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Yasuhiro Shibata, Sota Kurihara, Seiji Arai, Haruo Kato, Tomomi Suzuki, Yoshiyuki Miyazawa, Hidekazu Koike, Kazuto Ito, Tetsuya Nakamura, Kazuhiro Suzuki
OBJECTIVES: Microsurgical subinguinal varicocelectomy is one of the best treatment modalities for varicoceles related to male infertility and scrotal pain. However, the difficulty in identifying testicular arteries, which should be spared, is a limitation of this technique. To visualize and identify the testicular arteries in spermatic cord during the operation, we examined the efficacy of intraoperative indocyanine green angiography (ICGA), which is regularly used in microsurgical neurosurgery...
October 13, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
Wataru Matsumiya, Shigeru Honda, Keiko Otsuka, Akiko Miki, Takayuki Nagai, Hisanori Imai, Sentaro Kusuhara, Makoto Nakamura
PURPOSE: The purpose of the study was to evaluate the 1-year visual and anatomical outcomes of combination therapy with intravitreal aflibercept (IVA) and verteporfin photodynamic therapy (vPDT) for polypoidal choroidal vasculopathy (PCV), and to determine the predictors of a good visual outcome. METHODS: This was a prospective case-series study. Twenty eyes from 20 treatment-naïve PCV patients were treated with combination therapy with IVA and vPDT. Best-corrected visual acuity (BCVA) and morphological parameters including polypoidal lesions in indocyanine green angiography (ICGA) were evaluated over 12 months of follow-up...
September 30, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Aniruddha Agarwal, Alessandro Invernizzi, Neha Kumari, Ramandeep Singh
PURPOSE: Retinochoroidal anastamosis (RCA) is known to be associated with retinal angiomatous proliferans rather than idiopathic macular telangiectasia. The case report describes a rare association of bilateral RCA with type II idiopathic macular telangiectasia in an elderly woman. CASE REPORT: A 65-year-old female patient presented with decreased vision in both eyes to the ophthalmology clinic. She was diagnosed with bilateral large serous retinal pigment epithelial detachments (PED)...
October 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Alain Gaudric, Sarah Mrejen
PURPOSE: To determine what retinal layer is primarily involved in multiple evanescent white dot syndrome compared with acute posterior multifocal placoid pigment epitheliopathy using multimodal imaging including indocyanine green angiography. METHODS: Color fundus photographs and fluorescein angiography, ICGA and spectral domain optical coherence tomography images of two typical acute cases, one of acute posterior multifocal placoid pigment epitheliopathy and one of multiple evanescent white dot syndrome, were assessed and compared...
September 21, 2016: Retinal Cases & Brief Reports
Eduardo A Novais, Luiz Roisman, Paulo Ricardo Chaves de Oliveira, Ricardo N Louzada, Emily D Cole, Mark Lane, Marco Bonini Filho, André Romano, João Rafael de Oliveira Dias, Caio V Regatieri, David Chow, Rubens Belfort, Philip Rosenfeld, Nadia K Waheed, Daniela Ferrara, Jay S Duker
Fluorescein angiography (FA) and indocyanine green angiography (ICGA) have been the gold standard for the evaluation of retinal and choroidal vasculature in the last three decades and have revolutionized the diagnosis of retinal and choroidal vascular diseases. The advantage of these imaging modalities lies in their ability to document retinal and choroidal vasculature through the dynamic assessment of contrast transit over time in the intravascular and extravascular spaces. However, disadvantages include the absence of depth resolution, blurring of details by contrast leakage, and the inability to selectively evaluate different levels of the retinal and choroidal microvasculature...
September 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Joo Eun Lee, Jae Pil Shin, Hyun Woong Kim, Woohyok Chang, Yu Cheol Kim, Sang Joon Lee, In Young Chung, Ji Eun Lee
PURPOSE: To investigate fixed-dosing aflibercept for treating polypoidal choroidal vasculopathy (PCV). METHODS: This phase IV, prospective, single-arm, interventional case series was conducted in eight centers. Forty treatment-naïve PCV patients were administered three monthly doses of intravitreal aflibercept (2.0 mg) and an injection every 2 months thereafter. Best-corrected visual acuity (BCVA) and central subfield macular thickness (CSMT) were measured at each visit...
September 14, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Aniruddha Agarwal, Kanika Aggarwal, Ankit Deokar, Spoorti Krishna Reddy Mandadi, Simar Rajan Singh, Ramandeep Singh, Aman Sharma, Reema Bansal, Vishali Gupta
PURPOSE: To describe optical coherence tomography angiography (OCTA) features of lesions of tubercular multifocal serpiginoid choroiditis (TB MSC) that developed paradoxical worsening (PW). METHODS: In this prospective study, subjects with TB MSC who developed PW upon initiation of anti-tubercular therapy were included. Multimodal imaging was performed using OCTA, enhanced-depth imaging OCT, fluorescein angiography (FA), and indocyanine green angiography (ICGA)...
