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https://www.readbyqxmd.com/read/28808371/efficacy-of-osteopathic-manipulative-treatment-approach-in-the-patient-with-pulmonary-fibrosis-in-critical-care-outpatient-department
#1
Manu Goyal, Kanu Goyal, Kanimozhi Narkeesh, Asir John Samuel, Narkeesh Arumugam, Subhasish Chatterjee, Sorabh Sharma
The purpose of the present case study was to explore the efficacy of osteopathic manipulative treatment (OMT) in patient with pulmonary fibrosis (PF) in the critical care outpatient department. Here, we present a 48-year-old male case with breathlessness, increased frequency of defecation, and pain in and around the nape of neck with diagnosed pulmonary fibrosis. He scored 3 on a patient-reported modified Medical Research Council (mMRC) dyspnea scale. Osteopathic examination reveals multiple somatic findings across the chest and abdominal region and treated by OMT...
July 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28807646/elevated-renal-pelvic-pressures-during-pcnl-risks-higher-postoperative-pain-and-longer-hospital-stay
#2
Muhannad Alsyouf, Samuel Abourbih, Benjamin West, Herbert Hodgson, D Duane Baldwin
PURPOSE: Renal pelvic pressure (RPP) may vary during percutaneous nephrolithotomy (PCNL). The purpose of this study was to determine the relationship between endoscope caliber, renal pelvic pressure, hospital stay and postoperative pain. MATERIALS AND METHODS: A review of 20 PCNLs with ureteroscopic guidance and renal pelvic pressure monitoring was performed. The ureteroscope working channel was connected to a pressure transducer and utilized to determine RPP at baseline, when irrigating using a 26 Fr rigid nephroscope, a 16 Fr flexible nephroscope and during suction...
August 11, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28806471/limited-uptake-of-ulcerative-colitis-treat-to-target-recommendations-in-real-world-practice
#3
Robert V Bryant, Samuel P Costello, Scott Schoeman, Dharshan Sathananthan, Emma Knight, Su-Yin Lau, Mark N Schoeman, Reme Mountifield, Derrick Tee, Simon P L Travis, Jane M Andrews
BACKGROUND & AIMS: A 'Treat to Target' (T2T) approach has been proposed for ulcerative colitis (UC), with a target of combined clinical and endoscopic remission. The aim of the study was evaluate the extent to which proposed targets are achieved in real-world care, along with clinician perceptions and potential challenges. METHODS: A multicentre, retrospective, cross-sectional review of patients with UC attending outpatient services in South Australia was conducted...
August 14, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28803581/nutrition-facts-panel-use-is-associated-with-diet-quality-and-dietary-patterns-among-latinos-with-type-2-diabetes
#4
Grace Kollannoor-Samuel, Sofia Segura-Pérez, Fatma M Shebl, Nicola L Hawley, Grace Damio, Jyoti Chhabra, Sonia Vega-López, Maria Luz Fernandez, Rafael Pérez-Escamilla
OBJECTIVE: The study aims were to (i) identify determinants of Nutrition Facts Panel (NFP) use and (ii) describe the association between NFP use and dietary intake among Latinos with type 2 diabetes. DESIGN: Baseline cross-sectional data from a clinical trial were used to assess the association between NFP use and dietary intake. Diet was measured using two methods: (i) a diet quality score (the Healthy Eating Index-2010) derived from a single 24 h recall and (ii) dietary pattern (exploratory factor analyses) from an FFQ...
August 14, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28802672/congruence-between-patient-characteristics-and-interventions-may-partly-explain-medication-adherence-intervention-effectiveness-an-analysis-of-190-randomized-controlled-trials-from-a-cochrane-systematic-review
#5
REVIEW
Samuel S Allemann, Robby Nieuwlaat, Tamara Navarro, Brian Haynes, Kurt E Hersberger, Isabelle Arnet
BACKGROUND: Due to the negative outcomes of medication non-adherence, interventions to improve adherence have been the focus of countless studies. The congruence between adherence-related patient characteristics and interventions may partly explain the variability of effectiveness in medication adherence studies. In their latest update of a Cochrane review reporting inconsistent effects of adherence interventions, the authors offered access to their database for sub-analysis. We aimed to use this database to assess congruence between adherence-related patient characteristics and interventions and its association with intervention effects...
