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https://www.readbyqxmd.com/read/29028864/predicting-cognitive-functioning-activities-of-daily-living-and-participation-6-months-after-mild-to-moderate-stroke
#1
Madison Bertolin, Ryan Van Patten, Taylor Greif, Robert Fucetola
Objective: Predicting neurocognitive and functional outcomes in stroke is an important clinical task, especially in rehabilitation settings. We assessed acute predictors of cognitive and functional outcomes 6 months after mild to moderate stroke. Methods: We conducted a retrospective analysis of acute clinical data and 6-month follow-up telephone interviews for 498 mild to moderate stroke patients. Predictors were sociodemographic variables, the National Institute of Health Stroke Scale (NIHSS), basic physical measures, the Mesulam Cancellation Test, the Short Blessed Test (SBT), Trails A/B, and the Boston Naming Test...
September 25, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29026789/the-impact-of-the-predictive-nursing-education-process-on-degree-of-comfort-and-quality-of-life-for-patients-in-the-oncology-department
#2
Yan Yu, Lijuan Hu, Xingu Chen, Mei Ge, Huijuan Zhu, Yusheng Yan
BACKGROUND: We investigated the application of a predictive nursing education process on the degree of comfort and quality of life for cancer patients. METHODS: A total of 168-cancer patient in Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China between June 2014 and June 2016 were enrolled and admitted for surgery or radiotherapy/chemotherapy treatment. Patients were randomly divided into control and observation groups, each containing 84 cases...
September 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29024289/diastereoselective-c-h-bond-amination-for-disubstituted-pyrrolidines
#3
Theodore Alexander Betley, Diana A Iovan, Matthew J T Wilding, Elisabeth T Hennessy, Yunjung Baek
We report herein on the improved diastereoselective synthesis of 2,5-disubstituted pyrrolidines from aliphatic azides. Experimental and theoretical studies of the C-H amination reaction mediated by the iron dipyrrinato complex (AdL)FeCl(OEt2) provided a model for diastereoinduction and allowed for systematic variation of the catalyst to enhance selectivity. Among the iron alkoxide and aryloxide catalysts evaluated, the iron-phenoxide complex exhibited superior performance towards the generation of syn 2,5-disubstituted pyrrolidines with high diastereoselectivity...
October 12, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29021442/the-relationship-between-the-serum-oxytocin-levels-disease-activity-the-adls-and-the-qol-in-patients-with-rheumatoid-arthritis
#4
Yusuke Miwa, Hidekazu Furuya, Ryo Yanai, Tsuyoshi Kasama, Kenji Sanada
Objective To investigate the factors associated with depression, including the serum oxytocin (OXT) levels, disease activity, activities of daily living (ADLs) and quality of life (QOL), and their effects on rheumatoid arthritis (RA). Methods This study included 42-RA-patients. We measured the following variables before and after 6 months of treatment with biological disease-modifying anti rheumatic drugs (bDMARDs): the baseline characteristics (including age, sex, disease duration, smoking, and body mass index), the doses of prednisolone and methotrexate, the serum level of matrix metalloprotease-3, the erythrocyte sedimentation rate and the C-reactive protein level...
October 11, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29019939/creating-affording-situations-coaching-through-animate-objects
#5
Chris Baber, Ahmad Khattab, Martin Russell, Joachim Hermsdörfer, Alan Wing
We explore the ways in which animate objects can be used to cue actions as part of coaching in Activities of Daily Living (ADL). In this case, changing the appearance or behavior of a physical object is intended to cue actions which are appropriate for a given context. The context is defined by the intention of the users, the state of the objects and the tasks for which these objects can be used. We present initial design prototypes and simple user trials which explore the impact of different cues on activity...
