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https://www.readbyqxmd.com/read/28206756/effect-of-bioprocessing-on-the-in-vitro-colonic-microbial-metabolism-of-phenolic-acids-from-rye-bran-fortified-breads
#1
Ville Mikael Koistinen, Emilia Nordlund, Kati Katina, Ismo Mattila, Kaisa Poutanen, Kati Hanhineva, Anna-Marja Aura
Cereal bran is an important source of dietary fiber and bioactive compounds, such as phenolic acids. We aimed to study the phenolic acid metabolism of native and bioprocessed rye bran fortified refined wheat bread and to elucidate the microbial metabolic route of phenolic acids. After incubation in an in vitro colon model, the metabolites were analyzed using two different methods applying mass spectrometry. While phenolic acids were released more extensively from the bioprocessed bran bread and ferulic acid had consistently higher concentrations in the bread type during fermentation, there were only minor differences in the appearance of microbial metabolites, including the diminished levels of certain phenylacetic acids in the bioprocessed bran...
February 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28193824/correction-to-eco-evolutionary-dynamics-in-urbanized-landscapes-evolution-species-sorting-and-the-change-in-zooplankton-body-size-along-urbanization-gradients
#2
Kristien I Brans, Lynn Govaert, Jessie M T Engelen, Andros T Gianuca, Caroline Souffreau, Luc De Meester
No abstract text is available yet for this article.
April 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28193436/use-of-bran-fractions-and-debranned-kernels-for-the-development-of-pasta-with-high-nutritional-and-healthy-potential
#3
Roberto Ciccoritti, Federica Taddei, Isabella Nicoletti, Laura Gazza, Danilo Corradini, Maria Grazia D'Egidio, Daniela Martini
The quality of pasta produced with debranning products (bran fractions, BF, and debranned kernels, DK) of durum wheat was investigated by evaluating their total antioxidant capacity, occurrence of nutritional and bioactive compounds, and sensory properties. Two pasta samples, produced with BF-enriched semolina (BF pasta) or only with micronized DK (DK pasta), respectively, were compared with pasta made with traditional semolina (control pasta). BF pasta and DK pasta displayed significantly higher content of bioactive compounds, such as phenolic compounds and dietary fibre, than control pasta, to a different extent for the diverse compounds...
June 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28180212/kodo-millet-whole-grain-and-bran-supplementation-prevents-high-fat-diet-induced-derangements-in-a-lipid-profile-inflammatory-status-and-gut-bacteria-in-mice
#4
Siddhartha M Sarma, Pragyanshu Khare, Sneha Jagtap, Dhirendra P Singh, Ritesh K Baboota, Koteswaraiah Podili, Ravneet K Boparai, Jaspreet Kaur, Kamlesh K Bhutani, Mahendra Bishnoi, Kanthi Kiran Kondepudi
The protective role of kodo millet whole grain and bran supplementation in diet induced obesity has not been investigated. Here we have studied the role of kodo millet supplementation in age matched Swiss albino mice that were randomly divided into groups and fed their respective diets for 16 weeks. A high fat diet increased weight gain, reduced glucose tolerance, increased serum lipids, altered hepatic and adipocyte gene expression and caused dysbiosis in the intestinal beneficial bacteria. Kodo millet supplementation did not affect weight gain but it improved glucose tolerance and prevented an increase in the serum cholesterol and lipid parameters (P ≤ 0...
February 9, 2017: Food & Function
https://www.readbyqxmd.com/read/28167418/evaluation-of-in-silico-pharmacokinetic-properties-and-in-vitro-cytotoxic-activity-of-selected-newly-synthesized-n-succinimide-derivatives
#5
Natasa P Milosevic, Vesna Kojic, Jelena Curcic, Dimitar Jakimov, Natasa Milic, Nebojsa Banjac, Gordana Uscumlic, Roman Kaliszan
Design of a new drug entity is usually preceded by analysis of quantitative structure activity (properties) relationships, QSA(P)R. Six newly synthesized succinimide derivatives have been determined for (i) in silico physico-chemical descriptors, pharmacokinetic and toxicity predictors, (ii) in vitro biological activity on four different carcinoma cell lines and on normal fetal lung cells and (iii) lipophilicity on liquid chromatography. All compounds observed were predicted for good permeability and solubility, good oral absorption rate and moderate volume of distribution as well as for modest blood brain permeation, followed by acceptable observed toxicity...
