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Capillaroscopy

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https://www.readbyqxmd.com/read/28056626/nailfold-capillaroscopic-changes-in-patients-with-systemic-lupus-erythematosus-correlations-with-disease-activity-skin-manifestation-and-nephritis
#1
S Shenavandeh, S Habibi
Introduction The clinical expression of systemic lupus erythematosus (SLE) is the consequence of endothelial cell damage leading to serious multiple organ dysfunction. The aim of this study was to assess the association between nailfold capillaroscopic changes and disease activity, skin and renal involvement in patients with SLE. Methods Demographic variables, clinical manifestations and laboratory data of 108 patients with SLE were investigated. Nailfold capillaroscopy (NFC) was performed in all patients. Result Morphological changes in NFC were observed in 102 out of 108 (94...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28039415/could-nailfold-videocapillaroscopy-usher-in-a-new-era-of-preventative-disease-modifying-therapeutic-intervention-in-systemic-sclerosis-prognostic-value-of-nailfold-capillaroscopy-in-ssc
#2
https://www.readbyqxmd.com/read/28033115/quantification-of-differences-between-nailfold-capillaroscopy-images-with-a-scleroderma-pattern-and-normal-pattern-using-measures-of-geometric-and-algorithmic-complexity
#3
Samuel George Urwin, Bridget Griffiths, John Allen
This study aimed to quantify and investigate differences in the geometric and algorithmic complexity of the microvasculature in nailfold capillaroscopy (NFC) images displaying a scleroderma pattern and those displaying a 'normal' pattern. 11 NFC images were qualitatively classified by a capillary specialist as indicative of 'clear microangiopathy' (CM), i.e. a scleroderma pattern, and 11 as 'not clear microangiopathy' (NCM), i.e. a 'normal' pattern. Pre-processing was performed, and fractal dimension (FD) and Kolmogorov complexity (KC) were calculated following image binarisation...
December 29, 2016: Physiological Measurement
https://www.readbyqxmd.com/read/27996340/geographic-variation-as-a-risk-factor-for-digital-ulcers-in-systemic-sclerosis-patients-a-multicentre-registry
#4
Ejr Souza, C S Muller, Amc Horimoto, R A Rezende, I Guimarães, H A Mariz, A T Dantas, I P Da Costa, Apt Del-Rio, J Sekiyama, C B Kahwage, C Kayser
OBJECTIVE: To evaluate the influence of geographic variation on the risk of digital ulcer (DU) development in systemic sclerosis (SSc) patients. METHODS: This cross-sectional, multicentre study evaluated patients with SSc from centres located in different geographic regions of Brazil (subtropical and tropical climate zones). Demographic and clinical data were collected. RESULTS: The study included 141 patients with SSc (26 from the subtropical and 115 from the tropical zone)...
December 20, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27984835/-phenomenology-and-clinical-relevance-of-the-flammer-syndrome
#5
K Konieczka, J Flammer
The Flammer syndrome (FS) describes the phenotype of people with a predisposition for an altered reaction of the blood vessels to stimuli like coldness, emotional stress or high altitude. Frequent symptoms are: cold hands and/or feet, low blood pressure, prolonged sleep onset time, reduced feeling of thirst, increased sensitivity to odour, pain, vibration and certain drugs. SF subjects are often ambitious and successful but also perfectionistic and sometimes brooding. Frequent signs are: altered gene expression, prolonged blood flow cessation in nailfold capillaroscopy after cold provocation, reduced autoregulation of ocular blood flow, and reduced vasodilation after stimulation with flickering light...
December 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27940590/primary-myocardial-disease-in-scleroderma-a-comprehensive-review-of-the-literature-to-inform-the-uk-systemic-sclerosis-study-group-cardiac-working-group
#6
REVIEW
Lesley-Anne Bissell, Md Yuzaiful Md Yusof, Maya H Buch
Cardiac disease is prevalent in SSc and associated with a poor prognosis. Differentiating primary myocardial disease (SSc-cardiomyopathy) from ischaemic heart disease is difficult and the disease phenotype most at risk is unclear. A comprehensive literature review was performed to inform the UK Systemic Sclerosis Study Group for cardiac disease tasked with producing a best practice pathway for the management of cardiac disease in SSc. This review describes the prevalence of SSc-cardiomyopathy, its associated greater mortality and various manifestations (e...
December 10, 2016: Rheumatology
https://www.readbyqxmd.com/read/27900061/the-diagnostic-value-of-trichoscopy-in-systemic-sclerosis
#7
Małgorzata Kwiatkowska, Adriana Rakowska, Irena Walecka, Lidia Rudnicka
BACKGROUND/OBJECTIVES: Systemic sclerosis is a connective tissue disease, which is characterized by fibrosis of the skin and internal organs, presence of specific antibodies and vascular involvement. Capillaroscopy is a useful method for the diagnosis and follow-up of patients with systemic sclerosis. Trichoscopy is a rapid, non-invasive technique, which has become a standard procedure in differential diagnosis of scalp and hair diseases. The aim of this study was to assess whether trichoscopy may be applied in imaging microvessels in patients with systemic sclerosis...
