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https://www.readbyqxmd.com/read/28804492/population-genetic-differentiation-and-taxonomy-of-three-closely-related-species-of-saxifraga-saxifragaceae-from-southern-tibet-and-the-hengduan-mountains
#1
Qing-Bo Gao, Yan Li, Zhuo-Ma Gengji, Richard J Gornall, Jiu-Li Wang, Hai-Rui Liu, Liu-Kun Jia, Shi-Long Chen
The effects of rapid, recent uplift of the Hengduan Mountains on evolution and diversification of young floristic lineages still remain unclear. Here, we investigate diversification of three closely related Saxifraga species with a distribution restricted to the Hengduan Mountains (HM) and southern Tibet, and comment on their taxonomy based on molecular evidence. Three chloroplast DNA fragments (rbcL, trnL-F, trnS-G) and the nuclear ribosomal DNA internal transcribed spacer (ITS) were employed to study genetic structure across 104 individuals from 12 populations of Saxifraga umbellulata, S...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28800997/palliative-care-and-human-rights-a-decade-of-evolution-in-standards
#2
Tamar Ezer, Diederik Lohman, Gabriela B de Luca
CONTEXT: Human rights standards to address palliative care have developed over the last decade. OBJECTIVES: This paper aims to examine key milestones in the evolution of human rights standards to address palliative care, relevant advocacy efforts, and areas for further growth. METHODS: The paper provides an analysis of human rights standards in the context of palliative care through the lens of the right to health, freedom from torture and ill treatment, and the rights of older persons and children...
August 8, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28797912/genome-wide-identification-functional-and-evolutionary-analysis-of-terpene-synthases-in-pineapple
#3
Xiaoe Chen, Wei Yang, Liqin Zhang, Xianmiao Wu, Tian Cheng, Guanglin Li
Terpene synthases (TPSs) are vital for the biosynthesis of active terpenoids, which have important physiological, ecological and medicinal value. Although terpenoids have been reported in pineapple (Ananas comosus), genome-wide investigations of the TPS genes responsible for pineapple terpenoid synthesis are still lacking. By integrating pineapple genome and proteome data, twenty-one putative terpene synthase genes were found in pineapple and divided into five subfamilies. Tandem duplication is the cause of TPS gene family duplication...
July 6, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28793089/-evolution-in-the-use-and-the-expenditures-of-a-healthcare-provider
#4
André Luís de Castro Moura Duarte, Felippe de Medeiros Oliveira, Anderson de Andrade Santos, Bento Fortunato Cardoso Dos Santos
Brazil's aging population and the rising number of people reliant upon the country's supplementary healthcare system have elicited the concern of public and private managers regarding the increase in healthcare costs. In this paper, the costs per gender, per type of medical expenses and per age group of a major Brazilian self-managed healthcare provider between 2007 and 2013 were analyzed. This healthcare provider is of interest because, besides portraying a single condition of revenue growth restricted to the existing contributors, it also replicates the demographic profile expected for Brazil in 2050, when approximately one-third of its population will be over 60 years of age...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28790203/the-in-feed-antibiotic-carbadox-induces-phage-gene-transcription-in-the-swine-gut-microbiome
#5
Timothy A Johnson, Torey Looft, Andrew J Severin, Darrell O Bayles, Daniel J Nasko, K Eric Wommack, Adina Howe, Heather K Allen
Carbadox is a quinoxaline-di-N-oxide antibiotic fed to over 40% of young pigs in the United States that has been shown to induce phage DNA transduction in vitro; however, the effects of carbadox on swine microbiome functions are poorly understood. We investigated the in vivo longitudinal effects of carbadox on swine gut microbial gene expression (fecal metatranscriptome) and phage population dynamics (fecal dsDNA viromes). Microbial metagenome, transcriptome, and virome sequences were annotated for taxonomic inference and gene function by using FIGfam (isofunctional homolog sequences) and SEED subsystems databases...
