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https://www.readbyqxmd.com/read/29457559/functional-outcomes-of-inpatient-rehabilitation-in-very-elderly-patients-with-stroke-differences-across-three-age-groups
#1
Hitoshi Mutai, Tomomi Furukawa, Ayumi Wakabayashi, Akihito Suzuki, Tokiji Hanihara
Background As the population continues to age rapidly, clarifying the factors affecting the prognosis in very elderly stroke patients is essential to enhance the quality of their rehabilitation. Objectives To compare the functional recovery of elderly stroke patients classified into three age groups and to identify the predictors of functional recovery in the very elderly following acute inpatient rehabilitation. Methods Observational study: We collected data on 461 stroke patients in the neurology and neurosurgery ward and classified them into three age groups (65-74, 75-84, and ≥ 85 years)...
February 19, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29457411/-effect-of-hip-fracture-at-different-sites-in-elderly-patients-on-prognosis
#2
Cheng Peng, Xiao-Wei Wang, Shao-Guang Li, Zhi Liu, Tian-Sheng Sun, Jian-Zheng Zhang
OBJECTIVE: To determine the effect of site of fracture on the prognosis for patients of elderly hip fracture. METHODS: From January 2012 to December 2014, 667 patients with hip fractures were divided into femoral neck fracture group and intertrochanteric fracture group according to the site of fracture. There were 304 cases of intertrochanteric fracture, including 96 males and 208 females, with an average age of (80.33±7.94) years old. There were 217 cases of femoral neck fracture, including 74 males and 143 females, with an average age of (79...
October 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29456067/revision-hip-arthroscopy-after-labral-reconstruction-using-iliotibial-band-autograft-surgical-findings-and-comparison-of-outcomes-with-labral-reconstructions-not-requiring-revision
#3
Renato Locks, Ioanna K Bolia, Hajime Utsunomiya, Karen K Briggs, Marc J Philippon
PURPOSE: To determine the causes of revision hip arthroscopy in patients who underwent labral reconstruction and to compare outcomes of these patients with patients who did not require a revision following reconstruction. METHODS: Patients who underwent revision hip arthroscopy after previous labral reconstruction from 2006 to 2014 were included. Patients with less than 2-year follow-up, preoperative joint space of ≤2 mm, or who underwent other reconstructive procedures at the time of labral reconstruction were excluded...
February 15, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29454973/comparison-of-dual-mobility-total-hip-arthroplasty-and-bipolar-arthroplasty-for-femoral-neck-fractures-a-retrospective-case-control-study-of-199-hips
#4
B Boukebous, P Boutroux, R Zahi, C Azmy, P Guillon
BACKGROUND: The choice between performing total hip arthroplasty (THA) or hemiarthroplasty (HA) is not straightforward in older patients with femoral neck fracture, particularly when co-morbidities are factored in. This led us to carry out a case-control study to determine 1) the rate of mechanical complications for these two types of implants, and 2) the rate of medical complications and mortality. HYPOTHESIS: THA with dual mobility cup (DM) will result in fewer mechanical complications than HA...
February 15, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29453585/predicting-hospital-length-of-stay-and-short-term-function-after-hip-or-knee-arthroplasty-are-both-performance-and-comorbidity-measures-useful
#5
Stéphane Poitras, Kendrick Au, Kristi Wood, Geoffrey Dervin, Paul E Beaulé
PURPOSE: Variations in hospital length of stay (LOS) and function are present after hip or knee arthroplasty. Comorbidity and performance measures have been associated with post-operative outcomes. It is however not known if both independently contribute to outcome prediction. The objective of this study was to evaluate the combined predictive ability of comorbidity scores (American Society of Anesthesiologists classification system (ASA), Charlson comorbidity index (CCI), 2008 version of the CCI (CCI08)) and a performance measure (Timed-Up-and-Go (TUG)) on LOS and short-term function in patients undergoing knee or hip arthroplasty...
