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https://www.readbyqxmd.com/read/29333859/chromatographic-separation-and-visual-detection-on-wicking-microfluidic-devices-quantitation-of-cu2-in-surface-ground-and-drinking-water
#1
Gayan C Bandara, Christopher Heist, Vincent T Remcho
Copper is widely applied in industrial and technological applications, and is an essential micro nutrient for humans and animals. However, exposure to high environmental levels of copper, especially through drinking water, can lead to copper toxicity, resulting in severe acute and chronic health effects. Therefore, regular monitoring of aqueous copper ions has become necessary as recent anthropogenic activities have led to elevated environmental concentrations of copper. On-site monitoring processes require an inexpensive, simple, and portable analytical approach capable of generating reliable qualitative and quantitative data efficiently...
January 15, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29333102/an-amino-acids-mixture-attenuates-glycemic-impairment-but-not-affects-adiposity-development-in-rats-fed-with-ages-containing-diet
#2
Yi-Hung Liao, Chung-Yu Chen, Chiao-Nan Chen, Chia-Ying Wu, Shiow-Chwen Tsai
Background: Unhealthy western dietary patterns lead to over-consumption of fat and advanced glycation end-products (AGEs), and these account for the developments of obesity, diabetes, and related metabolic disorders. Certain amino acids (AAs) have been recently demonstrated to improve glycemia and reduce adiposity. Therefore, our primary aims were to examine whether feeding an isoleucine-enriched AA mixture (4.5% AAs; Ile: 3.0%, Leu: 1.0%, Val: 0.2%, Arg: 0.3% in the drinking water) would affect adiposity development and prevent the impairments of glycemic control in rats fed with the fat/AGE-containing diet (FAD)...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29332745/a-critical-overview-of-the-current-myofascial-pain-literature-january-2018
#3
REVIEW
Jan Dommerholt, Todd Hooks, Li-Wei Chou, Michelle Finnegan
The majority of papers included in the quarterly review discuss various aspects of dry needling (DN), which continues to be of interest to researchers and clinicians. A study by Liu et al. is the first paper to examine the effects of DN of acetylcholine, esterase and receptors. The study provides support for the integrated trigger point hypothesis and for DN. A paper by Hightower and colleagues found an intriguing link between low magnesium levels in the drink water supply, vitamin D, and myofascial pain, cancer, tendon ruptures, and colon polyps...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332196/bioelectronic-modulation-of-carotid-sinus-nerve-activity-in-the-rat-a-potential-therapeutic-approach-for-type-2-diabetes
#4
Joana F Sacramento, Daniel J Chew, Bernardete F Melo, Matteo Donegá, Wesley Dopson, Maria P Guarino, Alison Robinson, Jesus Prieto-Lloret, Sonal Patel, Bradley J Holinski, Nishan Ramnarain, Victor Pikov, Kristoffer Famm, Silvia V Conde
AIMS/HYPOTHESIS: A new class of treatments termed bioelectronic medicines are now emerging that aim to target individual nerve fibres or specific brain circuits in pathological conditions to repair lost function and reinstate a healthy balance. Carotid sinus nerve (CSN) denervation has been shown to improve glucose homeostasis in insulin-resistant and glucose-intolerant rats; however, these positive effects from surgery appear to diminish over time and are heavily caveated by the severe adverse effects associated with permanent loss of chemosensory function...
January 14, 2018: Diabetologia
https://www.readbyqxmd.com/read/29331934/characterization-and-release-profile-of-mn-al-bearing-deposits-in-drinking-water-distribution-systems
#5
Guiwei Li, Yuanxun Ding, Hongfu Xu, Junwei Jin, Baoyou Shi
Inorganic contaminants accumulation in drinking water distribution systems (DWDS) is a great threat to water quality and safety. This work assessed the main risk factors for different water pipes and discovered the release profile of accumulated materials in a full scale distribution system frequently suffered from water discoloration problem. Physicochemical characterization of pipe deposits were performed using X-ray fluorescence, scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy...
