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https://www.readbyqxmd.com/read/28330581/functional-decline-in-older-patients-with-cancer-receiving-chemotherapy-a-multicenter-prospective-study
#1
Cindy Kenis, Lore Decoster, Julie Bastin, Hannelore Bode, Katrien Van Puyvelde, Jacques De Grève, Godelieve Conings, Katleen Fagard, Johan Flamaing, Koen Milisen, Jean-Pierre Lobelle, Hans Wildiers
OBJECTIVES: This study aims to evaluate the evolution of functional status (FS) 2 to 3months after initiation of chemotherapy, to identify factors associated with functional decline during chemotherapy treatment and to investigate the prognostic value of functional decline for overall survival (OS). PATIENTS AND METHODS: Patients ≥70years with a malignant tumor were included when chemotherapy was initiated. All patients underwent a geriatric assessment (GA) including FS measured by Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL)...
March 15, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28330442/association-among-activities-of-daily-living-instrumental-activities-of-daily-living-and-health-related-quality-of-life-in-elderly-yi-ethnic-minority
#2
Lingyun Ran, Xiaodong Jiang, Baogang Li, Hongqian Kong, Mengqi Du, Xiaolan Wang, Hua Yu, Qin Liu
BACKGROUND: The health-related quality of life (HRQoL) of the elderly population of Yi ethnic minority, which is the seventh largest nationality in China, has been rarely reported. This study was designed to explore the HRQoL of the elderly Yi ethnicity and association between their HRQOL and functional abilities. METHODS: A total of 291 Yi ethnic residents were randomly recruited from 12 rural counties in Yunnan province and divided into different age groups. Local residents in Yunnan province and the elderly from Hangzhou were enrolled as controls...
March 22, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28329825/socioeconomic-status-and-physical-functioning-a-longitudinal-study-of-older-chinese-people
#3
Lei Yang, Hanna Konttinen, Pekka Martikainen, Karri Silventoinen
Objectives: We aimed to assess the longitudinal associations of socioeconomic status and physical functioning using a large population-based survey data in China. Method: We used four waves of the Chinese Longitudinal Healthy Longevity Survey (2002-2011). Physical functioning was assessed by activities of daily living (ADL) and instrumental activities of daily living (IADL) measures. Socioeconomic status was assessed using educational attainment, occupational status, household income, financial resources, and access to health services...
February 16, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28322633/predicting-use-of-nurse-care-coordination-by-older-adults-with-chronic-conditions
#4
Catherine E Vanderboom, Diane E Holland, Jay Mandrekar, Christine M Lohse, Stephanie G Witwer, Vicki L Hunt
To be effective, nurse care coordination must be targeted at individuals who will use the service. The purpose of this study was to identify variables that predicted use of care coordination by primary care patients. Data on the potential predictor variables were obtained from patient interviews, the electronic health record, and an administrative database of 178 adults eligible for care coordination. Use of care coordination was obtained from an administrative database. A multivariable logistic regression model was developed using a bootstrap sampling approach...
October 1, 2016: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28304306/the-progression-of-alzheimer-s-disease-are-fast-decliners-really-fast-a%C3%A2-four-year-follow-up
#5
Federica Barocco, Marco Spallazzi, Letizia Concari, Simona Gardini, Annalisa Pelosi, Paolo Caffarra
BACKGROUND: The rate of cognitive and functional decline in Alzheimer's disease (AD) changes across individuals. OBJECTIVES: Our purpose was to assess whether the concept of "fast decline" really fits its definition and whether cognitive and functional variables at onset can predict the progression of AD. METHODS: 324 AD patients were included. We retrospectively examined their Mini-Mental State Examination (MMSE) total score and sub-items, Activities of Daily Living (ADL), and Instrumental Activities of Daily Living (IADL) at baseline and every six months for a 4-year follow-up...