February 17, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29452781/physical-training-maintains-or-improves-gait-ability-in-long-term-nursing-home-residents-a-systematic-review-of-randomized-controlled-trials
#6
REVIEW
Haritz Arrieta, Chloe Rezola-Pardo, Susana María Gil, Jon Irazusta, Ana Rodriguez-Larrad
Numerous studies have reported the benefits of physical exercise in older adults. However, studies performed in long-term nursing home (LTNH) residents are scarce. A literature search was conducted to identify physical exercise intervention studies that were randomized and controlled and that assessed gait ability in older LTNH residents using both walking speed and timed up-and-go (TUG) tests simultaneously. Together, these tests have been defined under the term "gait ability"; they are widely used to screen for impaired physical function, and can predict accelerated functional decline, difficulty with activities of daily living (ADL), falls, and disability in older adults...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29447350/soil-protists-a-fertile-frontier-in-soil-biology-research
#7
Stefan Geisen, Edward A D Mitchell, Sina Adl, Michael Bonkowski, Micah Dunthorn, Flemming Ekelund, Leonardo D Fernández, Alexandre Jousset, Valentyna Krashevska, David Singer, Frederick W Spiegel, Julia Walochnik, Enrique Lara
Protists include all eukaryotes except plants, fungi and animals. They are an essential, yet often forgotten, component of the soil microbiome. Method developments have now furthered our understanding of the real taxonomic and functional diversity of soil protists. They occupy key roles in microbial foodwebs as consumers of bacteria, fungi and other small eukaryotes. As parasites of plants, animals and even of larger protists, they regulate populations and shape communities. Pathogenic forms play a major role in public health issues as human parasites, or act as agricultural pests...
February 13, 2018: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/29447253/combined-impairments-in-vision-hearing-and-cognition-are-associated-with-greater-levels-of-functional-and-communication-difficulties-than-cognitive-impairment-alone-analysis-of-interrai-data-for-home-care-and-long-term-care-recipients-in-ontario
#8
Dawn M Guthrie, Jacob G S Davidson, Nicole Williams, Jennifer Campos, Kathleen Hunter, Paul Mick, Joseph B Orange, M Kathleen Pichora-Fuller, Natalie A Phillips, Marie Y Savundranayagam, Walter Wittich
OBJECTIVES: The objective of the current study was to understand the added effects of having a sensory impairment (vision and/or hearing impairment) in combination with cognitive impairment with respect to health-related outcomes among older adults (65+ years old) receiving home care or residing in a long-term care (LTC) facility in Ontario, Canada. METHODS: Cross-sectional analyses were conducted using existing data collected with one of two interRAI assessments, one for home care (n = 291,824) and one for LTC (n = 110,578)...
2018: PloS One
https://www.readbyqxmd.com/read/29443744/serum-levels-of-vitamin-a-and-25-hydroxyvitamin-d3-25ohd3-as-reflectors-of-pulmonary-function-and-quality-of-life-qol-in-children-with-stable-asthma-a-case-control-study
#9
Ya-Jie Bai, Ru-Jun Dai
BACKGROUND: This study aims to explore the relationship between serum vitamin A and 25-hydroxyvitamin D3 (25OHD3) levels with pulmonary function and quality of life (QOL) in children with stable asthma. METHODS: A total of 117 cases of children with stable asthma were assigned into the case group and 129 healthy children underwent physical examination during the same period into the control group. Electrochemiluminescence was employed to determine serum vitamin A and 25OHD3 levels...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29442577/high-rate-of-return-to-yoga-for-athletes-after-hip-arthroscopy-for-femoroacetabular-impingement-syndrome
#10
Rachel M Frank, Gift Ukwuani, Bradley Allison, Ian Clapp, Shane J Nho
BACKGROUND: Femoroacetabular impingement syndrome (FAIS) is most commonly diagnosed in patients who perform activities that require repetitive hip flexion and rotational loading. Yoga is an activity growing in popularity that involves these motions. The purpose of this study was to evaluate patients' ability to return to yoga after hip arthroscopy for FAIS. HYPOTHESIS: There would be a high rate of return to yoga after hip arthroscopy. STUDY DESIGN: Retrospective analysis...
