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https://www.readbyqxmd.com/read/29145297/therapeutic-effect-of-neoadjuvant-chemotherapy-combined-with-curettage-to-treat-distal-femoral-osteosarcoma-a-case-report
#1
Qi Lai, Conglin Ye, Tian Gao, Jun Xiao, An Xie, Xuqiang Liu, Xiaolong Yu, Jun Liu, Min Dai, Hucheng Liu, Bin Zhang
RATIONALE: Osteosarcoma is the most common malignant bone tumor in children and adolescents. Metastasis occurs early, the mortality rate is high, and the tumor results in a tremendous physical, mental, and economic burden on patients. Therefore, the treatment of osteosarcoma has been important for orthopedic surgeons. However, treatment has always been a difficult problem globally. PATIENT CONCERN: We present the case of a 22-year-old girl with increasing local pain in the distal left thigh...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29137617/surgical-treatment-for-diffused-type-giant-cell-tumor-pigmented-villonodular-synovitis-about-the-ankle-joint
#2
Xingchen Li, Yang Xu, Yuan Zhu, Xiangyang Xu
BACKGROUND: Diffused-type giant cell tumor(Dt-GCT) is a rare, aggressive disorder of the joint synovium, bursa and tendon sheaths. Osseous erosions and subchondral cysts may develop as the result of synovium infiltration in Dt-GCT. We present a retrospective study of a series of patients who are diagnosed with Dt-GCT about the ankle joint, there clinical outcome is evaluated in this study. MATERIAL AND METHOD: Fifteen patients with radiologically and histologically confirmed Dt-GCT about the ankle joint were identified in our foot and ankle department...
November 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29136257/risk-factors-for-pathological-fracture-and-metastatic-epidural-spinal-cord-compression-in-patients-with-spinal-metastases
#3
Catherine S Hibberd, Gerald M Y Quan
Vertebral pathological fracture and metastatic epidural spinal cord compression (MESCC) due to metastatic cancer inevitably cause pain, neurological deficit, impaired function, and decreased quality of life and are indications for surgery. In such cases, earlier surgical intervention has the potential to prevent permanent neurological deficit and disability and to maintain function and quality of life. Therefore, the aim of this study was to identify and evaluate risk factors for pathological fracture and MESCC in patients with spinal metastases...
November 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/29136254/completion-of-multiple-fellowships-by-orthopedic-surgeons-analysis-of-the-american-board-of-orthopaedic-surgery-certification-database
#4
J Mason DePasse, Alan H Daniels, Wesley Durand, Brandon Kingrey, John Prodromo, Mary K Mulcahey
Orthopedic surgeons have become increasingly subspecialized, and recent studies have shown that American Board of Orthopaedic Surgery (ABOS) Step II applicants are performing a higher percentage of their cases within their chosen subspecialties. However, these studies focused exclusively on surgeons who have completed a single fellowship; little data exist on those who pursue a second fellowship. All applicants to the ABOS Part II examination from 2004 to 2016 were classified by their self-reported fellowship training history using the ABOS Part II examination database...
November 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/29129354/surgical-management-and-outcomes-of-patients-with-bone-metastases-in-germ-cell-tumors-a-case-series
#5
Alessandro Nini, Marcus Konieczny, Christian Winter, Achim Lusch, Rüdiger Krauspe, Peter Albers
OBJECTIVE: To report perioperative and oncological outcomes of patients with nodal and bone involvement treated with postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) and simultaneous bone resection (BR). PATIENTS AND METHODS: Between 2008 and 2016, 14 consecutive unselected TC patients with nodal and bone involvement underwent PC-RPLND and BR. Surgery was performed together with orthopedic surgeons. Standard PC-RPLNDs were performed in 4 patients...
November 9, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29127246/non-oncologic-applications-of-pet-ct-and-pet-mr-in-musculoskeletal-orthopedic-and-rheumatologic-imaging-general-considerations-techniques-and-radiopharmaceuticals
#6
Ali Gholamrezanezhad, Kyle Basques, Ali Batouli, Mojtaba Olyaie, George Matcuk, Abass Alavi, Hossein Jadvar
Positron Emission Tomography (PET) is often underutilized in the field of musculoskeletal imaging, with key reasons including the excellent performance of conventional musculoskeletal MRI, the limited spatial resolution of PET, and the lack of reimbursement for PET for non-oncologic musculoskeletal indications. However, with improvements in PET/CT and PET/MR imaging over the last decade as well as an increased understanding of the pathophysiology of musculoskeletal diseases, there is an emerging potential for PET as a primary or complementary modality in the management of rheumatologic and orthopedic patients...
November 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29125819/how-successful-are-turkish-orthopedists-in-complying-with-time-limit-in-scientific-presentations
#7
Nadir Yalçın, Enes Uluyardımcı, İbrahim Bozkurt
OBJECTIVES: This study aims to investigate the durations of scientific presentations and factors affecting the rates of exceeding the time limit in presentations at 26th Turkish National Congress of Orthopedics and Traumatology, which is one of Turkey's largest nationally organized orthopedics and traumatology meetings in terms of the numbers of speakers and participators. MATERIALS AND METHODS: Speech durations of Turkish orthopedists and the rates of these durations against the durations specified in the schedule were calculated...
