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https://www.readbyqxmd.com/read/29684934/-optimal-medical-therapy-and-secondary-prevention-in-patients-after-an-acute-coronary-syndrome
#1
Barbara E Stähli, Ulf Landmesser
Antithrombotic therapy and other secondary preventive measures such as lifestyle changes, lipid lowering and blood pressure control, along with coronary revascularization strategies, can markedly improve clinical outcomes in patients after an acute coronary syndrome. Current guideline-recommended secondary preventive measures in patients with a recent acute coronary syndrome event according to the European Society of Cardiology (ESC) are summarized in this review.
May 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29684868/utilization-of-acetone-butanol-ethanol-water-mixture-obtained-from-biomass-fermentation-as-renewable-feedstock-for-hydrogen-production-via-steam-reforming-thermodynamic-and-energy-analyses
#2
Brajesh Kumar, Shashi Kumar, Shishir Sinha, Surendra Kumar
A thermodynamic equilibrium analysis on steam reforming process to utilize acetone-butanol-ethanol-water mixture obtained from biomass fermentation as biorenewable fuel has been performed to produce clean energy carrier H2 via non-stoichiometric approach namely Gibbs free energy minimization method. The effect of process variables such as temperature (573-1473 K), pressure (1-10 atm), and steam/fuel molar feed ratio (FABE  = 5.5-12) have been investigated on equilibrium compositions of products, H2 , CO, CO2 , CH4 and solid carbon...
April 12, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29684822/sexual-dysfunction-among-nigerian-women-with-epilepsy
#3
Luqman Ogunjimi, Joseph Yaria, Akintomiwa Makanjuola, Adesola Ogunniyi
OBJECTIVES: Sexual dysfunction (SD) has been shown to be more prevalent among females with epilepsy (FWE) when compared with controls. Identified risk factors for SD among FWE include depression, antiepileptic drug (AED) type, epileptic lateralization, and temporal lobe involvement. Despite a huge population of FWE in sub-Saharan Africa and by extension Nigeria, there are limited studies on the effect of AEDs and epilepsy on sexual function among FWE in the region. We therefore studied predictors and patterns of SD among Nigerian FWE...
April 20, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29684779/iron-loaded-sphagnum-moss-extract-residue-for-phosphate-removal
#4
Ruichi Zhang, Tiina Leiviskä, Sanna Taskila, Juha Tanskanen
Sphagnum moss extract residue (SMER), obtained after pressurized hot water extraction, was modified with Fe(III) and investigated for phosphate sorption. Although moss extract contains value-added compounds, SMER is considered to be waste until suitable uses can be developed. The effect of modification conditions were investigated, i.e. different initial Fe(III) concentrations (0.024, 0.048 and 0.072 mol/L Fe3+ ) and modification pH values (5, 7 and 9). A modification pH of 5 and the highest initial Fe(III) concentration (0...
April 20, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29684741/age-related-changes-in-the-range-and-velocity-of-postural-sway
#5
REVIEW
Danuta Roman-Liu
The aim of this analysis was to compare values of centre of pressure (CoP) measures, which describe the ability to maintain static body balance (range of body sway and velocity in antero-posterior and medio-lateral directions), in two age groups on the basis of a systematic review and meta-analysis of available data published worldwide. After a systematic review of publications presenting values of selected CoP measures, a numerical database with means and standard deviations was created. Data were classified by eye condition (open or closed) and by age group (18-35 or ≥56)...
April 9, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29684662/release-of-endothelial-microparticles-in-patients-with-arterial-hypertension-hypertensive-emergencies-and-catheter-related-injury
#6
Roberto Sansone, Maximilian Baaken, Patrick Horn, Dominik Schuler, Ralf Westenfeld, Nicolas Amabile, Malte Kelm, Christian Heiss
BACKGROUND AND AIMS: Circulating endothelial microparticles (EMPs) are increased in arterial hypertension. The role of physicomechanical factors that may induce EMP release in vivo is still unknown. We studied the relationship of EMPs and physicomechanical factors in stable arterial hypertension and hypertensive emergencies, and investigated the pattern of EMP release after mechanical endothelial injury. METHODS: In a pilot study, 41 subjects (50% hypertensives) were recruited...
