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https://www.readbyqxmd.com/read/29207894/maternal-and-neonatal-outcomes-related-to-iron-supplementation-or-iron-status-a-summary-of-meta-analyses
#1
Sehar Iqbal, Cem Ekmekcioglu
BACKGROUND: Iron deficiency is the most abundant nutritional deficiency in the world and is discussed to be associated with adverse pregnancy outcomes. The objective of this review was to perform an umbrella summary of meta-analyses to evaluate the effects and associations of iron supplementation or iron status on maternal and birth/neonatal outcomes. METHODS: A literature search was conducted on PubMed and Scopus by two reviewers without temporal restriction. Systematic reviews and meta-analyses of studies evaluating (1) the effects of multimicronutrient compared to iron + folic acid supplementations on maternal and birth/neonatal outcomes (2), the association of dietary iron intake or hemoglobin or ferritin status regarding the risk for maternal (gestational diabetes mellitus (GDM)) and birth/neonatal outcomes, and (3) the effects of iron supplementation on pregnancy and birth/neonatal outcomes, were included in this review...
December 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29065736/investigation-of-possible-maternal-and-fetal-factors-which-affect-umbilical-coiling-index
#2
Muberra Namli Kalem, Ziya Kalem, Nilufer Akgun, Ebru Yuce, Hatice Aktas
AIM: The aim of this study was to investigate the possible maternal and fetal factors which affect the Umbilical Coiling Index (UCI). METHODS: This prospective, observational, analytic study was conducted using the data of 380 women with term pregnancy and newborns who presented at a University Hospital. Hemoglobin (Hb), ferritin, iron, and the total iron binding capacity (TIBC) of the maternal blood were measured, and transferrin saturation was estimated based on the ratio between serum iron and TIBC...
October 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28720232/meta-analysis-of-the-predictive-factors-of-postpartum-fatigue
#3
Hanan A Badr, Jaclene A Zauszniewski
PURPOSE: Nearly 64% of new mothers are affected by fatigue during the postpartum period, making it the most common problem that a woman faces as she adapts to motherhood. Postpartum fatigue can lead to serious negative effects on the mother's health and the newborn's development and interfere with mother-infant interaction. The aim of this meta-analysis was to identify predictive factors of postpartum fatigue and to document the magnitude of their effects using effect sizes. METHOD: We used two search engines, PubMed and Google Scholar, to identify studies that met three inclusion criteria: (a) the article was written in English, (b) the article studied the predictive factors of postpartum fatigue, and (c) the article included information about the validity and reliability of the instruments used in the research...
August 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28627190/-relationships-between-umbilical-vein-and-mother-iron-status
#4
Afaf Mezdoud, Abdel-Nacer Agli, Hayet Oulamara
INTRODUCTION: Iron is an essential micronutrient in the growing fetus. OBJECTIVE: The purpose of this study is to find the possible correlations that may exist between maternal and fetal iron status and newborn weight. MATERIAL AND METHODS: The study included 97 mothers scheduled to give birth by elective caesarean section in the central maternity of Tébessa (east of Algeria) between January and August 2014. The blood collection was sampled from the antecubital vein of the mother and the umbilical vein...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28063464/mitochondrial-ferritin-deficiency-reduces-male-fertility-in-mice
#5
Federica Maccarinelli, Maria Regoni, Fernando Carmona, Maura Poli, Esther G Meyron-Holtz, Paolo Arosio
Mitochondrial ferritin (FtMt) is a functional ferritin targeted to mitochondria that is highly expressed in the testis. To investigate the role of FtMt in the testis we set up a series of controlled matings between FtMt gene-deletion mice (FtMt-/-) with FtMt+/+ mice. We found that the number of newborns per litter and the fertility rate were strongly reduced for the FtMt-/- males, but not for the females, indicating that FtMt has an important role for male fertility. The morphology of the testis and of the spermatozoa of FtMt-/- mice was normal and we did not detect alterations in sperm parameters or in oxidative stress indices...