December 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/29109029/transcriptional-profile-of-human-macrophages-stimulated-by-ultra-high-molecular-weight-polyethylene-particulate-debris-of-orthopedic-implants-uncovers-a-common-gene-expression-signature-of-rheumatoid-arthritis
#8
Mohamad Alaa Terkawi, Masanari Hamasaki, Daisuke Takahashi, Masahiro Ota, Ken Kadoya, Tomoyo Yutani, Keita Uetsuki, Tsuyoshi Asano, Tohru Irie, Ryuta Arai, Tomohiro Onodera, Masahiko Takahata, Norimasa Iwasaki
Osteolysis is a serious postoperative complication of total joint arthroplasty that leads to aseptic loosening and surgical revision. Osteolysis is a chronic destructive process that occurs when host macrophages recognize implant particles and release inflammatory mediators that increase bone-resorbing osteoclastic activity and attenuate bone-formation osteoblastic activity. Although much progress has been made in understanding the molecular responses of macrophages to implant particles, the pathways/signals that initiate osteolysis remain poorly characterized...
November 3, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29097955/thoracic-schwannoma-in-an-adult-male-presenting-with-thoracic-pain-a-case-report
#9
Andrew M Rodgers, Kim B Khauv
Objective: The purpose of this case report was to describe a patient presenting with back pain subsequently diagnosed with thoracic schwannoma. Clinical Features: A 45-year-old male presented to a chiropractic practice with mid-back, low back, and sacroiliac pain. Orthopedic examination revealed joint dysfunction in the thoracic-sacroiliac region with normal findings on neurologic examination. An initial diagnosis of thoracic spinal pain and sacroiliac sprain and strain was made...
September 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29079234/primary-tumor-and-tumor-like-lesions-of-bones-of-the-foot-single-center-experience-of-166-cases
#10
Devrim Özer, Osman Emre Aycan, Sait Turgay Er, Rahime Tanrıtanır, Yavuz Arıkan, Yavuz Selim Kabukçuoğlu
Primary bone tumors of the foot are rare lesions. The purpose of the present study was to evaluate the clinical manifestations, treatment modalities, and recurrences of various primary bone tumors of the foot from a specialized center for orthopedic oncology. Among 3681 musculoskeletal tumor cases, which were diagnosed and surgically treated in our hospital from 1983 to 2013, 166 primary tumor and tumor-like bone lesions of the foot (4.5%) were retrospectively reviewed regarding age, gender, localization, biopsy-revealed diagnosis, applied treatment modalities, follow-up period, and recurrence, if any...
November 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29052751/-prevention-of-infections-due-to-musculoskeletal-allografts
#11
REVIEW
A Pruß
Transplantation of musculoskeletal tissues is widely used in the treatment of extensive defects of the musculoskeletal system, especially in orthopedics for exchange of prostheses, surgical interventions on the spine and in traumatology for reconstruction after extensive tumor resections. A danger after transplantation is the potential transmission of clinically relevant pathogens. Tissue banks have therefore established a safety level approach for musculoskeletal tissue transplants, which includes donor selection, laboratory testing, tissue procurement, tissue processing, tissue storage and quality assurance...
November 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29044582/provider-views-on-the-management-of-ewing-sarcoma-of-the-spine-and-pelvis
#12
Chong Zhu, Kristofor A Olson, Michael Roth, David S Geller, Richard G Gorlick, Jonathan Gill, Nadia N Laack, R L Randall
BACKGROUND: Curative therapy for ES requires both chemotherapy and local control of primary tumor. There is no universally accepted standard approach to local control modalities. This survey was conducted to determine practice patterns and factors influencing the choice to offer various local control modalities to patients with ES of the spine and pelvis. METHODS: The survey consisted of four scenarios involving a 15-year-old girl who presented with Ewing sarcoma of thoracic vertebra, sacrum, iliac wing, and acetabulum with or without neurologic compromise...
