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https://www.readbyqxmd.com/read/29454140/weight-management-in-rural-health-clinics-the-midwest-diet-and-exercise-trial
#1
Anna M Gorczyca, Richard A Washburn, Lauren Ptomey, Matthew S Mayo, Debra K Sullivan, Cheryl A Gibson, Robert Lee, Sarah Stolte, Joseph E Donnelly
Obesity prevalence is higher in rural compared to urban residents. Rural health clinics offer a potential venue for delivery of weight management. However, traditional programs require travel to attend on-site meetings which is impractical or inconvenient for rural residents. Clinic staff in most rural settings are unlikely to be trained to provide effective weight management. Remote delivery using group phone conferences (GP) or individual phone calls (IP), by staff associated with rural clinics eliminates the need for travel to attend on-site meetings...
February 14, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29454015/why-i-eat-at-night-a-qualitative-exploration-of-the-development-maintenance-and-consequences-of-night-eating-syndrome
#2
James A Shillito, James Lea, Stephanie Tierney, Jacqueline Cleator, Sara Tai, John P H Wilding
Night Eating Syndrome (NES), as a diagnosis, presents as a combination of disordered eating, sleep and mood. Patients identified as having both NES and obesity demonstrate poorer outcomes in terms of weight loss compared to those with NES only. However, research focusing on psychological factors associated with NES remains relatively underdeveloped. This study aimed to explore the relationship between NES and the experience of emotion from the perspective of patients accessing a weight management service. Ten adults who met diagnostic criteria for moderate or full NES took part in a semi-structured interview...
February 14, 2018: Appetite
https://www.readbyqxmd.com/read/29453728/single-site-port-robotic-assisted-hysterectomy-an-update
#3
REVIEW
Christos Iavazzo, Evelyn Eleni Minis, Ioannis D Gkegkes
Single-incision approach in robotic gynecology is a relatively new concept. The role of single-port systems in robotic hysterectomy, their advantages and disadvantages, as well as the technical challenges, are still under investigation. A systematic review was performed by searching in PubMed and Scopus databases. In 810 out of 1225 patients, hysterectomy was performed for non-neoplastic disease. Single-Site ® was the most common port system. Duration of the procedure and relative blood loss ranged from 60 to 311 min and 7 to 750 ml, respectively...
February 16, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29453590/attribution-of-weight-regain-to-emotional-reasons-amongst-european-adults-with-overweight-and-obesity-who-regained-weight-following-a-weight-loss-attempt
#4
Kirby Sainsbury, Elizabeth H Evans, Susanne Pedersen, Marta M Marques, Pedro J Teixeira, Liisa Lähteenmäki, R James Stubbs, Berit L Heitmann, Falko F Sniehotta
PURPOSE: Despite the wide availability of effective weight loss programmes, maintenance of weight loss remains challenging. Difficulties in emotion regulation are associated with binge eating and may represent one barrier to long-term intervention effectiveness in obesity. The purpose of this study was to determine the relationship between emotion regulation difficulties and the extent of weight regain in a sample of adults who had lost, and then regained, weight, and to examine the characteristics associated with emotional difficulties...
February 16, 2018: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29453465/screening-of-potential-adipokines-identifies-s100a4-as-a-marker-of-pernicious-adipose-tissue-and-insulin-resistance
#5
Peter Arner, Paul Petrus, David Esteve, Anne Boulomié, Erik Näslund, Anders Thorell, Hui Gao, Ingrid Dahlman, Mikael Rydén
BACKGROUND: Adipokines are peptides secreted from white adipose tissue (WAT), which have been linked to WAT dysfunction and metabolic complications of obesity. We set out to identify novel adipokines in subcutaneous WAT (sWAT) linked to insulin resistance (IR). METHODS: Gene expression was determined by microarray and qPCR in obese and non-obese subjects with varying degree of IR. WAT-secreted and circulating protein levels were measured by ELISA. RESULTS: In sWAT of 80 obese women discordant for IR, 44 genes encoding potential adipose-secreted proteins were differentially expressed...