January 29, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28165414/deoxynivalenol-exposure-in-norway-risk-assessments-for-different-human-age-groups
#6
REVIEW
Leif Sundheim, Inger Therese Lillegaard, Christiane Kruse Fæste, Anne-Lise Brantsæter, Guro Brodal, Gunnar Sundstøl Eriksen
Deoxynivalenol (DON) is the most common mycotoxin in Norwegian cereals, and DON is detected in most samples of crude cereal grain and cereal food commodities such as flour, bran, and oat flakes. The Norwegian Scientific Committee for Food Safety assessed the risk for adverse effects of deoxynivalenol (DON) in different age groups of the domestic population. This review presents the main results from the risk assessment, supplemented with some recently published data. Impairment of the immune system together with reduced feed intake and weight gain are the critical effects of DON in experimental animals on which the current tolerable daily intake was established...
February 4, 2017: Toxins
https://www.readbyqxmd.com/read/28161736/dietary-fibres-modulate-the-composition-and-activity-of-butyrate-producing-bacteria-in-the-large-intestine-of-suckling-piglets
#7
Chunlong Mu, Lingli Zhang, Xiangyu He, Hauke Smidt, Weiyun Zhu
Dietary fibres have been shown to affect early-life microbiota colonization in the large intestine of suckling piglets, however, much less is known as to whether they also modulate the composition and activity of butyrate-producing bacteria. Here, we investigated the effect of dietary fibres on the abundance, composition, and activity of butyrate-producing bacteria in suckling piglets. Piglets were fed a control diet or creep feeds containing alfalfa, wheat bran, or pure cellulose, respectively, from postnatal day 7 to 22...
February 4, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28159727/a-p-coumaroyl-esterase-from-rhizoctonia-solani-with-a-pronounced-chlorogenic-acid-esterase-activity
#8
Annabel Nieter, Sebastian Kelle, Diana Linke, Ralf G Berger
Extracellular esterase activity was detected in submerged cultures of Rhizoctonia solani grown in the presence of sugar beet pectin or Tween 80. Putative type B feruloyl esterase (FAE) coding sequences found in the genome data of the basidiomycete were heterologously expressed in Pichia pastoris. Recombinant enzyme production on the 5-L bioreactor scale (RspCAE: 3245UL(-1)) exceeded the productivity of the wild type strain by a factor of 800. Based on substrate specificity profiling, the purified recombinant RspCAE was classified as a p-coumaroyl esterase (pCAE) with a pronounced chlorogenic acid esterase side activity...
January 31, 2017: New Biotechnology
https://www.readbyqxmd.com/read/28155258/phytochemicals-in-whole-grain-wheat-and-their-health-promoting-effects
#9
Yingdong Zhu, Shengmin Sang
Accumulated evidence in epidemiological studies has consistently shown that consumption of whole grains is inversely associated with risk of major chronic diseases such as certain types of cancer, type 2 diabetes, and cardiovascular diseases. Dietary fiber has been reported to be responsible for the health effects of whole grain consumption. Evidence from in vitro and in vivo studies is emerging that, in addition to dietary fiber and minerals, the unique phytochemicals in whole grains may in part contribute to these health-promoting effects...