March 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28292646/follow-up-of-elderly-patients-with-urogenital-cancers-evaluation-of-geriatric-care-needs-and-related-actions
#6
Silvio Monfardini, Sara Morlino, Riccardo Valdagni, Mario Catanzaro, Ardit Tafa, Barbara Bortolato, Giovanni Petralia, Elisa Bonetto, Elisa Villa, Stefano Picozzi, Maria Cristina Locatelli, Giuseppe Galetti, Andrea Millul, Yasmin Albanese, Elisa Bianchi, Claudia Panzarino, Francesca Gerardi, Ettore Beghi
OBJECTIVES: To investigate a comprehensive geriatric assessment (CGA) with subsequent investigation of healthcare patterns in older patients with urological cancers undergoing initial surgery or radiotherapy, to verify the usefulness of the incorporation of geriatric principles in future care plans. MATERIAL AND METHODS: This is a prospective cohort study. From November 2011 to March 2015, CGA was offered to all patients aged 70+ years treated with radiotherapy or surgery at seven tertiary centers...
March 11, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28288563/is-independence-of-older-adults-safe-considering-the-risk-of-falls
#7
Dorota Talarska, Magdalena Strugała, Marlena Szewczyczak, Sławomir Tobis, Michał Michalak, Izabela Wróblewska, Katarzyna Wieczorowska-Tobis
BACKGROUND: Falls affect approx. 30% of elderly population per year. They cause major injuries and reduce independence of the older adults' functioning. The main objective of the study was to evaluate the degree of independence and find the fall risk factors in the study group. METHODS: The study included 506 - older adults. The study group included patients from GP clinics and members of two senior centers. The study duration was 12 months. Our study tools included EASY- Care Standard 2010 questionnaire, Abbreviated Mental Test Score (AMTS), Index Barthel, Instrumental Activities of Daily Living Scale (IADL), Geriatric Depression Scale (GDS), Timed Up and Go (TUG)...
March 14, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28287059/subjective-measures-of-health-and-all-cause-mortality-the-rotterdam-study
#8
A Sajjad, R L Freak-Poli, A Hofman, S J Roza, M A Ikram, H Tiemeier
BACKGROUND: Subjectively assessed health is related to mortality. Various subjective indicators of health have been studied, but it is unclear whether perceived physical functioning or mental health best accounts for the relation with mortality. METHOD: We studied the relation of subjective measures of health with all-cause mortality in 5538 participants of age 55 to 96 years at baseline from the Rotterdam Study. Various instruments of subjectively assessed health were used, that included basic activities of daily living (BADL), instrumental activities of daily living (IADL), quality of life (QoL), positive affect, somatic symptoms and negative affect...
March 13, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28277550/participation-of-iranian-cerebral-palsy-children-in-life-areas-a-systematic-review-article
#9
REVIEW
Marzieh Pashmdarfard, Malek Amini, Afsoon Hassani Mehraban
OBJECTIVE: Cerebral palsy (CP) is the most common cause of chronic disability that restricts participation in areas of occupations for children. The main aim of rehabilitation is enhancement of their clients for participation in occupations. The aim of this study was to overview of the factors influencing the participations of children with CP in Iran. MATERIALS & METHODS: A systematic, evidence-based process (Duffy 2005) was used. For data gathering electronic databases including Google scholar and Iranian and foreigner famous journals in the fields of pediatrics, were used...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/28276169/intergenerational-transfers-and-informal-care-for-disabled-elderly-persons-in-china-evidence-from-charls
#10
Xiaoting Liu, Bei Lu, Zhixin Feng
Aiming at 'ageing healthier and ageing better', a certain amount of high-quality informal care should be available for elderly persons with physical disability as formal care is barely accessible in China. The demographic transition and family structural changes have dramatically weakened traditional norms of filial piety and the structure of intergenerational transfers. This article employed nationwide representative data from the first wave (2011) of Chinese Health and Retirement Longitudinal Study (CHARLS) in order to identify the duration of informal care provision at home for frail elders (1122 in rural areas and 577 in urban areas, total 1699), measured in monthly hours, before estimating the associations between intergenerational transfers and the received time of informal care with Tobit Model analysis...