October 16, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29038715/one-stage-surgical-excision-of-a-huge-bilateral-multiple-osteochondroma-of-the-hip-a-case-report
#13
Afshin Taheriazam, Amin Saeidinia
Osteochondroma or hereditary multiple exostoses is the most common benign bone tumor and is usually found in young patients. Osteochondromata of the proximal femur or hip have been reported in 30% to 90% of patients with hereditary multiple exostoses. This article presents a 25-year-old-male referred to our orthopedic clinic with a complaint of pain in both groins for the last four years which has deteriorated in the past 6 months by limitation of range of motion. Radiographic findings were consistent with huge hip osteochondroma and a histopathological report confirmed the diagnosis...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29033574/surgical-site-infections-following-instrumented-stabilization-of-the-spine
#14
Ulrike Dapunt, Caroline Bürkle, Frank Günther, Wojciech Pepke, Stefan Hemmer, Michael Akbar
BACKGROUND: Implant-associated infections are still a feared complication in the field of orthopedics. Bacteria attach to the implant surface and form so-called biofilm colonies that are often difficult to diagnose and treat. Since the majority of studies focus on prosthetic joint infections (PJIs) of the hip and knee, current treatment options (eg, antibiotic prophylaxis) of implant-associated infections have mostly been adapted according to these results. OBJECTIVE: The aim of this study was to evaluate patients with surgical site infections following instrumented stabilization of the spine with regard to detected bacteria species and the course of the disease...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29031873/does-specialty-matter-a-survey-on-176-italian-neurosurgeons-and-orthopaedic-spine-surgeons-confirms-similar-competency-for-common-spinal-conditions-and-supports-multidisciplinary-teams-in-comprehensive-and-complex-spinal-care
#15
Matteo Pejrona, Gabriele Ristori, Jorge Hugo Villafañe, Fabrizio Ernesto Pregliasco, Pedro Berjano
BACKGROUND CONTEXT: Spine surgery is a multi-faceted sub-speciality requiring a breadth of knowledge and skill from different branches of medicine for the treatment of pathologies varying from degenerative to deformity, oncological, and trauma. PURPOSE: The aim of the study was to investigate the self-perceived competency of spine surgeons in relation to different types of spinal procedures. STUDY DESIGN/SETTING: Survey study. METHODS: We conducted a survey on 176 surgeons (Orthopaedic surgeons and Neurosurgeons)...
October 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28978922/therapeutic-pcl-scaffold-for-reparation-of-resected-osteosarcoma-defect
#16
Ilaria E Palamà, Valentina Arcadio, Stefania D'Amone, Mariano Biasiucci, Giuseppe Gigli, Barbara Cortese
Osteosarcomas are highly malignant tumors, which develop rapid growth and local infiltration, inducing metastases that spread primarily in the lung. Treatment of these tumors is mainly based on pre- and post-operative chemotherapy and surgery of the primary tumor. Surgical resection though, generates bone defects. Reparation of these weaknesses presents formidable challenges to orthopedic surgery. Medicine regenerative grafts that act as both tumor therapy with constant local drug delivery and tissue regeneration may provide a new prospect to address this need...
October 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28965455/single-stage-deformity-correction-in-children-with-neurogenic-kyphoscoliosis-nuances-and-a-proposal-for-risk-stratification
#17
Suhas Udayakumaran, Sajesh K Menon, Chiazor U Onyia, Naveen Tahasildar
OBJECTIVE Neurogenic kyphoscoliosis in pediatric patients has varied causes and diverse management options. The most common management strategy is to stage the orthopedic and neurosurgical aspects of the correction at an interval of 3-6 months from each other. The aim of this study was to report the authors' experience with correction of deformity in children with associated neurological abnormalities requiring intervention as a single-stage surgical treatment. METHODS Of 591 pediatric patients with scoliosis treated at the Amrita Institute of Medical Sciences and Research Centre between January 2001 and January 2011, the authors identified all patients with neurogenic kyphoscoliosis who underwent deformity correction and a neurosurgical procedure in the same surgical session when they were younger than 15 years...
October 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28958177/use-of-minimally-invasive-spine-surgical-instruments-for-the-treatment-of-bone-tumors
#18
Russell A Reeves, Matthew C DeWolf, Peter J Shaughnessy, James B Ames, Eric R Henderson
Orthopedic oncologists often encounter patients with minor bony lesions that are difficult to access surgically and therefore require large exposures out of proportion to the severity of disease that confer significant patient morbidity. Minimally invasive surgical techniques offer the advantage of smaller incisions, shorter operative times, decreased tissue damage, and decreased costs. A variety of surgical procedures have emerged using minimally invasive technologies, particularly in the field of spine surgery...
October 4, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28948558/matrixins-in-the-salivary-fluid-of-patients-with-tumors-of-the-maxillofacial-region-during-orthopedic-rehabilitation-with-different-prosthetic-structures
#19
E V Kochurova, V N Nikolenko
Dental and immunological features of the influence of various prosthetic structures of orthopedic prostheses on tissues and organs of the maxillofacial region were evaluated by the parameters of expression of oral fluid biomarkers. Healthy people without tumor and somatic diseases and patients with neoplasms of maxillofacial area in need of dental rehabilitation were examined before and in 2 weeks and 3 months after treatment. Certain regularities in the reaction of biomarkers to orthopedic prostheses were observed: a decrease in activity of MMP-2 and MMP-8 and their inhibitors or an increase in MMP-9; an increase in activity of biomarkers at early terms and a decrease in delayed terms after prosthetics...
September 26, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28934543/long-term-results-of-intercalary-endoprosthetic-short-segment-fixation-following-extended-diaphysectomy
#20
Nicholas S Tedesco, Alexandra L Van Horn, Robert M Henshaw
Intercalary endoprosthetic reconstruction following diaphyseal resection of osseous tumors offers functional advantages through preservation of native joints adjacent to the resected defect. Use of such implants is restricted by the amount of bone available for stem fixation adjacent to the defect. This study aimed to determine whether short osseous segment fixation with acceptable outcomes and complication rate can be reliably achieved with a customized intercalary endoprosthesis following extended diaphysectomy...
September 21, 2017: Orthopedics
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