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https://www.readbyqxmd.com/read/29625447/imaging-of-corneal-neovascularization-optical-coherence-tomography-angiography-and-fluorescence-angiography
#1
Matthias Brunner, Vito Romano, Bernhard Steger, Riccardo Vinciguerra, Samuel Lawman, Bryan Williams, Nicholas Hicks, Gabriela Czanner, Yalin Zheng, Colin E Willoughby, Stephen B Kaye
Purpose: The purpose of this study was to compare optical coherence tomography angiography (OCTA) and indocyanine green angiography (ICGA) for the assessment of corneal neovascularization (CoNV). Methods: Patients with CoNV extending at least 3 mm into the cornea were included. All patients underwent corneal imaging at the same visit. Images were recorded using the AngioVue OCTA system (Optovue, Inc.) with the long corneal adaptor module (CAM-L). ICGA images were recorded with fluorescent filters using the Heidelberg system (HRA2 Scanning Laser Ophthalmoscope; Heidelberg Engineering)...
March 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29625446/quantitative-evaluation-of-vascular-microcirculation-using-contrast-enhanced-ultrasound-imaging-in-rabbit-models-of-choroidal-melanoma
#2
Min Gao, Jinhua Tang, Kun Liu, Ming Yang, Haiyun Liu
Purpose: We investigated the application of contrast-enhanced ultrasound (CEUS) to quantify vascular perfusion in two animal models of choroidal melanoma. Methods: B16F10 and choroidal melanoma cell line (OCM1) melanoma xenografts were implanted into the cyclodialysis cleft of rabbits' right eyes. Fundus photography, indocyanine green angiography (ICGA), B-mode ultrasound, and CEUS were used to examine the tumors. Standard vascular parameters of CEUS imaging were evaluated, including the area under the receiver operating characteristic curve (AUC), peak intensity (IMAX), mean transit time (mTT), rise time, and time to peak...
March 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29603787/intraoperative-use-of-indocyanine-green-angiography-for-selecting-the-more-reliable-perforator-of-the-anterolateral-thigh-flap-a-comparison-study
#3
Simone La Padula, Barbara Hersant, Jean Paul Meningaud
INTRODUCTION: Anatomical variability of anterolateral thigh flap (ALT) perforators has been reported. The aim of this study is to assess if the use of intraoperative indocyanine green angiography (iICGA) can help surgeons to choose the ALT flap best perforator to be preserved. PATIENTS AND METHODS: A retrospective study was conducted in 28 patients with open tibial fracture, following a road traffic crash, who had undergone ALT flap. Patients were classified into two groups: ICGA group (iICGA was used to select the more reliable perforator) and control group...
March 30, 2018: Microsurgery
https://www.readbyqxmd.com/read/29600987/the-use-of-optical-coherence-tomography-angiography-for-detecting-choroidal-neovascularization-compared-to-standard-multimodal-imaging
#4
T Soomro, J Talks
PurposeTo assess OCT angiography (OCTA) effectiveness at detecting choroidal neovascularization (CNV) in cases of suspected neovascular age related macular degeneration (nAMD), chronic central serous retinopathy (cCSR) and pathological myopia compared to FFA and how it compares to a multimodal approach (OCT, FFA and ICGA) for detecting the vascular network.MethodsThis was a retrospective observational cohort study of patients who had clinical and/or OCT findings suggestive of CNV, having further investigation with FFA, with or without ICG, and had same day OCTA using the Heidelberg Spectralis OCT2 beta angiography module...
March 30, 2018: Eye
https://www.readbyqxmd.com/read/29577101/management-of-recalcitrant-polypoidal-choroidal-vasculopathy-by-feeder-vessel-laser-photocoagulation
#5
Jay Sheth, Giridhar Anantharaman, Shruti Chandra, Mahesh Gopalakrishnan
Purpose: To describe management of residual branch vascular network (BVN) in polypoidal choroidal vasculopathy (PCV) by thermal laser photocoagulation of feeder vessel. Observations: Case report of sixty-four year old female with polypoidal choroidal vaculopathy (PCV) with moderate response to seven doses of intravitreal ranibizumab, six doses of intravitreal bevacizumab and one session of photodynamic therapy (PDT). The patient has resolved polyps but persistence of disease activity due to residual BVN and large pigment epithelial detachment (PED)...
