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https://www.readbyqxmd.com/read/29050375/interstitial-fluid-pressure-of-thymic-epithelial-tumours
#1
Takeshi Mori, Wataru Nishi, Tatsuya Yamada, Yamato Motooka, Koei Ikeda, Kenji Shiraishi, Makoto Suzuki
Tumours show an increased interstitial fluid pressure, which correlates with various pathophysiological features. Moreover, interstitial fluid pressure is a prognostic factor for cervical and lung cancer. However, there have been no reports on the usefulness of measuring interstitial fluid pressure in thymic epithelial tumours. Therefore, this study aimed to examine the relationship between interstitial fluid pressure and the clinicopathological characteristics of thymic epithelial tumours. Interstitial fluid pressure was prospectively measured at the centre of the tumour using a 1-Fr Mikro-Tip sensor catheter in 44 patients with thymic epithelial tumours, 40 with thymomas and 4 with thymic carcinomas...
August 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29050188/-sturge-weber-syndrome-in-port-wine-stain-patients-a-retrospective-study-on-the-clinical-features-and-screening-strategy
#2
Y Wu, R J Yu, X X Lin, W Y Guo
Objective: To investigate the clinical characteristics of Sturge-Weber syndrome (SWS) in the patients with Port-wine stain (PWS). Methods: A total of 279 PWS patients, 164 males, 115 females with a median age of first visit 17.00 (4.75, 56.00) months. Most of the PWS patients were referred to the Ophthalmology Department for screening eye problems when the cutaneous angiomas involved the ophthalmic division of the trigeminal nerve distribution. The intraocular pressure (IOP), cup to disk ratio (C/D), corneal condition and other essential measurements were examined to screen glaucoma or choroidal hemangioma...
October 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29050187/-cytokine-analysis-of-aqueous-humor-in-aids-patients
#3
W J Kong, C G Guo, L Y Xie, W B Wei, H W Dong, C Chen, K F Du
Objective: To explore the Cytokine of aqueous humor in AIDS patients with different eye diseases. Methods: A case-control study including 38 patients who was diagnosed as acquired immunodeficiency syndrome(AIDS) at Infectious Center and Department of Ophthalmology in Beijing You'an Hospital, Capital Medical University. And 16 cases of 38 patients were cytomegalovirus retinitis (CMVR), 14 cases were HIV-related retinal disease, and 8 cases presented as normal. A series of tests were performed including vision acuity check, intraocular pressure, fundus photography, blood cell count of CD4+ T lymphocyte and the content of cytokines in aqueous humor by Luminex 200(TM) liquid chip analyzer...
October 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29050186/-influent-factors-for-treating-procedure-of-cytomegalovirus-retinitis-after-allogeneic-bone-marrow-hematopoietic-stem-cell-transplantation
#4
H Miao, J Hou
Objective: To explore clinical and laboratory factors that influencing treating procedure of cytomegalovirus retinitis (CMVR) after allogeneic bone marrow hematopoietic stem cell transplantation (HSCT). Methods: This is a retrospective case series study. A total of 9 CMVR patients (15 eyes) between January 2016 and March 2017 were included in this study. All patients received intravenous or oral ganciclovir, together with intravitreous injection of ganciclovir alone or combined with foscanet sodium. One day before the first injection, aqueous humor samples from the affected eyes were collected, and CMV-DNA and interleukin-8 (IL-8) level were examined...
October 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29050155/-correlation-factors-of-127-times-pre-crisis-state-in-patients-with-myasthenia-gravis
#5
C Y Ou, H Ran, L Qiu, Z D Huang, Z Z Lin, J Deng, W B Liu
Objective: To investigate the clinical features of the Pre-Crisis State and analyze the correlated risk factors of Pre-Crisis State of myasthenia crisis. Methods: We included 93 patients with myasthenia gravis (MG) who experienced 127 times Pre-Crisis State between October 2007 and July 2016. Those patients were hospitalized in the MG specialize center, Department of Neurological Science, first Affiliated Hospital of Sun Yat-sen University. The information of the general situation, the clinical manifestations and the blood gas analysis in those patients were collected using our innovated clinical research form...
