keyword
https://read.qxmd.com/read/38703948/cardiovascular-benefits-of-resistance-exercise-it-s-time-to-prescribe
#21
REVIEW
Hélder Dores, Mafalda Antunes, Daniel Caldeira, Hugo V Pereira
Despite the well-known health benefits of regular physical activity, sedentary behavior and physical inactivity remain a real global pandemic. Exercise is associated with increased life expectancy, improved quality of life and prevention of multiple diseases. Although less implemented in practice compared to aerobic exercise, recent evidence shows that resistance exercise (RE) is also responsible for various benefits, including improvements in body composition, control of several cardiovascular (CV) risk factors, and reduction of CV outcomes...
May 2, 2024: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://read.qxmd.com/read/38703883/short-term-outcomes-of-transcatheter-aortic-valve-replacement-in-low-risk-patients-with-pure-severe-aortic-regurgitation
#22
JOURNAL ARTICLE
Lin Da-Wei, Weng Zi-Long, Fang Yan-Xing, Fan Jia-Ning, Qi Yi-Ming, Zhan Zhi, Long Yu-Liang, Pan Wen-Zhi, Zhou Da-Xin, Ge Jun-Bo
Transcatheter aortic valve replacement (TAVR) has emerged as an alternative treatment for patients with pure severe aortic regurgitation (PSAR) who are contraindicated for surgery or have a high surgical risk. However, the therapeutic efficacy and safety of TAVR in low Society of Thoracic Surgeons score (STS) risk patients remain to be clarified. This study aimed to explore the feasibility of TAVR treatment in different STS risk patients and to compare the adverse events between the groups. In this study, patients with PSAR who underwent TAVR at Zhongshan Hospital, Fudan University, China, during the inclusion period were included and categorized into three groups based on STS scores...
May 2, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38703233/factors-associated-with-food-label-use-focus-on-healthy-aspects-of-orthorexia-and-orthorexia-nervosa
#23
JOURNAL ARTICLE
Ezgi Bellikci-Koyu, Yasemin Karaağaç, Armağan Aytuğ Yürük
PURPOSE: This study aimed to investigate the potential relationships between the use of different section of food label, and healthy and pathological aspects of orthorexia among adults. METHODS: This cross-sectional study was conducted using an online survey (n = 1326). Inclusion criteria were being 19-64 years and graduated from at least primary school. Pregnant and lactating women were excluded. Data were collected using questionnaire including socio-demographic variables, lifestyle factors, body weight and height, frequency of reading different sections of food label ("always", "when buying a food for the first time", "when comparing similar packaged foods", "rarely", "never"), food label literacy, and Teruel Orthorexia Scale...
May 4, 2024: Eating and Weight Disorders: EWD
https://read.qxmd.com/read/38702842/early-goal-directed-management-after-out-of-hospital-cardiac-arrest-lessons-from-a-certified-cardiac-arrest-centre
#24
JOURNAL ARTICLE
Birgit Markus, Nikolaos Patsalis, Charlotte Müller, Georgios Chatzis, Leona Möller, Rosita Rupa, Simon Viniol, Susanne Betz, Bernhard Schieffer, Julian Kreutz
BACKGROUND: Despite continuous advances in post-resuscitation management, outcome after out-of-hospital cardiac arrest (OHCA) is limited. To improve the outcome, interdisciplinary Cardiac Arrest Centers (CACs) have been established in recent years, but survival remains low and treatment strategies vary considerably in clinical and geographical aspects. Here we analyzed a strategy of in-hospital post-resuscitation management while evaluating the outcome. METHODS: A broad spectrum of pre- and in-hospital parameters of 545 resuscitated patients, admitted to the Cardiac Arrest Center of the University Hospital of Marburg (MCAC) between 01/2018 and 12/2022 were retrospectively analyzed...