February 1, 2018: Sports Health
https://www.readbyqxmd.com/read/29439358/improvement-in-activities-of-daily-living-after-visual-training-in-patients-with-homonymous-visual-field-defects-using-goal-attainment-scaling
#11
Joris A Elshout, Douwe P Bergsma, Jacqueline Sibbel, Annette Baars-Elsinga, Paula Lubbers, Freekje Van Asten, Johanna Visser-Meily, Albert V Van Den Berg
BACKGROUND: Stroke is the most common cause of homonymous visual field defects (HVFDs). Yet, there is no standard protocol for composing a rehabilitation program. OBJECTIVE: In this study we assess ADL gain of visual training for vision restoration in HVFD patients by means of Goal Attainment Scaling. METHODS: Thirty-five patients trained two predefined regions of the visual field successively at home. In each region we compared the effects of both training rounds, one of which was thus 'directed' and the other 'undirected'...
2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29438659/what-factors-are-associated-with-the-recovery-of-autonomy-after-a-hip-fracture-a-prospective-multicentric-cohort-study
#12
Mattia Morri, Paolo Chiari, Cristiana Forni, Antonella Orlandi Magli, Domenica Gazineo, Natalia Franchini, Lorenzo Marconato, Tiziana Giamboi, Andrea Cotti
OBJECTIVE: to identify the factors associated with recovering autonomy in the activities of daily living DESIGN: A prospective cohort study SETTING: The orthopedic and orthogeriatric departments of 2 regional hospitals PARTICIPANTS: Patients 65 years of age or older with a diagnosis of fragility hip fracture. There were 840 eligible patients. Forty-three patients were excluded and 55 were lost. Seven hundred and forty-two consecutive patients was enrolled at the time of hospitalization and 727 at follow-up...
February 10, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29438603/from-early-radiographic-knee-osteoarthritis-to-joint-arthroplasty-determinants-of-structural-progression-and-symptoms
#13
Frank W Roemer, C Kent Kwoh, Tomoko Fujii, Michael J Hannon, Robert M Boudreau, David J Hunter, Felix Eckstein, Markus R John, Ali Guermazi
OBJECTIVE: Aims were to assess (1) structural progression in knees with no/mild radiographic osteoarthritis (ROA) (i.e. Kellgren-Lawrence (K-L) grades 0 to 2) that will undergo knee replacement (KR) during a 5-year period; (2) differences in structural damage on MRI between knees with no/mild ROA vs. those with severe ROA (i.e. K-L 3 and 4) at baseline; and (3) differences in pain levels between those groups. METHODS: All participants who underwent KR from baseline (BL) to 60 months were drawn from the Osteoarthritis Initiative...
February 13, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29435915/eculizumab-a-review-in-generalized-myasthenia-gravis
#14
Sohita Dhillon
The humanized monoclonal antibody eculizumab (Soliris ® ) is a complement inhibitor indicated for use in anti-acetylcholine receptor (AChR) antibody-positive adults with generalized myasthenia gravis (gMG) in the USA, refractory gMG in the EU, or gMG with symptoms that are difficult to control with high-dose IVIg therapy or PLEX in Japan. It is the first complement inhibitor to be approved for use in these patients. In the well-designed, 26-week REGAIN study in patients with anti-AChR-positive refractory gMG, although a statistically significant benefit of eculizumab over placebo in the prespecified primary endpoint analysis (change from baseline in MG-activities of daily living (ADL) score assessed by worst-rank ANCOVA) was not formally demonstrated, preplanned and post hoc sensitivity analyses of this outcome, as well as other secondary outcomes supported the efficacy of eculizumab...
