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https://www.readbyqxmd.com/read/27911144/comparison-of-pulsed-dye-laser-versus-combined-pulsed-dye-laser-and-nd-yag-laser-in-the-treatment-of-inflammatory-acne-vulgaris
#1
Manal Mohamed Salah El Din, Nevien Ahmed Samy, Amira Eid Salem
BACKGROUND: Both pulsed dye laser and combined 585/1,064-nm (sequential dual-wave-length PDL and Nd:YAG) laser improves inflammatory skin disorders including acne vulgaris. OBJECTIVE: To compare the efficacy of 585 nm pulsed dye laser versus sequential dual-wave-length PDL and Nd:YAG in treatment of acne vulgaris. PATIENTS AND METHOD: Thirty patients complaining of acne vulgaris were treated with a single pass of PDL alone on half of the face and a single pass of combined 585/1064-nm laser on the other half for four treatment sessions at 2 weeks interval, then assessed by the count and severity of the acne lesions & digital camera photographs Results: The study showed that inflammatory acne lesions count was significantly reduced by 82...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27911117/are-lasers-superior-to-lights-in-the-photoepilation-of-fitzpatrick-v-and-vi-skin-types-a-comparison-between-nd-yag-laser-and-intense-pulsed-light
#2
Bibilash Bs, Ravi Kumar Chittoria, Devinder Mohan Thappa, Devi Prasad Mohapatra, Friji M T, Dineshkumar S, Sandhya Pandey
BACKGROUND AND OBJECTIVES: There are no large volume comparative studies available to compare the efficacy of lasers over lights for hair removal in Fitzpatrick V and VI skin types. This study is designed to compare the efficacy of Nd:YAG Laser versus IPL in the darker skin types. STUDY DESIGN/MATERIALS AND METHODS: Thirty nine patients included in Group-1 were treated with Nd:YAG and 31 in group-2 with IPL. Both groups received 5 sessions of treatment. The hair counts were assessed using digital photography and manual counting method before and after treatment and results were analysed...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27899298/mechanisms-and-time-course-of-menthol-induced-cutaneous-vasodilation
#3
Daniel H Craighead, Nathaniel B McCartney, James H Tumlinson, Lacy M Alexander
Menthol is a vasoactive compound that is widely used in topical analgesic agents. Menthol induces cutaneous vasodilation, however the underlying mechanisms are unknown. Determining the rates of appearance and clearance of menthol in the skin is important for optimizing topical treatment formulation and dosing. The purpose of this study was to determine the mechanisms contributing to menthol-mediated cutaneous vasodilation and to establish a time course for menthol appearance/clearance in the skin. Ten young (23±1years, 5 males 5 females) subjects participated in two protocols...
November 26, 2016: Microvascular Research
https://www.readbyqxmd.com/read/27896221/microvascular-blood-flow-improvement-in-hyperglycemic-obese-adult-patients-by-hypocaloric-diet
#4
T Mastantuono, M Di Maro, M Chiurazzi, L Battiloro, N Starita, G Nasti, D Lapi, L Iuppariello, M Cesarelli, G D'Addio, A Colantuoni
The present study was aimed to assess the changes in skin microvascular blood flow (SBF) in newly diagnosed hyperglycemic obese subjects, administered with hypocaloric diet. Adult patients were recruited and divided in three groups: NW group (n=54), NG (n=54) and HG (n=54) groups were constituted by normal weight, normoglycemic and hyperglycemic obese subjects, respectively. SBF was measured by laser Doppler perfusion monitoring technique and oscillations in blood flow were analyzed by spectral methods under baseline conditions, at 3 and 6 months of dietary treatment...
November 2016: Translational Medicine @ UniSa
https://www.readbyqxmd.com/read/27888888/laser-assisted-delivery-to-treat-facial-scars
#5
REVIEW
Jill S Waibel, Ashley Rudnick
Treatment of facial scars is a multispecialty endeavor for optimal patient recovery. One new innovation helping in facial scar treatments are lasers. Fractional laser predictably (tunable) disrupts the barrier of the skin creating deep channels that allow the delivery of drug and cellular materials; this is called laser-assisted drug delivery (LAD). Without exception thus far, LAD has been found to enhance the local uptake of any drug or substance applied to the skin. These zones may be used postoperatively to deliver drugs and other substances to create an enhanced scar therapeutic response to drug or substance applied to the skin...