August 8, 2017: MBio
https://www.readbyqxmd.com/read/28776362/acute-heart-failure-and-rhabdomyolysis-a-clue-for-the-diagnosis-of-polymyositis-with-cardiac-involvement
#6
P Pinto-Lopes, L Carneiro-Leão, R Morais, J Pinheiro, A Vieira Lopes, P Bettencourt
Polymyositis is an idiopathic inflammatory myopathy, characterized by proximal muscle weakness and sometimes extramuscular manifestations. We report the case of a 51-year-old male, with history of complete heart block, which required pacemaker implantation, and subsequently heart failure, presenting to the emergency department with worsening of dyspnea and peripheral edema. He was admitted to the Internal Medicine ward with acute heart failure and started on diuretic therapy. During hospitalization, he was discovered to have marked rhabdomyolysis...
August 3, 2017: Reumatismo
https://www.readbyqxmd.com/read/28774303/comparison-of-anti-malarial-drugs-efficacy-in-the-treatment-of-uncomplicated-malaria-in-african-children-and-adults-using-network-meta-analysis
#7
Solange Whegang Youdom, Rachida Tahar, Leonardo K Basco
BACKGROUND: Artemisinin-based combination therapy (ACT) and novel drug combinations are available and used in African countries to treat uncomplicated malaria. Network meta-analysis methods are rarely and poorly applied for the comparison of their efficacies. This method was applied on a set of randomized controlled trials to illustrate its usefulness. METHODS: A literature review available in Pubmed was conducted in July 2016. Eligible studies, conducted in sub-Saharan Africa, published between 2002 and 2016, focused on randomized controlled trials of at least two artemisinin-based combinations to treat uncomplicated malaria in children and adults...
August 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28765454/current-status-of-postdoctoral-and-graduate-programs-in-dentistry
#8
Leon Assael
Advanced dental education has evolved in the context of societal needs and economic trends to its current status. Graduate programs have positioned their role in the context of health systems and health science education trends in hospitals, interprofessional clinical care teams, and dental schools and oral health care systems. Graduate dental education has been a critical factor in developing teams in trauma care, craniofacial disorders, pediatric and adult medicine, and oncology. The misalignment of the mission of graduate dental programs and the demands of private practice has posed a challenge in the evolution of programs as educational programs have been directed towards tertiary and indigent care while the practice community focuses on largely healthy affluent patients for complex clinical interventions...
August 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28765336/new-directions-in-cancer-control-and-population-sciences
#9
Robert A Hiatt
Cancer control science has been evolving since it first became a focus for cancer research and program activities a century ago. The evolution of the field has responded to historical megatrends along the way that keep it relevant to the cancer-related needs of society. This commentary describes some of the key trends and developments now influencing cancer control and population sciences that reflect societal change and new tools and concepts in modern biomedical science. New directions include the impact of climate change, health care delivery research, the growth of population health science, data science, precision medicine, data sharing, implementation science, and new technologies, including social media and new geospatial methodologies...
August 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28763018/maternal-immunization-new-perspectives-on-its-application-against-non-infectious-related-diseases-in-newborns
#10
REVIEW
Federica Riccardo, Aline Réal, Claudia Voena, Roberto Chiarle, Federica Cavallo, Giuseppina Barutello
The continuous evolution in preventive medicine has anointed vaccination a versatile, human-health improving tool, which has led to a steady decline in deaths in the developing world. Maternal immunization represents an incisive step forward for the field of vaccination as it provides protection against various life-threatening diseases in pregnant women and their children. A number of studies to improve prevention rates and expand protection against the largest possible number of infections are still in progress...