March 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29566395/angiographic-and-tomographic-prognostic-factors-of-chronic-central-serous-chorioretinopathy-treated-with-half-dose-photodynamic-therapy
#6
Chung Yee Chung, Yee Yan Chan, Kenneth K W Li
AIMS: To identify the angiographic and tomographic prognostic factors of chronic central serous chorioretinopathy (CSC) treated with half-dose photodynamic therapy (PDT). METHODS: This is a consecutive series of 61 eyes with chronic CSC treated with half-dose PDT from January 1, 2009 to October 31, 2016. RESULTS: The mean logMAR best-corrected visual acuity (BCVA) improved from 0.47 to 0.31 at 3 months (p < 0.001). From multivariate regression, the final BCVA was significantly associated with the baseline BCVA (p = 0...
March 22, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29554076/instrumental-difference-in-assessing-choroidal-hyperpermeability-and-photodynamic-therapy-in-chronic-central-serous-chorioretinopathy
#7
Seung Min Lee, Han Jo Kwon, Sung Who Park, Ji Eun Lee, Ik Soo Byon
PURPOSE: To investigate the difference in choroidal hyperpermeability (CH) assessed using digital fundus camera (DFC) and scanning laser ophthalmoscope (SLO) and its effect on photodynamic therapy (PDT) outcomes in chronic central serous chorioretinopathy. METHODS: Midphase indocyanine green angiography (ICGA) images were acquired using both DFC and SLO in 38 consecutive eyes with chronic central serous chorioretinopathy in this retrospective study. Scanning laser ophthalmoscope-ICGA was taken immediately after DFC-ICGA...
March 16, 2018: Retina
https://www.readbyqxmd.com/read/29436399/type-2-choroidal-neovascularisation-in-polypoidal-choroidal-vasculopathy-a-retrospective-case-series
#8
Shuting Liang, Xuan Shi, Philip J Rosenfeld, Xiaoxin Li
BACKGROUND AND OBJECTIVE: To demonstrate the coexistence of polypoidal choroidal vasculopathy (PCV) with type 2 neovascularisation (NV), we used multimodal imaging, including spectral-domain optical coherence tomography angiography (SD-OCTA), to identify both types of lesions in the same eye. STUDY DESIGN: This retrospective case series reviewed patients with PCV diagnosed with indocyanine green angiography (ICGA), fluorescein angiography (FA), SD-OCT and SD-OCTA...
February 7, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29435588/everest-report-5-clinical-outcomes-and-treatment-response-of-polypoidal-choroidal-vasculopathy-subtypes-in-a-multicenter-randomized-controlled-trial
#9
Colin S Tan, Louis W Lim, Wei Kiong Ngo, Tock Han Lim
Purpose: The purpose of this study was to describe the characteristics of polypoidal choroidal vasculopathy (PCV) subtypes among patients from a multicenter randomized controlled trial and to determine the impact of PCV subtypes on clinical outcomes. Methods: This was a prospective cohort study of 61 patients with macular PCV from the EVEREST study. Indocyanine green (ICGA) and fluorescein angiography (FA) obtained using standardized imaging protocols were graded to classify PCV into three subtypes...
February 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29428319/characterization-and-functional-correlation-of-multiple-imaging-modalities-with-focal-choroidal-excavation
#10
Yun-Chen Chen, Yu-Bai Chou, Cheng-Kuan Lin, Chia-Chen Tsai, Tsui-Kang Hsu, Yu-Fan Chang, Hsiao-Ming Chao, Tao-Hsin Tung, Shih-Jen Chen, Jorn-Hon Liu
BACKGROUND: To investigate the clinical manifestations and imaging features of near-infrared autofluorescence (NIA), infrared reflectance (IR), fundus autofluorescence (FAF), indocyanine green angiography (ICGA) and fluorescein angiography (FAG) in the detection of patients with focal choroidal excavation (FCE) identified by cross-sectional spectral-domain optical coherence tomography (SD-OCT). METHODS: This retrospective cross-sectional study included 12 eyes of 10 Taiwanese patients with FCE diagnosed by SD-OCT...