August 9, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28799876/melanoma-brain-metastasis-the-impact-of-stereotactic-radiosurgery-braf-mutational-status-and-targeted-and-or-immune-based-therapies-on-treatment-outcome
#6
Rupesh Kotecha, Jacob A Miller, Vyshak A Venur, Alireza M Mohammadi, Samuel T Chao, John H Suh, Gene H Barnett, Erin S Murphy, Pauline Funchain, Jennifer S Yu, Michael A Vogelbaum, Lilyana Angelov, Manmeet S Ahluwalia
OBJECTIVE The goal of this study was to investigate the impact of stereotactic radiosurgery (SRS), BRAF status, and targeted and immune-based therapies on the recurrence patterns and factors associated with overall survival (OS) among patients with melanoma brain metastasis (MBM). METHODS A total of 366 patients were treated for 1336 MBMs; a lesion-based analysis was performed on 793 SRS lesions. The BRAF status was available for 78 patients: 35 had BRAF (mut) and 43 had BRAF wild-type ( BRAF-WT) lesions. The Kaplan-Meier method evaluated unadjusted OS; cumulative incidence analysis determined the incidences of local failure (LF), distant failure, and radiation necrosis (RN), with death as a competing risk...
August 11, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28797872/the-diameter-of-single-bundle-hamstring-autograft-does-not-significantly-influence-revision-rate-or-clinical-outcomes-after-anterior-cruciate-ligament-reconstruction
#7
Gregory C Wernecke, Alex Constantinidis, Ian A Harris, Bradley G Seeto, Darren B Chen, Samuel J MacDessi
BACKGROUND: Anterior cruciate ligament (ACL) graft failure is a complication of ACL reconstruction (ALCR). Smaller autograft diameter may be a contributing factor. Our aim was to determine if hamstring autograft diameter influences graft rupture and patient-reported outcome scores. METHODS: This study included 786 consecutive patients undergoing primary, single bundle, autograft hamstring ACLR. The primary outcome was revision ACLR surgery. Secondary outcomes were patient reported International Knee Documentation Committee (IKDC) score, Knee Injury & Osteoarthritis Outcome Score (KOOS) and Tegner Activity score...
August 7, 2017: Knee
https://www.readbyqxmd.com/read/28793152/identification-of-characters-and-localization-of-images-using-direct-multiple-electrode-stimulation-with-a-suprachoroidal-retinal-prosthesis
#8
Mohit N Shivdasani, Nicholas C Sinclair, Lisa N Gillespie, Matthew A Petoe, Samuel A Titchener, James B Fallon, Thushara Perera, Darien Pardinas-Diaz, Nick M Barnes, Peter J Blamey
Purpose: Retinal prostheses provide vision to blind patients by eliciting phosphenes through electrical stimulation. This study explored whether character identification and image localization could be achieved through direct multiple-electrode stimulation with a suprachoroidal retinal prosthesis. Methods: Two of three retinitis pigmentosa patients implanted with a suprachoroidal electrode array were tested on three psychophysical tasks. Electrode patterns were stimulated to elicit perception of simple characters, following which percept localization was tested using either static or dynamic images...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28791596/automated-respiratory-sinus-arrhythmia-measurement-demonstration-using-executive-function-assessment
#9
Meghan Hegarty-Craver, Kristin H Gilchrist, Cathi B Propper, Gregory F Lewis, Samuel J DeFilipp, Jennifer L Coffman, Michael T Willoughby
Respiratory sinus arrhythmia (RSA) is a quantitative metric that reflects autonomic nervous system regulation and provides a physiological marker of attentional engagement that supports cognitive and affective regulatory processes. RSA can be added to executive function (EF) assessments with minimal participant burden because of the commercial availability of lightweight, wearable electrocardiogram (ECG) sensors. However, the inclusion of RSA data in large data collection efforts has been hindered by the time-intensive processing of RSA...
