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https://www.readbyqxmd.com/read/29667343/abstracts-of-the-british-maternal-fetal-medicine-society-bmfms-20th-annual-conference-2018-19th-20th-april-2018-brighton-uk
#1
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No abstract text is available yet for this article.
April 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29666681/implications-of-early-pregnancy-obesity-on-maternal-fetal-and-neonatal-health-retrospective-cohort-study-from-oman
#2
Anita Zutshi, Jayasree Santhosh, Julie Sheikh, Fareeha Naeem, Ahmed Al-Hamedi, Shahla Khan, Eishthiag Al-Said
Objectives: This study aimed to determine the prevalence of early pregnancy obesity among Omani women and to review maternal antenatal complications, intrapartum and postpartum events and neonatal complications among such women in comparison to women of normal weight. Methods: This retrospective cohort study included 2,652 pregnant Omani women who delivered at the Royal Hospital, Muscat, Oman, between November 2011 and April 2012. The patients' electronic medical records were reviewed for antenatal, intrapartum and postpartum data...
February 2018: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29658496/-gestastres-cohort-study-protocol-on-the-effects-of-stress-during-pregnancy-by-measuring-the-cortisol-in-women-s-and-newborn-s-hair
#3
Rafael A Caparros-Gonzalez, Inmaculada García-García, Juan Carlos Mariñas-Lirola, Maria Isabel Peralta-Ramírez
The aim was to present the longitudinal study protocol on the effects of perinatal stress from conception to one year of age. Stress is associated to psychopathological, cardiovascular and inmunological diseases. During pregnancy, the activation of the Hipotalamic-Pituitary-Adrenal results in an increased release of cortisol. Stress during pregnancy is related to maternal, fetal and infant negative outcomes that can last a lifetime. Nevertheless, contradictory findings have been reported. In this longitudinal study maternal stress is assessed from a sample of 807 pregnant women through hair cortisol levels and psychological question- naires during the three trimesters of pregnancy...
April 16, 2018: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/29657243/distinct-pattern-of-th17-treg-cells-in-pregnant-women-with-a-history-of-unexplained-recurrent-spontaneous-abortion
#4
Jinfeng Qian, Na Zhang, Jing Lin, Caiyan Wang, Xinyao Pan, Lanting Chen, Dajin Li, Ling Wang
The aim of the current study was to determine the pattern of immune cells and related functional molecules in peripheral blood and at the maternal-fetal interface in women with unexplained recurrent spontaneous abortion (URSA). In part I, 155 women were included and divided into four groups: non-pregnant controls with no history of URSA (NPCs), pregnant controls with no history of URSA (PCs), non-pregnant women with a history of URSA (NPUs), and pregnant women with a history of URSA (PUs). Venous blood samples were collected and analyzed...
April 15, 2018: Bioscience Trends
https://www.readbyqxmd.com/read/29651447/impaired-gal-9-dysregulates-the-pbmc-induced-th1-th2-imbalance-in-abortion-prone-matings
#5
Mengzhou He, Ming Jiang, Yuan Zhou, Fanfan Li, Meitao Yang, Yao Fan, Yin Xie, Rajluxmee Beejadhursing, Ling Feng, Dongrui Deng
Recurrent miscarriage is defined as the loss of 3 or more consecutive pregnancies; however, the underlying immunologic mechanisms that trigger pregnancy loss remain largely unelucidated. Galectin-9 (Gal-9) may modulate a variety of biologic functions and play an important role in Th1/Th2 immune deviation. To analyze the mechanism of Gal-9 in abortion, we used the classical abortion-prone mouse model (DBA/2-mated CBA/J mice) to detect the expression of Gal-9 at the maternal-fetal interface. We also mimicked the immune environment of pregnancy by culturing trophoblast cells with peripheral blood mononuclear cells (PBMCs) to explore how Gal-9 might be involved in the pathogenesis of abortion...