January 9, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/27321101/hepcidin-and-iron-status-in-pregnant-women-and-full-term-newborns-in-first-days-of-life
#6
Beata Kulik-Rechberger, Artur Kościesza, Elżbieta Szponar, Justyna Domosud
OBJECTIVES: The amount of iron is regulated by hepcidin. The aim of the study was to assess hepcidin concentrations in healthy pregnant women before delivery, in cord blood, and in 3-day-old newborns in relation to maternal and neonatal iron status. MATERIAL AND METHODS: The study group consisted of 44 mother-newborn pairs. Serum concentrations of hepcidin, ferritin, and transferrin receptor (sTfR) were assessed. RESULTS: Maternal hepcidin was significantly lower than cord blood (p < 0...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27166702/prenatal-exposure-to-multiple-pesticides-is-associated-with-auditory-brainstem-response-at-9months-in-a-cohort-study-of-chinese-infants
#7
Julie Sturza, Monica K Silver, Lin Xu, Mingyan Li, Xiaoqin Mai, Yankai Xia, Jie Shao, Betsy Lozoff, John Meeker
BACKGROUND: Pesticides are associated with poorer neurodevelopmental outcomes, but little is known about the effects on sensory functioning. METHODS: Auditory brainstem response (ABR) and pesticide data were available for 27 healthy, full-term 9-month-old infants participating in a larger study of early iron deficiency and neurodevelopment. Cord blood was analyzed by gas chromatography-mass spectrometry for levels of 20 common pesticides. The ABR forward-masking condition consisted of a click stimulus (masker) delivered via ear canal transducers followed by an identical stimulus delayed by 8, 16, or 64 milliseconds (ms)...
July 2016: Environment International
https://www.readbyqxmd.com/read/27119047/does-body-mass-index-in-pregnant-women-affect-laboratory-parameters-in-the-newborn
#8
Marjana Jerković Raguž, Jerko Brzica
Objective The objective of this study was to determine the effect of body mass index (BMI) during pregnancy in laboratory parameters in the serum of the three groups of pregnant women and in their newborns. Methods This prospective study is comparison between the three groups of pregnant women and their newborns categorized according to their BMI. The study included 128 pregnant women and their newborns. In this study, the concentration of blood count, iron, ferritin, and bilirubin were analyzed in the subjects...
April 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/26973190/-the-imbalance-of-metal-containing-proteins-and-free-metal-ions-in-the-amniotic-fluid-during-fetal-growth
#9
T N Pogorelova, V A Linde, V O Gunko, S N Selyutina
The levels of zinc, copper, iron, and magnesium ions, and some of their binding proteins have been investigated in an amniotic fluid under the fetal growth retardation (FGR). FGR, developed under conditions of placental insufficiency, is characterized by a decrease in the content of zinc, iron, and magnesium ions and by an increase in the copper content in the amniotic fluid in the II and III trimesters of pregnancy. During these trimesters the levels of ceruloplasmin, ferritin, and Ca2+,Mg2+-ATPase were lower in FGR, while the level of zinc-a-2-glycoprotein was higher than during the same periods of normal pregnancy...
January 2016: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/26970931/maternal-obesity-affects-inflammatory-and-iron-indices-in-umbilical-cord-blood
#10
Natalie C Dosch, Elyssa F Guslits, Morgan B Weber, Shannon E Murray, Barbara Ha, Christopher L Coe, Anthony P Auger, Pamela J Kling
OBJECTIVE: To determine the impact of maternal obesity and gestational weight gain across pregnancy on fetal indices of inflammation and iron status. STUDY DESIGN: Eighty-five healthy term newborns delivered via elective cesarean were categorized by 2 maternal body mass index (BMI) thresholds; above or below 30 kg/m(2) or above or below 35 kg/m(2). Umbilical cord plasma levels of C-reactive protein, interleukin (IL)-6, tumor necrosis factor (TNF)-α, ferritin, and hepcidin were assayed...
