keyword
MENU ▼
Read by QxMD icon Read
search

Iron loading

keyword
https://www.readbyqxmd.com/read/29329289/burkholderia-pseudomallei-modulates-host-iron-homeostasis-to-facilitate-iron-availability-and-intracellular-survival
#1
Imke H E Schmidt, Claudia Gildhorn, Martha A L Böning, Vera A Kulow, Ivo Steinmetz, Antje Bast
BACKGROUND: The control over iron homeostasis is critical in host-pathogen-interaction. Iron plays not only multiple roles for bacterial growth and pathogenicity, but also for modulation of innate immune responses. Hepcidin is a key regulator of host iron metabolism triggering degradation of the iron exporter ferroportin. Although iron overload in humans is known to increase susceptibility to Burkholderia pseudomallei, it is unclear how the pathogen competes with the host for the metal during infection...
January 12, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29327431/enhanced-bone-regeneration-and-visual-monitoring-via-super-paramagnetic-iron-oxide-nanoparticle-scaffold-in-rats
#2
Shuying Hu, Yi Zhou, Yantao Zhao, Yang Xu, Feimin Zhang, Ning Gu, Junqing Ma, Mark A Reynolds, Yang Xia, Hockin H K Xu
A main challenge for use of scaffolds in bone engineering involves non-invasive monitoring in vivo and enhanced bone regeneration. The tissue-repair effect of super-paramagnetic iron oxide nanoparticles (SPIONs) was demonstrated previously by our group. However, testing in vivo is needed to confirm in vitro results. Here, SPIONs loaded gelatin sponge (GS) was used as a scaffold (SPIONs-GS) and implanted in the incisor sockets of Sprague-Dawley rats. Incisor sockets filled with nothing and filled with GS served as controls...
January 12, 2018: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29327191/iron-impregnated-zeolite-catalyst-for-efficient-removal-of-micropollutants-at-very-low-concentration-from-meurthe-river
#3
Hawraa Ayoub, Thibault Roques-Carmes, Olivier Potier, Bachar Koubaissy, Steve Pontvianne, Audrey Lenouvel, Cédric Guignard, Emmanuel Mousset, Hélène Poirot, Joumana Toufaily, Tayssir Hamieh
In this paper, for the first time, faujasite Y zeolite impregnated with iron (III) was employed as a catalyst to remove a real cocktail of micropollutants inside real water samples from the Meurthe river by the means of the heterogeneous photo-Fenton process. The catalyst was prepared by the wet impregnation method using iron (III) nitrate nonahydrate as iron precursor. First, an optimization of the process parameters was conducted using phenol as model macro-pollutant. The hydrogen peroxide concentration, the light wavelength (UV and visible) and intensity, the iron loading immobilized, as well as the pH of the solution were investigated...
January 11, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29324800/hepcidin-deficiency-and-iron-deficiency-do-not-alter-tuberculosis-susceptibility-in-a-murine-m-tb-infection-model
#4
Rachel Harrington-Kandt, Elena Stylianou, Lucy A Eddowes, Pei Jin Lim, Lisa Stockdale, Nawamin Pinpathomrat, Naomi Bull, Janet Pasricha, Marta Ulaszewska, Yulia Beglov, Sophie Vaulont, Hal Drakesmith, Helen McShane
Tuberculosis (TB), caused by the macrophage-tropic pathogen Mycobacterium tuberculosis (M.tb) is a highly prevalent infectious disease. Since an immune correlate of protection or effective vaccine have yet to be found, continued research into host-pathogen interactions is important. Previous literature reports links between host iron status and disease outcome for many infections, including TB. For some extracellular bacteria, the iron regulatory hormone hepcidin is essential for protection against infection...
2018: PloS One
https://www.readbyqxmd.com/read/29320951/glutathione-conjugated-polyethylenimine-on-the-surface-of-fe3o4-magnetic-nanoparticles-as-a-theranostic-agent-for-targeted-and-controlled-curcumin-delivery
#5
Navid Aeineh, Fahimeh Salehi, Mohammad Akrami, Firouzeh Nemati, Masoumeh Alipour, Milad Ghorbani, Banafsheh Nikfar, Fatemeh Salehian, Nader Riyahi Alam, Seyed Esmaeil Sadat Ebrahimi, Alireza Foroumadi, Mehdi Khoobi, Mohammadreza Rouini, Maryam Dibaei, Ismaeil Haririan, Mohammad Reza Ganjali, Saeed Safaei
Theranostics with the ability to simultaneous monitoring of treatment progress and controlled delivery of therapeutic agents has become as an emerging therapeutic paradigm in cancer therapy. In this study, we have developed a novel surface functionalized iron oxide nanoparticle using polyethyleneimine (PEI) and glutathione (GSH) for targeted curcumin (CUR) delivery and acceptable pH sensitive character. The developed magnetic nanoparticles (MNPs) were physicochemically characterized by FT-IR, XRD, FE-SEM and TEM...