August 1, 2017: Vaccines
https://www.readbyqxmd.com/read/28762651/provision-of-pharmaceutical-care-by-community-pharmacists-across-europe-is-it-developing-and-spreading
#11
Filipa A Costa, Claire Scullin, Ghaith Al-Taani, Ahmed F Hawwa, Claire Anderson, Zinaida Bezverhni, Zahida Binakaj, Maria Cordina, Veerle Foulon, Borja Garcia de Bikuña, Han de Gier, Anne Gerd Granås, Olga Grinstova, Nina Griese-Mammen, Jonas Grinceviciene, Svitrigaile Grinceviciene, Susanne Kaae, Loreta Kubiliene, Eduardo L Mariño, Silvia Martins, Pilar Modamio, Giancarlo Nadin, Lotte Stig Nørgaard, Emina Obarcanin, Ivana Tadic, Ljiljana Tasic, James C McElnay, Kurt E Hersberger, Tommy Westerlund
RATIONALE, AIMS, AND OBJECTIVES: Pharmaceutical care involves patient-centred pharmacist activity to improve medicines management by patients. The implementation of this service in a comprehensive manner, however, requires considerable organisation and effort, and indeed, it is often not fully implemented in care settings. The main objective was to assess how pharmaceutical care provision within community pharmacy has evolved over time in Europe. METHOD: A cross-sectional questionnaire-based survey of community pharmacies, using a modified version of the Behavioural Pharmaceutical Care Scale (BPCS) was conducted in late 2012/early 2013 within 16 European countries and compared with an earlier assessment conducted in 2006...
August 1, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28760166/quantifying-network-dynamics-and-information-flow-across-chinese-social-media-during-the-african-ebola-outbreak
#12
Shihui Feng, Liaquat Hossain, John W Crawford, Terry Bossomaier
OBJECTIVE: Social media provides us with a new platform on which to explore how the public responds to disasters and, of particular importance, how they respond to the emergence of infectious diseases such as Ebola. Provided it is appropriately informed, social media offers a potentially powerful means of supporting both early detection and effective containment of communicable diseases, which is essential for improving disaster medicine and public health preparedness. METHODS: The 2014 West African Ebola outbreak is a particularly relevant contemporary case study on account of the large number of annual arrivals from Africa, including Chinese employees engaged in projects in Africa...
August 1, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28759254/emerging-utility-of-virtual-reality-as-a-multidisciplinary-tool-in-clinical-medicine
#13
Ali Pourmand, Steven Davis, Danny Lee, Scott Barber, Neal Sikka
OBJECTIVE: Among the more recent products borne of the evolution of digital technology, virtual reality (VR) is gaining a foothold in clinical medicine as an adjunct to traditional therapies. Early studies suggest a growing role for VR applications in pain management, clinical skills training, cognitive assessment and cognitive therapy, and physical rehabilitation. MATERIALS AND METHODS: To complete a review of the literature, we searched PubMed and MEDLINE databases with the following search terms: "virtual reality," "procedural medicine," "oncology," "physical therapy," and "burn...
July 31, 2017: Games for Health
https://www.readbyqxmd.com/read/28758240/effects-of-imaging-gradients-in-sequences-with-varying-longitudinal-storage-time-case-of-diffusion-exchange-imaging
#14
Samo Lasič, Henrik Lundell, Daniel Topgaard, Tim B Dyrby
PURPOSE: To illustrate the potential bias caused by imaging gradients in correlation MRI sequences using longitudinal magnetization storage (LS) and examine the case of filter exchange imaging (FEXI) yielding maps of the apparent exchange rate (AXR). METHODS: The effects of imaging gradients in FEXI were observed on yeast cells. To analyze the AXR bias, signal evolution was calculated by applying matrix exponential operators. RESULTS: A sharp threshold for the slice thickness was identified, below which the AXR is increasingly underestimated...
July 31, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28757885/the-next-personalized-medicine-evolution-in-orthopedics-how-diagnosing-and-treating-scoliosis-are-about-to-change
#15
EDITORIAL
Alain Moreau
No abstract text is available yet for this article.
