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Nutrition therapy

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https://www.readbyqxmd.com/read/29449867/current-therapies-in-alleviating-liver-disorders-and-cancers-with-a-special-focus-on-the-potential-of-vitamin-d
#1
REVIEW
Shahida Khan, Ashraf Ali, Sarah Khan, Ahmed Bakillah, Ghazi Damanhouri, Aziz Khan, Ahmed Makki, Ibtehal AlAnsari, Naheed Banu
Background: Liver dysfunction is a topic of global concern with many advancing therapies being researched. Though vitamin D takes a center place, other therapies especially nutritional are also gaining ground. Vitamin D has gone beyond its role in skeletal disorders by showcasing its associations in other metabolic dysfunctions too. Result: Epidemiological evidences show a correlation between the status of vitamin D and different forms of cancer. Vitamin D receptors and alterations in gene expression appear decisive in the development of chronic liver disorders...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29448287/-significance-of-homocysteine-in-glaucoma
#2
Anselm Jünemann, Robert Rejdak, Bettina Hohberger
Endothelial dysfunction and vascular dysregulation play a role in the multifactorial pathogenesis of glaucomatous optic nerve atrophy. Hyperhomocysteinemia is a risk factor for endothelial dysfunction and is associated with primary open-angle glaucoma as well as secondary open-angle glaucoma in the pseudoexfoliation syndrome. This paper reviews the literature on the association between homocysteine metabolism and glaucomatous disease and explains the possible role of hyperhomocysteinemia in the pathogenesis and progression of glaucoma...
February 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29446858/enteral-nutrition-for-pediatric-crohn-s-disease-an-underutilized-therapy
#3
REVIEW
Ala K Shaikhkhalil, Wallace Crandall
Enteral nutrition (EN) for the treatment of Crohn's disease (CD) involves administration of a liquid nutrition product, administered orally or through tube feeding, while excluding typical dietary components. It is a safe and effective, but largely underused, therapy in the United States as a treatment for CD. EN is a particularly attractive option for pediatric CD as it avoids side effects of corticosteroids, improves growth, and may have a higher likelihood of achieving mucosal healing than some traditional medications...
February 15, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29445300/gastric-cancer-epidemiology-prevention-classification-and-treatment
#4
REVIEW
Robert Sitarz, Małgorzata Skierucha, Jerzy Mielko, G Johan A Offerhaus, Ryszard Maciejewski, Wojciech P Polkowski
Gastric cancer is the second most common cause of cancer-related deaths in the world, the epidemiology of which has changed within last decades. A trend of steady decline in gastric cancer incidence rates is the effect of the increased standards of hygiene, conscious nutrition, and Helicobacter pylori eradication, which together constitute primary prevention. Avoidance of gastric cancer remains a priority. However, patients with higher risk should be screened for early detection and chemoprevention. Surgical resection enhanced by standardized lymphadenectomy remains the gold standard in gastric cancer therapy...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29444656/implementation-of-a-successful-eradication-protocol-for-burkholderia-cepacia-complex-in-cystic-fibrosis-patients
#5
Bryan A Garcia, Jacque L Carden, Dana L Goodwin, Tim A Smith, Amit Gaggar, Kevin Leon, Veena B Antony, Steven M Rowe, George M Solomon
BACKGROUND: Infection with Burkholderia cepacia complex (Bcc) results in a heterogeneous clinical course ranging from asymptomatic colonization of the airways to fulminant respiratory failure in patients with cystic fibrosis (CF). Early eradication of Pseudomonas aeruginosa improves clinical outcomes. The efficacy and clinical outcomes following implementation of an eradication protocol for Bcc are less well understood. METHODS: We developed and implemented a single center Bcc eradication protocol that included an intensive combination of intravenous, inhaled, and oral antibiotic therapies based on in vitro sensitivities...