September 6, 2016: Ocular Immunology and Inflammation
Seongyong Jeong, Min Sagong
BACKGROUND/AIMS: To compare the short-term efficacy of intravitreal aflibercept treatment according to the subtypes of polypoidal choroidal vasculopathy (PCV) based on indocyanine green angiography (ICGA). METHODS: Twenty-nine patients (29 eyes) with treatment-naïve subfoveal PCV were consecutively enrolled in this institutional study. The subjects were classified into two subtypes (type 1, polypoidal choroidal neovascularisation (CNV), 16 eyes; and type 2, idiopathic PCV, 13 eyes) based on the presence or absence of both feeder and draining vessels on ICGA...
September 5, 2016: British Journal of Ophthalmology
Georges Azar, Benjamin Wolff, Martine Mauget-Faÿsse, Marco Rispoli, Maria-Cristina Savastano, Bruno Lumbroso
PURPOSE: To describe and interpret the features of pachychoroid neovasculopathy (PNV) using optical coherence tomography angiography (OCTA) technique. METHODS: This is an observational case series of patients who presented with PNV. Best-corrected visual acuity (BCVA), anterior segment examination, dilated funduscopic examination, infrared and autofluorescence fundus images and spectral-domain optical coherence tomography (SD-OCT; B-scan, 'en-face' and OCTA) were carried out for all patients...
September 6, 2016: Acta Ophthalmologica
Deborah B Martins, Gina Farias-Eisner, Rachel S Mandelbaum, Han Hoang, James P Bradley, Justine C Lee
Skin flap vascularity is a critical determinant of aesthetic results in autologous ear reconstruction. In this study, we investigate the use of intraoperative laser-assisted indocyanine green angiography (ICGA) as an adjunctive measure of skin flap vascularity in pediatric autologous ear reconstruction. Twenty-one consecutive pediatric patients undergoing first-stage autologous total ear reconstruction were retrospectively evaluated. The first 10 patients were treated traditionally (non-ICGA), and the latter 11 patients were evaluated with ICGA intraoperatively after implantation of the cartilage construct and administration of suction...
May 2016: Plastic and Reconstructive Surgery. Global Open
Laura Moyal, Olivia Zambrowski, Charles Thirkill, Caroline Bottin, Rocio Blanco, Corinne Haioun, Eric H Souied
PURPOSE: To report the case of a patient whose retinal disease was found to be associated with a diffuse large B-cell lymphoma found 30 years after the apparent successful treatment of a classical Hodgkin lymphoma. METHODS: Observational case report. RESULTS: The authors describe the case of a 69-year-old man referred to their Department because of progressive, bilateral vision loss over the last few months. Deterioration in color vision and intense photophobia were also present...
August 26, 2016: Retinal Cases & Brief Reports
Gregg T Kokame, Jessica G Shantha, Kelsi Hirai, Julia Ayabe
BACKGROUND AND OBJECTIVE: To evaluate the diagnostic capability of en face spectral-domain optical coherence tomography (SD-OCT) in patients with polypoidal choroidal vasculopathy (PCV) diagnosed by indocyanine green angiography (ICGA). PATIENTS AND METHODS: A retrospective, consecutive case series of 100 eyes diagnosed with PCV by ICGA were imaged with en face SD-OCT. Evaluation of the PCV complex on en face SD-OCT was performed on the ability to diagnose PCV by the characteristic configuration of the PCV complex and the extent and size of the PCV lesion...
August 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Ari Shinojima, Kyoko Fujita, Ryusaburo Mori, Akiyuki Kawamura, Mitsuko Yuzawa, Tsutomu Yasukawa
PURPOSE: To identify locations of hypofluorescent lesions on late-phase indocyanine green angiography (ICGA) in patients with central serous chorioretinopathy (CSC) using en-face optical coherence tomography (OCT). PROCEDURES: We retrospectively studied 25 consecutive untreated CSC patients, using swept-source OCT and ICGA. En-face swept-source OCT images were automatically segmented and flattened with Bruch's membrane (BrM). We compared the sizes of hyperreflective areas in the 25 CSC and 25 contralateral eyes on en-face images and hypofluorescent areas on ICGA after 30 min...
2016: Ophthalmologica. Journal International D'ophtalmologie
Rupesh Agrawal, Lilian Koh Hui Li, Vikram Nakhate, Neha Khandelwal, Padmamalini Mahendradas
PURPOSE: We assessed the application of the choroidal vascularity index (CVI) in the follow-up of Vogt-Koyanagi-Harada disease (VKH) patients derived from image binarization of enhanced depth imaging optical coherence tomography (EDI-OCT) images with Fiji software. Our secondary objective was to derive the retinochoroidal vascularity index based on en face fundus fluorescein and indocyanine green angiography (FFA and ICGA). METHODS: In this retrospective cohort study, EDI-OCT scans of 18 eyes of 9 patients with VKH were obtained at baseline within 2 weeks of acute presentation, and again at 6 to 12 months...