May 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/26836824/neonatal-hemochromatosis-in-monochorionic-twins
#11
L Korkmaz, O Baştuğ, G Daar, S Doğanay, K Deniz, S Kurtoğlu
Neonatal hemochromatosis (NH) is a form of neonatal liver failure caused by maternal-fetal alloimmune injury to hepatocytes. The etiology of neonatal hemochromatosis is not exactly understood. However, according to one theory neonatal hemochromatosis is believed to be an alloimmune disorder causing liver injury in the fetus. In order to diagnose neonatal hemochromatosis there are some criteria that should be taken into account, such as positive family history, high serum ferritin levels, high serum alpha-fetoprotein levels and siderosis demonstrated by histology or with magnetic resonance...
2015: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/26626049/the-prevalence-of-anemia-and-iron-deficiency-is-more-common-in-breastfed-infants-than-their-mothers-in-bhaktapur-nepal
#12
R K Chandyo, S Henjum, M Ulak, A L Thorne-Lyman, R J Ulvik, P S Shrestha, L Locks, W Fawzi, T A Strand
BACKGROUND/OBJECTIVES: Iron deficiency anemia is a widespread public health problem, particularly in low- and middle-income countries. Maternal iron status around and during pregnancy may influence infant iron status. We examined multiple biomarkers to determine the prevalence of iron deficiency and anemia among breastfed infants and explored its relationship with maternal and infant characteristics in Bhaktapur, Nepal. SUBJECTS/METHODS: In a cross-sectional survey, we randomly selected 500 mother-infant pairs from Bhaktapur municipality...
April 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26599151/maternal-prenatal-iron-status-and-tissue-organization-in-the-neonatal-brain
#13
Catherine Monk, Michael K Georgieff, Dongrong Xu, Xuejun Hao, Ravi Bansal, Hanna Gustafsson, Julie Spicer, Bradley S Peterson
BACKGROUND: Children prenatally exposed to inadequate iron have poorer motor and neurocognitive development. No prior study to our knowledge has assessed the influence of maternal prenatal iron intake on newborn brain tissue organization in full-term infants. METHODS: Third trimester daily iron intake was obtained using the Automated Self-Administered 24-h Dietary Recall with n = 40 healthy pregnant adolescents (aged 14-19 y). Cord blood ferritin was collected in a subsample (n = 16)...
March 2016: Pediatric Research
https://www.readbyqxmd.com/read/26545662/anemia-in-pregnancy-impact-on-weight-and-in-the-development-of-anemia-in-newborn
#14
Solange Augusta de Sá, Erica Willner, Tatiane Aguiar Duraes Pereira, Vanessa Rosse de Souza, Gilson Teles Boaventura, Vilma Blondet de Azeredo
INTRODUCTION: nutritional deficiencies are still a common problem during pregnancy causing anemia. Gestational anemia is still considered a public health problem in Brazil, because it is hazardous to both mother and fetus, and is associated with increased risk of maternal-fetal morbidity, as well as the nutritional status of child. OBJECTIVE: to evaluate the frequency of maternal gestational anemia in newborns and its relation to the nutritional status of the child at birth...
November 1, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/26529006/effects-of-fructans-from-mexican-agave-in-newborns-fed-with-infant-formula-a-randomized-controlled-trial
#15
RANDOMIZED CONTROLLED TRIAL
Gabriel López-Velázquez, Minerva Parra-Ortiz, Ignacio De la Mora-De la Mora, Itzhel García-Torres, Sergio Enríquez-Flores, Miguel Angel Alcántara-Ortigoza, Ariadna González-Del Angel, José Velázquez-Aragón, Rosario Ortiz-Hernández, José Manuel Cruz-Rubio, Pablo Villa-Barragán, Carlos Jiménez-Gutiérrez, Pedro Gutiérrez-Castrellón
BACKGROUND: The importance of prebiotics consumption is increasing all over the world due to their beneficial effects on health. Production of better prebiotics from endemic plants raises possibilities to enhance nutritional effects in vulnerable population groups. Fructans derived from Agave Plant have demonstrated their safety and efficacy as prebiotics in animal models. Recently, the safety in humans of two fructans obtained from Agave tequilana (Metlin(®) and Metlos(®)) was demonstrated...