October 11, 2017: Sensors
https://www.readbyqxmd.com/read/29017476/the-relationship-between-preoperative-american-society-of-anesthesiologists-physical-status-classification-scores-and-functional-recovery-following-hip-fracture-surgery
#6
Li-Huan Chen, Jersey Liang, Min-Chi Chen, Chi-Chuan Wu, Huey-Shinn Cheng, Hsiu-Ho Wang, Yea-Ing Lotus Shyu
BACKGROUND: Little is known about the relationship of the American Society of Anesthesiologists Physical Status Classification scores (ASA scores) on patient outcomes following hip fracture surgery in Asian countries. Therefore, this study explored the association of patients' preoperative ASA scores on trajectories of recovery in physical functioning and health outcomes during the first year following postoperative discharge for older adults with hip-fracture surgery in Taiwan. METHODS: The data for this study was generated from three prior studies...
October 10, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29016449/self-reported-decline-in-everyday-function-cognitive-symptoms-and-cognitive-function-in-people-with-hiv
#7
Rosanna Laverick, Lewis Haddow, Marina Daskalopoulou, Fiona Lampe, Richard Gilson, Andrew Speakman, Andrea Antinori, Tina Bruun, Anna Vassilenko, Simon Collins, Alison Rodger
BACKGROUND: We determined factors associated with self-reported decline in activities of daily living (ADLs) and symptoms of cognitive impairment in HIV positive adults in 5 European clinics. METHODS: HIV+ adults underwent computerized and pen-and-paper neuropsychological tests and questionnaires of cognitive symptoms and ADLs. We considered cognitive function in 5 domains, psychosocial factors, and clinical parameters as potentially associated with symptoms. Separate regression analyses were used to determine factors associated with a decline in ADL (defined as self-reported decline affecting ≥2 ADLs and attributed to cognitive difficulties) and self-reported frequency of symptoms of cognitive impairment...
November 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28992770/influence-of-demographic-and-utilization-of-physical-therapy-interventions-on-clinical-outcomes-and-revision-rates-following-anterior-cruciate-ligament-reconstruction
#8
Caitlin J Miller, Jesse C Christensen, Ryan D Burns
Study Design Retrospective cohort from Intermountain Healthcare system Jan 2007-Dec 2014. Background Recent evolutions in healthcare delivery are putting physical therapists in the forefront to be more responsible for providing high-quality rehabilitation care within a more cost-effective manner. Studies investigating the association between physical therapy (PT) visit utilization and outcomes in vulnerable patient populations following anterior cruciate ligament reconstruction (ACLR) may provide useful insights...
October 9, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28991661/behavioral-and-affective-features-of-amyotrophic-lateral-sclerosis-patients
#9
Yasuyuki Ohta, Kota Sato, Mami Takemoto, Yoshiaki Takahashi, Ryuta Morihara, Yumiko Nakano, Keiichiro Tsunoda, Emi Nomura, Nozomi Hishikawa, Toru Yamashita, Koji Abe
Evaluating the cognitive and behavioral features in amyotrophic lateral sclerosis (ALS) patients is important for therapy and care. Fifty-seven ALS, 5 ALS with the behavioral variant of frontotemporal dementia (FTD) (ALS-FTD), 12 FTD patients, and 35 control subjects were evaluated by 10 different tests for cognitive and behavioral (mini-mental state examination (MMSE), Hasegawa dementia rating scale - revised (HDS-R), frontal assessment battery (FAB), Montreal cognitive assessment (MoCA), ALS-frontotemporal dementia-Questionnaire (ALS-FTD-Q), and anosognosia scale), affective (depression, apathy, and behavioral and psychological symptoms of dementia (BPSD)), and activities of daily living (ADL) assessments...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28990881/fear-of-falling-restricts-activities-of-daily-living-after-total-hip-arthroplasty-a-one-year-longitudinal-study
#10
Koutatsu Nagai, Hisashi Ikutomo, Keiichi Tagomori, Namika Miura, Tadao Tsuboyama, Kensaku Masuhara
OBJECTIVES: To determine the prevalence and time course in changes regarding the fear of falling and whether there are consequent restrictions in activities of daily living (ADL) after total hip arthroplasty (THA). METHODS: This is 1-year longitudinal observational study. We recruited ninety-eight patients before and after THA. Fear of falling was assessed for 12 ADLs preoperatively and postoperatively at 3, 6, and 12 months following THA. In addition, we asked patients to answer whether they had refrained from performing each ADL because of fear of falling...