February 3, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28155168/expression-and-characteristics-of-an-endoglucanase-from-trichoderma-atroviride-taegii-in-saccharomyces-cerevisiae
#10
Xiao-Mei Huang, Qing-Qing Li, Xiu-Ling Chen, Jin-Xia Fan, Xiu-Hong Xu, Xu-Dong Sun, Dong-Yu Li, Hong-Xiao Zhao
Endoglucanase secreted by the fungus Trichoderma atroviride is a kind of cellulase. An endoglucanase gene egII was cloned from T. atroviride AS3.3013 and expressed in Saccharomyces cerevisiae INVScI. The open reading frame of the egII gene was composed of 1257 bp, encoding 418 amino acids with a molecular weight of 44.23 kDa plus a signal peptide of 21 amino acids. Based on sequence similarity, TaEGII belonged to the glycosyl hydrolase family 5. Expression of the egII gene in T. atroviride AS3.3013 can be induced by microcrystalline cellulose (MCC), bran, carboxymethyl cellulose (CMC), rice straw, and corn stalk but is inhibited by glucose...
February 2, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28142333/identification-of-the-active-protein-in-rice-bran-protein-having-an-inhibitory-activity-of-cholesterol-micellar-solubility
#11
Jilite Wang, Masaya Shimada, Satoshi Nagaoka
In our previous study, rice bran protein (RBP) inhibited cholesterol micellar solubility in vitro and decreased serum cholesterol level in rats. In the present study, RBP was separated and purified by size-exclusion chromatography and reversed-phase chromatography. The active protein of RBP related to cholesterol micellar solubility was identified as lectin and non-specific lipid-transfer protein 1 using MALDI-TOF mass spectrometry analysis.
February 1, 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28140750/production-of-a-protease-inhibitor-from-edible-mushroom-agaricus-bisporus-and-its-statistical-optimization-by-response-surface-methodology
#12
Reena Vishvakarma, Abha Mishra
The production of a protease inhibitor from Agaricus bisporus through solid state fermentation was studied. The purpose was to produce protease inhibitor from natural, cheap and readily available carbon and nitrogen sources. Solid state fermentation enhanced the mycelia growth and also gave a higher yield of the product. Further, fungal growth and other production parameters were statistically optimized. The specificity of the inhibitor was tested and was effective against trypsin. Screening of significant factors (wheat bran, cyanobacterial biomass, initial pH, temperature, incubation period, and moisture content and inoculum size) was done using Plackett-Burman Design...
January 31, 2017: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/28139469/co-au-multisegmented-nanowires-a-3d-array-of-magnetostatically-coupled-nanopillars
#13
C Bran, Yu P Ivanov, J Kosel, O Chubykalo-Fesenko, M Vazquez
Arrays of multisegmented Co/Au nanowires with designed segment lengths and diameters have been prepared by electrodeposition into aluminum oxide templates. The high quality of the Co/Au interface and the crystallographic structure of Co segments have determined by high-resolution transmission electron microscopy. Magnetic hysteresis loop measurements show larger coercivity and squareness of multisegmented nanowires as compared to single segment Co nanowires. The complementary micromagnetic simulations are in good agreement with the experimental results, confirming that the magnetic behavior is defined mainly by magnetostatic coupling between different segments...
March 3, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28135406/mycotoxin-contamination-of-rice-in-china
#14
REVIEW
Xiang Dong Sun, Ping Su, Hong Shan
Mycotoxin contamination in rice is generally lower than in other cereals such as corn or wheat. However, over 65% of the population in China consumes rice as a staple food. Due to the diversity of the climate across China, the southern region is characterized by high temperatures and humidities, especially in rainy season. Such conditions are optimal for the growth of fungi. The accumulative and transferrable characteristics of fungi mycotoxins pose a great potential threat as confirmed by high incidences of liver cancer in the Yangtze delta region...
January 30, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28133820/dietary-inclusion-of-tomato-pomace-improves-meat-oxidative-stability-of-young-pigs
#15
C S Correia, C M Alfaia, M S Madeira, P A Lopes, T J S Matos, L F Cunha, J A M Prates, J P B Freire
The aim of this study was to assess the nutritional effect of tomato pomace, in combination with two distinct fat sources (lard or soya bean oil), on longissimus lumborum muscle, subcutaneous fat and liver of young pigs. Forty male pigs of 4 weeks old were randomly assigned to four dietary treatments using two fibre sources (wheat bran or 5.0% tomato pomace) and two fat sources (lard or soya bean oil), in a 2 × 2 factorial design for a 5-week trial. Tomato pomace did not improve colour, fatty acid profile, cholesterol content or lipid oxidation, nor did it yield detectable levels in lycopene or β-carotene in the meat (p > 0...