January 9, 2018: Chemosphere
https://www.readbyqxmd.com/read/29331907/applying-ultraviolet-persulfate-uv-ps-pre-oxidation-for-controlling-ultrafiltration-membrane-fouling-by-natural-organic-matter-nom-in-surface-water
#6
Jiayu Tian, Cuiwei Wu, Huarong Yu, Shanshan Gao, Guibai Li, Fuyi Cui, Fangshu Qu
Membrane fouling is a recognized obstacle for the application of ultrafiltration (UF) for drinking water treatment. In this study, ultraviolet/persulfate (UV/PS) oxidation was employed as a pretreatment to control membrane fouling caused by natural organic matter (NOM) in surface water. The effects of UV/PS pretreatment on amounts and characteristics of NOM were investigated in terms of dissolved organic carbon, fluorescent spectrum, molecular weight distribution and hydrophobicity. UF membrane fouling during filtration of raw and pre-oxidized water was compared with transmembrane pressure development, and the fouled membranes were further characterized using scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR)...
January 5, 2018: Water Research
https://www.readbyqxmd.com/read/29331810/behavior-of-cylindrospermopsis-raciborskii-during-coagulation-and-sludge-storage-higher-potential-risk-of-toxin-release-than-microcystis-aeruginosa
#7
Hongmin Li, Haiyan Pei, Hangzhou Xu, Yan Jin, Jiongming Sun
Owing to the global warming and its strong adaptability, Cylindrospermopsis raciborskii has spread world-wide. However, as one of toxic cyanobacteria in many drinking water sources, it has not been drawn proper consideration in drinking water treatment plants so far. The investigation aimed at unveiling the fate of C. raciborskii during polyaluminum ferric chloride (PAFC) coagulation and sludge storage, revealing its differences from Microcystis aeruginosa. Results showed that C. raciborskii cells were effectively removed intactly under optimum coagulation conditions, but PAFC at higher dosages (>10 mg/L) triggered additional cylindrospermopsins release...
January 5, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29331766/roflumilast-type-4-phosphodiesterase-inhibitor-attenuates-inflammation-in-rats-with-ulcerative-colitis-via-down-regulation-of-inos-and-elevation-of-camp
#8
Nahla E El-Ashmawy, Naglaa F Khedr, Hoda A El-Bahrawy, Samar A El-Adawy
BACKGROUND: Roflumilast (Rof), a phosphodiesterase 4 (PDE4) inhibitor, has been shown to be an effective agent in inflammatory diseases and marketed for chronic obstructive pulmonary disease. OBJECTIVE: This study was conducted to examine the potential anti-inflammatory effects of Rof in dextran sulphate sodium (DSS)-induced ulcerative colitis (UC) in rats and to investigate the molecular mechanisms underlying these effects. METHODS: Forty male Wistar rats were divided into four groups: normal control, colitis group (rats received 5% DSS in their drinking water continuously for 7 days), Rof group, and sulfasalazine (SLZ) group...
January 10, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29331639/identification-of-the-disinfection-byproducts-of-bisphenol-s-and-the-disrupting-effect-on-peroxisome-proliferator-activated-receptor-gamma-ppar%C3%AE-induced-by-chlorination
#9
Sai Zheng, Jiachen Shi, Jing Zhang, Yi Yang, Jianying Hu, Bing Shao
Bisphenol S (BPS), an alternative product to bisphenol A (BPA), has been the focus of increasing public concern due to its potential endocrine disrupting effect and its adverse effects related to metabolic disorders such as obesity. The detection of its residue in drinking water supply systems suggests that BPS can be chlorinated; however, whether its endocrine disrupting effect can be disrupted by this chlorination remains unclear. In the present study, we identified the byproducts of the reaction of BPS with chlorine and assessed the effect of the main byproducts on peroxisome proliferator-activated receptor gamma (PPARγ)...
January 5, 2018: Water Research
https://www.readbyqxmd.com/read/29331427/water-soluble-mercury-ion-sensing-based-on-the-thymine-hg2-thymine-base-pair-using-retroreflective-janus-particle-as-an-optical-signaling-probe
#10
Hyeong Jin Chun, Saemi Kim, Yong Duk Han, Dong Woo Kim, Ka Ram Kim, Hyo-Sop Kim, Jae-Ho Kim, Hyun C Yoon
Herein, we report an optical sensing platform for mercury ions (Hg2+) in water based on the integration of Hg2+-mediated thymine-thymine (T-T) stabilization, a biotinylated stem-loop DNA probe, and a streptavidin-modified retroreflective Janus particle (SA-RJP). Two oligonucleotide probes, including a stem-loop DNA probe and an assistant DNA probe, were utilized. In the absence of Hg2+, the assistant DNA probe does not hybridize with the stem-loop probe due to their T-T mismatch, so the surface-immobilized stem-loop DNA probe remains a closed hairpin structure...