October 10, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29050087/-study-on-the-correlation-between-meteorological-factors-and-acute-otitis-media-in-outpatients-of-children-in-beijing
#6
Y X Lu, J Q Liang, Q L Gu, X M Yu, X Yan
Objective: To explore the characteristics of acute otitis media(AOM) in children in Beijing and its correlation with meteorological factors. Methods: Data were collected in 2011-2013 in the Otolaryngology Department of Capital Institute of Pediatrics. AOM in children with relevant information, such as age, sex and season, with the same period of the Beijing municipal meteorological data (the average temperature, average pressure, average wind speed, humidity and PM2.5) were compared to analysis the relationship of meteorological environmental parameters and the onset of AOM in children...
October 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29050062/-cerebral-emergency-important-anesthesiological-aspects
#7
Martin Schott, Klaus-Peter Stein, Martin Bauer
The anesthesiological management of cerebral emergency represents a great challenge for action under pressure and under time pressure and requires smooth interprofessional cooperation. The exact knowledge of the pathophysiological and pharmacological relationships is the basis for rapid identification of therapeutic influences and possible disturbing factors. In the acute situation, paCO2 and MAP are the central determinants for the anesthetist to ensure cerebral perfusion and the resulting cerebral oxygenation...
October 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/29050041/lower-limb-force-velocity-power-capabilities-during-leg-press-and-squat-movements
#8
Johnny Padulo, Gian Mario Migliaccio, Luca Paolo Ardigò, Bruno Leban, Marco Cosso, Pierre Samozino
The aim was to compare lower-limb power, force, and velocity capabilities between squat and leg press movements. Ten healthy sportsmen performed ballistic lower-limb push-offs against 5-to-12 different loads during both the squat and leg press. Individual linear force-velocity and polynomial power-velocity relationships were determined for both movements from push-off mean force and velocity measured continuously with a pressure sensor and linear encoder. Maximal power output, theoretical maximal force and velocity, force-velocity profile and optimal velocity were computed...
October 19, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29050039/cardiac-autonomic-dysfunction-in-offspring-of-hypertensive-parents-during-exercise
#9
Leonardo Barbosa de Almeida, Tiago Peçanha, Pedro Augusto de Carvalho Mira, Livia Victorino de Souza, Lílian Pinto da Silva, Daniel Godoy Martinez, Isabelle Magalhães Guedes Freitas, Mateus Camaroti Laterza
Offspring of hypertensive parents present autonomic dysfunction at rest and during physiological maneuvers. However, the cardiac autonomic modulation during exercise remains unknown. This study tested whether the cardiac autonomic modulation would be reduced in offspring of hypertensive parents during exercise. Fourteen offspring of hypertensive and 14 offspring of normotensive individuals were evaluated. The groups were matched by age (24.5±1.0 vs. 26.6±1.5 years; p=0.25) and BMI (22.8±0.6 vs. 24.2±1.0 kg/m(2); p=0...
October 19, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29050005/effect-of-salt-intake-on-serum-glucagon-like-peptide-1-levels-in-normotensive-salt-sensitive-subjects
#10
Wen-Ling Zheng, Chao Chu, Yong-Bo Lv, Yang Wang, Jia-Wen Hu, Qiong Ma, Yu Yan, Yu-Meng Cao, Xi-Long Dang, Ke-Ke Wang, Jian-Jun Mu
BACKGROUND/AIMS: Excess dietary salt is a critical risk factor of salt-sensitive hypertension. Glucagon-like peptide-1 (GLP-1) , a gut incretin hormone, conferring benefits for blood pressure by natriuresis and diuresis. We implemented a randomized trial to verify the effect of altered salt intake on serum GLP-1 level in human beings. METHODS: The 38 subjects were recruited from a rural community of Northern China. All subjects were sequentially maintained a baseline diet period for 3 days, a low-salt diet period for 7 days (3...