February 2017: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/27885522/efficacy-and-safety-of-fractional-co2-laser-versus-fractional-er-yag-laser-in-the-treatment-of-facial-skin-wrinkles
#6
Reza M Robati, Elmira Asadi
Ablative fractional lasers were introduced for treating facial rhytides. Few studies have compared fractional CO2 and Er:YAG lasers on cutaneous photodamages by a split trial. The aim of the present study was to compare these modalities in a randomized controlled double-blind split-face design with multiple sessions and larger sample size compared to previous studies done before. Forty patients with facial wrinkles were enrolled. Patients were randomly assigned to receive three monthly treatments on each side of the face, one with a fractional CO2 and one with a fractional Er:YAG laser...
November 24, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27885520/the-effect-of-pre-operative-topical-anaesthetic-cream-on-the-ablative-width-and-coagulative-depth-of-ablative-fractional-resurfacing-laser
#7
Preawphan Punyaratabandhu, Rungsima Wanitphakdeedecha, Penvadee Pattanaprichakul, Panitta Sitthinamsuwan, Weeranut Phothong, Sasima Eimpunth, Visnu Lohsiriwat, Woraphong Manuskiatti
Topical anaesthetic cream (TAC) is commonly used as a pre-treatment of ablative fractional resurfacing (AFR) laser. Most of anaesthetic cream contains distilled water as major component. Therefore, pre-operative TAC may interfere the photothermal reaction in the skin treated with fractional carbon-dioxide (FCO2) laser and fractional erbium-doped yttrium aluminium garnet (FEr:YAG) laser. The objective of the study was to compare the ablative width (AW) and coagulative depth (CD) of AFR laser with and without pre-treatment with TAC...
November 24, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27885499/the-effects-of-alpha-1-adrenoceptor-blockade-and-angiotensin-converting-enzyme-inhibition-on-central-and-brachial-blood-pressure-and-vascular-reactivity-the-doxazosin-ramipril-study
#8
Andreas Jekell, Majid Kalani, Thomas Kahan
We aimed to study whether inhibition of the renin-angiotensin-aldosterone system has effects on vascular structure and function beyond the effects on blood pressure reduction alone. Patients with mild-to-moderate hypertension (n = 61, age 54 ± 12 years, 34% women) received the angiotensin converting enzyme inhibitor ramipril 10 mg or the alpha 1-adrenoceptor blocker doxazosin 8 mg double-blind for 12 weeks. Aortic blood pressure, pulse wave velocity, and augmentation index were assessed by applanation tonometry...
November 24, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27878794/varicosities-of-the-lower-extremity-new-approaches-cosmetic-or-therapeutic-needs
#9
Luca Spinedi, Heiko Uthoff, Sasan Partovi, Daniel Staub
Varicose veins of the lower extremity (VVLE) are a frequently encountered vascular disorder in the general population. The general view that VVLE are a non-serious disease with primarily aesthetic impact is a common misconception, as the disease can have a significant negative impact on generic and disease-specific quality of life. Further, VVLE may be associated with potentially threatening clinical conditions, such as chronic venous ulceration, venous thromboembolism and haemorrhage from ruptured varicose veins...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27873347/infantile-hemangioma-with-minimal-or-arrested-growth-further-observations-on-clinical-and-histopathologic-findings-of-this-unique-but-underrecognized-entity
#10
Ellen Hui Ma, Susan J Robertson, Chung W Chow, Philip S Bekhor
BACKGROUND: Infantile hemangioma (IH) with minimal or arrested growth (IH-MAG) is becoming increasingly recognized in the literature. It is important to be aware of their existence, because the correct diagnosis is essential for prognostication and treatment and, in the case of facial segmental lesions, the direction of further investigations if PHACE (posterior fossa abnormalities and other structural brain abnormalities; hemangioma(s) of the cervical facial region; arterial cerebrovascular anomalies; cardiac defects, aortic coarctation, and other aortic abnormalities; eye anomalies) syndrome or Sturge-Weber syndrome is suspected...