November 13, 2016: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/27888176/nailfold-capillary-morphological-characteristics-of-hand-arm-vibration-syndrome-a-cross-sectional-study
#8
QingSong Chen, GuiPing Chen, Bin Xiao, HanSheng Lin, HongYing Qu, DanYing Zhang, MaoGong Shi, Li Lang, Bei Yang, MaoSheng Yan
OBJECTIVE: The purpose of this study was to investigate the characteristics of nailfold capillaroscopy associated with hand-arm vibration syndrome (HAVS). METHODS: In total, 113 male gold miners were recruited: 35 workers who were chronically exposed to vibration and developed vibration-induced white finger were defined as the HAVS group, 39 workers who were exposed to vibration but did not have HAVS were classified as the vibration-exposed controls (VEC) group, and 39 workers without vibration exposure were categorised as the non-VEC (NVEC) group...
November 25, 2016: BMJ Open
https://www.readbyqxmd.com/read/27871347/dermatomyositis-part-2-diagnosis-association-with-malignancy-and-treatment
#9
REVIEW
Marcia Ramos-E-Silva, Ana Paula Frade Lima Pinto, Rodrigo Pirmez, Tullia Cuzzi, Sueli Carneiro
In this second part of the series on dermatomyositis, the diagnosis and its criteria with review of autoantibodies, capillaroscopy, imaging exams, histopathology, muscle biopsy, electroneuromyography, and muscular enzymes will be assessed. The association with malignancy, since it is described as paraneoplasic, will be discussed. The different therapeutic options for this disease will also be reported, including for dystrophic calcification, a rare and late complication of dermatomyositis.
2016: Skinmed
https://www.readbyqxmd.com/read/27828654/nailfold-capillaroscopy-in-leprosy
#10
Adma Silva de Lima, Vanessa Irusta Dal Pizzol, Scheila Fritsch, Gabriela Poglia Fonseca, Fabiane Andrade Mulinari-Brenner, Carolina de Souza Muller, Vanessa Cristhine Dalombo Ottoboni
Due to mounting evidences of interaction between Hansen's bacilli with endothelial cells and the paucity of studies addressing the presence of nailfold capillaroscopic alterations in patients with Hansen's disease, a study was carried out in order to verify the presence of capillaroscopic alterations in patients with leprosy in its various forms and its correlation with clinical parameters. Ten patients were evaluated at a specialized university service. Sixty percent of those had some capillaroscopic change, such as micro-hemorrhages, ectatic, bushy and corkscrew capillaries...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27751625/paraneoplastic-systemic-sclerosis-about-3-cases-and-review-of-literature
#11
J-B Monfort, I Lazareth, P Priollet
OBJECTIVE: Association between cancer and systemic sclerosis (SSc) has been described. However, paraneoplastic SSc is not well known. The aim of this article is to describe cases of paraneoplastic systemic sclerosis and to compare them to other cases of the literature, to find characteristics that can make suspect a paraneoplastic mechanism when SSc is diagnosed. METHODS: We retrospectively analyzed patients, in our department who, over the last 15 years, presented with Raynaud's phenomenon with a diagnosis of SSc (including cancer during the period of SSc)...
December 2016: Journal des Maladies Vasculaires
https://www.readbyqxmd.com/read/27614146/capillary-density-an-important-parameter-in-nailfold-capillaroscopy
#12
REVIEW
Zahra Emrani, Abdolamir Karbalaie, Alimohammad Fatemi, Mahnaz Etehadtavakol, Björn-Erik Erlandsson
Nailfold capillaroscopy is one of the various noninvasive bioengineering methods used to investigate skin microcirculation. It is an effective examination for assessing microvascular changes in the peripheral circulation; hence it has a significant role for the diagnosis of Systemic sclerosis with the classic changes of giant capillaries as well as the decline in capillary density with capillary dropout. The decline in capillary density is one of microangiopathic features existing in connective tissue disease...
January 2017: Microvascular Research
https://www.readbyqxmd.com/read/27594391/nailfold-capillaroscopy-microscopy-an-interdisciplinary-appraisal
#13
Peter Franz Klein-Weigel, Cord Sunderkötter, Oliver Sander
Nailfold capillaroscopy is a method of great diagnostic value in the differential diagnosis of primary versus secondary Raynaud´s phenomenon, of systemic sclerosis versus other so called connective tissue diseases and of additional diagnostic value in other entities. Rheumatologists, dermatologists, and angiologists in Germany have convened in an interdisciplinary working group in which they synergistically combined their expertise to develop a common nomenclature and standards for the technical performance of nailfold capillary microscopy...
September 2016: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27552783/the-place-of-nailfold-capillaroscopy-among-instrumental-methods-for-assessment-of-some-peripheral-ischaemic-syndromes-in-rheumatology
#14
REVIEW
Sevdalina N Lambova
Micro- and macrovascular pathology is a frequent finding in a number of common rheumatic diseases. Secondary Raynaud's phenomenon (RP) is among the most common symptoms in systemic sclerosis and several other systemic autoimmune diseases including a broad differential diagnosis. It should be also differential from other peripheral vascular syndromes such as embolism, thrombosis, etc., some of which lead to clinical manifestation of the blue toe syndrome. The current review discusses the instrumental methods for vascular assessments...