May 3, 2024: European Heart Journal. Quality of Care & Clinical Outcomes
https://read.qxmd.com/read/38702796/direct-metagenomics-investigation-of-non-surgical-hard-to-heal-wounds-a-review
#25
REVIEW
Madjid Morsli, Florian Salipante, Chloé Magnan, Catherine Dunyach-Remy, Albert Sotto, Jean-Philippe Lavigne
BACKGROUND: Non-surgical chronic wounds, including diabetes-related foot diseases (DRFD), pressure injuries (PIs) and venous leg ulcers (VLU), are common hard-to-heal wounds. Wound evolution partly depends on microbial colonisation or infection, which is often confused by clinicians, thereby hampering proper management. Current routine microbiology investigation of these wounds is based on in vitro culture, focusing only on a limited panel of the most frequently isolated bacteria, leaving a large part of the wound microbiome undocumented...
May 3, 2024: Annals of Clinical Microbiology and Antimicrobials
https://read.qxmd.com/read/38702164/the-relevance-of-naturopathy-as-a-therapeutic-tool-in-the-modern-era-a-narrative-review
#26
JOURNAL ARTICLE
Sumnalata Ma Dewangan, Braj Bhushan Kumar
BACKGROUND: There are numerous reports of remarkable recoveries from diseases through drugless healing systems. In an effort to enhance the understanding of naturopathic therapies, the author, a renowned BNYS doctor specializing in naturopathy, yoga, nutrition, and wellness, aims to explain the importance of drugless therapies in various disease conditions. OBJECTIVE: To provide a comprehensive overview of the relevance and efficacy of naturopathy as a therapeutic tool in modern healthcare...
May 3, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38701126/assessment-and-evaluation-of-work-related-musculoskeletal-disorders-among-nuclear-medicine-professionals-in-india-a-cross-sectional-study
#27
JOURNAL ARTICLE
Sam Blessing Viniston J, Shivanand Bhushan, Shovan Saha
BACKGROUND: Musculoskeletal disorders (MSDs) are a severe occupational health issue among medical radiation practitioners. It is mostly linked to personal protective wear, working posture, tools employed and ergonomics. OBJECTIVE: To assess and evaluate the musculoskeletal disorders among nuclear medicine professionals (NMP) in India. METHODS: An online survey was distributed to 455 NMP throughout India between November 2021 and March 2022 covering the demographic characteristics and questions for evaluation of musculoskeletal symptoms using the Standardized Nordic Musculoskeletal Questionnaire (NMQ)...
April 29, 2024: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/38699903/the-ethical-principles-in-ethical-guidance-documents-during-the-covid-19-pandemic-in-the-united-kingdom-and-the-republic-of-ireland-a-qualitative-systematic-review
#28
JOURNAL ARTICLE
Kesidha Raajakesary, Lucy Galvin, Kate Prendiville, Sarah Newport, Calum MacAnulty, Ghaiath Hussein
BACKGROUND: The sudden onset of the coronavirus disease 2019 (COVID-19) pandemic was accompanied by a myriad of ethical issues that prompted the issuing of various ethical guidance documents for health care professionals in clinical, research, and public health settings throughout the United Kingdom (UK) of Great Britain and Northern Ireland and the Republic of Ireland. The aim of this review was to identify the main principles in ethical guidance documents published in the UK and Ireland during the COVID-19 pandemic...
May 3, 2024: Prehospital and Disaster Medicine
https://read.qxmd.com/read/38698625/the-effect-of-hyperemesis-gravidarum-on-macular-thickness-corneal-thickness-and-intraocular-pressure-in-pregnancy
#29
JOURNAL ARTICLE
Erhan Okuyan, Ozlem Akgül, Zeki Baysal, Mehmet Serhat Mangan, Denizhan Bayramoglu, Lena Tureyici
AIM: Physiological changes in intraocular pressure as well as in the cornea and macula may occur during pregnancy. Therefore, we decided to investigate the effect of hyperemesis gravidarum on macular thickness, corneal thickness and intraocular pressure (IOP). MATERIAL AND METHODS: A total of 110 people, 55 of whom were diagnosed with hyperemesis gravidarum and 55 of whom were in the control group, were included in the study. The inclusion criteria for the study were as follows: first trimester (8-14 weeks of gestation) pregnancy with positive fetal heartbeat and no history of systemic disease, no continuous use of medication, diagnosis of hyperemesis gravidarum (ketonuria and weight loss of more than 3 kilograms or 5% of body weight), body mass index (BMI) within normal limits, age between 18 and 40, no alcohol use or smoking...