February 7, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29424884/clinical-research-on-one-third-dose-verteporfin-photodynamic-therapy-in-the-treatment-of-chronic-central-serous-chorioretinopathy
#11
L Hua, B Lin, J Hong, H-B Min, W-L Han, T-Y Zhou, Z-Q Zhang
OBJECTIVE: To observe the curative effect and safety of one-third dose Verteporfin photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC). PATIENTS AND METHODS: A total of 60 patients (68 eyes) treated in our hospital from January 2016 to December 2016 were selected in this study, and they were diagnosed with chronic CSC via fluorescein fundus angiography (FFA), indocyanine green angiography (ICGA) and optical coherence tomography (OCT)...
January 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29409857/early-choriocapillaris-changes-after-half-fluence-photodynamic-therapy-in-chronic-central-serous-chorioretinopathy-evaluated-by-optical-coherence-tomography-angiography-preliminary-results
#12
Ali Demircan, Ceren Yesilkaya, Zeynep Alkin
BACKGROUND: The purpose of this study is to examine the choridal perfusion in patients with chronic central serous chorioretinopathy (CSC) after half-fluence photodynamic therapy (PDT) in the early post-treatment period. METHODS: This retrospective study included patients with chronic CSC. Indocyanine green angiography (ICGA) guided half-fluence PDT was applied to the all eyes. Best corrected visual acuity (BCVA) was assessed by Snellen chart and central retinal thickness (CRT) and subfoveal choroidal thickness (SFCT) was measured by spectral domain optical coherence tomography (SD-OCT) before PDT and at 3 and 30 days following the therapy...
February 1, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29392641/optical-coherence-tomography-angiography-findings-of-an-optic-disc-melanocytoma-in-a-glaucoma-eye
#13
Yoshiyuki Kita, Gábor Hollό, Akiko Murai, Ritsuko Kita, Akito Hirakata
PURPOSE: To determine the optical coherence tomography angiography (OCTA) characteristics of a case of optic disc melanocytoma (ODM) associated with glaucomatous visual field and retinal nerve fiber layer (RNFL) defects in normal tension glaucoma. METHODS: The left eye of a 37-year-old female patient followed for a stable ODM for 10 years was investigated with OCT, OCTA, fluorescein (FA), and indocyanine green (ICGA) angiography. The ODM was unchanged, but a previously unknown inferotemporal neuroretinal rim loss and inferotemporal and superotemporal wedge shape glaucomatous RNFL thinning were seen with corresponding glaucomatous visual field defects...
February 1, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29313555/correlation-of-values-for-indocyanine-green-angiography-in-the-arterographically-normal-lower-extremity
#14
Paul J Kim, Christopher E Attinger, Cameron M Akbari, Caitlin Ward
INTRODUCTION: Indocyanine green angiography (ICGA) is an assessment tool used to detect the degree of perfusion of tissue. This technology is being utilized in a variety of applications, including in the lower extremity. Principally, ICGA has been reported as a tool to determine pre-, intra-, or post-operative perfusion. The aim of this study is to determine objective values for ICGA in patients with arterographically normal lower extremities. MATERIALS AND METHODS: Prospectively, 20 patients were identified with no history of peripheral vascular disease who were scheduled to undergo distal subtraction angiography of the lower extremity...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29303152/response-of-central-serous-chorioretinopathy-evaluated-by-multimodal-retinal-imaging
#15
R Sacconi, G Baldin, A Carnevali, L Querques, A Rabiolo, G Marchini, F Bandello, G Querques
PurposeTo identify predictive biomarkers of treatment outcomes by multimodal retinal imaging in patients affected by central serous chorioretinopathy (CSC).Patients and methodsIn this interventional non-randomized clinical study, 27 treatment-naive CSC patients were prospectively enrolled and treated with oral eplerenone for 5-13 weeks. Primary outcomes included presence of pathological findings on indocyaine green angiography (ICGA), structural optical coherence tomography (OCT) and OCT-angiography (OCT-A) at baseline associated with different response to the treatment...