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/29643846/lilrb4-decrease-on-udcs-exacerbate-abnormal-pregnancy-outcomes-following-toxoplasma-gondii-infection
#6
Shaowei Zhan, Jing Zheng, Haixia Zhang, Mingdong Zhao, Xianbing Liu, Yuzhu Jiang, Chunyan Yang, Liqin Ren, Zhiqiang Liu, Xuemei Hu
Toxoplasma gondii ( T. gondii ) infection in early pregnancy can result in miscarriage, dead fetus, and other abnormalities. The LILRB4 is a central inhibitory receptor in uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface. In this study, T. gondii -infected human primary uDCs and T. gondii -infected LILRB4-/- pregnant mice were utilized. The immune mechanisms underlying the role of LILRB4 on uDCs were explored in the development of abnormal pregnancy outcomes following T...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29642803/expression-of-n-acetylglucosaminyltransferase-iii-promotes-trophoblast-invasion-and-migration-in-early-human-placenta
#7
Qinyin Deng, Xiru Liu, Zhongmei Yang, Lan Xie
INTRODUCTION: Trophoblast migration and invasion at the maternal-fetal interface are crucial events for normal placentation and successful pregnancy. This progress is well controlled by many placenta-specific factors. Inadequate trophoblast invasion results in poor placenta plantation or even complications such as preeclampsia. It has been shown that N-acetylglucosaminyltransferase III (GnT-III) participates in tumor invasion and metastasis as a suppressor; however, the expression of GnT-III and its role in normal pregnancy is unclear...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29626976/chronic-histiocytic-intervillositis-clinical-biochemical-and-radiological-findings-an-observational-study
#8
Lawrence Koby, Sarah Keating, Ann Kinga Malinowski, Rohan D'Souza
INTRODUCTION: Chronic histiocytic intervillositis (CHI) of the placenta although rare, has a high recurrence rate, is associated with serious adverse pregnancy outcomes and has no available treatment. This study aims to determine clinical, biochemical and radiological factors associated with CHI, to guide management of subsequent pregnancies. METHODS: This retrospective observational study included consecutive cases with a histopathologic diagnosis of CHI after 18 weeks of gestation, between 2001 and 2014, and no controls...
April 2018: Placenta
https://www.readbyqxmd.com/read/29626438/aquaporin-1-gene-deletion-affects-the-amniotic-fluid-volume-and-composition-as-well-as-the-expression-of-other-aquaporin-water-channels-in-placenta-and-fetal-membranes
#9
Hui Luo, Ailan Xie, Ying Hua, Jing Wang, Yanyun Liu, Xueqiong Zhu
OBJECTIVE: To explore the role of aquaporin 1 (AQP1) in regulation of amniotic fluid volume and composition. To investigate the effects of AQP1 gene knockout on expression of other aquaporin water channels (AQP3, AQP8 and AQP9) in placentas and fetal membranes. METHODS: Mice were sacrificed at 9.5, 13.5 and 16.5 gestational day (GD). Amniotic fluid volume, osmolality and composition, fetal membranes, placental and fetal weights as well as placenta areas were recorded in AQP1 homozygote conceptus group, heterozygote conceptus group and wild-type group, respectively...
April 4, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29621925/transport-kinetics-of-chromium-in-perfused-human-placental-lobule-in-late-gestation-in-vitro-study
#10
B Al-Sannan, M Nandakumaran, J Al-Harmi, M Al-Shammari, M Fouda
OBJECTIVE: Reports relating to maternal-fetal transport kinetics of chromium, an essential trace element in the human pregnancies are scanty. Hence, we thought it interesting to investigate the transport kinetics of this trace element in the human placenta in late gestation in vitro. METHODS: Human placentae were collected immediately after delivery from normal uncomplicated pregnancies. Chromium chloride solution (GFS Chem Inc, Ohio, USA) at 10 times the physiological concentrations and antipyrine (Sigma Chem Co...