August 11, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/28988862/early-pheromone-experience-modifies-a-synaptic-activity-to-influence-adult-pheromone-responses-of-c-%C3%A2-elegans
#11
Myeongjin Hong, Leesun Ryu, Maria C Ow, Jinmahn Kim, A Reum Je, Satya Chinta, Yang Hoon Huh, Kea Joo Lee, Rebecca A Butcher, Hongsoo Choi, Piali Sengupta, Sarah E Hall, Kyuhyung Kim
Experiences during early development can influence neuronal functions and modulate adult behaviors [1, 2]. However, the molecular mechanisms underlying the long-term behavioral effects of these early experiences are not fully understood. The C. elegans ascr#3 (asc-ΔC9; C9) pheromone triggers avoidance behavior in adult hermaphrodites [3-7]. Here, we show that hermaphrodites that are briefly exposed to ascr#3 immediately after birth exhibit increased ascr#3-specific avoidance as adults, indicating that ascr#3-experienced animals form a long-lasting memory or imprint of this early ascr#3 exposure [8]...
October 4, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28988219/differences-in-levels-of-albumin-alt-ast-%C3%AE-gt-and-creatinine-in-frail-moderately-healthy-and-healthy-elderly-individuals
#12
Maria Edvardsson, Märtha Sund-Levander, Anna Milberg, Ewa Wressle, Jan Marcusson, Ewa Grodzinsky
BACKGROUND: Reference intervals are widely used as decision tools, providing the physician with information about whether the analyte values indicate ongoing disease process. Reference intervals are generally based on individuals without diagnosed diseases or use of medication, which often excludes elderly. The aim of the study was to assess levels of albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine and γ-glutamyl transferase (γ-GT) in frail, moderately healthy and healthy elderly indivuduals...
October 9, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28987469/prevalence-of-sarcopenia-and-its-association-with-activities-of-daily-living-and-dysphagia-in-convalescent-rehabilitation-ward-inpatients
#13
Yoshihiro Yoshimura, Hidetaka Wakabayashi, Takahiro Bise, Maiko Tanoue
BACKGROUND: The purpose of this study was to investigate the prevalence of sarcopenia following stroke, musculoskeletal disease, or hospital-associated deconditioning in convalescent rehabilitation ward inpatients. The association between the activities of daily living (ADLs), dysphagia, and sarcopenia was also assessed. METHODS: A cross-sectional study was performed in consecutive patients admitted to convalescent rehabilitation wards. Sarcopenia was defined as a loss of skeletal muscle mass and decreased muscle strength...
September 23, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28987191/developmental-and-perinatal-brain-diseases
#14
Homa Adle-Biassette, Jeffery A Golden, Brian Harding
This chapter briefly describes the normal development of the nervous system, the neuropathology and pathophysiology of acquired and secondary disorders affecting the embryo, fetus, and child. They include CNS manifestations of chromosomal change; forebrain patterning defects; disorders of the brain size; cell migration and specification disorders; cerebellum, hindbrain and spinal patterning defects; hydrocephalus; secondary malformations and destructive pathologies; vascular malformations; arachnoid cysts and infectious diseases...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28986942/management-of-behavioral-and-psychological-symptoms-of-dementia-bpsd-by-an-aroma-massage-with-acupressure-treatment-protocol-a-randomized-clinical-trial
#15
Jo Kamen Ka-Man Fung, Hector Wing-Hong Tsang
AIMS AND OBJECTIVES: This study evaluates the clinical effectiveness of a multi-component aroma-massage with an acupressure treatment protocol and compared it to cognitive training for the management of BPSD. BACKGROUND: Pharmacological interventions have been unsatisfactory in managing BPSD; thus, complementary and alternative medicine has been extensively researched to identify an adjunct safe and cost-effective intervention. DESIGN: This RCT utilized a three-arm parallel group design...