January 11, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29313480/malaria-and-iron-load-at-the-first-antenatal-visit-in-the-rural-south-kivu-democratic-republic-of-the-congo-is-iron-supplementation-safe-or-could-it-be-harmful
#6
Esto Bahizire, Umberto D'Alessandro, Michèle Dramaix, Nicolas Dauby, Fabrice Bahizire, Kanigula Mubagwa, Philippe Donnen
We investigated the relationship between malaria infection and iron status in 531 pregnant women in South Kivu, Democratic Republic of the Congo. Sociodemographic data, information on morbidity, and clinical data were collected. A blood sample was collected at the first antenatal visit to diagnose malaria and measure serum ferritin (SF), soluble transferrin receptor, C-reactive protein, and α1-acid-glycoprotein. Malaria prevalence was 7.5%. Median (interquartile range) SF (adjusted for inflammation) was significantly higher in malaria-infected (82...
January 8, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29307060/combination-effect-of-sponge-iron-and-calcium-nitrate-on-severely-eutrophic-urban-landscape-water-an-integrated-study-from-laboratory-to-fields
#7
Guan-Bai Wang, Yi Wang, Ying Zhang
In this study, the in situ restoration of urban landscape water through the combined application of sponge iron (SI) and calcium nitrate (CN) was conducted in the Xi'an Moat of China. The combination effect of SI and CN on the phosphorus (P) control was explored through laboratory and field experiments. Results showed that the optimum mass ratio of SI and CN was 4:1, and the optimum dosage of combined SI and CN was 1.4 g/L for controlling eutrophication in the water body at Xi'an Moat. The field experiment demonstrated that SI and CN efficiently controlled P concentration in overlying and interstitial water and obtained a maximum efficiency of 88...
January 6, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29306091/remediation-of-incomplete-nitrification-and-capacity-increase-of-biofilters-at-different-drinking-water-treatment-plants-through-copper-dosing
#8
Florian B Wagner, Peter Borch Nielsen, Rasmus Boe-Hansen, Hans-Jørgen Albrechtsen
Drinking water treatment plants based on groundwater may suffer from incomplete ammonium removal, which deteriorates drinking water quality and constrains water utilities in the operation of their plants. Ammonium is normally removed through nitrification in biological granular media filters, and recent studies have demonstrated that dosing of copper can stimulate the removal of ammonium. Here, we investigated if copper dosing could generically improve ammonium removal of biofilters, at treatment plants with different characteristics...
December 27, 2017: Water Research
https://www.readbyqxmd.com/read/29304001/microstructure-and-sliding-wear-behaviour-of-in-situ-tic-reinforced-composite-surface-layers-fabricated-on-ductile-cast-iron-by-laser-alloying
#9
Damian Janicki
TiC-reinforced composite surface layers (TRLs) on a ductile cast iron EN-GJS-700-2 grade (DCI) substrate were synthesized using a diode laser surface alloying with a direct injection of titanium powder into the molten pool. The experimental results were compared with thermodynamic calculations. The TRLs having a uniform distribution of the TiC particles and their fraction up to 15.4 vol % were achieved. With increasing titanium concentration in the molten pool, fractions of TiC and retained austenite increase and the shape of TiC particles changes from cubic to dendritic form...
January 5, 2018: Materials
https://www.readbyqxmd.com/read/29303566/silicate-binding-and-precipitation-on-iron-oxyhydroxides
#10
Masakazu Kanematsu, Glenn Waychunas, Jean-François Boily
Silica-bearing waters in nature often alter the reactivity of mineral surfaces via deposition of Si complexes and solids. In this work, Fourier transform infrared (FTIR) spectroscopy was used to identify hydroxo groups at goethite (-FeOOH) and lepidocrocite (-FeOOH) surfaces that are targeted by ligand exchange reactions with monomeric silicate species. Measurements of samples first reacted in aqueous solutions then dried under N2(g) enabled resolution of the signature O-H stretching bands of singly (OH), doubly- (μ-OH) and triply-coordinated (μ3-OH)...