May 2, 2024: Zeitschrift Für Geburtshilfe und Neonatologie
https://read.qxmd.com/read/38693436/inclusion-body-myositis-viral-infections-and-tdp-43-a-narrative-review
#30
REVIEW
Vitalie Văcăraş, Romana Vulturar, Adina Chiş, Laura Damian
The ubiquitous RNA-processing molecule TDP-43 is involved in neuromuscular diseases such as inclusion body myositis, a late-onset acquired inflammatory myopathy. TDP-43 solubility and function are disrupted in certain viral infections. Certain viruses, high viremia, co-infections, reactivation of latent viruses, and post-acute expansion of cytotoxic T cells may all contribute to inclusion body myositis, mainly in an age-shaped immune landscape. The virally induced senescent, interferon gamma-producing cytotoxic CD8+ T cells with increased inflammatory, and cytotoxic features are involved in the occurrence of inclusion body myositis in most such cases, in a genetically predisposed host...
May 2, 2024: Clinical and Experimental Medicine
https://read.qxmd.com/read/38692978/adiposity-type-2-diabetes-and-atherosclerotic-cardiovascular-disease-risk-use-and-abuse-of-the-body-mass-index
#31
REVIEW
Benoit J Arsenault, André C Carpentier, Paul Poirier, Jean-Pierre Després
The worldwide prevalence of individuals with an elevated body weight has increased steadily over the past five decades. Billions of research dollars have been invested to improve our understanding of the causes and consequences of having an elevated body weight. All this knowledge has, however, failed to influence populational body weight trajectories of most countries around the world. Research on the definition of "obesity" has also evolved. Body mass index (BMI), the most commonly used tool to make its diagnosis, has major limitations...
April 14, 2024: Atherosclerosis
https://read.qxmd.com/read/38692716/sensorineural-hearing-loss-among-type-2-diabetic-patients-and-its-association-with-peripheral-neuropathy-a-cross-sectional-study-from-a-lower-middle-income-country
#32
JOURNAL ARTICLE
Saba Asghar, Zeeshan Ali, Ali Abdullah, Shabnam Naveed, Masroor Syed Ahmad, Tariq Syed Muhammad Rafi
INTRODUCTION: Despite potential links between diabetes and sensorineural hearing loss (SNHL), routine hearing assessments for diabetic patients are not standard practice. Our study aimed to investigate the prevalence of SNHL and its association with diabetes-related factors among patients with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS: This cross-sectional study was conducted at the Diabetes Clinic, Jinnah Postgraduate Medical Centre, Karachi, Pakistan, from May to September 2021...
May 1, 2024: BMJ Open
https://read.qxmd.com/read/38690215/left-bundle-branch-pacing-set-to-outshine-biventricular-pacing-for-cardiac-resynchronization-therapy
#33
EDITORIAL
Akash Batta, Juniali Hatwal
The deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacing-induced cardiomyopathy. Until recently, biventricular pacing (BiVP) was the only modality which could mitigate or prevent pacing induced dysfunction. Further, BiVP could resynchronize the baseline electromechanical dssynchrony in heart failure and improve outcomes. However, the high non-response rate of around 20%-30% remains a major limitation. This non-response has been largely attributable to the direct non-physiological stimulation of the left ventricular myocardium bypassing the conduction system...
April 26, 2024: World Journal of Cardiology
https://read.qxmd.com/read/38688828/evaluation-of-the-efficacy-and-safety-of-tenofovir-disoproxil-fumarate-in-intercepting-mother-to-child-transmission-of-hepatitis-b-virus
#34
RANDOMIZED CONTROLLED TRIAL
Dongxiang Han, Jianxiu Du, Wei Wang, Cui Wang
Vertical transmission of hepatitis B virus (HBV), especially in Asia, is a key target in the global elimination of HBV. This study assessed the effects of tenofovir disoproxil fumarate (TDF) in pregnant women for mother-to-infant transmission of HBV. A total of 122 pregnant women at our hospital met the inclusion criteria for high HBV DNA viral loads. They were randomly divided into TDF-treatment (n=70) and placebo (n=52) groups. Maternal liver function and serum HBV DNA load were tested before and after treatment...