November 22, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27872944/-multiple-eccrine-hidrocystomas-on-the-lower-forehead-and-nose-of-a%C3%A2-60-year-old-man
#11
J K Winkler, W Hartschuh, A Enk, F Toberer
Multiple eccrine hidrocystomas are benign cystic skin lesions which originate from the sweat gland ducts and typically affect women's midfacial area. Sweating may lead to an increase in size of the translucent papules. In some cases hidrocystomas are associated with other diseases such as Parkinson's disease. Treatment options include laser, topical and systemic anticholinergic drugs (glycopyrrolate, clonidine, atropine, and oxybutynin), whereby therapeutic success is limited in most cases.
November 21, 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27859929/does-attenuated-skin-blood-flow-lower-sweat-rate-and-the-critical-environmental-limit-for-heat-balance-during-severe-heat-exposure
#12
Matthew N Cramer, Daniel Gagnon, Craig G Crandall, Ollie Jay
Attenuated skin blood flow (SkBF) is often assumed to impair core temperature (Tc ) regulation. Profound pharmacologically-induced reductions in SkBF (∼85%) lead to impaired sweating but whether the smaller attenuations in SkBF (∼20%) more associated with ageing and certain diseases lead to decrements in sweating and maximum heat loss potential is unknown. Seven healthy males (28 ± 4y) completed a 30-min equilibration period at 41°C and a vapour pressure (Pa ) of 2.57 kPa followed by incremental steps in Pa of 0...
November 11, 2016: Experimental Physiology
https://www.readbyqxmd.com/read/27858258/application-of-reflectance-confocal-microscopy-to-evaluate-skin-damage-after-irradiation-with-an-yttrium-scandium-gallium-garnet-ysgg-laser
#13
Xueping Yue, Hongwei Wang, Qing Li, Linfeng Li
The objective of this study was to observe the characteristics of the skin after irradiation with a 2790-nm yttrium-scandium-gallium-garnet (YSGG) laser using reflectance confocal microscopy (RCM). A 2790-nm YSGG laser was used to irradiate fresh foreskin (four doses, at spot density 3) in vitro. The characteristics of microscopic ablative columns (MAC), thermal coagulation zone (TCZ), and microscopic treatment zones (MTZ) were observed immediately after irradiation using digital microscope and RCM. The characteristics of MAC, TCZ, and MTZ with variations in pulse energy were comparatively analyzed...
November 17, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27854332/fractional-co%C3%A2-laser-pretreatment-facilitates-transdermal-delivery-of-two-vitamin-c-derivatives
#14
Chien-Yu Hsiao, Hsin-Ching Sung, Sindy Hu, Yau-Li Huang, Chun-Hsun Huang
BACKGROUND: Topical vitamin C derivatives have been used to treat melasma and used as a skin whitener. The aim of this study was to compare skin histology and permeation of l-ascorbic acid 2-phosphate sesquimagnesium salt (MAP-1) and magnesium l-ascorbic acid-2-phosphate (MAP-2) after fractional CO₂ laser pretreatment. METHODS: The effect of fractional laser treatment on porcine skin was examined by scanning electron microscopy and confocal laser scanning electron microscopy...
November 16, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27853342/theoretical-review-of-the-treatment-of-pigmented-lesions-in-asian-skin
#15
Taro Kono, Samantha Y Shek, Henry H L Chan, William F Groff, Kotaro Imagawa, Tadashi Akamatsu
Asian skin has a higher epidermal melanin content, making it more likely to develop adverse pigmentary reactions following laser surgery. The nanosecond lasers are the gold standard for the treatment of pigmented lesions, but the risk of complications, such as post-inflammatory hyperpigmentation, is increased in dark-skinned patients. Intense Pulsed Light (IPL) or long-pulsed lasers are available for treating superficial pigmented lesions, and fewer complications are seen when using these devices compared to the nanosecond lasers...