February 14, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29443400/barriers-to-nutrition-intervention-for-patients-with-a-traumatic-brain-injury-views-and-attitudes-of-medical-and-nursing-practitioners-in-the-acute-care-setting
#6
Lee-Anne Chapple, Marianne Chapman, Natalie Shalit, Andrew Udy, Adam Deane, Lauren Williams
BACKGROUND: Nutrition delivered to patients with a traumatic brain injury (TBI) is typically below prescribed amounts. While the dietitian plays an important role in the assessment and provision of nutrition needs, they are part of a multidisciplinary team. The views and attitudes of medical and nursing practitioners are likely to be crucial to implementation of nutrition to patients with TBI, but there is limited information describing these. METHODS: A qualitative exploratory approach was used to explore the views and attitudes of medical and nursing practitioners on nutrition for patients with TBI...
February 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29435843/nutrition-management-for-the-head-and-neck-cancer-patient
#7
Denise Ackerman, Meghan Laszlo, Arlene Provisor, Adern Yu
Head and neck cancer (HNC) patients often face multiple nutritional challenges before, during, and after treatment due to the close proximity of the cancer to organs that are vital for normal eating function. Common treatment-related side effects, such as dysphagia, odynophagia, dysgeusia, xerostomia, thick saliva, mucositis, nausea, and vomiting, all further impair the patient's ability to maintain adequate oral intake. Malnutrition and unintentional weight loss in HNC patients during and after treatment are associated with poorer treatment outcomes, increased morbidity and mortality, and poor quality of life, even in overweight and obese patients whose Body Mass Index (BMI) is not suggestive of malnutrition...
2018: Cancer Treatment and Research
https://www.readbyqxmd.com/read/29435836/oral-and-dental-health-in-head-and-neck-cancer-patients
#8
Joel B Epstein, Andrei Barasch
A diagnosis of head and neck cancer (HNC) is typically followed by therapy that is associated with immediate and long-lasting toxic consequences. HNC patients' oral health needs may be complex and are best addressed in multidisciplinary collaborative teams including surgical, medical, and radiation oncologists, dental providers, nutrition, speech/swallow specialists, and physical therapists. Oral health maintenance also requires patient compliance and caregiver support. The role of dental providers begins prior to cancer diagnosis and continues through survivorship...
2018: Cancer Treatment and Research
https://www.readbyqxmd.com/read/29435286/prognostic-nutritional-index-as-a-predictor-of-survival-in-patients-with-recurrent-cervical-cancer
#9
Naoyuki Ida, Keiichiro Nakamura, Masayuki Saijo, Tomoyuki Kusumoto, Hisashi Masuyama
Systemic inflammatory responses (SIRs) can help predict survival in various cancers. The present study investigated the accuracy of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and prognostic nutritional index (PNI) in predicting survival for patients with recurrent cervical cancer. A retrospective review of prognoses examined the associations among NLR, PLR, and PNI, and clinical characteristics and survival in 79 patients with recurrent cervical cancer after undergoing concurrent chemoradiation therapy (CCRT) or radical hysterectomies with or without CCRT...
