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Marat Fudim

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https://www.readbyqxmd.com/read/29754673/prevalent-digoxin-use-and-subsequent-risk-of-death-or-hospitalization-in-ambulatory-heart-failure-patients-with-a-reduced-ejection-fraction-findings-from-the-heart-failure-a-controlled-trial-investigating-outcomes-of-exercise-training-hf-action-randomized-controlled
#1
Andrew P Ambrosy, Ankeet S Bhatt, Amanda L Stebbins, Lisa M Wruck, Marat Fudim, Stephen J Greene, William E Kraus, Christopher M O'Connor, Ileana L Piña, David J Whellan, Robert J Mentz
BACKGROUND: Despite more than 200 years of clinical experience and a pivotal trial, recently published research has called into question the safety and efficacy of digoxin therapy in heart failure (HF). METHODS: HF-ACTION (ClinicalTrials.gov Number: NCT00047437) enrolled 2331 outpatients with HF and an EF ≤35% between April 2003 and February 2007 and randomized them to aerobic exercise training versus usual care. Patients were grouped according to prevalent digoxin status at baseline...
May 2018: American Heart Journal
https://www.readbyqxmd.com/read/29731118/post-traumatic-stress-disorder-and-heart-failure-in-men-within-the-veteran-affairs-health-system
#2
Marat Fudim, Lukasz P Cerbin, Srikant Devaraj, Tarek Ajam, Sunil V Rao, Masoor Kamalesh
Patients with post-traumatic stress disorder (PTSD) are at risk of multiple co-morbidities and are more likely to develop incident heart failure with reduced ejection fraction (HFrEF). The relation of PTSD with clinical outcomes in HFrEF is not established. US veterans diagnosed with HFrEF from January 2007 to January 2015 and treated nationwide in the Veterans Affairs (VA) Health System were included in the study. Patients with HFrEF were identified through International Classification of Diseases, Ninth Revision (ICD-9) codes...
April 11, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29717380/selective-vs-global-renal-denervation-a-case-for-less-is-more
#3
REVIEW
Marat Fudim, Asher A Sobotka, Yue-Hui Yin, Joanne W Wang, Howard Levin, Murray Esler, Jie Wang, Paul A Sobotka
PURPOSE OF REVIEW: Review the renal nerve anatomy and physiology basics and explore the concept of global vs. selective renal denervation (RDN) to uncover some of the fundamental limitations of non-targeted renal nerve ablation and the potential superiority of selective RDN. RECENT FINDINGS: Recent trials testing the efficacy of RDN showed mixed results. Initial investigations targeted global RDN as a therapeutic goal. The repeat observation of heterogeneous response to RDN including non-responders with lack of a BP reduction, or even more unsettling, BP elevations after RDN has raised concern for the detrimental effects of unselective global RDN...
May 1, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29450822/a-troubled-marriage-when-electrical-and-mechanical-dyssynchrony-don-t-go-along
#4
EDITORIAL
Marat Fudim, Salvador Borges-Neto
No abstract text is available yet for this article.
February 14, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29413443/cardiovascular-imaging-with-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-patients-with-fibroinflammatory-disorders
#5
Marat Fudim, Matthew P Thorpe, Leslie L Chang, E William St Clair, Lynne M Hurwitz Koweek, Andrew Wang
No abstract text is available yet for this article.
February 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29314460/sudden-cardiac-death-following-admission-for-acute-heart-failure-adding-insult-to-injury
#6
EDITORIAL
Andrew P Ambrosy, Marat Fudim, Ovidiu Chioncel
No abstract text is available yet for this article.
March 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29082629/aetiology-timing-and-clinical-predictors-of-early-vs-late-readmission-following-index-hospitalization-for-acute-heart-failure-insights-from-ascend-hf
#7
Marat Fudim, Christopher M O'Connor, Allison Dunning, Andrew P Ambrosy, Paul W Armstrong, Adrian Coles, Justin A Ezekowitz, Stephen J Greene, Marco Metra, Randall C Starling, Adriaan A Voors, Adrian F Hernandez, G Michael Felker, Robert J Mentz
AIMS: Patients hospitalized for heart failure (HF) are at high risk for 30-day readmission. This study sought to examine the timings and causes of readmission within 30 days of an HF hospitalization. METHODS AND RESULTS: Timing and cause of readmission in the ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure) trial were assessed. Early and late readmissions were defined as admissions occurring within 0-7 days and 8-30 days post-discharge, respectively...
February 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28862947/role-of-volume-redistribution-in-the-congestion-of-heart-failure
#8
REVIEW
Marat Fudim, Adrian F Hernandez, G Michael Felker
No abstract text is available yet for this article.