October 6, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28986228/application-of-gelatin-sponge-impregnated-with-a-mixture-of-three-drugs-to-intraoperative-nerve-root-block-combined-with-robot-assisted-mis-tlif-surgery-in-the-treatment-of-adult-degenerative-scoliosis-a-clinical-observation-from-96-patients
#16
Jin Peng Du, Yong Fan, Ji Jun Liu, Jia Nan Zhang, Shi Chang Liu, Dingjun Hao
BACKGROUND: Application of nerve root block mainly for the diagnosis. However, less application in intraoperative treatment. OBJECTIVE: To observe clinical and imaging outcomes of application of gelatin sponge impregnated a mixture of three drugs (GSIAM) to intraoperative nerve root block combined with robot-assisted MIS-TLIF (RA-MIS-TLIF) surgery in the treatment of adult degenerative lumbar scoliosis (ADLS). METHODS: From January 2012 to November 2014, 108 patients with ADLS have been treated with RA-MIS-TLIF surgery combined with intraoperative GSIAM...
October 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28984597/cognitive-change-in-rehabilitation-patients-with-dementia-prevalence-and-association-with-rehabilitation-success
#17
Ilona Dutzi, Michael Schwenk, Marietta Kirchner, Jürgen M Bauer, Klaus Hauer
BACKGROUND: Dementia is a frequent diagnosis in geriatric rehabilitation. Studies in patients with dementia on the development of their cognitive status during rehabilitation and its relation to functional outcomes have been scarce. OBJECTIVES: To describe the changes in cognitive status in patients with dementia during inpatient rehabilitation and to determine its association with patient characteristics and rehabilitation outcome. METHODS: Cohort study in a geriatric rehabilitation center with data collection at admission and discharge...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28984092/patterns-of-changes-in-functional-and-neurocognitive-status-in-elderly-patients-after-transcatheter-vs-surgical-aortic-valve-replacements
#18
Marta Załęska-Kocięcka, Anna Skrobisz, Sebastian Woźniak, Lidia Greszata, Maciej Dąbrowski, Maciej Grabowski, Katarzyna Piotrowska, Anna Konopka, Marek Banaszewski, Anna Mierzynska
BACKGROUND: Replacement of severely stenotic aortic valve may influence cognitive and physical functioning. The aim of this study was to compare cognitive and functional status after surgical (SAVR) vs transcatheter aortic valve replacements (TAVR) in the elderly with severe aortic stenosis (AS). METHODS: It was a prospective observational study with over 6 months of follow-up. Eighty ≥70-year-old patients with AS underwent TAVR (n=40) or SAVR (n=40). Mini Mental State Exam (MMSE), Activities Daily Living (ADL) score and Instrumental Activities Daily Living (IADL) score were used to assess the cognitive status, fundamental functioning and complex independent living skills, respectively...
October 4, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28983385/can-geriatric-psychiatry-patients-complete-symptoms-self-reports-using-tablets-a-randomized-study
#19
Ghizlane Moussaoui, Ching Yu, Vincent Laliberté, Dominique Elie, Artin A Mahdanian, Benjamin Dawson, Marilyn Segal, Karl J Looper, Rej Soham
BACKGROUND: With our aging population and limited number of geriatric psychiatrists, innovations must be made in order to meet the growing demands for geriatric psychiatry services. Emerging technologies could greatly improve access to care and systematic data collection. METHODS: This randomized study compared completion rates and time to completion (primary outcomes) when using iPad technology vs. traditional paper forms to complete self-report psychiatric symptoms...
September 2017: Canadian Geriatrics Journal: CGJ
https://www.readbyqxmd.com/read/28978831/treatment-of-elderly-patients-with-acute-myeloid-leukemia
#20
Tomonori Nakazato
Most patients diagnosed with acute myeloid leukemia (AML) are over the age of 60 years yet optimal treatment strategies for older adults remain unclear. Old age is associated with increased risk of treatment-related toxicity and worse survival compared to younger adults. It is widely recognized that chronological age does not capture the heterogeneous physiological and functional status of older adults. Thus, it is critically important to evaluate both disease-related (adverse cytogenetics, unfavorable gene mutations, secondary AML, etc...
2017: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
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