August 8, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28789947/impact-of-5%C3%AE-reductase-inhibitors-on-disease-reclassification-among-men-on-active-surveillance-for-localized-prostate-cancer-with-favorable-features
#10
Charles Dai, Vishnu Ganesan, Joseph Zabell, Yaw A Nyame, Nima Almassi, Daniel J Greene, Daniel Hettel, Chad Reichard, Samuel C Haywood, Hans Arora, Anna Zampini, Alice Crane, Jianbo Li, Ahmed Elshafei, Cristina Magi-Galluzzi, Robert J Stein, Khaled Fareed, Michael Gong, J Stephen Jones, Eric A Klein, Andrew J Stephenson
PURPOSE: To determine the effect of 5α-reductase inhibitors (5-ARI) on disease reclassification in men with prostate cancer optimally selected for active surveillance (AS). MATERIALS AND METHODS: A retrospective review identified 635 patients on AS between 2002-2015. Patients with favorable cancer features on repeat biopsy, defined as absence of Gleason upgrading, were included in the cohort. Patients were stratified by those who did or did not receive finasteride/dutasteride within 1 year of diagnosis...
August 5, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28783153/pecan-library-free-peptide-detection-for-data-independent-acquisition-tandem-mass-spectrometry-data
#11
Ying S Ting, Jarrett D Egertson, James G Bollinger, Brian C Searle, Samuel H Payne, William Stafford Noble, Michael J MacCoss
Data-independent acquisition (DIA) is an emerging mass spectrometry (MS)-based technique for unbiased and reproducible measurement of protein mixtures. DIA tandem mass spectrometry spectra are often highly multiplexed, containing product ions from multiple cofragmenting precursors. Detecting peptides directly from DIA data is therefore challenging; most DIA data analyses require spectral libraries. Here we present PECAN (http://pecan.maccosslab.org), a library-free, peptide-centric tool that robustly and accurately detects peptides directly from DIA data...
August 7, 2017: Nature Methods
https://www.readbyqxmd.com/read/28780594/two-stage-revision-surgery-for-infected-total-knee-replacements-reasonable-function-and-high-success-rate-with-the-use-of-primary-knee-replacement-implants-as-temporary-spacers
#12
Ben Arthur Marson, Samuel T Walters, Benjamin V Bloch, Khosrow Sehat
Two-stage revision surgery for infected total knee replacements remains the gold standard treatment. Articulating spacers are preferred to static spacers for improved functional outcome. Articulating spacers made of cement can be prone to fracture, may not be suitable for full weight bearing, create abrasion debris and necessitate second-stage revision surgery. An alternative is the use of primary knee replacement implants as temporary spacers. With this technique, implants are loosely cemented into place at time of revision, allow the patient reasonable mobility and an ability to fully weight bear and can obviate the need for second-stage surgery...
August 5, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28768841/association-of-parathyroid-hormone-with-20-year-cognitive-decline-the-aric-study
#13
Samuel M Kim, Di Zhao, Andrea L C Schneider, Sai Krishna Korada, Pamela L Lutsey, Eliseo Guallar, Alvaro Alonso, B Gwen Windham, Rebecca F Gottesman, Erin D Michos
OBJECTIVE: We hypothesized that elevated parathyroid hormone (PTH) levels will be independently associated with 20-year cognitive decline in a large population-based cohort. METHODS: We studied 12,964 middle-aged white and black ARIC participants without a history of prior stroke who, in 1990-1992 (baseline), had serum PTH levels measured and cognitive function testing, with repeat cognitive testing performed at up to 2 follow-up visits. Cognitive testing included the Delayed Word Recall, the Digit Symbol Substitution, and the Word Fluency tests, which were summed as a global Z score...
August 2, 2017: Neurology
https://www.readbyqxmd.com/read/28760537/randomized-double-blind-trial-of-amitriptyline-versus-placebo-in-treatment-of-chronic-laryngopharyngeal-neuropathy
#14
Minyoung Jang, Samuel J Rubin, Daniel J Stein, Jacob Pieter Noordzij
OBJECTIVE: A neuropathic etiology has been suggested for patients with chronic laryngopharyngitis symptoms without visible structural pathology. Prior studies have shown that treatment with neuro-modulating medications is beneficial, but it is unknown if this was due to placebo effect. Our objective was to compare the efficacy of amitriptyline versus placebo in treating chronic laryngopharyngeal neuropathy. STUDY DESIGN: Prospective, randomized placebo-controlled trial...
July 12, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28760418/energy-and-nutrient-intake-of-infants-and-young-children-in-pastoralist-communities-of-ethiopia
#15
Girma Mengistu, Tibebu Moges, Aregash Samuel, Kaleab Baye
OBJECTIVE: Nutrient intake from complementary foods often is suboptimal in subsistent farming households of developing countries, but little is known about this in pastoralist communities. The aim of this study was to estimate the energy and nutrient intake of children ages 6 to 23 mo living in pastoralist communities of Ethiopia. METHOD: As part of the Ethiopian National Food Consumption Survey, 24-h dietary recall data were collected through in-home interviews from a nationally representative sample...
