keyword
MENU ▼
Read by QxMD icon Read
search

Capillaroscopy

keyword
https://www.readbyqxmd.com/read/29734516/dermal-capillary-rarefaction-as-a-marker-of-microvascular-damage-in-patients-with-rheumatoid-arthritis-association-with-inflammation-and-disorders-of-the-macrocirculation
#1
Panagiota Anyfanti, Eugenia Gkaliagkousi, Areti Triantafyllou, Xenophon Zabulis, Panagiotis Dolgyras, Vasiliki Galanopoulou, Spyros Aslanidis, Stella Douma
OBJECTIVE: Capillary rarefaction is observed in various cardiovascular diseases, yet it remains understudied in RA, a chronic inflammatory disease accompanied by excess cardiovascular risk. We quantified capillary density in RA patients and explored potential associations with macrocirculatory disorders, inflammation and cardiovascular risk. METHODS: Dermal capillary density was assessed with nailfold capillaroscopy in RA and non-RA individuals, using specifically designed semiautomated software...
May 7, 2018: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/29699986/resting-nailfold-capillary-blood-flow-in-primary-open-angle-glaucoma
#2
Clara C Cousins, Jonathan C Chou, Scott H Greenstein, Stacey C Brauner, Lucy Q Shen, Angela V Turalba, Patricia Houlihan, Robert Ritch, Janey L Wiggs, Paul A Knepper, Louis R Pasquale
BACKGROUND/AIMS: An altered haemodynamic profile for various ocular posterior segment capillary beds has been documented in primary open-angle glaucoma (POAG). POAG may also involve abnormal non-ocular blood flow, and the nailfold capillaries, which are not affected by elevated intraocular pressure (IOP), are readily assessable. METHODS: We measured resting nailfold capillary blood flow in 67 POAG and 63 control subjects using video capillaroscopy. Masked readers tracked blood column voids between consecutive, registered image sequence frames, measured vessel diameter and calculated blood flow...
April 26, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29688190/-present-day-possibilities-of-non-invasive-control-over-microcirculation-and-metabolism-in-man
#3
A A Fedorovich, A G Bagdasarian, I G Uchkin, G N Soboleva, S A Boĭtsov
The main function of the microcirculatory bed consists in maintaining tissue homeostasis at an optimal level irrespective of the effect of various external and internal factors. Of all types of metabolism (diffusive, filtration-reabsorption and vesicular), directly dependent on the haemodynamic parameters is filtration-reabsorption metabolism which provides exchange of water, low-molecular-weight and water-soluble substances at the opposite to the heart «pole» of the cardiovascular system. The present study was aimed at testing a hypothesis that activation of metabolic processes in man would be accompanied by alterations in haemodynamic parameters which may be registered by means of modern non-invasive methods of examination, i...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29665800/mda-5-associated-rapidly-progressive-interstitial-lung-disease-with-recurrent-pneumothoraces-a-case-report
#4
Safi Alqatari, Peter Riddell, Sinead Harney, Michael Henry, Grainne Murphy
BACKGROUND: Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific antibodies could be negative, but with high clinical suspicion, myositis associated antibodies should be ordered. Anti-MDA-5 antibodies was reported in literature to be associated with severe and rapidly progressive interstitial lung disease, with few case reports of pneumothorax and/or pneumomediastinum...
April 17, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29614967/cardiovascular-outcomes-of-nephrotic-syndrome-in-childhood-cvons-study-a-protocol-for-prospective-cohort-study
#5
S K Patnaik, P Kumar, M Bamal, S Patel, M P Yadav, V Kumar, A Sinha, A Bagga, M Kanitkar
BACKGROUND: Nephrotic syndrome (NS) is characterized by dyslipidemia which is a well-known risk factor for atherogenesis. Atherosclerosis in childhood is mostly subclinical and endothelial dysfunction is known to precede this. Evidence for screening for endothelial dysfunction and cardiovascular risk factors and early identification of premature onset of atherosclerosis in childhood NS remains tenuous in the absence of well-designed prospective studies addressing cardiovascular comorbidity in NS...