January 30, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29453460/development-and-initial-characterization-of-a-novel-ghrelin-receptor-crispr-cas9-knockout-wistar-rat-model
#6
L J Zallar, B J Tunstall, C T Richie, Y J Zhang, Z B You, E L Gardner, M Heilig, J Pickel, G F Koob, L F Vendruscolo, B K Harvey, L Leggio
BACKGROUND/OBJECTIVES: Ghrelin, a stomach-derived hormone implicated in numerous behaviors including feeding, reward, stress, and addictive behaviors, acts by binding to the growth hormone secretagogue receptor (GHSR). Here, we present the development, verification, and initial characterization of a novel GHSR knockout (KO) Wistar rat model created with CRISPR genome editing. METHODS: Using CRISPR/Cas9, we developed a GHSR KO in a Wistar background. Loss of GHSR mRNA expression was histologically verified using RNAscope in wild-type (WT; n = 2) and KO (n = 2) rats...
January 30, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29452178/effects-of-canagliflozin-versus-glimepiride-on-adipokines-and-inflammatory-biomarkers-in-type-2-diabetes
#7
W Timothy Garvey, Luc Van Gaal, Lawrence A Leiter, Ujjwala Vijapurkar, James List, Robert Cuddihy, Jimmy Ren, Michael J Davies
OBJECTIVE: Type 2 diabetes and obesity are pro-inflammatory states associated with increased risk of cardiovascular disease. Canagliflozin, an SGLT2 inhibitor, demonstrated superiority in lowering HbA1c versus glimepiride with less hypoglycemia and greater weight reduction via loss of fat mass in a 52-week trial of type 2 diabetes patients. This post hoc, exploratory analysis assessed the effects of canagliflozin versus glimepiride on select adipokines, inflammatory biomarkers, and chemokines...
February 13, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29451645/intragastric-balloons-in-high-risk-obese-patients-in-a-brazilian-center-initial-experience
#8
Alana Costa Borges, Paulo César Almeida, Stella M T Furlani, Marcelo DE Sousa Cury, Shantanu Gaur
OBJECTIVE: to assess the short-term efficacy, tolerance and complications in high-risk morbidly obese patients treated with an intragastric balloon as a bridge for surgery. METHODS: we conducted a post-hoc analysis study in a Brazilian teaching hospital from 2010 to 2014, with 23 adult patients with a BMI of 48kg/m2, who received a single intragastric air or liquid balloon. We defined efficacy as 10% excess weight loss, and complications, as adverse events consequent to the intragastric balloon diagnosed after the initial accommodative period...
2018: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29451110/-risk-of-heart-failure-diminished-thanks-to-stomach-reduction-in-obesity
#9
B Botter, E Koolen, G van Montfort, F Bracke, A Bouwman, M Buise
BACKGROUND: Obesity is a chronic disease and a risk factor for heart failure. In end-stage heart failure, heart transplantation may be the only available treatment option, but obesity is a contraindication for this treatment because of its unfavourable prognosis. Bariatric surgery and its subsequent weight loss may affect the indication for transplantation in patients with heart failure and morbid obesity. CASE DESCRIPTION: A 46-year-old patient with morbid obesity and heart failure underwent gastric sleeve resection in preparation of a heart transplantation...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29451072/social-support-for-exercise-as-a-predictor-of-weight-and-physical-activity-status-among-puerto-rican-and-mexican-men-results-from-the-latino-men-s-health-initiative
#10
Meredith R Craven, Laurie Keefer, Alfred Rademaker, Amanda Dykema-Engblade, Lisa Sanchez-Johnsen
Social support is an important factor in increasing positive health outcomes and positive health behaviors across a variety of disease states including obesity. However, research examining the relationship between social support for exercise and weight and physical activity status, particularly among Latino men, is lacking. This paper examined whether social support for exercise predicted weight and physical activity status and whether the direction of these relationships differ as a function of Hispanic/Latino background (Puerto Rican/Mexican)...
February 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29450656/laparoscopic-subtotal-gastrectomy-in-morbid-obese-patients-a-valid-option-to-laparoscopic-gastric-bypass-in-particular-circumstances-prospective-study
#11
Italo Braghetto, Gustavo Martinez, Owen Korn, Marcelo Zamorano, Enrique Lanzarini, Enrique Narbona
BACKGROUND: Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) without resection of the distal stomach is largely performed over the world for morbid obesity. Potential risk of gastric remnant carcinoma development has been suggested. PURPOSE: To present the results obtained after LRYGB with resection of distal stomach. METHOD: This prospective study includes 400 consecutive patients. The mean body weight was 105.9 ± 16.8 Kg (range 83-145 kg), and body mass index (BMI) was 38...
