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https://www.readbyqxmd.com/read/28525627/geographic-patterns-of-autism-spectrum-disorder-among-children-of-nurses-health-study-ii-women
#1
Kate Hoffman, Marc G Weisskopf, Andrea L Roberts, Raanan Raz, Jaime E Hart, Kristen Lyall, Elin M Hoffman, Francine Laden, Verónica M Vieira
Data indicate that autism spectrum disorder (ASD) prevalence may be increasing and varies geographically. We investigated associations between residential location and ASD in the children of Nurses' Health Study II women in order to generate hypotheses about social and environmental factors related to etiology or diagnosis. Analyses included 13,507 children born from 1989-1999 (486 with ASD). We explored relationships between ASD and residential location at both birth and age 6 years (i.e. closer to average diagnosis age)...
May 19, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28525603/genome-wide-association-study-of-psychosis-proneness-in-the-finnish-population
#2
Alfredo Ortega-Alonso, Jesper Ekelund, Antti-Pekka Sarin, Jouko Miettunen, Juha Veijola, Marjo-Riitta Järvelin, William Hennah
The current study examined quantitative measures of psychosis proneness in a nonpsychotic population, in order to elucidate their underlying genetic architecture and to observe if there is any commonality to that already detected in the studies of individuals with overt psychotic conditions, such as schizophrenia and bipolar disorder. Heritability, univariate and multivariate genome-wide association (GWAs) tests, including a series of comprehensive gene-based association analyses, were developed in 4269 nonpsychotic persons participating in the Northern Finland Birth Cohort 1966 study with information on the following psychometric measures: Hypomanic Personality, Perceptual Aberration, Physical and Social Anhedonia (also known as Chapman's Schizotypia scales), and Schizoidia scale...
May 19, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28522355/closed-versus-open-vitrification-for-human-blastocyst-cryopreservation-a-meta-analysis
#3
Hyun Sik Youm, Jong-Ryeol Choi, Daesik Oh, Yong Ho Rho
Closed vitrification can minimize the risk of microbiological transmission through liquid nitrogen during the cooling, storage, and warming procedures. As cooling rates may reduce when closed vitrification is applied, clinical outcomes should be compared between closed and open vitrification in order to justify the use of closed vitrification. This study was conducted to investigate the differences in survival, implantation, clinical pregnancy, and live birth rates between closed and open vitrification for human blastocyst cryopreservation...
May 15, 2017: Cryobiology
https://www.readbyqxmd.com/read/28515184/trends-and-population-attributable-risk-estimates-for-predictors-of-early-neonatal-mortality-in-nigeria-2003-2013-a-cross-sectional-analysis
#4
Osita Kingsley Ezeh
OBJECTIVES: To assess trends in early neonatal mortality (ENM) and population-attributable risk (PAR) estimates for predictors of ENM in Nigeria. DESIGN, SETTING AND PARTICIPANTS: A cross-sectional data on 63 844 singleton live births within the preceding 5 years from the 2003, 2008 and 2013 Nigeria Demographic and Health Surveys were used. Adjusted PARs were used to estimate the number of early neonatal deaths attributable to each predictor in the final multivariable Cox regression model...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28514952/distributions-and-determinants-of-urinary-biomarkers-of-organophosphate-pesticide-exposure-in-a-prospective-spanish-birth-cohort-study
#5
Sabrina Llop, Mario Murcia, Carmen Iñiguez, Marta Roca, Llúcia González, Vicent Yusà, Marisa Rebagliato, Ferran Ballester
BACKGROUND: Prenatal exposure to organophosphate pesticides (OPs) has been associated with impaired child development. Pesticide exposure determinants need to be studied in order to identify sources and pathways of pesticide exposure. The aim of this paper is to describe prenatal exposure to OPs and evaluate the associated factors in pregnant women. METHODS: The study population consisted of pregnant women (n = 573) who participated in the INMA birth cohort study in Valencia (Spain, 2003-2006)...