October 19, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29049887/all-atom-molecular-dynamics-based-analysis-of-membrane-stabilizing-copolymer-interactions-with-lipid-bilayers-probed-under-constant-surface-tensions
#11
Evelyne M Houang, Frank S Bates, Yuk Yin Sham, Joseph M Metzger
An all-atom phospholipid bilayer and triblock copolymer model was developed for Molecular Dynamics (MD) studies. These were performed to investigate the mechanism of interaction between membrane stabilizing triblock copolymer P188 and 1-palmitoyl-2-oleoyl-sn- glycero-3-phosphatidylcholine (POPC) lipid bilayers under applied lateral surface tension (γ) to model membrane mechanical stress. Results showed that P188 insertion is driven by the hydrophobic polypropylene oxide (PPO) core and dependent on bilayer area per lipid...
October 19, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29049881/effect-of-the-alkanoyl-group-position-at-the-glycerol-backbone-on-the-monolayer-characteristics-demonstrated-by-2-monopalmitoyl-rac-glycerol
#12
Dieter Vollhardt, Gerald Brezesinski, Rainer Rudert, Antonio Gonzalez
The influence of the position of the aliphatic chain at the glycerol backbone has been basically unknown. Solely the results of 2-monopalmitoyl-rac-glycerol obtained at ≥13 °C indicated an essential influence of the position of the palmitoyl group at the glycerol backbone, substantiated by a disordered packing of the alkyl chains. Therefore, the present study extends the comprehensive characterization of 2-monopalmitoyl-rac-glycerol monolayers to the low temperature range for highlighting the effect of the position of the aliphatic chain at the glycerol backbone of monoalkanoylglycerolester monolayers...
October 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29049880/crystalline-ordering-and-large-fugacity-expansion-for-hard-core-lattice-particles
#13
Ian Jauslin, Joel L Lebowitz
Using an extension of Pirogov-Sinai theory we prove phase transitions, corresponding to sublattice orderings, for a general class of hard-core lattice particle systems with a finite number of perfect coverings. These include many cases for which such transitions have been proven. The proof also shows that, for these systems, the Gaunt- Fisher expansion of the pressure in powers of the inverse fugacity (aside from an explicit logarithmic term) has a nonzero radius of convergence.
October 19, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29049836/fluid-accumulation-after-closure-of-atrial-septal-defects-the-role-of-colloid-osmotic-pressure
#14
Marianne Indrebø, Ansgar Berg, Henrik Holmstrøm, Egil Seem, Hans Jørgen Guthe, Helge Wiig, Gunnar Norgård
OBJECTIVES: Following paediatric cardiac surgery with cardiopulmonary bypass (CPB), there is a tendency for fluid accumulation. The colloid osmotic pressure of plasma (COPp) and interstitial fluid (COPi) are determinants of transcapillary fluid exchange but only COPp has been measured in sick children. The aim of this study was to assess the net colloid osmotic pressure gradient in children undergoing atrial septal defect closure. METHODS: Twenty-three patients had interventional and 18 had surgical atrial septal defect closures...
October 10, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049796/surgical-strategy-for-aortic-arch-reconstruction-after-the-norwood-procedure-based-on-numerical-flow-analysis
#15
Shohei Miyazaki, Kagami Miyaji, Keiichi Itatani, Norihiko Oka, Shinji Goto, Masanori Nakamura, Tadashi Kitamura, Tetsuya Horai, Koichi Sughimoto, Yuki Nakamura, Naoki Yoshimura
OBJECTIVES: Inefficient aortic flow after the Norwood procedure is known to lead to the deterioration of ventricular function due to an increased cardiac workload. To prevent the progression of aortic arch obstruction, arch reconstruction concomitant with second-stage surgery is recommended. The aim of this study was to determine the indications for reconstruction based on numerical simulation and to reveal the morphology that affects the haemodynamic parameters. METHODS: Fifteen patients who underwent the Norwood procedure or arch repair and Damus-Kaye-Stansel anastomosis were enrolled...