April 12, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29684589/hydrogen-sulfide-donor-nahs-stimulates-anp-secretion-via-the-k-atp-channel-and-the-nos-sgc-pathway-in-rat-atria
#7
Lamei Yu, Byung Mun Park, Yong Jin Ahn, Gi-Ja Lee, Suhn Hee Kim
Hydrogen sulfide (H2 S) is normally produced from L-cysteine in mammalian tissues and related to the pathogenesis of cardiovascular diseases. The aim of this study is to investigate the effects of H2 S donor on atrial natriuretic peptide (ANP) secretion and define its mechanism using normal and isoproterenol (ISP)-treated rats. Several H2 S donors were perfused into isolated beating rat atria, and atrial pressure (AP) and ANP secretion were measured. NaHS augmented high stretch-induced ANP secretion and decreased AP in a dose-dependent manner...
April 20, 2018: Peptides
https://www.readbyqxmd.com/read/29684535/sodium-caprate-enables-the-blood-pressure-lowering-effect-of-ile-pro-pro-and-leu-lys-pro-in-spontaneously-hypertensive-rats-by-indirectly-overcoming-pept1-inhibition
#8
John P Gleeson, Jesús M Frías, Sinéad M Ryan, David J Brayden
The tripeptides, Ile-Pro-Pro (IPP) and Leu-Lys-Pro (LKP), inhibit angiotensin-converting enzyme (ACE) resulting in lowered blood pressure. Our hypothesis was that the medium chain fatty acid permeation enhancer, sodium caprate (C10 ), may prevent the decrease in permeability of the tripeptides when PepT1 is inhibited by glycyl-sarcosine (Gly-Sar), a situation that may occur in the presence of food hydrolysates. Using Caco-2 monolayers and isolated rat jejunal tissue, the apparent permeability coefficients (Papp ) of [3 H]-IPP and [3 H]-LKP were assessed in the presence of Gly-Sar with and without C10 ...
April 20, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29684516/reconsideration-of-neurogenic-pulmonary-oedema-as-a-source-of-metastatic-cerebral-abscess-following-subarachnoid-hemorrhages-a-preliminary-study
#9
Ahmet Gökyar, Mehmet D Aydın, Sevilay Özmen, Elif Demirci, Abdullah H Marangoz, Enis Kuruoğlu, Cengiz Çokluk
BACKGROUND: Subarachnoid hemorrhage (SAH) may be a cause of neurogenic pulmonary edema (NPE). It is well known that lymphatic fluid draining by thoracic duct to lungs consists of many dangerous metabolites, degraded tissue particles and microbiological pathogens. However, there is no enough study which investigates if NPE cause septicemia or not. In this study, we retrospectively examined our experimental materials whether there is a meaningful relationship between the NPE and cerebral abscess formation...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29684444/studies-into-slo1-k-channels-and-their-ligand-docosahexaenoic-acid-in-murine-sepsis-to-delineate-off-target-effects-of-immunonutrition
#10
Bianka Wissuwa, Stefan H Heinemann, Michael Bauer, Sina M Coldewey
AIMS: Studies on omega-3 fatty acids, including docosahexaenoic acid (DHA), reveal diverging results: Their intake is recommended in cardiovascular disease and major surgery, while evidence argues against use in septic patients. DHA mediates its blood-pressure-lowering effect through Slo1 channels that are expressed on cardiovascular and immune cells. We hypothesised that conflicting effects of immunonutrition could be explained by the influence of omega-3 fatty acids on systemic blood pressure or immune effector cells through Slo1...
April 20, 2018: Life Sciences
https://www.readbyqxmd.com/read/29684437/sleep-dysfunction-following-neonatal-ischemic-seizures-are-differential-by-neonatal-age-of-insult-as-determined-by-qeeg-in-a-mouse-model
#11
S K Kang, S Ammanuel, S Thodupunuri, D A Adler, M V Johnston, S D Kadam
Neonatal seizures associated with hypoxic-ischemic encephalopathy (HIE) pose a challenge in their acute clinical management and are often followed by long-term neurological consequences. We used a newly characterized CD-1 mouse model of neonatal ischemic seizures associated with age-dependent (P7 vs. P10) seizure severity and phenobarbital efficacy (i.e.; PB-resistant vs. PB-efficacious respectively) following unilateral carotid ligation. The long-term consequences following untreated neonatal seizures in P7 vs...