March 9, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28273043/frailty-and-inflammatory-markers-in-older-adults-with-cancer
#11
Tomohiro F Nishijima, Allison M Deal, Grant R Williams, Emily J Guerard, Kirsten A Nyrop, Hyman B Muss
We examined the associations between frailty and inflammatory markers, in particular neutrophil lymphocyte ratio (NLR), in elderly cancer patients. We conducted cross-sectional analyses of data derived from the Carolina Seniors Registry (CSR), a database of geriatric assessments (GA) in older adults (≧65 years) with cancer. We included patients in the CSR who had a GA and complete blood count test before initiation of therapy. The primary outcome was frailty, determined using the 36-item Carolina Frailty Index (CFI)...
March 8, 2017: Aging
https://www.readbyqxmd.com/read/28269622/toward-personalized-and-context-aware-prompting-for-smartphone-based-intervention
#12
Ramin Fallahzadeh, Samaneh Aminikhanghahi, Ashley Nichole Gibson, Diane J Cook
Intervention strategies can help individuals with cognitive impairment to increase adherence to instructions, independence, and activity engagement and reduce errors on everyday instrumental activities of daily living (IADLs) and caregiver burden. However, to be effective, intervention prompts should be given at a time that does not interrupt other important user activities and is more convenient. In this paper, we propose an intelligent personalized intervention system for smartphones. In our approach, we use context and activity awareness to time prompts when they will most likely be viewed and used...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28259179/evaluation-of-a-research-diagnostic-algorithm-for-dsm-5-neurocognitive-disorders-in-a-population-based-cohort-of-older-adults
#13
Ranmalee Eramudugolla, Moyra E Mortby, Perminder Sachdev, Chantal Meslin, Rajeev Kumar, Kaarin J Anstey
BACKGROUND: There is little information on the application and impact of revised criteria for diagnosing dementia and mild cognitive impairment (MCI), now termed major and mild neurocognitive disorders (NCDs) in the DSM-5. We evaluate a psychometric algorithm for diagnosing DSM-5 NCDs in a community-dwelling sample, and characterize the neuropsychological and functional profile of expert-diagnosed DSM-5 NCDs relative to DSM-IV dementia and International Working Group criteria for MCI...
March 4, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28253275/impact-of-frontal-white-matter-hyperintensity-on-instrumental-activities-of-daily-living-in-elderly-women-with-alzheimer-disease-and-amnestic-mild-cognitive-impairment
#14
Noriko Ogama, Takashi Sakurai, Toshiharu Nakai, Shumpei Niida, Naoki Saji, Kenji Toba, Hiroyuki Umegaki, Masafumi Kuzuya
BACKGROUND: Instrumental activities of daily living (IADL) start to decline during the progression of amnestic mild cognitive impairment (aMCI) to Alzheimer disease (AD). Cognitive and physical decline are involved in the loss of functional independence. However, little is known about AD-related neural change that leads to IADL impairment. The purpose of this study was to clarify the effects of regional white matter hyperintensity (WMH) on IADL impairment in persons with AD and aMCI. METHODS: The participants were 347 female subjects aged 65-85 years diagnosed with AD (n = 227), aMCI (n = 44) or normal cognition (n = 76)...