April 3, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29608790/increase-in-perfused-boundary-region-of-endothelial-glycocalyx-is-associated-with-higher-prevalence-of-ischemic-heart-disease-and-lesions-of-microcirculation-and-vascular-wall
#6
Alexander Y Gorshkov, Marina V Klimushina, Sergei A Boytsov, Alexander Y Kots, Nadezhda G Gumanova
OBJECTIVE: Perfused boundary region (PBR) characterizes penetration of red blood cells inside glycocalyx and its thickness can have profound impact on microcirculation and other vascular parameters. The goal of our study was to reliably quantify PBR and assess its potential use as a new marker of cardiovascular pathology. METHODS: The study included 208 patients (123 men and 85 women from 40 to 65 years of age) with various grades of cardiovascular SCORE risk index and ischemic heart disease...
April 2, 2018: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/29605552/automated-structure-and-flow-measurement-a-promising-tool-in-nailfold-capillaroscopy
#7
Michael Berks, Graham Dinsdale, Andrea Murray, Tonia Moore, Joanne Manning, Chris Taylor, Ariane L Herrick
OBJECTIVES: Despite increasing interest in nailfold capillaroscopy, objective measures of capillary structure and blood flow have been little studied. We aimed to test the hypothesis that structural measurements, capillary flow, and a combined measure have the predictive power to separate patients with systemic sclerosis (SSc) from those with primary Raynaud's phenomenon (PRP) and healthy controls (HC). METHODS: 50 patients with SSc, 12 with PRP, and 50 HC were imaged using a novel capillaroscopy system that generates high-quality nailfold images and provides fully-automated measurements of capillary structure and blood flow (capillary density, mean width, maximum width, shape score, derangement and mean flow velocity)...
March 29, 2018: Microvascular Research
https://www.readbyqxmd.com/read/29602558/does-nailfold-capillaroscopy-help-predict-future-outcomes-in-systemic-sclerosis-a-systematic-literature-review
#8
REVIEW
Dolcie Paxton, John D Pauling
BACKGROUND: Nailfold capillaroscopy (NC) is an important diagnostic tool in systemic sclerosis (SSc). Confirmation of NC as a prognostic factor could facilitate earlier intervention and slow disease progression in SSc. We undertook a systematic literature review to evaluate the prognostic value of NC in predicting SSc disease progression. METHODS: Standardised searches of EMBASE and MEDLINE were undertaken to identify longitudinal studies of adult subjects with SSc reporting the prognostic value of NC for any aspect of disease progression and/or survival...
February 14, 2018: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29595279/-systemic-sclerosis-in-2017
#9
Tomáš Soukup, Tomáš Veleta
Systemic sclerosis is classed as a diffuse (systemic) disease of connective tissue. It is a heterogeneous disease significantly shortening life expectancy. Its etiology is unknown. Pathogenetic interplay is assumed to involve a triad of pathological autoimmune inflammation, vasculopathy and fibrosis. Clinical manifestations can be classed based on the preponderant pathogenetic process. Vasculopathy is manifested by secondary Raynauds phenomenon with abnormal findings on the nailfold capillaroscopy, skin telangiectasias, gastric antral vascular ectasia, life threatening scleroderma renal crisis, digital ulcerations and prognostically severe pulmonary arterial hypertension...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29578964/comparison-between-invasive-and-noninvasive-techniques-of-evaluation-of-microvascular-structural-alterations
#10
Carolina De Ciuceis, Claudia Agabiti Rosei, Stefano Caletti, Valentina Trapletti, Maria A Coschignano, Guido A M Tiberio, Sarah Duse, Franco Docchio, Simone Pasinetti, Federica Zambonardi, Francesco Semeraro, Enzo Porteri, Leonardo Solaini, Giovanna Sansoni, Paola Pileri, Claudia Rossini, Francesco Mittempergher, Nazario Portolani, Silvia Ministrini, Enrico Agabiti-Rosei, Damiano Rizzoni
BACKGROUND: The evaluation of the morphological characteristics of small resistance arteries in humans is challenging. The gold standard method is generally considered to be the measurement by wire or pressure micromyography of the media-to-lumen ratio of subcutaneous small vessels obtained by local biopsies. However, noninvasive techniques for the evaluation of retinal arterioles were recently proposed; in particular, two approaches, scanning laser Doppler flowmetry (SLDF) and adaptive optics, seem to provide useful information; both of them provide an estimation of the wall-to-lumen ratio (WLR) of retinal arterioles...