April 20, 2018: Neurobiology of Disease
https://www.readbyqxmd.com/read/29684414/examining-variability-in-parent-feeding-practices-within-a-low-income-racially-ethnically-diverse-and-immigrant-population-using-ecological-momentary-assessment
#12
Jerica M Berge, Allan Tate, Amanda Trofholz, Katie Loth, Michael Miner, Scott Crow, Dianne Neumark-Sztainer
BACKGROUND: Current measures of parent feeding practices are typically survey-based and assessed as static/unchanging characteristics, failing to account for fluctuations in these behaviors across time and context. The current study uses ecological momentary assessment to examine variability of, and predictors of parent feeding practices within a low-income, racially/ethnically diverse, and immigrant sample. METHODS: Children ages 5-7 years old and their parents (n = 150 dyads) from six racial/ethnic groups (n = 25 from each; Black/African American, Hispanic, Hmong, Native American, Somali, White) were recruited for this mixed-methods study through primary care clinics...
April 20, 2018: Appetite
https://www.readbyqxmd.com/read/29684371/repair-of-ductus-or-hemi-truncus-to-one-lung-and-major-aortopulmonary-collaterals-to-the-other-lung
#13
Richard D Mainwaring, Tatiana R Rosenblatt, William L Patrick, Michael Ma, Lynn Peng, Frank L Hanley
BACKGROUND: There are patients born with pulmonary atresia and a ductus arteriosus or hemi-truncus to one lung and major aortopulmonary collateral arteries (MAPCAs) to the contralateral lung. The purpose of this study was to review our surgical results for this relatively rare subset of patients. METHODS: This was a retrospective review of 35 patients with ductus/hemi-truncus in association with pulmonary atresia with ventricular septal defect and MAPCAs. Our surgical algorithm is bifurcated into two strategies: 1) patients with "favorable" MAPCAs are candidates for single stage complete repair, and 2) patients with "unfavorable" MAPCAs undergo a staged approach...
April 20, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29684325/the-effect-of-isochoric-freezing-on-mammalian-cells-in-an-extracellular-phosphate-buffered-solution
#14
J Preciado, B Rubinsky
Isochoric (constant volume) freezing has been recently suggested as a new method for cell and organ preservation. As a first step in studying the effect of isochoric freezing on mammalian cells, Madin-Darby canine kidney epithelial cells (MDCK), were frozen in an isochoric system, in a simple extracellular phosphate buffered solution to -10 °C (96.5 MPa), - 15 °C (162 MPa) and -20 °C (205 MPa) for 60 and 120 min. Cell membrane integrity and cell metabolism were studied with a Live/Dead cell vitality assay and flow cytometry...
April 20, 2018: Cryobiology
https://www.readbyqxmd.com/read/29684319/lipid-accumulation-product-index-in-hiv-infected-patients-a-marker-of-cardiovascular-risk
#15
Milena Maria Moreira Guimarães, Dirceu Bartolomeu Greco, Allyson Nogueira Moreira, Nathalia Sernizon Guimarães, Cláudia Maria Vilas Freire, Bruna Guimarães Rolfs, Lucas José de Campos Machado
The lipid accumulation product (LAP) index is an emerging cardiovascular risk marker. We aimed to assess the accuracy of this index as a marker of cardiovascular risk in HIV-infected patients. A cross-sectional study of 133 HIV-infected patients on antiretroviral drugs and 20 non-infected controls was conducted at the outpatient clinic of a referral center of infectious and parasitic diseases. Evaluations included LAP index, homeostasis model assessment (HOMA) index, anthropometric measurements, blood pressure, glucose tolerance test, and cholesterol and triglyceride levels...