2017: PloS One
https://www.readbyqxmd.com/read/28244570/factors-affecting-functional-impairment-among-elderly-germans-results-of-a-longitudinal-study
#15
A Hajek, T Luck, C Brettschneider, T Posselt, C Lange, B Wiese, S Steinmann, S Weyerer, J Werle, M Pentzek, A Fuchs, J Stein, H Bickel, E Mösch, M Wagner, K Heser, W Maier, J M Scherer, S G Riedel-Heller, H-H König
OBJECTIVE: To investigate causal factors of functional impairment in old age in a longitudinal approach. DESIGN: A population-based prospective cohort study. SETTING: Elderly individuals were recruited via GP offices at six study centers in Germany. They were observed every 1.5 years over six waves. PARTICIPANTS: Three thousand two hundred fifty-six people aged 75 years and older at baseline. MEASUREMENTS: Functional impairment was quantified by the Lawton and Brody Instrumental Activities of Daily Living scale (IADL) and the Barthel-Index (BI)...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28244556/relationship-between-fear-of-falling-and-preceived-difficulty-with-grocery-shopping
#16
C S Johnson, K M McLeod
Fear of falling is associated with self-imposed restrictions of basic and instrumental activities of daily living (ADL/IADL), leading greater risk for functional decline and falls. The inability to independently grocery shop, a food-related IADL, negatively affects nutritional status and survival among seniors. Thus, this study examined the relationship between the fear of falling and difficulty with grocery shopping among seniors (n=98, mean age=82, 83% female), taking into account their functional capacity...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28236586/impaired-mobility-depressed-mood-cognitive-impairment-and-polypharmacy-are-independently-associated-with-disability-in-older-cancer-outpatients-the-prospective-physical-frailty-in-elderly-cancer-patients-pf-ec-cohort-study
#17
Frederic Pamoukdjian, Thomas Aparicio, Laurent Zelek, Marouane Boubaya, Philippe Caillet, Veronique François, Laure de Decker, Vincent Lévy, Georges Sebbane, Elena Paillaud
OBJECTIVE: To assess the prevalence of disability and the oncologic factors associated with disability in older outpatients with cancer. MATERIALS AND METHODS: The Physical Frailty in Elderly Cancer patients (PF-EC) study (France) is a prospective bicentric observational cohort study. Two hundred and ninety outpatients with cancer were included. A cross-sectional analysis of oncologic factors and geriatric variables associated with disability that were collected using a comprehensive geriatric assessment (CGA) was conducted...
February 21, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28227880/toward-personalized-and-context-aware-prompting-for-smartphone-based-intervention
#18
Ramin Fallahzadeh, Samaneh Aminikhanghahi, Ashley Nichole Gibson, Diane J Cook, Ramin Fallahzadeh, Samaneh Aminikhanghahi, Ashley Nichole Gibson, Diane J Cook, Ashley Nichole Gibson, Samaneh Aminikhanghahi, Ramin Fallahzadeh, Diane J Cook
Intervention strategies can help individuals with cognitive impairment to increase adherence to instructions, independence, and activity engagement and reduce errors on everyday instrumental activities of daily living (IADLs) and caregiver burden. However, to be effective, intervention prompts should be given at a time that does not interrupt other important user activities and is more convenient. In this paper, we propose an intelligent personalized intervention system for smartphones. In our approach, we use context and activity awareness to time prompts when they will most likely be viewed and used...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28223934/plasma-cystatin-c-and-high-density-lipoprotein-are-important-biomarkers-of-alzheimer-s-disease-and-vascular-dementia-a-cross-sectional-study
#19
Rui Wang, Zhaoyu Chen, Yongmei Fu, Xiaobo Wei, Jinchi Liao, Xu Liu, Bingjun He, Yunqi Xu, Jing Zou, Xiaoyan Yang, Ruihui Weng, Sheng Tan, Christopher McElroy, Kunlin Jin, Qing Wang
Objectives: Cystatin C (Cys C) and high-density lipoprotein (HDL) play critical roles in neurodegenerative diseases, such as dementia, Alzheimer's disease (AD) and vascular dementia (VaD). However, whether they can be used as reliable biomarkers to distinguish patients with dementia from healthy subjects and to determine disease severity remain largely unknown. Methods: We conducted a cross-sectional study to determine plasma Cys C and HDL levels of 88 patients with dementia (43 AD patients, 45 VaD patients) and 45 healthy age-matched controls...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28223787/comparing-the-predictive-accuracy-of-frailty-comorbidity-and-disability-for-mortality-a-1-year-follow-up-in-patients-hospitalized-in-geriatric-wards
#20
Martin Ritt, Julia Isabel Ritt, Cornel Christian Sieber, Karl-Günter Gaßmann
BACKGROUND: Studies evaluating and comparing the power of frailty, comorbidity, and disability instruments, together and in parallel, for predicting mortality are limited. OBJECTIVE: This study aimed to evaluate and compare the measures of frailty, comorbidity, and disability in predicting 1-year mortality in geriatric inpatients. DESIGN: Prospective cohort study. PATIENTS AND SETTING: A total of 307 inpatients aged ≥65 years in geriatric wards of a general hospital participated in the study...
2017: Clinical Interventions in Aging
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