January 5, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29299866/nitrobenzene-reduction-using-nanoscale-zero-valent-iron-supported-by-polystyrene-microspheres-with-different-surface-functional-groups
#11
Lixia Li, Shasha Zhang, Bing Lu, Fang Zhu, Jian Cheng, Zhihao Sun
Three polystyrene (PS) resin microspheres supported nanoscale zero-valent iron (nZVI), i.e., nZVI@PS, nZVI@PS-Cl, and nZVI@PS-N, were prepared and characterized by FT-IR, XPS, SEM, EDS, and weighing method. The functional groups on the carriers showed obvious influence on the loading quantity, the micro morphology, and the reduction efficiency of these supported nZVI. The best hybrid reducer was nZVI@PS-N. The load quantity of nZVI was 0.2476 g/g, and some of them were dispersed and the others remained as particles (≤ 50 nm)...
January 3, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29299614/cortical-and-subcortical-morphometric-and-iron-changes-in-relapsing-remitting-multiple-sclerosis-and-their-association-with-white-matter-t2%C3%A2-lesion-load-a%C3%A2-3-tesla-magnetic-resonance-imaging-study
#12
Ali Al-Radaideh, Imad Athamneh, Hadeel Alabadi, Majed Hbahbih
INTRODUCTION: This study was carried out to investigate the global and regional morphometric and iron changes in grey matter (GM) of multiple sclerosis (MS) patients and link them to the white matter (WM) lesions in a multimodal magnetic resonance imaging approach. MATERIAL AND METHODS: The study involved 30 relapsing-remitting MS (RRMS) patients along with 30 age-matched healthy controls (HC) who were scanned on a 3T Siemens Trio system. The scanning protocol included a 3D, high resolution T1, T2, and T2*-weighted sequences...
January 3, 2018: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29297954/palladium-loaded-cucurbit-7-uril-modified-iron-oxide-nanoparticles-for-c-c-cross-coupling-reactions
#13
Erwann Guenin, Farah Benyettou Benyettou, Hassan Traboulsi, Laurence Motte Motte, Javed Mazer, Renu Pasricha Pasricha, John-Carl Olsen Olsen, Ali Trabolsi
Cucurbit[7]uril modified iron oxide nanoparticles (CB[7]NPs) were loaded with palladium to form nano-catalysts (Pd@CB[7]NPs) that, with microwave heating, catalysed Suzuki-Miyaura, Sonogashira, and Mizoroki-Heck cross coupling reactions. All reactions were run in environmentally benign 1/1 ethanol/water solvent under convenient aerobic conditions. In a preliminary screening, all conversions and yields were uniformly high with turn over frequencies (TOF) ranging from 64 to 7360 h-1. The nano-catalysts could be recovered with a magnet and reused several times (6 times for Suzuki Miayura reaction) without loss of activity...
January 3, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29291487/adsorptive-removal-of-arsenic-by-novel-iron-olivine-composite-insights-into-preparation-and-adsorption-process-by-response-surface-methodology-and-artificial-neural-network
#14
Partha S Ghosal, Krishna V Kattil, Manoj K Yadav, Ashok K Gupta
Olivine, a low-cost natural material, impregnated with iron is introduced in the adsorptive removal of arsenic. A wet impregnation method and subsequent calcination were employed for the preparation of iron/olivine composite. The major preparation process parameter, viz., iron loading and calcination temperature were optimized through the response surface methodology coupled with a factorial design. A significant variation of adsorption capacity of arsenic (measured as total arsenic), i.e., 63.15 to 310.85 mg/kg for arsenite [As(III)T] and 76...
December 28, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29290806/multimodal-theranostic-nanoformulations-permit-magnetic-resonance-bioimaging-of-antiretroviral-drug-particle-tissue-cell-biodistribution
#15
Bhavesh D Kevadiya, Christopher Woldstad, Brendan M Ottemann, Prasanta Dash, Balasrinivasa R Sajja, Benjamin Lamberty, Brenda Morsey, Ted Kocher, Rinku Dutta, Aditya N Bade, Yutong Liu, Shannon E Callen, Howard S Fox, Siddappa N Byrareddy, JoEllyn M McMillan, Tatiana K Bronich, Benson J Edagwa, Michael D Boska, Howard E Gendelman
RATIONALE: Long-acting slow effective release antiretroviral therapy (LASER ART) was developed to improve patient regimen adherence, prevent new infections, and facilitate drug delivery to human immunodeficiency virus cell and tissue reservoirs. In an effort to facilitate LASER ART development, "multimodal imaging theranostic nanoprobes" were created. These allow combined bioimaging, drug pharmacokinetics and tissue biodistribution tests in animal models. METHODS: Europium (Eu3+)- doped cobalt ferrite (CF) dolutegravir (DTG)- loaded (EuCF-DTG) nanoparticles were synthesized then fully characterized based on their size, shape and stability...