April 2016: Folia Medica
https://www.readbyqxmd.com/read/27526772/absence-of-scleroderma-pattern-at-nail-fold-capillaroscopy-valuable-in-the-exclusion-of-scleroderma-in-unselected-patients-with-raynaud-s-phenomenon
#15
Lesley-Anne Bissell, Giuseppina Abignano, Paul Emery, Francesco Del Galdo, Maya H Buch
BACKGROUND: To report the predictive value of nail-fold capillaroscopy (NFC) patterns of vasculopathy for systemic sclerosis (Scleroderma; SSc) in an unselected cohort of patients with Raynaud's phenomenon (RP). METHODS: Patients referred to a tertiary SSc clinic with RP were evaluated by light/video-NFC. Clinical diagnosis, details and serology were recorded. Primary RP was defined as RP with no features of connective tissue disease (CTD)/antibody. NFC patterns were determined: normal, non-specific, 'early', 'active' or 'late' SSc patterns...
2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27494080/raynaud-s-syndrome-in-children-systematic-review-and-development-of-recommendations-for-assessment-and-monitoring
#16
Clare E Pain, Tamás Constantin, Natasa Toplak, Monica Moll, Christof Iking-Konert, Daniella P Piotto, Nuray Aktay Ayaz, Dana Nemcova, Peter H Hoeger, Maurizio Cutolo, Vanessa Smith, Ivan Foeldvari
OBJECTIVES: To develop recommendations for investigation and monitoring of children with Raynaud's syndrome, based on paediatric evidence collated by a systematic review. METHODS: A systematic review was undertaken to establish the paediatric evidence for assessment and monitoring of Raynaud's syndrome. An expert panel including members of the Paediatric Rheumatology European Society (PRES) Scleroderma Working Group, were invited to a consensus meeting where recommendations were developed based on evidence graded by the systematic review and where evidence was lacking, consensus opinion...
September 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27476627/low-vitamin-d-serum-levels-in-diffuse-systemic-sclerosis-a-correlation-with-worst-quality-of-life-and-severe-capillaroscopic-findings
#17
Marília M Sampaio-Barros, Liliam Takayama, Percival D Sampaio-Barros, Eloísa Bonfá, Rosa Maria R Pereira
OBJECTIVE: The aim of this study was to analyze the correlation of vitamin D levels with clinical parameters, bone mineral density (BMD), quality of life (QoL) and nailfold capillaroscopy (NC) in patients with diffuse systemic sclerosis (SSc). METHODS: Thirty-eight female patients with diffuse SSc were analyzed regarding 25-hydroxyvitamin D (25OHD) serum levels. At inclusion, organ involvement, autoantibodies, modified Rodnan skin score (mRSS), Medsger Disease Severity Index (MDSI), body mass index (BMI), BMD, NC, Short-Form-36 Questionnaire (SF-36), and Health Assessment Questionnaire (HAQ), were performed through a standardized interview, physical examination and electronic chart review...
July 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27437101/delivering-a-one-stop-integrated-and-patient-centered-service-for-patients-with-rheumatic-diseases
#18
Paula Väre, Elena Nikiphorou, Pekka Hannonen, Tuulikki Sokka
OBJECTIVE: To describe a one-stop, integrated rheumatology service and assess patient satisfaction. METHODS: A descriptive report and patient satisfaction survey of a rheumatology clinic model first developed in 1996 to enhance the patient "journey" through rheumatology services. A patient-satisfaction survey over a 3-week period assessed several aspects of care including quality of services, consultations, and patient education. RESULTS: All referrals are screened by a rheumatologist to pre-schedule laboratory/radiology/other tests for the visit...
2016: SAGE Open Medicine
https://www.readbyqxmd.com/read/27421220/raynaud-s-phenomenon
#19
REVIEW
Michael Hughes, Ariane L Herrick
Raynaud's phenomenon (RP) is a major cause of pain and disability in patients with autoimmune connective tissue diseases (CTDs), particularly systemic sclerosis (SSc). The clinician must perform a comprehensive clinical assessment in patients with RP to differentiate between primary (idiopathic) and secondary RP, in particular (for rheumatologists), secondary to an autoimmune CTD, as both the prognosis and treatment may differ significantly. Key investigations are nailfold capillaroscopy and testing for autoantibodies (in particular, those associated with SSc)...
February 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27407282/capillaroscopy-a-role-in-modern-rheumatology
#20
REVIEW
Marek M Chojnowski, Anna Felis-Giemza, Marzena Olesińska
Capillaroscopy is a non-invasive, easy and safe diagnostic technique designed to evaluate small vessels of the microcirculation in the nailfold. It can reveal both the general architecture of capillary rows and fine details of particular vessels. The most important indications for performing capillaroscopy include differential diagnosis of primary and secondary Raynaud's phenomenon, as well as assessment of scleroderma spectrum disorders. In systemic sclerosis capillary abnormalities appear and evolve in a clearly defined sequence called the scleroderma pattern, which correlates with internal organ involvement...
2016: Reumatologia
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