April 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29621911/incidence-and-natural-history-of-preeclampsia-eclampsia-at-the-university-maternity-of-antananarivo-madagascar-high-prevalence-of-the-early-onset-condition
#11
Andriamanetsiarivo Tanjona Ratsiatosika, Eric Razafimanantsoa, Valéry Bruno Andriantoky, Noël Ravoavison, Rakotovao Andrianampanalinarivo Hery, Malik Boukerrou, Silvia Iacobelli, Pierre-Yves Robillard
OBJECTIVES: To investigate the incidence of early - (delivery < 34 weeks) (EOP) versus late-onset (delivery ≥ 34 weeks) (LOP) in Madagascar. STUDY DESIGN: Eight months observational study of all preeclamptic/eclamptic women delivering at the maternity of the University Hospital of Befelatanana, Antananarivo, Madagascar. Sociodemographical and obstetrical risk factors are analysed. RESULTS: Over the study period, we found 142 combined preeclampsia/eclampsia among 4316 births (incidence 3...
April 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29621406/is-a-vegetarian-diet-safe-to-follow-during-pregnancy-a-systematic-review-and-meta-analysis-of-observational-studies
#12
Chang Tan, Yudi Zhao, Suqing Wang
BACKGROUND: Whether a vegetarian diet is appropriate for pregnancy remains unclear. OBJECTIVE: This study aimed to determine the association between vegetarian diet during pregnancy and various maternal-fetal outcomes. METHOD: PubMed-Medline, EMBASE, and Cochrane Library databases were searched for relevant articles published by August 30, 2017. Quantitative data were analyzed by a random-effects model with pooled odds ratios or weighted mean difference (WMD) and 95% confidence interval as aggregate estimations...
April 5, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29618777/three-macrophage-subsets-are-identified-in-the-uterus-during-early-human-pregnancy
#13
Xiangxiang Jiang, Mei-Rong Du, Min Li, Hongmei Wang
Macrophages are crucial for a successful pregnancy, and malfunctions of decidual macrophages correlate with adverse pregnancy outcomes, such as spontaneous abortion and preeclampsia. Previously, decidual macrophages were often thought to be a single population. In the present study, we identified three decidual macrophage subsets, CCR2-CD11cLO (CD11clow , ~80%), CCR2-CD11cHI (CD11chigh , ~5%), and CCR2+CD11cHI (CD11chigh , 10-15%), during the first trimester of human pregnancy by flow cytometry analysis. CCR2-CD11cLO macrophages are widely distributed in the decidua, while CCR2-CD11cHI and CCR2+CD11cHI macrophages are primarily detected close to extravillous trophoblast cells according to immunofluorescence staining...
April 4, 2018: Cellular & Molecular Immunology
https://www.readbyqxmd.com/read/29610266/causative-effects-of-genetically-determined-high-maternal-fetal-endothelin-1-on-preeclampsia-like-conditions-in-mice
#14
Feng Li, Masao Kakoki, Marcela Smid, Kim Boggess, Jennifer Wilder, Sylvia Hiller, Carol Bounajim, Scott E Parnell, Kathleen K Sulik, Oliver Smithies, Nobuyo Maeda-Smithies
Endothelin-1 (ET-1) is implicated in the pathophysiology of preeclampsia. An association between an EDN1 gene polymorphism with high ET-1 and preeclampsia was reported in humans, but their cause and effect relationships have not been defined. We examined the pregnancy effects in mice with a modified Edn1 allele that increases mRNA stability and thus ET-1 production. Heterozygous Edn1 H/+ females showed no obvious abnormalities before pregnancy, but when mated with wild-type (WT) males developed a full spectrum of preeclampsia-like phenotypes, including increased systolic blood pressure, proteinuria, glomerular endotheliosis, and intrauterine fetal growth restriction...