October 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049777/annals-consult-guys-mythbuster-preoperative-blood-pressure-control
#16
Geno J Merli, Howard H Weitz
No abstract text is available yet for this article.
October 17, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29049749/transvalvular-pressure-gradients-for-different-methods-of-mitral-valve-repair-only-neochordoplasty-achieves-native-valve-gradients
#17
Silje Ekroll Jahren, Samuel Hurni, Paul Philipp Heinisch, Bernhard Winkler, Dominik Obrist, Thierry Carrel, Alberto Weber
OBJECTIVES: Many surgical and interventional methods are available to restore patency for patients with degenerative severe mitral valve regurgitation. Leaflet resection and neochordoplasty, which both include ring annuloplasty, are the most frequently performed techniques for the repair of posterior mitral leaflet flail. It is unclear which technique results in the best haemodynamics. In this study, we investigated the effect of different mitral valve reconstruction techniques on mitral valve haemodynamics and diastolic transvalvular pressure gradient in an ex vivo porcine model...
October 3, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049743/additional-veno-venous-gas-exchange-as-a-problem-solving-strategy-for-an-oxygenator-not-transferring-oxygen-in-paediatric-cardiopulmonary-bypass
#18
Wolfgang Boettcher, Nicodème Sinzobahamvya, Frank Dehmel, Andreas Matschke, Andre Iben, Mi-Young Cho, Mathias Redlin, Joachim Photiadis
OBJECTIVES: Oxygenator failure during cardiopulmonary bypass constitutes a life-threatening event, especially when perfusion is conducted under normothermia. An alternative solution to emergency oxygenator changeover is described. METHODS: A supplementary oxygenator is added in the venous line without interrupting perfusion. De-airing is achieved through the cardiotomy reservoir. Oxygen supply is adapted to ensure physiologic partial oxygen pressure. RESULTS: On 5 occasions in the past 4 years, Capiox Baby FX 05 oxygenator ( n  = 4) and Capiox FX15 ( n  = 1) failed to exchange blood gases after bypass run ranging from 290 min to 563 min...
June 20, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049738/a-genome-wide-scan-for-microrna-related-genetic-variants-associated-with-primary-open-angle-glaucoma
#19
Mohsen Ghanbari, Adriana I Iglesias, Henriët Springelkamp, Cornelia M van Duijn, M Arfan Ikram, Abbas Dehghan, Stefan J Erkeland, Caroline C W Klaver, Magda A Meester-Smoor
Purpose: To identify microRNAs (miRNAs) involved in primary open-angle glaucoma (POAG), using genetic data. MiRNAs are small noncoding RNAs that posttranscriptionally regulate gene expression. Genetic variants in miRNAs or miRNA-binding sites within gene 3'-untranslated regions (3'UTRs) are expected to affect miRNA function and contribute to disease risk. Methods: Data from the recent genome-wide association studies on intraocular pressure, vertical cup-to-disc ratio (VCDR), cupa area and disc area were used to investigate the association of miRNAs with POAG endophenotypes...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29049724/patients-with-normal-tension-glaucoma-have-relative-sparing-of-the-relative-afferent-pupillary-defect-compared-to-those-with-open-angle-glaucoma-and-elevated-intraocular-pressure
#20
Mitchell Lawlor, Ana Quartilho, Catey Bunce, Neil Nathwani, Emily Dowse, Debbie Kamal, Gus Gazzard
Purpose: We determined whether there is relative sparing of pupil function in glaucoma patients with normal pressures compared to those with high pressures. Methods: A cross-sectional study was done of 68 patients with primary open angle glaucoma (POAG): 38 had normal IOPs on all-day phasing before treatment (never >21 mm Hg), with confirmed progression of glaucomatous optic neuropathy (NTG) and 30 had glaucomatous optic neuropathy associated with elevated intraocular pressures (>25 mm Hg; HP-POAG)...
October 1, 2017: Investigative Ophthalmology & Visual Science
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