Lioba Huelsboemer, Leonard Knoedler, Alejandro Kochen, Catherine T Yu, Helia Hosseini, Katharina S Hollmann, Ashley E Choi, Viola A Stögner, Samuel Knoedler, Henry C Hsia, Bohdan Pomahac, Martin Kauke-Navarro
Chronic, non-healing wounds represent a significant challenge for healthcare systems worldwide, often requiring significant human and financial resources. Chronic wounds arise from the complex interplay of underlying comorbidities, such as diabetes or vascular diseases, lifestyle factors, and genetic risk profiles which may predispose extremities to local ischemia. Injuries are further exacerbated by bacterial colonization and the formation of biofilms. Infection, consequently, perpetuates a chronic inflammatory microenvironment, preventing the progression and completion of normal wound healing...
April 18, 2024: Military Medical Research