2018: Theranostics
https://www.readbyqxmd.com/read/29290351/red-meat-intake-in-chronic-kidney-disease-patients-two-sides-of-the-coin
#16
REVIEW
Denise Mafra, Natalia A Borges, Ludmila Ferreira Medeiros de Franca Cardozo, Juliana S Anjos, Ana Paula Black, Cristiane Moraes, Peter Bergman, Bengt Lindholm, Peter Stenvinkel
Red meat is an important dietary source of high biological value protein and micronutrients such as vitamins, iron, and zinc that exert many beneficial functions. However, high consumption of animal protein sources, especially red meat, results in an increased intake of saturated fat, cholesterol, iron, and salt, as well as an excessive acid load. Red meat intake may lead to an elevated production of uremic toxins by the gut microbiota, such as trimethylamine n-oxide (TMAO), indoxyl sulfate, and p-cresyl sulfate...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29285401/multifunctional-stimuli-responsive-polymer-gated-iron-and-gold-embedded-silica-nano-golf-balls-nanoshuttles-for-targeted-on-demand-theranostics
#17
Liping Wang, Grace Jang, Deependra Kumar Ban, Vrinda Sant, Jay Seth, Sami Kazmi, Nirav Patel, Qingqing Yang, Joon Lee, Woraphong Janetanakit, Shanshan Wang, Brian P Head, Gennadi Glinsky, Ratneshwar Lal
Multi-functional nanoshuttles for remotely targeted and on-demand delivery of therapeutic molecules and imaging to defined tissues and organs hold great potentials in personalized medicine, including precise early diagnosis, efficient prevention and therapy without toxicity. Yet, in spite of 25 years of research, there are still no such shuttles available. To this end, we have designed magnetic and gold nanoparticles (NP)-embedded silica nanoshuttles (MGNSs) with nanopores on their surface. Fluorescently labeled Doxorubicin (DOX), a cancer drug, was loaded in the MGNSs as a payload...
2017: Bone Research
https://www.readbyqxmd.com/read/29281175/novel-starbon-hacs-supported-n-heterocyclic-carbene-iron-iii-catalyst-for-efficient-conversion-of-fructose-to-hmf
#18
Avtar Singh Matharu, Suleiman Ahmed, Badriya Al-Monthery, Duncan Macquarrie, Yoon-Sik Lee, Yohan Kim
: Iron-nitrogen heterocyclic carbenes (Fe-NHCs) have come to the fore because of their ability to be employed in diverse catalytic applications ranging from C-C cross-coupling and C-X bond formation to substitution, reduction, polymerization, and dehydration. The detailed synthesis, characterisation and application of novel heterogeneous Fe-NHC catalysts immobilised on mesoporous expanded starch and Starbon™ 350 for facile fructose to HMF conversion is reported. Both catalyst types showed good performance for the dehydration of fructose to HMF when the reaction was explored at 100 ◦C and varying time (10 min, 20 min, 0...
December 27, 2017: ChemSusChem
https://www.readbyqxmd.com/read/29280410/iron-balance-and-iron-supplementation-for-the-female-athlete-a-practical-approach
#19
Charles R Pedlar, Carlo Brugnara, Georgie Bruinvels, Richard Burden
Maintaining a positive iron balance is essential for female athletes to avoid the effects of iron deficiency and anaemia and to maintain or improve performance. A major function of iron is in the production of the oxygen and carbon dioxide carrying molecule, haemoglobin, via erythropoiesis. Iron balance is under the control of a number of factors including the peptide hormone hepcidin, dietary iron intake and absorption, environmental stressors (e.g. altitude), exercise, menstrual blood loss and genetics. Menstruating females, particularly those with heavy menstrual bleeding are at an elevated risk of iron deficiency...
December 27, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/29279245/an-optimized-low-cost-protocol-for-standardized-production-of-iron-free-apoferritin-nanocages-with-high-protein-recovery-and-suitable-conformation-for-nanotechnological-applications
#20
Italo Moglia, Margarita Santiago, Álvaro Olivera-Nappa, Mónica Soler
Ferritin is a globular protein that consists of 24 subunits forming a hollow nanocage structure that naturally stores iron oxyhydroxides. Elimination of iron atoms to obtain the empty protein called apoferritin is the first step to use this organic shell as a nanoreactor for different nanotechnological applications. Different protocols have been reported for apoferritin formation, but some are time consuming, others are difficult to reproduce and protein recovery yields are seldom reported. Here we tested several protocols and performed a complete material characterization of the apoferritin products using size exclusion chromatography, UV-vis spectroscopy, inductively coupled plasma optical emission spectrometry and dynamic light scattering...
November 21, 2017: Journal of Inorganic Biochemistry
keyword
keyword
54101
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"