February 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29434976/prediction-of-long-term-survival-rates-in-patients-undergoing-curative-resection-for-solitary-hepatocellular-carcinoma
#10
Yi Cao, Zhelong Jiang, Shaohu Wang, Haoyang Zhang, Yi Jiang, Lizhi Lv
The present study developed a novel laboratory-based algorithm to predict long-term survival rates in patients undergoing curative resection for solitary hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). The present study included 426 patients with solitary HBV-related HCC who underwent surgery for primary tumors at a single center between 2003 and 2012. Demographic characteristics, laboratory analysis, clinical pathology and immunohistochemistry of topoisomerase II-a and Ki67 were analyzed. A simple prognostic risk calculator was developed using regression coefficients from multivariate models...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29434904/epigenetic-actions-of-environmental-factors-and-promising-drugs-for-cancer-therapy
#11
Zhong-Tian Bai, Bing Bai, Jun Zhu, Cui-Xia Di, Xun Li, Wen-Ce Zhou
Carcinogenesis is known to be primarily associated with gene mutations. Recently, increasing evidence has suggested that epigenetic events also serve crucial roles in tumor etiology. Environmental factors, including nutrition, toxicants and ethanol, are involved in carcinogenesis through inducing epigenetic modifications, such as DNA methylation, histone deacetylase and miRNA regulation. Studying epigenetic mechanisms has facilitated the development of early diagnostic strategies and potential therapeutic avenues...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29434066/perioperative-antimicrobial-therapy-in-preventing-infectious-complications-following-pancreatoduodenectomy
#12
Savio George Barreto, Amanjeet Singh, Azhar Perwaiz, Tanveer Singh, Manish Kumar Singh, Sunil Sharma, Adarsh Chaudhary
Background & objectives: Infectious complications have been reported to occur in up to 45 per cent of patients, following pancreatoduodenectomy (PD). The incidence of perioperative infectious and overall complications is higher in patients undergoing preoperative invasive endoscopic procedures. The aim of the study was to compare the role of a carbapenem administered as three-once daily perioperative doses on infectious complications in patients at high risk for these complications versus those at low risk...
October 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29433770/acid-folic-and-pregnancy-a-mandatory-supplementation
#13
Morgane Valentin, Perrine Coste Mazeau, Michel Zerah, Pierre François Ceccaldi, Alexandra Benachi, Dominique Luton
Neural tube defects (NTD) occur in 0.5 to 2 per 1000 pregnancies with various handicaps for the affected child. It is now well established that folic acid deficiency (absolute or relative) is a predisposing factor to this type of malformation. Several randomized controlled trials showed that high-dose folic acid (4mg) is an essential factor for prevention of neural tube defects recurrence and significantly prevents the first occurrence of neural tube defects with a lower dose (0.4mg). Other etiologies can favor the occurrence of NTD such as MTHFR polymorphism, some antiepileptic therapies, obesity and pregestational mellitus diabetes...
February 9, 2018: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29433514/loss-of-skeletal-muscle-mass-during-neoadjuvant-treatments-correlates-with-worse-prognosis-in-esophageal-cancer-a-retrospective-cohort-study
#14
Tommi Järvinen, Ilkka Ilonen, Juha Kauppi, Jarmo Salo, Jari Räsänen
BACKGROUND: Nutritional deficits, cachexia, and sarcopenia are extremely common in esophageal cancer. The aim of this article was to assess the effect of loss of skeletal muscle mass during neoadjuvant treatment on the prognosis of esophageal cancer patients. METHODS: Esophageal cancer patients (N = 115) undergoing neoadjuvant therapy and surgery between 2010 and 2014 were identified from our surgery database and retrospectively analyzed. Computed tomography imaging of the total cross-sectional muscle tissue measured at the third lumbar level defined the skeletal muscle index, which defined sarcopenia (SMI < 52...
February 12, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29432326/exercise-improves-physical-activity-and-comorbidities-in-obese-adults-with-asthma
#15
Patrícia Duarte Freitas, Aline Grandi Silva, Palmira Gabriele Ferreira, Analuci da Silva, João Marcos Salge, Regina Maria Carvalho-Pinto, Alberto Cukier, Claudia M Brito, Marcio C Mancini, Celso R F Carvalho
INTRODUCTION: Obese adults with asthma have an increased number of comorbidities and reduced daily life physical activity (DLPA), which may worsen asthma symptoms. Exercise is recommended to improve asthma outcomes; however, the benefits of exercise for psychosocial comorbidities and physical activity levels in obese adults with asthma have been poorly investigated. OBJECTIVE: To assess the effects of exercise on DLPA, asthma symptoms and psychosocial comorbidities in obese adults with asthma...