January 6, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29330516/drinking-by-amphibious-fish-convergent-evolution-of-thirst-mechanisms-during-vertebrate-terrestrialization
#11
Yukitoshi Katayama, Tatsuya Sakamoto, Kazuhiro Saito, Hirotsugu Tsuchimochi, Hiroyuki Kaiya, Taro Watanabe, James T Pearson, Yoshio Takei
Thirst aroused in the forebrain by angiotensin II (AngII) or buccal drying motivates terrestrial vertebrates to search for water, whereas aquatic fish can drink surrounding water only by reflex swallowing generated in the hindbrain. Indeed, AngII induces drinking through the hindbrain even after removal of the whole forebrain in aquatic fish. Here we show that AngII induces thirst also in the amphibious mudskipper goby without direct action on the forebrain, but through buccal drying. Intracerebroventricular injection of AngII motivated mudskippers to move into water and drink as with tetrapods...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329982/gongylonema-pulchrum-infection-in-the-human-oral-cavity-a-case-report-and-literature-review
#12
REVIEW
Liu Xiaodan, Wang Zhensheng, Han Ying, Liu Hongwei, Jin Jianqiu, Zhou Peiru, Su Sha, Yan Zhimin
Gongylonema infection is a zoonotic disease occurring throughout the world and is mainly caused by consumption of contaminated water and raw food. Adult Gongylonema worms can exist as parasites in the human body for up to 10 years and cause symptoms of local irritation in the oral cavity, esophagus, and pharynx. Herein, we report a rare case in which live Gongylonema pulchrum was detected and extracted from the oral cavity of a woman. The pathogen was confirmed as G. pulchrum on the basis of microscopic examination and morphologic analysis...
December 8, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29329710/hydride-generation-coupled-with-thioglycolic-acid-coated-gold-nanoparticles-as-simple-and-sensitive-headspace-colorimetric-assay-for-visual-detection-of-sb-iii
#13
Tesfaye Tolessa, Zhi-Qiang Tan, Jing-Fu Liu
Antimony (Sb) is a toxic element which causes different health problems including cardiac problems and lung cancer in humans, and its levels in surface water can be noticeably increased to 100 μg/L typically in the proximity of anthropogenic sources. Thus, besides instrumental techniques, it is of great significance to develop a simple, sensitive and selective analytical method for direct analysis of Sb(III) at trace level without the need of any expensive and/or complicated instrumentations and sample preparation processes...
April 3, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29329561/strongyloides-stercoralis-and-hookworm-co-infection-spatial-distribution-and-determinants-in-preah-vihear-province-cambodia
#14
Armelle Forrer, Virak Khieu, Fabian Schär, Penelope Vounatsou, Frédérique Chammartin, Hanspeter Marti, Sinuon Muth, Peter Odermatt
BACKGROUND: Strongyloides stercoralis and hookworm are two soil-transmitted helminths (STH) that are highly prevalent in Cambodia. Strongyloides stercoralis causes long-lasting infections and significant morbidity but is largely neglected, while hookworm causes the highest public health burden among STH. The two parasites have the same infection route, i.e. skin penetration. The extent of co-distribution, which could result in potential high co-morbidities, is unknown in highly endemic settings like Cambodia...
January 12, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29329102/arsenic-exposure-from-drinking-water-and-urinary-metabolomics-associations-and-long-term-reproducibility-in-bangladesh-adults
#15
Fen Wu, Liang Chi, Hongyu Ru, Faruque Parvez, Vesna Slavkovich, Mahbub Eunus, Alauddin Ahmed, Tariqul Islam, Muhammad Rakibuz-Zaman, Rabiul Hasan, Golam Sarwar, Joseph H Graziano, Habibul Ahsan, Kun Lu, Yu Chen
BACKGROUND: Chronic exposure to inorganic arsenic from drinking water has been associated with a host of cancer and noncancer diseases. The application of metabolomics in epidemiologic studies may allow researchers to identify biomarkers associated with arsenic exposure and its health effects. OBJECTIVE: Our goal was to evaluate the long-term reproducibility of urinary metabolites and associations between reproducible metabolites and arsenic exposure. METHODS: We studied samples and data from 112 nonsmoking participants (58 men and 54 women) who were free of any major chronic diseases and who were enrolled in the Health Effects of Arsenic Longitudinal Study (HEALS), a large prospective cohort study in Bangladesh...