February 15, 2018: Surgery Today
https://www.readbyqxmd.com/read/29449943/aging-like-physiological-changes-in-the-skin-of-japanese-obese-diabetic-patients
#12
Ai Ibuki, Shoko Kuriyama, Yukiko Toyosaki, Misaki Aiba, Moeko Hidaka, Yoshiko Horie, Chihiro Fujimoto, Fumiyuki Isami, Eriko Shibata, Yasuo Terauchi, Tomoko Akase
Objective: Obesity-associated diabetes causes aging-like changes to skin physiology in animal models, but there have been no clinical studies focusing on human obese diabetic patients. The purpose of this study was to examine the hypothesis that obesity-associated diabetes accelerates aging-like skin changes in Japanese people. Methods: This cross-sectional study enrolled obese-diabetes patients (body mass index ≥ 25 kg m-2) and healthy volunteers (body mass index < 25 kg m -2 ) as controls...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29447347/cultural-adaptation-of-an-evidence-based-lifestyle-intervention-for-diabetes-prevention-in-chinese-women-at-risk-for-diabetes-results-of-a-randomized-trial
#13
Zenong Yin, Judith Perry, Xiaoqin Duan, Meizi He, Ryan Johnson, Yanling Feng, Mark Strand
Background: The prevalence of both obesity and type 2 diabetes has been on the rise in China. This randomized controlled trial was conducted to test the feasibility and effectiveness of an evidence-based diabetes prevention program in Yuci, Shanxi Province, China from 2012 to 2014. Methods: Women with pre-diabetes, ages 25-65 y, were assigned randomly to a comparison (n=75) or 6-mo lifestyle intervention condition (n=109). Weight, fasting glucose, hemoglobin A1c and self-reported diet and physical activity were measured at baseline, 6 mo and 12 mo...
February 13, 2018: International Health
https://www.readbyqxmd.com/read/29446541/group-based-diet-and-physical-activity-weight-loss-interventions-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#14
Aleksandra J Borek, Charles Abraham, Colin J Greaves, Mark Tarrant
BACKGROUND: Many weight-loss interventions are delivered in groups but evidence on their effectiveness, and characteristics associated with effectiveness, is limited. We synthesised evidence on (1) design and delivery of group-based weight-loss interventions; (2) effectiveness; and (3) associations between intervention characteristics, change techniques, and effectiveness. METHODS: Five online databases were searched to May 2017 for randomised controlled trials (RCTs) of group-based diet and/or physical activity interventions for overweight/obese adults (BMI ≥ 25)...
February 15, 2018: Applied Psychology. Health and Well-being
https://www.readbyqxmd.com/read/29446036/mindfulness-approaches-and-weight-loss-weight-maintenance-and-weight-regain
#15
REVIEW
Carolyn Dunn, Megan Haubenreiser, Madison Johnson, Kelly Nordby, Surabhi Aggarwal, Sarah Myer, Cathy Thomas
PURPOSE OF REVIEW: There is an urgent need for effective weight management techniques, as more than one third of US adults are overweight or obese. Recommendations for weight loss include a combination of reducing caloric intake, increasing physical activity, and behavior modification. Behavior modification includes mindful eating or eating with awareness. The purpose of this review was to summarize the literature and examine the impact of mindful eating on weight management. RECENT FINDINGS: The practice of mindful eating has been applied to the reduction of food cravings, portion control, body mass index, and body weight...