February 9, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29432297/should-fecal-microbial-transplantation-be-used-in-the-icu
#16
Stephen A McClave, Jayshil Patel, Neal Bhutiani
PURPOSE OF REVIEW: Maintaining gut barrier defenses, modulating immune responses, and supporting the role of commensal microbiota are major factors influencing outcome in critical illness. Of these, maintaining a commensal 'lifestyle' and preventing the emergence of a virulent pathobiome may be most important in reducing risk of infection and multiple organ failure. RECENT FINDINGS: The polymeric formulas utilized for enteral nutrition in the ICU are absorbed high in the gastrointestinal tract and may not reach the microbial burden in the cecum where their effect is most needed...
February 9, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29432296/gut-microbiota-puppeteer-of-the-host-juvenile-growth
#17
Martin Schwarzer
PURPOSE OF REVIEW: This review focuses on the recent discoveries about the impact of intestinal microbiota on mammalian host juvenile growth. RECENT FINDINGS: Intestinal microbiota is a powerful modulator of many facets of multicellular host's physiology. Recent results from human field studies and animal research have clearly shown that not only the nutrition, but also the intestinal microbiota impacts host postnatal growth kinetics. Absence of microbiome leads to stunted growth in mammalian gnotobiotic models and changes in the composition of the intestinal microbiota can impact the postnatal growth kinetics both positively and negatively under normal nutritional conditions as well as in undernutrition...
February 9, 2018: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29430435/esophageal-endoscopic-vacuum-therapy-with-enteral-feeding-using-a-sengstaken-blakemore-tube
#18
So Young Lee, Kun Woo Kim, Jae-Ik Lee, Dong-Kyun Park, Kook-Yang Park, Chul-Hyun Park, Kuk-Hui Son
Early diagnosis followed by primary repair is the best treatment for spontaneous esophageal perforation. However, the appropriate management of esophageal leakage after surgical repair is still controversial. Recently, the successful adaptation of vacuum-assisted closure therapy, which is well established for the treatment of chronic surface wounds, has been demonstrated for esophageal perforation or leakage. Conservative treatment methods require long-term fasting with total parenteral nutrition or enteral feeding through invasive procedures, such as percutaneous endoscopic gastrostomy or a feeding jejunostomy...
February 2018: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29430225/superior-mesenteric-artery-syndrome-improved-by-enteral-nutritional-therapy-according-to-the-controlling-nutritional-status-score
#19
Kazuhiro Takehara, Kazuhiro Sakamoto, Rina Takahashi, Masaya Kawai, Shingo Kawano, Shinya Munakata, Kiichi Sugimoto, Makoto Takahashi, Yutaka Kojima, Tetsu Fukunaga, Yoshiaki Kajiyama, Seiji Kawasaki
Superior mesenteric artery syndrome (SMAS) is a relatively rare disease that involves bowel obstruction symptoms, such as vomiting and gastric distension, owing to the compression of the third portion of the duodenum from the front by the superior mesenteric artery (SMA) and from the rear by the abdominal aorta and the spine. SMAS is diagnosed on the basis of an upper gastrointestinal examination series indicating the obstruction of the third portion of the duodenum or a computed tomography scan indicating the narrowing of the branch angle between the aorta and the SMA (i...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29429529/management-and-prevention-of-refeeding-syndrome-in-medical-inpatients-an-evidence-based-and-consensus-supported-algorithm
#20
Natalie Friedli, Zeno Stanga, Alison Culkin, Martin Crook, Alessandro Laviano, Lubos Sobotka, Reto W Kressig, Jens Kondrup, Beat Mueller, Philipp Schuetz
OBJECTIVES: Refeeding syndrome (RFS) can be a life-threatening metabolic condition after nutritional replenishment if not recognized early and treated adequately. There is a lack of evidence-based treatment and monitoring algorithm for daily clinical practice. The aim of the study was to propose an expert consensus guideline for RFS for the medical inpatient (not including anorexic patients) regarding risk factors, diagnostic criteria, and preventive and therapeutic measures based on a previous systematic literature search...
March 2018: Nutrition
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