October 1, 2016: Laser Therapy
https://www.readbyqxmd.com/read/27846771/an-8-year-population-description-from-a-national-treatment-centre-on-lymphatic-malformations
#16
Jill Josefine Eliasson, Inanna Weiss, Hans Erik Høgevold, Nina Oliver, Rune Andersen, Kirsti Try, Kim Alexander Tønseth
INTRODUCTION: Lymphatic malformations are rare developmental non-malignant abnormalities that present as masses consisting of abnormal growth of fluid filled channels or spaces in the skin or deep tissue that result in abnormalities of lymphatic flow. They may cause symptoms like pain, recurrent lymphorrea, abnormal bone growth, and disturbance of bodily functions. They may also be a cosmetic problem. The study aims to describe the population with lymphatic malformations (LM) treated at a national referral centre...
November 16, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27843919/rosacea-management
#17
REVIEW
Manal Abokwidir, Steven R Feldman
BACKGROUND: Rosacea is a chronic inflammatory skin condition associated with four distinct subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular. PURPOSE: To review the different kinds of management for all subtypes. METHODS: We divided rosacea management into three main categories: patient education, skin care, and pharmacological/procedural interventions. RESULTS: Flushing is better prevented rather than treated, by avoiding specific triggers, decreasing transepidermal water loss by moisturizers, and blocking ultraviolet light...
September 2016: Skin Appendage Disorders
https://www.readbyqxmd.com/read/27842856/hyaluronan-polymeric-micelles-for-topical-drug-delivery
#18
Daniela Šmejkalová, Tomáš Muthný, Kristina Nešporová, Martina Hermannová, Eva Achbergerová, Gloria Huerta-Angeles, Marek Svoboda, Martin Čepa, Veronika Machalová, Dominika Luptáková, Vladimír Velebný
Nanosized materials offer promising strategy for topical drug delivery due to their enhancing effect on drug percutaneous transport across the stratum corneum barrier. In this work, polymeric micelles made from hydrophobized hyaluronic acid (HA) were probed for skin delivery. Compared to non-polymeric micelle solutions containing similar drug amount, in vitro skin penetration analysis indicated 3 times larger deposition of drug in the epidermis and 6 times larger drug deposition in the dermis after 5h of topical treatment in Franz diffusion cells...
January 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27833475/noninvasive-transdermal-vaccination-using-hyaluronan-nanocarriers-and-laser-adjuvant
#19
Ki Su Kim, Hyemin Kim, Yunji Park, Won Ho Kong, Seung Woo Lee, Sheldon J J Kwok, Sei Kwang Hahn, Seok Hyun Yun
Vaccines are commonly administered by injection using needles. Although transdermal microneedles are less-invasive promising alternatives, needle-free topical vaccination without involving physical damage to the natural skin barrier is still sought after as it can further reduce needle-induced anxiety and simply administration. However, this long-standing goal has been elusive since the intact skin is impermeable to most macromolecules. Here, we show an efficient, non-invasive transdermal vaccination in mice by employing two key innovations: first, the use of hyaluronan (HA) as vaccine carriers and, second, non-ablative laser adjuvants...
April 19, 2016: Advanced Functional Materials
https://www.readbyqxmd.com/read/27827560/development-of-a-novel-automated-hair-counting-system-for-the-quantitative-evaluation-of-laser-hair-removal
#20
Hyoung-Woo Lim, Minwoo Cho, Dong-Hun Lee, Wooseok Koh, Youdan Kim, Jin Ho Chung, Sungwan Kim
OBJECTIVE: We aimed to develop and validate a novel computer-assisted automated hair counting system for the quantitative evaluation of laser hair removal (LHR). METHODS: We developed a computer-aided image processing system to count hairs on shaved skin and validated its performance through clinical trials. Five volunteers of Fitzpatrick skin type III-IV volunteered and were tested on both thighs. The system automatically detects hair and places a "+" sign on each hair site for every positive detection...
November 3, 2016: Photomedicine and Laser Surgery
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