May 17, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28508691/corifollitropin-alfa-compared-with-follitropin-beta-in-gnrh-antagonist-ovarian-stimulation-protocols-in-an-unselected-population-undergoing-ivf-icsi
#6
Charalampos Siristatidis, Konstantinos Dafopoulos, Nikolas Christoforidis, George Anifandis, Vasileios Pergialiotis, Nikolaos Papantoniou
Recombinant DNA technologies have produced Corifollitropin alfa (CFa) used during IVF/ICSI in order to keep the circulating FSH levels above the threshold necessary to support multi-follicular growth for a week. In this prospective case-control study, we compared 70 participants treated with 150 μg CFa combined with 150 IU of follitropin beta (study group) with 70 subfertile participants with matching baseline characteristics, conforming with the same inclusion criteria and treated with an antagonist protocol using follitropin beta (control group)...
May 16, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28506179/value-of-soft-tissue-release-procedure-around-the-shoulder-to-improve-shoulder-abduction-in-birth-brachial-plexus-palsy-and-analysis-of-the-factors-affecting-outcome
#7
S Raja Sabapathy, Praveen Bhardwaj, Hari Venkatramani
BACKGROUND: A lack of shoulder abduction in spontaneously recovered birth brachial plexus palsy (BBPP) is a common presentation. We have performed a soft tissue release operation in these patients to remove the tethering effect of the tight and cocontracting shoulder adductors. This study was undertaken in order to assess the outcome of this surgical procedure. METHODS: We performed a retrospective analysis of 120 patients who displayed spontaneous recovery from BBPP and subsequently underwent soft tissue release procedure to improve shoulder abduction...
June 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28504029/obstetric-brachial-plexus-palsy-a-population-based-retrospective-case-control-study-and-medicolegal-considerations
#8
Simona Zaami, Francesco Paolo Busardò, Fabrizio Signore, Nicola Felici, Vito Briganti, Giovanni Baglio, Enrico Marinelli, Vittorio Fineschi
AIMS: The aim of this study was to examine 24 cases of obstetric brachial plexus palsy (OBPP) in 41,002 deliveries occurred at San Camillo-Forlanini Hospital in Rome, during the period 2000-2012. MATERIALS AND METHODS: A population-based retrospective case-control study was designed and the database of the hospital was searched; for each case, maternal and fetal records were examined and some risk factors were evaluated. RESULTS: A statistically significant association between the 24 cases OBPP and the following risk factors: primiparity (p < ...
May 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28501279/clinical-and-laboratory-markers-in-the-recovery-from-severe-preeclampsia
#9
Reut Rotem, Avital Bilitzky, Tamar Abady Nezer, Igal Plakht, Adi Y Weintraub
OBJECTIVE: To examine the recovery from severe Preeclampsia toxemia (PET) in women treated with magnesium sulfate (MgSO4) during the first 24h postpartum as reflected by the changes in various clinical and laboratory markers. STUDY DESIGN: The study population included all women diagnosed with severe PET that gave birth at the Soroka University Medical center between 2013 and 2014, and were treated with MgSO4 in the first 24h postpartum. Data were collected from the institutional computerized records...
April 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/28495268/the-presence-of-vegf-and-notch2-during-preantral-antral-follicular-transition-in-infantile-rats-anatomical-evidence-and-its-implications
#10
Minerva Carolina Torres-Ortiz, Gabriel Gutiérrez-Ospina, Margarita Gómez-Chavarín, Clara Murcia, Rogelio A Alonso-Morales, Gerardo Perera-Marín
Folliculogenesis is a process that depends on angiogenesis, in which VEGF and Notch signaling pathway members are involved. Although this pathway is present in preantral and antral follicular structures during the second stage of folliculogenesis, this association has not been described. Therefore, this study aimed to identify VEGF and Notch2 in ovary structures of infantile rats after induction of follicular development with a gonadotropin stimulus. In order to explore this possibility we analyzed rat ovary morphology from days 10-25 after birth; subsequently, the transition from preantral follicle to an antral stage was analyzed by the induction of follicular development with equine chorionic gonadotropin (eCG) and VEGF and Notch were identified in the rat ovary by fluorescence...