May 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29560093/capillary-density-has-no-value-as-an-early-biomarker-of-bevacizumab-efficacy-in-metastatic-colorectal-cancers-a-prospective-clinical-trial
#11
Jean-David Fumet, Aurélie Bertaut, Leila Bengrine, Patricia Lapierre, Julie Vincent, François Ghiringhelli, Nicolas Falvo
Background: Bevacizumab is a recombinant humanized monoclonal immunoglobulin G1 antibody targeting VEGF-A. It is currently used with chemotherapy as the first- or second-line therapy in metastatic colorectal cancer. Previous studies have showed that anti-angiogenic agents decrease capillary density. We evaluated the link between decreased capillary density and the response to bevacizumab-based chemotherapy. Results: Overall, 43 patients with metastatic colorectal cancer treated with first-line bevacizumab-based chemotherapy were enrolled...
February 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29558359/-mondor-s-disease-or-systemic-sclerosis-diagnostic-and-therapeutic-dilemmas
#12
Olga Kostrzewa, Paweł Kołodziej, Maria Majdan, Robert Zwolak, Anna Górak, Krzysztof Bar
In this article we have presented a case of 31-year-old male with thickening of the skin and tender cord of superficial veins of the penis and laboratory findings of the high titer of PM/Scl-100 antibodies in the serum. The patient was referred to the Rheumatology Department due to suspected systemic sclerosis. The HRCT scan of his lungs revealed fibrous degeneration and ground-glass opacity in the lower lobes. Capillaroscopy showed abnormalities, which were not typical for systemic sclerosis. In Doppler ultrasound examination of penis, superficial dorsal and circumflex veins thrombosis and inflammatory infiltration were observed...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29558039/analysis-of-peripheral-nerve-and-autonomic-nervous-system-function-and-the-stage-of-microangiopathy-in-patients-with-secondary-raynaud-s-phenomenon-in-the-course-of-connective-tissue-diseases
#13
Izabela Gosk-Bierska, Maria Misterska-Skóra, Marta Wasilewska, Małgorzata Bilińska, Jerzy Gosk, Rajmund Adamiec, Magdalena Koszewicz
BACKGROUND: The pathogenesis of secondary Raynaud's phenomenon (SRP) associated with connective tissue diseases (CTD) is not entirely understood. Nervous system dysfunction and microangiopathy are considered to be causes of this pathology. OBJECTIVES: Peripheral and autonomic nervous system function, the stage of microangiopathy, and the relationships between these in patients with SRP were analyzed. MATERIAL AND METHODS: In the study, 20 patients with CTD-related SRP and 30 healthy controls were subject to capillaroscopy, standard conduction velocity tests and conduction velocity distribution (CVD) tests in ulnar and peroneal nerves, heart rate variability (HRV), and sympathetic skin response (SSR) tests...
March 20, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29544760/the-emerging-application-of-semi-quantitative-and-quantitative-capillaroscopy-in-systemic-sclerosis
#14
REVIEW
Carina Mihai, Vanessa Smith, Rucsandra Dobrota, Ana Maria Gheorghiu, Maurizio Cutolo, Oliver Distler
Systemic sclerosis (SSc) is a connective tissue disease with high morbidity and mortality, characterized by autoimmunity, obliterative vasculopathy involving mainly the microvasculature, and fibrosis. SSc-specific nailfold capillaroscopic changes have been defined, and nailfold capillaroscopy (NFC) is now unequivocally accepted to be a cornerstone for the early diagnosis of SSc. However, the use of NFC in patients already diagnosed with SSc is still not standardized. Several studies have shown that NFC abnormalities correlate with disease activity and severity and are predictive for disease worsening, such as occurrence of new digital ulcers...
July 2018: Microvascular Research
https://www.readbyqxmd.com/read/29526628/the-role-of-capillaroscopy-and-thermography-in-the-assessment-and-management-of-raynaud-s-phenomenon
#15
REVIEW
Ariane L Herrick, Andrea Murray
Most patients with Raynaud's phenomenon (RP) have "benign" primary RP (PRP), but a minority have an underlying cause, for example a connective tissue disease such as systemic sclerosis (SSc). Secondary RP can be associated with structural as well as functional digital vascular changes and can be very severe, potentially progressing to digital ulceration or gangrene. The first step in management is to establish why the patient has RP. This short review discusses the role of nailfold capillaroscopy and thermography in the assessment of RP...