January 5, 2018: Eye
https://www.readbyqxmd.com/read/29276655/polypoidal-choroidal-vasculopathy
#16
Joon-Bom Kim, Rajinder S Nirwan, Ajay E Kuriyan
Purpose of Review: The goal of this paper is to review the recent literature of polypoidal choroidal vasculopathy (PCV) and provide an update on the epidemiology, pathophysiology, clinical findings, and management. Recent Findings: Although indocyanine-green angiography (ICGA) is still the gold standard for diagnosis of PCV, the use of en face optical coherence tomography (OCT) and OCT angiography are useful tools in the diagnosis of PCV. Studies demonstrate superior treatment outcomes with combination photodynamic therapy (PDT) and anti-vascular endothelial growth factor (VEGF) therapy...
June 2017: Current Ophthalmology Reports
https://www.readbyqxmd.com/read/29258731/characteristics-and-visual-outcome-of-refractory-retinal-vasculitis-associated-with-antineutrophil-cytoplasm-antibody-associated-vasculitides
#17
Miaoli Lin, Stephen D Anesi, Lina Ma, Aseef Ahmed, Karen Small, C Stephen Foster
PURPOSE: To describe the clinical characteristics, therapies, visual outcomes, and prognoses of patients with retinal vasculitis associated with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV). DESIGN: Retrospective case series. METHODS: Patients diagnosed with retinal vasculitis associated with AAV and at least 6 months of follow-up were included. Demographic data, systemic and ocular features, best-corrected visual acuity at the initial visit and latest visit, fluorescein angiography (FA) and indocyanine green angiography (ICGA) findings, therapy regimen, and outcome were collected from the Massachusetts Eye Research and Surgery Institution (MERSI) database from 2006 to 2017...
March 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29232336/comparison-among-different-diagnostic-methods-in-the-study-of-type-and-activity-of-choroidal-neovascular-membranes-in-age-related-macular-degeneration
#18
Vittoria Ravera, Andrea Giani, Marco Pellegrini, Marta Oldani, Alessandro Invernizzi, Elisa Carini, Mario Cigada, Ferdinando Bottoni, Giovanni Staurenghi
PURPOSE: To determine interobserver and intraobserver agreement in classifying the subtypes of choroidal neovascularization (CNV) and the decision of retreatment in patients affected by exudative age-related macular degeneration. Different imaging techniques were evaluated individually and compared with multiimaging. METHODS: Fifty-two patients with naive CNV in age-related macular degeneration were evaluated after 3 monthly intravitreal injections of ranibizumab...
December 8, 2017: Retina
https://www.readbyqxmd.com/read/29227980/spectral-domain-optical-coherence-tomography-angiography-for-the-diagnosis-and-evaluation-of-polypoidal-choroidal-vasculopathy
#19
Talisa E de Carlo, Gregg T Kokame, Jessica G Shantha, James C Lai, Raymond Wee
PURPOSE: To compare the diagnostic ability of optical coherence tomography angiography (OCTA) with indocyanine green angiography (ICGA) in polypoidal choroidal vasculopathy (PCV). METHODS: Retrospective review of 47 eyes with PCV imaged with ICGA and OCTA. For each eye, it was determined which imaging modality better delineated the PCV complex. The presence of a branching vascular network (BVN) and polyp(s) were noted. RESULTS: PCV was better visualized with ICGA in 21 eyes (44...
2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29200818/photodynamic-therapy-combined-with-antivascular-endothelial-growth-factor-treatment-for-recalcitrant-chronic-central-serous-chorioretinopathy
#20
Masumi G Asahi, Andrew T Chon, Esmeralda Gallemore, Ron P Gallemore
Purpose: To determine whether combination photodynamic therapy (PDT) and antivascular endothelial growth factor (VEGF) therapy is effective in the management of chronic central serous chorioretinopathy (CSC) recalcitrant to conventional therapy. Methods: This was a retrospective analysis of eight patients with chronic CSC unresponsive to topical nonsteroidal anti-inflammatory drugs, focal photocoagulation, anti-VEGF alone, or PDT alone. All patients were evaluated with a full ophthalmic examination, spectral-domain optical coherence tomography (OCT), fluorescein angiography (FA), and most with indocyanine green angiography (ICGA) followed by treatment with half-fluence PDT and intravitreal anti-VEGF injection (seven bevacizumab, one aflibercept)...
2017: Clinical Ophthalmology
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