May 8, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28494594/caring-for-baby-s-teeth-starts-before-birth
#11
L Paglia
Care for a child's teeth and gums can start even before the baby is born. Pregnancy causes many hormonal changes, among these the rise of estrogen and progesterone increases the risk of developing oral health problems, like gingivitis and periodontitis.The presence of maternal periodontal diseases and active infections has been associated with adverse pregnancy outcomes, such as preterm birth, preeclampsia, gestational diabetes and foetal loss. Therefore, it is important to educate pregnant women about their oral hygiene and the importance of taking care of their newborn's oral health...
March 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28494319/no-baby-booms-or-birth-sex-ratio-changes-following-fifty-shades-of-grey-in-the-united-states
#12
Victor Grech
INTRODUCTION: The Fifty Shades of Grey (FSOG) trilogy were publicised by the media as inflaming increased coital activity, and that this would result a baby boom. Furthermore, increased coital activity skews the sex ratio at birth (M/T) toward male births. This study was carried out in order to ascertain whether there were any spikes in total births or in M/T in the United States (US) circa nine months following the FSOG books. METHODS: Monthly male and female births for the US were obtained directly from the website of the Centre for Disease Control (01/2007-12/2015)...
May 8, 2017: Early Human Development
https://www.readbyqxmd.com/read/28489890/unmasking-inequalities-sub-national-maternal-and-child-mortality-data-from-two-urban-slums-in-lagos-nigeria-tells-the-story
#13
Erin Anastasi, Ekanem Ekanem, Olivia Hill, Agnes Adebayo Oluwakemi, Oluwatosin Abayomi, Andrea Bernasconi
INTRODUCTION: Nigeria has one of the highest maternal mortality ratios in the world as well as high perinatal mortality. Unfortunately, the country does not have the resources to assess this critical indicator with the conventional health information system and measuring its progress toward the goal of ending preventable maternal deaths is almost impossible. Médecins Sans Frontières (MSF) conducted a cross-sectional study to assess maternal and perinatal mortality in Makoko Riverine and Badia East, two of the most vulnerable slums of Lagos...
2017: PloS One
https://www.readbyqxmd.com/read/28482821/understanding-coping-strategies-during-pregnancy-and-the-postpartum-period-a-qualitative-study-of-women-living-with-hiv-in-rural-uganda
#14
Scholastic Ashaba, Angela Kaida, Bridget Frances Burns, Kasey O'Neil, Emma Dunkley, Christina Psaros, Jasmine Kastner, Alexander C Tsai, David R Bangsberg, Lynn T Matthews
BACKGROUND: In sub-Saharan Africa, 58% of adults living with HIV are women. In Uganda, HIV prevalence is 8.3% for women compared to 6.1% for men. Access to antiretroviral therapy (ART) and prevention of mother to child transmission (PMTCT) programs have enabled women living with HIV (WLWH) to have children with minimal risk of perinatal transmission. Nevertheless, pregnant WLWH face many challenges. We explored women's perceptions of how they cope with the challenges of pregnancy and the postpartum period as HIV-infected women...
May 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28482725/umbilical-cord-blood-and-maternal-visfatin-pbef-nampt-concentrations-in-preterm-birth-with-and-without-preterm-premature-rupture-of-membranes
#15
Tereza Pavlová, Filip Zlámal, Zbyněk Šplíchal, Josef Tomandl, Zuzana Hodická, Pavel Ventruba, Julie Bienertová-Vašků
OBJECTIVES: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within 7 days and after more than 7 days following admission for PTB/preterm premature rupture of membranes (PPROM). METHODS: Maternal peripheral blood and cord blood was collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (3 with PPROM). RESULTS: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p = 0...