February 12, 2018: Drugs
https://www.readbyqxmd.com/read/29434777/effects-of-donepezil-on-cognitive-functions-and-the-expression-level-of-%C3%AE-amyloid-in-peripheral-blood-of-patients-with-alzheimer-s-disease
#15
Yunxia Ma, Jinming Ji, Gang Li, Shuzhen Yang, Shuangshuang Pan
Alzheimer's disease is a degenerative disease affecting the central nervous system for which donepezil is usually prescribed. The aim of the present study was to examine the effects of donepezil on the cognitive functions and expression levels of β-amyloid (Aβ) in the peripheral blood of patients with Alzheimer's disease. In total, 76 patients with cognitive impairment, who visited the Department of Neurology of Binzhou City Center Hospital from June 2015 to September 2016, had memory decline for more than three consecutive months and underwent mini-mental state examination (MMSE) score screening, were selected for the study...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29434257/broadband-imaging-with-one-planar-diffractive-lens
#16
Nabil Mohammad, Monjurul Meem, Bing Shen, Peng Wang, Rajesh Menon
We demonstrate imaging over the visible band using a single planar diffractive lens. This is enabled via multi-level diffractive optics that is designed to focus over a broad wavelength range, which we refer to as an achromatic diffractive lens (ADL). We designed, fabricated and characterized two ADLs with numerical apertures of 0.05 and 0.18. Diffraction-limited focusing is demonstrated for the NA = 0.05 lens with measured focusing efficiency of over 40% across the entire visible spectrum (450 nm to 750 nm)...
February 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29433008/molecular-characterization-of-the-vitamin-d-receptor-vdr-gene-in-holstein-cows
#17
Mayar O Ali, Mohamed A El-Adl, Hussam M M Ibrahim, Youssef Y Elseedy, Mohamed A Rizk, Sabry A El-Khodery
Vitamin D plays a vital role in calcium homeostasis, growth, and immunoregulation. Because little is known about the vitamin D receptor (VDR) gene in cattle, the aim of the present investigation was to present the molecular characterization of exons 5 and 6 of the VDR gene in Holstein cows. DNA extraction, genomic sequencing, phylogenetic analysis, synteny mapping and single nucleotide gene polymorphism analysis of the VDR gene were performed to assess blood samples collected from 50 clinically healthy Holstein cows...
February 5, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29429623/2nd-international-workshop-on-spinal-loading-and-deformation
#18
EDITORIAL
Aboulfazl Shirazi-Adl, Hendrik Schmidt, Idsart Kingma
No abstract text is available yet for this article.
February 3, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29429373/long-term-clinical-and-mri-results-of-matrix-assisted-autologous-chondrocyte-implantation-for-articular-cartilage-defects-of-the-knee
#19
Peter Cornelius Kreuz, Richard Horst Kalkreuth, Philipp Niemeyer, Markus Uhl, Christoph Erggelet
Objective To evaluate the long-term clinical and radiological outcome of matrix-assisted autologous chondrocyte implantation (mACI) for articular cartilage defects in the knee joint. Design Clinical evaluation was assessed in 21 patients with full-thickness cartilage defects, International Cartilage Repair Society (ICRS) grade IV. Clinical scoring was performed preoperatively and 12 years after transplantation using the International Knee Documentation Committee (IKDC) score, the Lysholm score, the Knee injury and Osteoarthritis Outcome Score (KOOS), and the Noyes sports activity rating scale...
February 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29426606/symptomatic-and-functional-recovery-from-major-depressive-disorder-in-the-ibadan-study-of-ageing
#20
Akin Ojagbemi, Taiwo Abiona, Zhehui Luo, Oye Gureje
OBJECTIVES: Very little is known about the association between symptomatic and functional recovery from late-life major depressive disorder (MDD) in sub-Saharan Africa. We investigated factors associated with sustained symptomatic remission (SR) from MDD and the 5-year trajectory of post-MDD physical functioning. DESIGN: 5-year prospective study with three follow-up waves in 2007, 2008, and 2009. SETTING/PARTICIPANTS: Household multistage probability sample of 2,149 Nigerians who were aged 65 years or older...
January 4, 2018: American Journal of Geriatric Psychiatry
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