August 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28833780/stellate-ganglion-blockade-for-the-treatment-of-refractory-ventricular-arrhythmias-a-systematic-review-and-meta-analysis
#9
Marat Fudim, Richard Boortz-Marx, Arun Ganesh, Nathan H Waldron, Yawar J Qadri, Chetan B Patel, Carmelo A Milano, Albert Y Sun, Joseph P Mathew, Jonathan P Piccini
INTRODUCTION: Treatment refractory ventricular arrhythmias (VAs) are often driven and exacerbated by heightened sympathetic tone. We aim to conduct a systematic review and meta-analysis of published studies of a temporary percutaneous stellate ganglion block (SGB) on VA burden and defibrillation episodes in patients with treatment refractory VAs. METHODS: Relevant studies from January 1960 through May 2017 were identified in PubMed and Google Scholar. We performed a patient-level analysis using Student's t-test to compare outcomes before and after SGB...
December 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28799950/orthostatic-hypotension-in-patients-with-left-ventricular-assist-devices-acquired-autonomic-dysfunction
#10
Marat Fudim, Joseph G Rogers, Camille Frazier-Mills, Chetan B Patel
Contemporary left ventricular assist device (LVAD) technology uses nonphysiologic continuous flow to deliver blood into the circulation. This results in a reduction of pulsatility, which is implicated in some of the commonly associated side effects with LVAD therapy, including hypertension and gastrointestinal arterial-venous malformation with related bleeding. A less frequently observed side effect is orthostatic hypotension (OH) in patients supported with LVAD therapy. We present three cases of OH in patients with LVAD, followed by a discussion on how LVAD therapy may induce autonomic dysfunction...
August 8, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28608977/treating-cardiac-dysrhythmias-by-targeting-the-neck-off-target-or-on-the-right-track
#11
EDITORIAL
Marat Fudim, Jonathan P Piccini
No abstract text is available yet for this article.
June 13, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28479167/trajectory-of-congestion-metrics-by-ejection-fraction-in%C3%A2-patients-with-acute-heart-failure-from-the-heart-failure%C3%A2-network
#12
MULTICENTER STUDY
Andrew P Ambrosy, Ankeet S Bhatt, Dianne Gallup, Kevin J Anstrom, Javed Butler, Adam D DeVore, G Michael Felker, Marat Fudim, Stephen J Greene, Adrian F Hernandez, Jacob P Kelly, Marc D Samsky, Robert J Mentz
Differences in the clinical course of congestion by underlying ejection fraction (EF) have not been well-characterized in acute heart failure (AHF). A post hoc analysis was performed using pooled data from the Diuretic Optimization Strategies Evaluation in Acute Heart Failure, Cardiorenal Rescue Study in Acute Decompensated Heart Failure, and Renal Optimization Strategies Evaluation in Acute Heart Failure trials. All patients were admitted for a primary diagnosis of AHF. Patients were grouped as reduced EF ≤40%, borderline 40% < EF < 50%, or preserved EF ≥50%...
July 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28418555/transcatheter-aortic-valve-implantation-versus-surgical-aortic-valve-replacement
#13
COMMENT
Marat Fudim, Gerald S Bloomfield, Zainab Samad
No abstract text is available yet for this article.
April 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28360118/raising-the-pressure-hemodynamic-effects-of-splanchnic-nerve-stimulation
#14
Marat Fudim, Suraj Yalamuri, J Taylor Herbert, Peter R Liu, Manesh R Patel, Aaron Sandler
A number of cardiovascular and neurological diseases are characterized by a dysregulation of intravascular volume distribution. The veins and arteries of the visceral organs form the so-called splanchnic vascular compartment and are the largest reservoir for intravascular blood. The blood localized in the splanchnic compartment can be mobilized in and out of the compartment via passive compression or active neurohormonal recruitment. We studied the hemodynamic effects of splanchnic nerve stimulation during five cases of Irreversible Electroporation (IRE) in patients with pancreatic cancer...
March 30, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28034373/body-weight-change-during-and-after-hospitalization-for-acute-heart-failure-patient-characteristics-markers-of-congestion-and-outcomes-findings-from-the-ascend-hf-trial
#15
RANDOMIZED CONTROLLED TRIAL
Andrew P Ambrosy, Lukasz P Cerbin, Paul W Armstrong, Javed Butler, Adrian Coles, Adam D DeVore, Mark E Dunlap, Justin A Ezekowitz, G Michael Felker, Marat Fudim, Stephen J Greene, Adrian F Hernandez, Christopher M O'Connor, Philip Schulte, Randall C Starling, John R Teerlink, Adriaan A Voors, Robert J Mentz
OBJECTIVES: This study sought to examine the relationships between in-hospital and post-discharge body weight changes and outcomes among patients hospitalized for acute heart failure (AHF). BACKGROUND: Body weight changes during and after hospitalization for AHF and the relationships with outcomes have not been well characterized. METHODS: A post hoc analysis was performed of the ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure) trial, which enrolled patients admitted for AHF regardless of ejection fraction...