February 14, 2018: Current Obesity Reports
https://www.readbyqxmd.com/read/29445118/n-1-methylnicotinamide-is-a-signalling-molecule-produced-in-skeletal-muscle-coordinating-energy-metabolism
#16
Kristoffer Ström, David Morales-Alamo, Filip Ottosson, Anna Edlund, Line Hjort, Sine W Jörgensen, Peter Almgren, Yuedan Zhou, Marcos Martin-Rincon, Carl Ekman, Alberto Pérez-López, Ola Ekström, Ismael Perez-Suarez, Markus Mattiasson, Pedro de Pablos-Velasco, Nikolay Oskolkov, Emma Ahlqvist, Nils Wierup, Lena Eliasson, Allan Vaag, Leif Groop, Karin G Stenkula, Céline Fernandez, Jose A L Calbet, Hans-Christer Holmberg, Ola Hansson
Obesity is a major health problem, and although caloric restriction and exercise are successful strategies to lose adipose tissue in obese individuals, a simultaneous decrease in skeletal muscle mass, negatively effects metabolism and muscle function. To deeper understand molecular events occurring in muscle during weight-loss, we measured the expressional change in human skeletal muscle following a combination of severe caloric restriction and exercise over 4 days in 15 Swedish men. Key metabolic genes were regulated after the intervention, indicating a shift from carbohydrate to fat metabolism...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29443598/evaluation-of-natural-product-compositions-for-appetite-suppression
#17
Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Tae-Woo Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia
A change in homeostasis between food intake and energy expenditure is the hallmark of obesity. Many plant-based weight-management products are available in dietary supplement markets with no direct efficacy comparison. In this in vivo acute feed intake study in rats, the appetite suppression efficacy of well-known natural ingredients in the weight-loss market were evaluated. We tested pure caffeine, potato skin extract, Cissus quadrangularis extract, Garcinia cambogia extract, Crocus sativus extract, raspberry ketone isolated from Rubus idaeus, one commercial product (Appetrex), and one novel composition (UP601)...
February 14, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29443438/obesity-is-associated-with-incident-atrial-fibrillation-independent-of-gender-a-meta-analysis
#18
Zain Asad, Mubasher Abbas, Isma Javed, Panagiotis Korantzopoulos, Stavros Stavrakis
BACKGROUND: The prevalence of obesity is increasing among the general population. Obesity is associated with increased risk of several cardiovascular conditions, which in turn may increase the risk for atrial fibrillation (AF). We performed a meta-analysis of cohort studies that examined the effect of obesity on the incidence of AF. In addition, we examined the effect of obesity on the incidence of AF stratified by gender. METHODS AND RESULTS: We searched the MEDLINE and EMBASE databases for studies evaluating the effect of obesity on AF...
February 14, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29440419/epitope-specific-monoclonal-antibodies-to-fsh%C3%AE-increase-bone-mass
#19
Yaoting Ji, Peng Liu, Tony Yuen, Shozeb Haider, Jiahuan He, Raquel Romero, Hao Chen, Madison Bloch, Se-Min Kim, Daria Lizneva, Lubna Munshi, Chunxue Zhou, Ping Lu, Jameel Iqbal, Zhen Cheng, Maria I New, Aaron J Hsueh, Zhuan Bian, Clifford J Rosen, Li Sun, Mone Zaidi
Pituitary hormones have long been thought solely to regulate single targets. Challenging this paradigm, we discovered that both anterior and posterior pituitary hormones, including FSH, had other functions in physiology. We have shown that FSH regulates skeletal integrity, and, more recently, find that FSH inhibition reduces body fat and induces thermogenic adipose tissue. A polyclonal antibody raised against a short, receptor-binding epitope of FSHβ was found not only to rescue bone loss postovariectomy, but also to display marked antiobesity and probeiging actions...
February 12, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29439689/acceptability-of-financial-incentives-for-maintenance-of-weight-loss-in-mid-older-adults-a-mixed-methods-study
#20
Bronwyn McGill, Blythe J O'Hara, Anne C Grunseit, Adrian Bauman, Dale Osborne, Luke Lawler, Philayrath Phongsavan
BACKGROUND: Health insurers worldwide implement financial incentive schemes to encourage health-related behaviours, including to facilitate weight loss. The maintenance of weight loss is a public health challenge, and as non-communicable diseases become more prevalent with increasing age, mid-older adults could benefit from programs which motivate weight loss maintenance. However, little is understood about their perceptions of using financial incentives to maintain weight loss. METHODS: We used mixed methods to explore the attitudes and views of participants who had completed an Australian weight loss and lifestyle modification program offered to overweight and obese health insurance members with weight-related chronic diseases, about the acceptability and usefulness of different types of financial incentives to support weight loss maintenance...
February 13, 2018: BMC Public Health
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