January 12, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29329087/occurrence-of-perfluoroalkyl-substances-pfas-in-garden-produce-at-homes-with-a-history-of-pfas-contaminated-drinking-water
#16
Deanna P Scher, James E Kelly, Carin A Huset, Kitrina M Barry, Richard W Hoffbeck, Virginia L Yingling, Rita B Messing
The decades-long disposal of manufacturing waste containing perfluoroalkyl substances (PFAS) in landfills resulted in contamination of groundwater serving as the drinking water supply for the eastern Twin Cities metropolitan region. While measures were taken to reduce the levels of PFAS in the drinking water, questions remained about possible non-drinking water pathways of exposure in these communities. The Minnesota Department of Health (MDH) investigated whether PFAS in water used for yard and garden irrigation results in elevated concentrations of PFAS in soil and home-grown produce...
December 29, 2017: Chemosphere
https://www.readbyqxmd.com/read/29328039/influence-of-metabolic-syndrome-on-condition-of-microcirculatory-bed-of-oral-cavity
#17
O Denga, T Pyndus, V Gargin, S Schneider
Metabolic syndrome (MS) can be characterized as the clustering of combination of impaired glucose regulation, metabolic disorders accompanied by abdominal obesity, hyperglycemia, high blood pressure and dyslipidemia. Detection of changes in microcirculatory bed (MCB) of oral cavity in metabolic syndrome could be important for completion of gap for developing of adequate therapeutical measure for prevention of pathological periodontal disorder that was the purpose of our study. We performed experimental investigation with modulation of MS (on white male rats 1...
December 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29325802/utilization-of-large-volume-zwitterionic-hydrophilic-interaction-liquid-chromatography-for-the-analysis-of-polar-pharmaceuticals-in-aqueous-environmental-samples-benefits-and-limitations
#18
Lise Boulard, Georg Dierkes, Thomas Ternes
Benefits and limitations of HILIC were studied for the analysis of extreme polar organic contaminants in aqueous environmental matrices. A sensitive analytical method was developed and validated for the detection of 11 pharmaceuticals, 15 pharmaceutical metabolites and transformation products and the artificial sweetener acesulfame in aqueous environmental samples. The analytical method consisted of a simple and non-specific sample preparation based on freeze-drying followed by detection with large injection volume (70 μL) zwitterionic HILIC-ESI-MS/MS...
December 11, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29324247/mglu5-dependent-modulation-of-anxiety-during-early-withdrawal-from-binge-drinking-in-adult-and-adolescent-male-mice
#19
Kaziya M Lee, Michal A Coelho, MacKayla A Class, Karen K Szumlinski
Binge alcohol-drinking elicits symptoms of negative affect such as anxiety upon cessation, which is a source of negative reinforcement for perpetuating this pattern of alcohol abuse. Binge-induced anxiety during early (24 h) withdrawal is associated with increased expression of metabotropic glutamate receptor 5 (mGlu5) within the nucleus accumbens shell (AcbSh) of adult male mice, but was unchanged in anxiety-resilient adolescents. Herein, we determined the role of mGlu5 signaling in withdrawal-induced anxiety via pharmacological manipulation using the mGlu5 negative allosteric modulator MTEP and the positive allosteric modulator CDPPB...
January 5, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29324084/protein-association-of-%C3%AE-n-methylamino-l-alanine-in-triticum-aestivum-via-irrigation
#20
Valeska Contardo-Jara, Torsten Schwanemann, Maranda Esterhuizen-Londt, Stephan Pflugmacher
Bioaccumulation of several cyanotoxins has been observed in numerous food webs. More recently, the neurotoxic, non-proteinogenic amino acid β-N-methylamino-L-alanine (BMAA) was shown to biomagnify in marine food webs. It was thus necessary to assess whether a human exposure risk via a terrestrial food source could exist. As shown for other cyanotoxins, spray irrigation of crop plants with cyanobacterial bloom-contaminated surface water poses the risk of toxin transfer into edible plant parts. Therefore, in the present study, we evaluated a possible transfer of BMAA via spray irrigation into the seeds of one of the world's most widely cultivated crop plants, Triticum aestivum...
January 11, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
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