January 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28019045/autonomic-modulation-for-the-treatment-of-ventricular-arrhythmias-therapeutic-use-of-percutaneous-stellate-ganglion-blocks
#16
Marat Fudim, Richard Boortz-Marx, Chetan B Patel, Albert Y Sun, Jonathan P Piccini
Ventricular tachycardia (VT), ventricular fibrillation (VF), and electrical storm are commonly encountered emergency conditions in cardiac and surgical intensive care units. In most cases, recurrent ventricular arrhythmias or electrical storm are associated with a heightened sympathetic tone. These arrhythmias can be difficult to treat and may be refractory to beta-blockade, antiarrhythmic therapy, sedation, and mechanical hemodynamic support. While monomorphic ventricular tachycardia and PVC-triggered polymorphic ventricular tachycardia may sometimes be amenable to successful ablation, some patients may be too critically ill to make such an approach feasible...
April 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28017346/body-weight-change-during-and-after%C3%A2-hospitalization-for-acute-heart%C3%A2-failure-%C3%A2-patient-characteristics-markers-of-congestion-and-outcomes-findings-from-ascend-hf
#17
Andrew P Ambrosy, Lukasz P Cerbin, Paul W Armstrong, Javed Butler, Adrian Coles, Adam D DeVore, Mark E Dunlap, Justin A Ezekowitz, G Michael Felker, Marat Fudim, Stephen J Greene, Adrian F Hernandez, Christopher M O'Connor, Philip Schulte, Randall C Starling, John R Teerlink, Adriaan A Voors, Robert J Mentz
OBJECTIVES: This study sought to examine the relationships between in-hospital and post-discharge body weight changes and outcomes among patients hospitalized for acute heart failure (AHF). BACKGROUND: Body weight changes during and after hospitalization for AHF and the relationships with outcomes have not been well characterized. METHODS: A post hoc analysis was performed of the ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure) trial, which enrolled patients admitted for AHF regardless of ejection fraction...
November 30, 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/27866925/extracorporeal-membrane-oxygenation-support-and-post-heart-transplant-outcomes-among-united-states-adults
#18
MULTICENTER STUDY
Sandip Zalawadiya, Marat Fudim, Geetha Bhat, William Cotts, JoAnn Lindenfeld
BACKGROUND: Patients supported with extracorporeal membrane oxygenation (ECMO) are given priority listing status for heart transplant (HT). Data on post-HT outcomes for adults with ECMO support at the time of HT are limited. METHODS: We analyzed data from the United Network for Organ Registry (UNOS) registry for 157 ECMO-supported adults (age ≥ 18 years) undergoing HT after January 1, 2000. Data at the time of HT were examined for their association with post-transplant mortality using multivariable Cox proportional hazard analyses...
January 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27849844/201-outcomes-of-venoarterial-ecmo-for-adults-with-post-cardiotomy-cardiogenic-shock
#19
Nawar Al-Rawas, David Ranney, Lynn McGugan, Marat Fudim, Sade Bell, Annemarie Thompson, Desiree Bonadonna, Mani Daneshmand
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27647775/carotid-body-resection-for-sympathetic-modulation-in-systolic-heart-failure-results-from-first-in-man-study
#20
Piotr Niewinski, Dariusz Janczak, Artur Rucinski, Stanislaw Tubek, Zoar J Engelman, Pawel Piesiak, Przemyslaw Jazwiec, Waldemar Banasiak, Marat Fudim, Paul A Sobotka, Shahrokh Javaheri, Emma C J Hart, Julian F R Paton, Piotr Ponikowski
AIMS: Augmented reflex responses from peripheral chemoreceptors, which are mainly localized in the carotid bodies (CBs), characterize patients with systolic heart failure and contribute to adrenergic hyperactivation. We investigated whether surgical resection of CBs in these patients can be performed safely to decrease sympathetic tone. METHODS AND RESULTS: We studied 10 male patients with systolic heart failure (age, 59 ± 3 years; LVEF, 27 ± 7%) who underwent unilateral right-sided CB resection (four patients) or bilateral CB resection (six patients)...
March 2017: European Journal of Heart Failure
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