April 2, 2018: Hypertension
https://www.readbyqxmd.com/read/29607328/maternal-fetal-and-neonatal-outcomes-in-pregnant-dengue-patients-in-mexico
#15
Carlos Machain-Williams, Eric Raga, Carlos M Baak-Baak, Sungmin Kiem, Bradley J Blitvich, Celso Ramos
To increase our understanding of the consequences of dengue virus infection during pregnancy, a retrospective analysis was performed on the medical records of all completed pregnancies (live births and pregnancy losses) at nine public hospitals in the Gulf of Mexico from January to October 2013. Eighty-two patients developed clinical, laboratory-confirmed dengue virus infections while pregnant. Of these, 54 (65.9%) patients were diagnosed with dengue without warning signs, 15 (18.3%) patients were diagnosed with dengue with warning signs, and 13 (15...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29607028/use-of-field-portable-ultrasonography-reveals-differences-in-developmental-phenology-and-maternal-egg-provisioning-in-two-sympatric-viviparous-snakes
#16
Amanda M Sparkman, Kenneth R Chism, Anne M Bronikowski, Lilly J Brummett, Lucia L Combrink, Courtney L Davis, Kaitlyn G Holden, Nicole M Kabey, David A W Miller
A thorough understanding of the life cycles underlying the demography of wild species is limited by the difficulty of observing hidden life-history traits, such as embryonic development. Major aspects of embryonic development, such as the rate and timing of development, and maternal-fetal interactions can be critical features of early-life fitness and may impact population trends via effects on individual survival. While information on development in wild snakes and lizards is particularly limited, the repeated evolution of viviparity and diversity of reproductive mode in this clade make it a valuable subject of study...
March 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29601303/the-opioid-epidemic-and-pregnancy-implications-for-anesthetic-care
#17
Britany L Raymond, Bradley T Kook, Michael G Richardson
PURPOSE OF REVIEW: This review summarizes evolving knowledge regarding adverse maternal, fetal, and neonatal effects of opioid exposure during pregnancy, and current treatment options for opioid use disorder (OUD). Maternal and fetal implications of maternal opioid maintenance with methadone and buprenorphine are described. Finally, acute and chronic pain management strategies in opioid-tolerant parturients are reviewed. RECENT FINDINGS: Opioid use among parturients has risen dramatically, with opioid use during pregnancy as high as 20%...
March 29, 2018: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29588487/trophoblast-derived-cxcl16-induces-m2-macrophage-polarization-that-in-turn-inactivates-nk-cells-at-the-maternal-fetal-interface
#18
Xiao-Qiu Wang, Wen-Jie Zhou, Xin-Xin Hou, Qiang Fu, Da-Jin Li
Decidual macrophages (dMΦ) are distinct from the conventional macrophages present in other tissues and express M2 macrophage markers, but the molecular mechanisms of formation and the roles of M2 MΦ during pregnancy have not been completely elucidated. The crosstalk between decidual natural killer cells (dNK) and dMΦ plays an important role in the maintenance of maternal-fetal immune tolerance. Here, CXCL16 derived from first-trimester trophoblast cells induces the polarization of human M2 macrophages. The M2 MΦ polarized by CXCL16 exhibit decreased interleukin-15 production, which facilitates the inactivation of NK cells...
March 27, 2018: Cellular & Molecular Immunology
https://www.readbyqxmd.com/read/29587185/pregnancy-outcomes-among-women-with-epilepsy-a-retrospective-cohort-study
#19
Atiwat Soontornpun, Tararak Choovanichvong, Theera Tongsong
OBJECTIVE: The objective of this study was to compare adverse pregnancy outcomes between pregnancies that involve epilepsy and those that do not and are identified as normal for the purposes of this paper. METHODS: A retrospective cohort study was carried out by accessing the maternal-fetal medicine (MFM) database to identify and review records of singleton pregnancies with epilepsy but with no other underlying disease (study group). A parallel group of low-risk pregnancies was randomly allocated as the control group...
March 24, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29579522/the-relationship-of-maternal-fetal-attachment-and-postpartum-depression-a-longitudinal-study
#20
Mina Delavari, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirghafourvand
AIM: To determine the relationship between maternal-fetal attachment and postpartum depression. METHODS: This longitudinal study was done on 242 primiparous women in 2016. The data collection tools used included a socio-demographic characteristics questionnaire and Cranley's Maternal-Fetal Attachment Scale - which was completed at 32-37weeks of pregnancy - and obstetrics information questionnaire and the Edinburgh Postnatal Depression Scale -which was completed at 6-8weeks after birth...
April 2018: Archives of Psychiatric Nursing
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