May 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29512213/the-role-of-the-dermatologist-in-raynaud-s-phenomenon-a-clinical-challenge
#16
REVIEW
C Matucci-Cerinic, V Nagaraja, F Prignano, B Kahaleh, S Bellando-Randone
Raynaud's phenomenon (RP) is a functional vascular disorder involving extremities. In his practice, the dermatologist may frequently encounter RP which affects mainly women and is categorized into a primary benign form and a secondary form associated with different diseases (infections, drugs, autoimmune and vascular conditions, haematologic, rheumatologic and endocrinologic disorders). Still today, the differential diagnosis is a clinical challenge. Therefore, a careful history and a physical examination, together with laboratory tests and nailfold capillaroscopy, is mandatory...
March 6, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29506240/longitudinal-nailfold-capillaroscopy-tracking-of-microangiopathic-changes-in-systemic-sclerosis
#17
Graham Dinsdale, Anniek M van Roon, Andrea Murray, Christopher Taylor, Ariane L Herrick
No abstract text is available yet for this article.
February 28, 2018: Rheumatology
https://www.readbyqxmd.com/read/29501536/evaluation-of-microvascular-endothelial-function-and-capillary-density-in-patients-with-infective-endocarditis-using-laser-speckle-contrast-imaging-and-video-capillaroscopy
#18
Amanda Barcelos, Eduardo Tibirica, Cristiane Lamas
OBJECTIVE: To evaluate the systemic microcirculation of patients with infective endocarditis (IE). METHODS: This is a comparative study of patients with definite IE by the modified Duke criteria admitted to our center for treatment. A reference group of sex- and age-matched healthy volunteers was included. Microvascular flow was evaluated in the forearm using a laser speckle contrast imaging system, for noninvasive measurement of cutaneous microvascular perfusion, in combination with skin iontophoresis of acetylcholine (ACh) and sodium nitroprusside (SNP) to test microvascular reactivity...
July 2018: Microvascular Research
https://www.readbyqxmd.com/read/29476351/can-nailfold-videocapillaroscopy-images-be-interpreted-reliably-by-different-observers-results-of-an-inter-reader-and-intra-reader-exercise-among-rheumatologists-with-different-experience-in-this-field
#19
Tatiana Sofía Rodriguez-Reyna, Chiara Bertolazzi, Angélica Vargas-Guerrero, Marwin Gutiérrez, Gabriela Hernández-Molina, Marcelo Audisio, Susana Roverano, Margarita González de Urizar, José Francisco Díaz Coto, Blanca Elizabeth Herrera Velasco, Mijahil Pavel Cornejo Ortega, Ana María Sapag Durán, Janeth Edelina Villegas Guzmán, Luís Fernando Medina Quintero, Mirtha Sabelli, Sandy Sapag Durán, Maurizio Cutolo
Nailfold videocapillaroscopy (VCP) allows non-invasive assessment of the microcirculation. Adequate training in this field is relevant for rheumatologists. There is increasing evidence of the reliability of VCP findings among different readers. OBJECTIVE: To evaluate inter- and intra-reader agreement of rheumatologists to identify normal images and systemic sclerosis (SSc) patterns on VCP ("early," "active," and "late" proposed by Cutolo et al.). Thirteen rheumatologists with different experience in nailfold VCP received training to standardize reading criteria...
February 23, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29455200/cardiovascular-and-patient-phenotype-of-extended-haemodialysis-a-critical-analysis-of-studying-a-unique-patient-population
#20
Nicos Mitsides, Tom Cornelis, Natascha J H Broers, Nanda M P Diederen, Paul Brenchley, Frank M van der Sande, Casper Schalkwijk, Jeroen P Kooman, Sandip Mitra
BACKGROUND: Extended haemodialysis (EHD) has been associated with better outcomes compared to conventional (CHD) regimes. The cardiovascular (CV) profile of these patients has not been assessed in detail. METHODS: We report baseline demographic and CV phenotype of 36 CHD and 36 EHD participants to a longitudinal multicentre study. We measured pulse wave velocity (PWV), 24-h ambulatory blood pressure, sublingual dark-field capillaroscopy and vascular biomarkers. RESULTS: EHD patients were younger (p < 0...
2018: Blood Purification
keyword
keyword
54077
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"