March 2017: Personalized Medicine
https://www.readbyqxmd.com/read/28752817/selection-and-transmission-of-antibiotic-resistant-bacteria
#16
Dan I Andersson, Diarmaid Hughes
Ever since antibiotics were introduced into human and veterinary medicine to treat and prevent bacterial infections there has been a steady selection and increase in the frequency of antibiotic resistant bacteria. To be able to reduce the rate of resistance evolution, we need to understand how various biotic and abiotic factors interact to drive the complex processes of resistance emergence and transmission. We describe several of the fundamental factors that underlay resistance evolution, including rates and niches of emergence and persistence of resistant bacteria, time- and space-gradients of various selective agents, and rates and routes of transmission of resistant bacteria between humans, animals and other environments...
July 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28749495/characterization-of-a-highly-efficient-antibiotic-degrading-metallo-%C3%AE-lactamase-obtained-from-an-uncultured-member-of-a-permafrost-community
#17
Marcelo Monteiro Pedroso, Christopher Selleck, Charmaine Enculescu, Jeffrey R Harmer, Nataša Mitić, Whitney R Craig, Waleed Helweh, Philip Hugenholtz, Gene W Tyson, David L Tierney, James A Larrabee, Gerhard Schenk
Antibiotic resistance is a major global health problem, one that threatens to derail the benefits garnered from arguably the greatest success of modern medicine, the discovery of antibiotics. Among the most potent agents contributing to antibiotic resistance are metallo-β-lactamases (MBLs). The discovery of MBL-like enzymes in microorganisms that are not in contact with the human population is of particular concern as these proteins already have the in-built capacity to inactivate antibiotics, even though they may not need MBL activity for their survival...
July 27, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28742251/evolution-of-volatile-emission-in-rhus-coriaria-organs-during-different-stages-of-growth-and-evaluation-of-the-essential-oil-composition
#18
Rose Vanessa Bandeira Reidel, Pier Luigi Cioni, Luigi Majo, Luisa Pistelli
Rhus coriaria, also known as sumac, have been traditionally used in many countries as spice, condiment, dying agent and medicinal herb. The chemical composition of essential oils and the volatile emissions from different organs of this species collected in Sicily (Italy) were analyzed by GC-FID and GC-MS. Monoterpene and sesquiterpene hydrocarbons were the most abundant class in the volatile emissions with β-caryophyllene and α-pinene were the main constituents in the majority of the examined samples. The EO composition was characterized by high amount of monoterpene and sesquiterpene hydrocarbons together with diterpenes...
July 25, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28741222/network-of-anatomical-texts-nanatex-an-open-source-project-for-visualizing-the-interaction-between-anatomical-terms
#19
Ryusuke Momota, Aiji Ohtsuka
Anatomy is the science and art of understanding the structure of the body and its components in relation to the functions of the whole-body system. Medicine is based on a deep understanding of anatomy, but quite a few introductory-level learners are overwhelmed by the sheer amount of anatomical terminology that must be understood, so they regard anatomy as a dull and dense subject. To help them learn anatomical terms in a more contextual way, we started a new open-source project, the Network of Anatomical Texts (NAnaTex), which visualizes relationships of body components by integrating text-based anatomical information using Cytoscape, a network visualization software platform...
July 24, 2017: Anatomical Science International
https://www.readbyqxmd.com/read/28741165/history-and-conceptual-developments-in-vascular-biology-and-angiogenesis-research-a-personal-view
#20
REVIEW
Andreas Bikfalvi
Vascular biology is an important scientific domain that has gradually penetrated many medical and scientific fields. Scientists are most often focused on present problems in their daily scientific work and lack awareness regarding the evolution of their domain throughout history and of how philosophical issues are related to their research field. In this article, I provide a personal view with an attempt to conceptualize vascular development research that articulates lessons taken from history, philosophy, biology and medicine...
July 24, 2017: Angiogenesis
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