October 29, 2015: Nutrients
https://www.readbyqxmd.com/read/26393118/serum-ferritin-as-a-marker-for-preterm-premature-rupture-of-membranes-a-study-from-a-tertiary-centre-in-central-kerala
#16
Sanoop Adathila Valappil, Miriam Varkey, Binu Areeckal, Krishnadas Thankan, Siva M D
BACKGROUND: Preterm birth is the leading cause of newborn deaths and also the leading cause of death in children under 5 years of age. There is wide spread suspicion that subclinical infection is a common accompaniment and cause of preterm labour. Ferritin is an acute phase reactant and it increases during inflammation.This study aims to determine whether serum ferritin levels which may be raised in the setting of any infective process could be used as a marker of spontaneous preterm labour or PPROM (Preterm premature rupture of membranes)...
July 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26383884/prevalence-of-anemia-and-associations-between-neonatal-iron-status-hepcidin-and-maternal-iron-status-among-neonates-born-to-pregnant-adolescents
#17
Sunmin Lee, Ronnie Guillet, Elizabeth M Cooper, Mark Westerman, Mark Orlando, Tera Kent, Eva Pressman, Kimberly O O'Brien
BACKGROUND: Little is known about anemia and iron status in US newborns because screening for anemia is typically not undertaken until 1 y of age. This study was undertaken to characterize and identify determinants of iron status in newborns born to pregnant adolescents. METHODS: Pregnant adolescents (≤ 18 y, n = 193) were followed from ≥ 12 wk gestation until delivery. Hemoglobin, ferritin, soluble transferrin receptor, serum iron, hepcidin, erythropoietin (EPO), IL-6, and C-reactive protein were assessed in maternal and cord blood...
January 2016: Pediatric Research
https://www.readbyqxmd.com/read/26096619/maternal-iron-deficiency-anemia-as-a-risk-factor-for-the-development-of-retinopathy-of-prematurity
#18
Alper I Dai, Seniz Demiryürek, Sefika Nur Aksoy, Peren Perk, Oguzhan Saygili, Kivanc Güngör
BACKGROUND: Retinopathy of prematurity is a proliferative vascular disease affecting premature newborns and occurs during vessel development and maturation. The aim of this study was to evaluate the maternal iron deficiency anemia as possible risk factors associated with the development of retinopathy of prematurity among premature or very low birth weight infants. METHODS: In this study, mothers of 254 infants with retinopathy of prematurity were analyzed retrospectively, and their laboratory results of medical records during pregnancy were reviewed for possible iron deficiency anemia...
August 2015: Pediatric Neurology
https://www.readbyqxmd.com/read/26090215/effect-of-maternal-cigarette-smoking-on-newborn-iron-stores
#19
Irina B Pateva, Elizabeth H Kerling, Manju Reddy, Dan Chen, Susan E Carlson, Jakica Tancabelic
BACKGROUND: Maternal smoking has been known to have a negative impact on the well being of the developing fetus. Prenatal smoking has been associated with premature births, low birth weight and with certain birth defects. Small research studies have also found a negative correlation between maternal smoking and neonatal body iron. OBJECTIVES: To study and compare the relationship between maternal and infants' body iron in smokers and non-smokers in a large matched-pair cohort...
2015: Clinical Research and Trials
https://www.readbyqxmd.com/read/26087318/comparison-of-three-types-of-intervention-to-enhance-placental-redistribution-in-term-newborns-randomized-control-trial
#20
RANDOMIZED CONTROLLED TRIAL
A K Yadav, A Upadhyay, S Gothwal, K Dubey, U Mandal, C P Yadav
OBJECTIVE: To compare the effect of combined delayed cord clamping and umbilical cord milking to either of them had done alone, on hematological parameters at 6 weeks of age in term neonates. STUDY DESIGN: It was a randomized controlled trial, conducted during January to December 2014. Three hundred eligible neonates were randomly allocated to three parallel groups. Primary outcome was hemoglobin and serum ferritin at 6 weeks of age. Data were analyzed using analysis of variance and Kruskal-Wallis test...
September 2015: Journal of Perinatology: Official Journal of the California Perinatal Association
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