April 20, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29684316/continuous-positive-airway-pressure-adherence-predictors-in-a-randomized-controlled-trial-enriched-with-women-and-minorities
#16
Anna M May, Tarek Gharibeh, Lu Wang, Amanda Hurley, Harneet Walia, Kingman P Strohl, Reena Mehra
BACKGROUND: Suboptimal continuous positive airway pressure (CPAP) adherence in obstructive sleep apnea (OSA) clinical trials involving predominantly Caucasian males limits interpretability and generalizability. We examined predictors of CPAP adherence in a clinical trial enriched with minorities. METHODS: The Sleep Apnea Stress Study - a randomized double-blind, sham-controlled trial of moderate-severe OSA patients - included participants with complete 8-week adherence data (n=138)...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29684315/sleep-disorders-in-patients-with-post-traumatic-stress-disorder
#17
REVIEW
Ali A El-Solh, Usman Riaz, Jasmine Roberts
A growing body of evidence supports a bidirectional relationship between post-traumatic stress disorder (PTSD) and sleep disturbances. Fragmented sleep induced by sleep-related breathing disorders, insomnia, and nightmares impacts recovery and treatment outcomes and worsens PTSD symptoms. Despite recent attention, management of these disorders has been unrewarding in the setting of PTSD. This review summarizes the evidence for empirically supported treatments of these sleep ailments as it relates to PTSD including psychotherapeutic and pharmacologic interventions...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29684306/does-sphenopalatine-ganglion-block-improve-pain-control-and-intraoperative-hemodynamics-in-children-undergoing-palatoplasty-a-randomized-controlled-trial
#18
Anantanarayanan Parameswaran, Muruganand V Ganeshmurthy, Yashoda Ashok, Manikandhan Ramanathan, Anthony F Markus, Hermann F Sailer
PURPOSE: Children undergoing cleft palate repair have pain, dysphagia, and wound irritation in the immediate postoperative phase that may compromise surgical outcomes. This trial evaluates the efficacy of the sphenopalatine ganglion block (SPGB) in optimizing intraoperative hemodynamics and postoperative analgesia in children undergoing primary palatoplasty. MATERIALS AND METHODS: The study was designed as a prospective, double-blind, randomized controlled trial comparing the use of SPGB with general anesthesia (GA) (study group) versus the use of only GA (control group)...
March 30, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29684292/elevated-blood-pressure-and-its-predictors-among-secondary-school-students-in-sarawak-a-cross-sectional-study
#19
Woei Feng Grace Kho, Whye Lian Cheah, Helmy Hazmi
OBJECTIVES: Hypertension is a health issue affecting adolescents. Accumulating evidence affirms that elevated blood pressure begins in childhood and tracks into adulthood. This cross-sectional study was conducted to determine the prevalence of elevated blood pressure and its predictors among secondary school students in Sarawak, Malaysia. METHODS: A total of 2,461 secondary school students aged 12-17 years from 19 schools in Sarawak participated in the study. Questionnaire was used to obtain socio-demographic data, parental history of hypertension, and self-reported physical activity...
March 2018: Central European Journal of Public Health
https://www.readbyqxmd.com/read/29684267/evaporation-study-of-ionic-liquid-with-double-charged-cation
#20
Norbert S Chilingarov, Maksim S Zhirov, Anna M Shmykova, Ekaterina A Martynova, Lev M Glukhov, Elena A Chernikova, Leonid M Kustov, Vitaliy Yu Markov, Vitaliy A Ioutsi, Lev Nikolaevich Sidorov
The evaporation of dicationic ionic liquid, 1,3-bis(3-methylimidazolium-1-yl)propane bis(trifluoromethanesulfonyl)amide ([C3 (MIm)22+ ][Tf2 N- ]2 ), was studied by Knudsen effusion mass spectrometry. Its evaporation is accompanied by a partial thermal decomposition producing monocationic ionic liquids, 1,3-dimethylimidazolium and 1-(2-propenyl)-3-methylimidazolium bis(trifluoromethanesulfonyl)amides, as volatile products. This decomposition does not affect the vaporization characteristics of [C3 (MIm)2 2+ ][Tf2 N- ]2 , which were established to be as follows...
April 23, 2018: Journal of Physical Chemistry. A
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