April 2024: Acta Medica Okayama
https://read.qxmd.com/read/38688179/influence-of-glucagon-like-peptide-1-receptor-agonists-on-fat-accumulation-in-patients-with-diabetes-mellitus-and-non-alcoholic-fatty-liver-disease-or-obesity-a-systematic-review-and-meta-analysis-of-randomized-control-trials
#35
JOURNAL ARTICLE
Wanrun Xie, Zhenzhen Hong, Bo Li, Baoliang Huang, Shaobin Dong, Yuqi Cai, Lingyan Ruan, Qianhui Xu, Lunpan Mou, Yi Zhang
AIM: This systematic review and meta-analysis aimed to comprehensively evaluate the impact of glucagon-like peptide 1 receptor agonists (GLP-1RAs) on visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in individuals with diabetes mellitus and non-alcoholic fatty liver disease (NAFLD) or obesity. METHODS: A search of PubMed, Embase, and Web of Science until October 2023 identified 13 Randomized Controlled Trials (RCTs) meeting the inclusion criteria...
April 4, 2024: Journal of Diabetes and its Complications
https://read.qxmd.com/read/38684633/risk-of-adverse-cardiovascular-outcomes-in-postmenopausal-women-with-inflammatory-bowel-disease
#36
JOURNAL ARTICLE
Ruby Greywoode, Joseph Larson, Jellyana Peraza, Rachel Clark, Matthew A Allison, Naueen A Chaudhry, Peter F Schnatz, Aladdin H Shadyab, Robert B Wallace, Sylvia Wassertheil-Smoller
BACKGROUND: Individuals with inflammatory bowel disease (IBD) who lack traditional cardiovascular disease (CVD) risk factors, such as young females, are observed to experience adverse CVD outcomes. Whether women with IBD have increased CVD risk after the menopause transition is unclear. METHODS: We conducted a survival analysis of Women's Health Initiative (WHI) participants and excluded those with missing IBD diagnosis, model covariate data, follow-up data, or a baseline history of the following CVD outcomes: coronary heart disease (CHD), ischemic stroke, venous thromboembolism (VTE), peripheral arterial disease (PAD)...
April 29, 2024: Digestive Diseases and Sciences
https://read.qxmd.com/read/38680607/real-world-experience-of-posaconazole-therapeutic-drug-monitoring-in-oncology-patients-clinical-implications-of-hypoalbuminemia-as-a-predictor-of-subtherapeutic-posaconazole-levels
#37
JOURNAL ARTICLE
Guy Handley, John Greene, Anthony P Cannella, Ana Paula Velez, Shivan Shah, Yanina Pasikhova
BACKGROUND: Posaconazole maintains broad antifungal activity and is employed for prevention and treatment of invasive fungal infections in oncology patients. Older formulations required therapeutic drug monitoring, and specific plasma drug levels have been recommended. This study evaluated factors associated with subtherapeutic concentrations with the newer delayed-release tablet formulation. METHODS: In this retrospective, single-center cohort study at a national comprehensive cancer center, all oncology patients receiving delayed-release posaconazole at standard dosing of 300 mg orally per day from 06/2021 to 07/2023 with plasma drug concentration evaluation were identified...
May 2024: Open Forum Infectious Diseases
https://read.qxmd.com/read/38679338/navigating-biologic-therapies-in-elderly-asthma
#38
REVIEW
HyeIn Ji, Laren D Tan, George W Hafzalla, Nolan Nguyen, Abdullah Alismail
The prevalence of asthma among the elderly population has witnessed a notable rise, presenting unique challenges in diagnosis and management. Biologic therapies, such as omalizumab, mepolizumab, reslizumab, benralizumab, dupilumab, and tezepelumab, have demonstrated efficacy in targeting specific pathways associated with severe asthma in elderly individuals. However, a significant research gap exists in the application of these therapies in elderly asthma patients. Despite the considerable size of the elderly asthma population and the social and economic burden that this specific demographic imposes on society, the available body of research catering to this group is limited...
