 0 (exacerbation) to 5 (95-100% improvement)...
November 2, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29090468/clinicopathologic-characteristics-of-early-onset-becker-s-nevus-in-korean-children-and-adolescents
#19
Young J Kim, Mi R Roh, Ji H Lee, Jung I Na, Joo Y Ko, Joon M Jung, Jong H Lee, Sung E Chang
BACKGROUND: Becker's nevus (BN) presents as a hairy patch or plaque with or without proliferation of the dermal smooth muscles. BN has been described as acquired as found in a similar entity, congenital smooth muscle hamartoma (CSMH). This study was aimed at evaluating the clinicopathological aspects of BN in Korean cases in differential diagnosis with CSMH. METHODS: We performed a retrospective study of 103 patients histopathologically diagnosed as having BN or CSMH...
October 31, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29080008/objective-evaluation-of-the-efficacy-of-a-non-ablative-fractional-1565%C3%A2-nm-laser-for-the-treatment-of-deliberate-self-harm-scars
#20
Anne Guertler, Markus Reinholz, Julian Poetschke, Stephanie Steckmeier, Hannah Schwaiger, Gerd G Gauglitz
Scars resulting from deliberate self-harm (DSH) represent therapeutically challenging forms of scarring due to their highly variable patterns, with no official therapeutic guidelines available. In this pilot study, we aimed to evaluate the effectiveness and safety of a non-ablative fractional Er:glass 1565 nm laser, as a potential new, minimal-invasive approach for the improvement of DSH scars. Sixteen Caucasians suffering from mature DSH scars were included in this clinical study. Patients received a total of three treatments using a non-ablative fractional 1565 nm Er:glass laser every 4 weeks, employing two passes (300 μbeams/cm(2), 40 mJ, onto the scar; 150 μbeams/cm(2), 50 mJ, overall area)...
October 27, 2017: Lasers in Medical Science
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