January 30, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28124676/a-34-year-old-man-with-back-pain
#16
D J L van Twist, R J J M van de Laar, R J B Brans, J W J Refos, A A Kroon
No abstract text is available yet for this article.
January 2017: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/28122932/greater-adherence-to-cancer-prevention-guidelines-is-associated-with-higher-circulating-concentrations-of-vitamin-d-metabolites-in-a-cross-sectional-analysis-of-pooled-participants-from-2-chemoprevention-trials
#17
Lindsay N Kohler, Elizabeth A Hibler, Robin B Harris, Eyal Oren, Denise J Roe, Peter W Jurutka, Elizabeth T Jacobs
BACKGROUND: Several lifestyle factors targeted by the American Cancer Society (ACS) Nutrition and Physical Activity Cancer Prevention Guidelines are also associated with circulating concentrations of vitamin D metabolites. This suggests that greater adherence to the ACS guidelines may be related to better vitamin D status. OBJECTIVE: We examined the relation between adherence to the ACS guidelines and circulating concentrations of 2 vitamin D metabolites, 25-hydroxycholecalciferol [25(OH)D] and 1α,25-dihydroxyvitamin D [1,25(OH)2D]...
January 25, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28121194/in-vitro-characterization-studies-of-self-microemulsified-bosentan-systems
#18
Harini Chowdary Vadlamudi, Prasanna Raju Yalavarthi, M V Basaveswara Rao, Arun Rasheed, Tejeswari N
CONTEXT: Bosentan is a poorly soluble drug and pose challenges in design delivery systems. OBJECTIVE: To enhance the solubility, dissolution and shelf-life of bosentan by formulating it as S-SMEDDS capsules. MATERIALS AND METHODS: Solubility of bosentan was tested in various liquid vehicles such as oils (rice bran and sunflower), surfactants (span 20 and tween 80) and co-surfactants (PEG 400 and propylene glycol) and microemulsions were developed...
January 25, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28118576/accelerated-solvent-extraction-of-insecticides-from-rice-hulls-rice-bran-and-polished-rice-grains
#19
Gustavo Mack Teló, Scott Allen Senseman, Enio Marchesan, Edinalvo Rabaioli Camargo, Katherine Carson
Analysis of pesticide residues in irrigated rice grains is important for food security. In this study, we analyzed accelerated solvent extraction (ASE) conditions for the extraction of thiamethoxam and chlorantraniliprole insecticides from rice hulls, rice bran, and polished rice grains. Several variables, including extraction solvent, extraction temperature, extraction pressure, cell size, static extraction time, and sample concentration, were investigated. The average recoveries of the three matrixes were between 89...
December 23, 2016: Journal of AOAC International
https://www.readbyqxmd.com/read/28117694/wheat-bran-does-not-affect-postprandial-plasma-short-chain-fatty-acids-from-13-c-inulin-fermentation-in-healthy-subjects
#20
Lise Deroover, Joran Verspreet, Anja Luypaerts, Greet Vandermeulen, Christophe M Courtin, Kristin Verbeke
Wheat bran (WB) is a constituent of whole grain products with beneficial effects for human health. Within the human colon, such insoluble particles may be colonized by specific microbial teams which can stimulate cross-feeding, leading to a more efficient carbohydrate fermentation and an increased butyrate production. We investigated the extent to which WB fractions with different properties affect the fermentation of other carbohydrates in the colon. Ten healthy subjects performed four test days, during which they consumed a standard breakfast supplemented with 10 g (13)C-inulin...
January 20, 2017: Nutrients
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