May 9, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28480845/risk-factors-of-cleft-lip-and-palate-in-georgia
#16
S Chincharadze, Z Vadachkoria, I Mchedlishvili
A case-control study was conducted to reveal risk factors for cleft lip and palate. The main group consisted of 41mothers of infants with orofacial clefts (cleft lip and/or palate) who were born in Tbilisi maternity houses during 2015-2016. The control group was composed of 61 mothers who have given birth to healthy babies in the same maternity houses. Information on possible risk factors was collected using a special form. In order to evaluate a role of these risk factors, bivariate analysis was conducted at the first stage of the study...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28479309/-apnoea-in-infants-with-bronchiolitis-incidence-and-risk-factors-for-a-prediction-model
#17
José Miguel Ramos-Fernández, David Moreno-Pérez, Mario Gutiérrez-Bedmar, María Ramírez-Álvarez, Yasmina Martínez García, Lourdes Artacho-González, Antonio Urda-Cardona
INTRODUCTION: The presence of apnoea in acute bronchiolitis (AB) varies between 1.2% and 28.8%, depending on the series, and is one of its most fearsome complications. The aim of this study is to determine the incidence of apnoea in hospitalised patients diagnosed with AB, and to define their associated risk factors in order to construct a prediction model. PATIENTS AND METHOD: A retrospective observational study of patients admitted to a tertiary hospital in the last 5 years with a diagnosis of AB, according to the classic criteria...
May 4, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28477295/do-tort-reforms-impact-the-incidence-of-birth-by-cesarean-section-a-reassessment
#18
Javier Cano-Urbina, Daniel Montanera
Investigations into the existence and impact of defensive medicine in obstetrics have produced mixed and often conflicting implications. The most widely-cited and accepted results in this literature find that less severe malpractice environments cause an increase in the use of cesarean section. This has been interpreted as "offensive medicine"; taking advantage of lenient malpractice environments by providing unnecessary services in order to raise revenue. In this article we show that an assumption concerning births with an unknown method of delivery, which is not explicitly stated in the literature, is pivotal in obtaining these results...
March 2017: International Journal of Health Economics and Management
https://www.readbyqxmd.com/read/28477150/the-optimal-angle-of-the-mediolateral-episiotomy-at-crowning-of-the-head-during-labor
#19
Shimon Ginath, Osnat Elyashiv, Eran Weiner, Ron Sagiv, Jacob Bar, Joseph Menczer, Michal Kovo, Alexander Condrea
INTRODUCTION AND HYPOTHESIS: The aim of the mediolateral episiotomy incision is to increase the diameter of the soft tissue of the vaginal outlet to facilitate birth and to prevent vaginal tears. Episiotomy angles that are too narrow and close to the midline increase the risk of obstetric anal sphincter injuries. In order to determine the optimal angle of the episiotomy, we assessed the changes in the angles of episiotomy lines marked during the first stage of labor and measured at the time of crowning of the head...
May 5, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28475644/measuring-three-aspects-of-motivation-among-health-workers-at-primary-level-health-facilities-in-rural-tanzania
#20
Miho Sato, Deogratias Maufi, Upendo John Mwingira, Melkidezek T Leshabari, Mayumi Ohnishi, Sumihisa Honda
BACKGROUND: The threshold of 2.3 skilled health workers per 1,000 population, published in the World Health Report in 2006, has galvanized resources and efforts to attain high coverage of skilled birth attendance. With the inception of the Sustainable Development Goals (SDGs), a new threshold of 4.45 doctors, nurses, and midwives per 1,000 population has been identified. This SDG index threshold indicates the minimum density to respond to the needs of health workers to deliver a much broader range of health services, such as management of non-communicable diseases to meet the targets under Goal 3: Ensure healthy lives and promote well-being for all people of all ages...
2017: PloS One
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