April 26, 2024: Respiratory Medicine
https://read.qxmd.com/read/38678974/the-impacts-of-dietary-inclusion-of-soybean-oil-and-linseed-oil-on-growth-performance-carcass-yield-and-health-status-of-growing-japanese-quail
#39
JOURNAL ARTICLE
Eman M Ahmed, Adel I Attia, Zenat A Ibrahem, Garsa Alshehry, Eman H Algarni, Nasser M Aldekhail, Mohamed E Abd El-Hack
Polyunsaturated fatty acids (PUFA), including n-6 and n-3 fatty acids, are essential for enhancing the performance and health of poultry. Avian species lack desaturase enzymes for endogenous synthesis of n-6 and n-3 fatty acids. This work aimed to determine the impacts of including soybean oil (SO) and linseed oil (LO) in quail diets on growth, lipid profile, hepatic and renal functions, immunity, and antioxidant status. A total of 350 Japanese quail chicks (1-wk-old) were randomly arranged into 7 dietary treatment groups...
April 6, 2024: Poultry Science
https://read.qxmd.com/read/38678762/european-clinical-practice-guidelines-for-the-definition-diagnosis-and-treatment-of-oligometastatic-esophagogastric-cancer-omec-4
#40
JOURNAL ARTICLE
Tiuri E Kroese, Sebastiaan Bronzwaer, Peter S N van Rossum, Sebastian F Schoppman, Pieter R A J Deseyne, Eric van Cutsem, Karin Haustermans, Philippe Nafteux, Melissa Thomas, Radka Obermannova, Hanna R Mortensen, Marianne Nordsmark, Per Pfeiffer, Anneli Elme, Antoine Adenis, Guillaume Piessen, Christiane J Bruns, Florian Lordick, Ines Gockel, Markus Moehler, Cihan Gani, Theodore Liakakos, John V Reynolds, Alessio G Morganti, Riccardo Rosati, Carlo Castoro, Francesco Cellini, Domenico D'Ugo, Franco Roviello, Maria Bencivenga, Giovanni de Manzoni, Mark I van Berge Henegouwen, Maarten C C M Hulshoff, Jolanda van Dieren, Marieke Vollebergh, Johanna W van Sandick, Paul Jeene, Christel Muijs, Marije Slingerland, Francine E M Voncken, Henk Hartgrink, Geert-Jan Creemers, Maurice J C van der Sangen, Grard A P Nieuwenhuijzen, Maaike Berbee, Marcel Verheij, Bas Wijnhoven, Laurens V Beerepoot, Nadia Haj Mohammad, Stella Mook, Jelle P Ruurda, Piotr Kolodziejczyk, Wojciech P Polkowski, Lucjan Wyrwicz, Maria Alsina, Josep Tabernero, Manuel Pera, Tania F Kanonnikoff, Andrés Cervantes, Magnus Nilsson, Stefan Monig, Anna D Wagner, Matthias Guckenberger, Ewen A Griffiths, Elizabeth Smyth, George B Hanna, Sheraz Markar, M Asif Chaudry, Maria A Hawkins, Edward Cheong, Hanneke W M van Laarhoven, Richard van Hillegersberg
INTRODUCTION: The OligoMetastatic Esophagogastric Cancer (OMEC) project aims to provide clinical practice guidelines for the definition, diagnosis, and treatment of esophagogastric oligometastatic disease (OMD). METHODS: Guidelines were developed according to AGREE II and GRADE principles. Guidelines were based on a systematic review (OMEC-1), clinical case discussions (OMEC-2), and a Delphi consensus study (OMEC-3) by 49 European expert centers for esophagogastric cancer...
April 16, 2024: European Journal of Cancer
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