July 2016: Translational Vision Science & Technology
Ozlem Balci, Amel Gasc, Bruno Jeannin, Carl P Herbort
The purpose of this study is to investigate the performance, utility, and precision of enhanced depth imaging optical coherence tomography (EDI-OCT) versus indocyanine green angiography (ICGA) in tracking any fluctuation in the activity of stromal choroiditis in response to therapeutic interventions during long-term follow-up. Patients with a diagnosis of Vogt-Koyanagi-Harada (VKH) disease or birdshot retinochoroiditis (BRC), with untreated initial disease, and having had long-term follow-up, including both ICGA and EDI-OCT, were recruited at the Centre for Ophthalmic Specialised care, Lausanne, Switzerland...
August 2, 2016: International Ophthalmology
Min Wang, Yao Zhou, Simon S Gao, Wei Liu, Yongheng Huang, David Huang, Yali Jia
PURPOSE: We observed and analyzed the morphologic characteristics of polypoidal lesions and abnormal branching vascular network (BVN) in patients with polypoidal choroidal vasculopathy (PCV) by optical coherence tomography angiography (OCTA). METHODS: A retrospective observational case series was done of patients with PCV. All patients were scanned with a 70-kHz spectral-domain OCT system using the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm to distinguish blood flow from static tissue...
July 1, 2016: Investigative Ophthalmology & Visual Science
Marco Pellegrini, Alessandra Acquistapace, Marta Oldani, Matteo Giuseppe Cereda, Andrea Giani, Mariano Cozzi, Giovanni Staurenghi
PURPOSE: To assess the status of choriocapillaris in eyes with macular atrophy secondary to age-related macular degeneration (AMD) (geographic atrophy [GA]) and Stargardt disease (STGD) using optical coherence tomography angiography (OCTA). DESIGN: Prospective, observational case series. PARTICIPANTS: A total of 14 patients (20 eyes) affected by GA and 10 patients (20 eyes) affected by STGD. METHODS: Each patient underwent a complete ophthalmological examination including fundus autofluorescence (FAF), dynamic simultaneous fluorescein angiography (FA) and indocyanine green angiography (ICGA), enhanced-depth imaging optical coherence tomography (EDI-OCT) (HRA+OCT Spectralis, Heidelberg Engineering, Heidelberg, Germany), and OCTA using AngioVue technologies (Optovue Inc, Freemont, CA)...
September 2016: Ophthalmology
Kanika Aggarwal, Aniruddha Agarwal, Sarakshi Mahajan, Alessandro Invernizzi, Spoorti Krishna Reddy Mandadi, Ramandeep Singh, Reema Bansal, Mangat R Dogra, Vishali Gupta
PURPOSE: To report the imaging characteristics of acute Vogt-Koyanagi-Harada (VKH) disease using optical coherence tomography angiography (OCTA). METHODS: In this prospective study, patients with acute VKH (n = 10; mean age: 30.5 ± 13.43 years) underwent multimodal imaging (baseline and follow-up) using fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICGA), OCT, and OCTA. The OCTA images were analyzed to assess the retinochoroidal vasculature and compared with other imaging techniques...
July 20, 2016: Ocular Immunology and Inflammation
Yao Wang, Zhi-Qing Chen, Wei Wang, Xiao-Yun Fang
Purpose. To investigate the prevalence and characteristics of focal choroidal excavation (FCE) concurrent with central serous chorioretinopathy (CSC) using multimodal imaging. Methods. This was a retrospective single-institution study. Clinical features and multimodal imaging findings were analyzed in eyes with CSC and FCEs, using imaging methods including optical coherence tomography (OCT), OCT angiography (OCTA), fluorescein angiography (FA), indocyanine green angiography (ICGA), fundus autofluorescence (FAF), and multispectral imaging...
2016: Journal of Ophthalmology
Cheng-Kuo Cheng, Chun-Kai Chang, Chi-Hsien Peng
PURPOSE: To compare the efficacy and the detrimental effects of half-drug dose and half-laser light fluence of photodynamic therapy (PDT) for the treatment of chronic central serous chorioretinopathy. DESIGN: We conducted a prospective randomized, observer-masked comparison study. METHODS: Forty eyes (40 patients) with chronic central serous chorioretinopathy were enrolled in this study and were equally divided into 2 groups. The first (half-dose) group received only half the standard dose of verteporfin infusion (3 mg/m) and were irradiated by the standard 83 seconds of laser light (50 J/cm) for the PDT treatment; the second (half-fluence) group received the standard dose of verteporfin infusion (6 mg/m) and were irradiated by only 42 seconds of laser light (25 J/cm)...
July 14, 2016: Retina
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