September 2017: Nutrition
https://www.readbyqxmd.com/read/28758811/novel-pathologic-scoring-tools-predict-end-stage-kidney-disease-in-light-chain-al-amyloidosis
#16
Samuel Rubinstein, Robert F Cornell, Liping Du, Beatrice Concepcion, Stacey Goodman, Shelton Harrell, Sara Horst, Daniel Lenihan, David Slosky, Agnes Fogo, Anthony Langone
BACKGROUND AND OBJECTIVES: Light chain (AL) amyloidosis frequently involves the kidney, causing significant morbidity and mortality. A pathologic scoring system with prognostic utility has not been developed. We hypothesized that the extent of amyloid deposition and degree of scarring injury on kidney biopsy, could provide prognostic value, and aimed to develop pathologic scoring tools based on these features. METHODS: This is a case-control study of 39 patients treated for AL amyloidosis with biopsy-proven kidney involvement at a large academic medical center...
July 31, 2017: Amyloid: the International Journal of Experimental and Clinical Investigation
https://www.readbyqxmd.com/read/28758522/explanatory-models-and-distress-in-primary-caregivers-of-patients-with-acute-psychotic-presentations-a-study-from-south-india
#17
Deepa S Joy, S D Manoranjitham, P Samuel, K S Jacob
BACKGROUND: Emotional distress among caregivers of people with mental illness is common, changes overtime and requires appropriate coping strategies to prevent long-term disability. Explanatory models, which underpin understanding of disease and illness, are crucial to coping. AIM: To study the association of explanatory models and distress among caregivers of people with acute psychotic illness. METHOD: A total of 60 consecutive patients and their primary caregivers who presented to the Department of Psychiatry, Christian Medical College, Vellore, were recruited for the study...
July 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28753058/attitudes-and-perceptions-from-nursing-and-medical-students-towards-the-other-profession-in-relation-to-wound-care
#18
Anne Friman, Desiree Wiegleb Edström, Samuel Edelbring
Lack of nurse‒physician collaboration in wound care may result in prolonged healing times for patients. In order to facilitate future professional collaboration, undergraduate learning activities in interprofessional education (IPE) have been proposed. The aim of this study was to investigate nursing and medical students' attitudes and perceptions towards each other's future professions and interprofessional collaboration in wound care. Nursing and medical students took part in an interprofessional learning activity about wound care...
July 28, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28750551/midterm-results-of-the-salto-talaris-total-ankle-arthroplasty
#19
Matthew G Stewart, Cindy L Green, Samuel B Adams, James K DeOrio, Mark E Easley, James A Nunley
BACKGROUND: The Salto Talaris total ankle replacement is a modern fixed-bearing implant used to treat symptomatic ankle arthritis with the goals of providing pain relief, restoring mechanical alignment, and allowing motion of the ankle joint. The goal of this study was to report the midterm clinical results of one of the largest cohort of patients in the United States who underwent ankle replacement with this prosthesis. METHODS: This is a review of patients with a minimum of 5 years up to 10 years' follow-up...
July 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28750133/role-of-cytotoxic-tumor-infiltrating-lymphocytes-in-predicting-outcomes-in-metastatic-her2-positive-breast-cancer-a-secondary-analysis-of-a-randomized-clinical-trial
#20
Shuzhen Liu, Bingshu Chen, Samantha Burugu, Samuel Leung, Dongxia Gao, Shakeel Virk, Zuzana Kos, Wendy R Parulekar, Lois Shepherd, Karen A Gelmon, Torsten O Nielsen
Importance: Accumulating evidence indicates that tumor-infiltrating lymphocytes (TILs) are associated with clinical outcomes and may predict the efficacy of chemotherapy and human epidermal growth factor receptor 2 (HER2, encoded by the gene ERBB2)-targeted therapy in patients with HER2-positive breast cancer. Objective: To investigate the role of TILs, particularly cytotoxic CD8+ T cells, in the prediction of outcomes in patients with HER2-positive metastatic breast cancer randomized to an antibody-based (trastuzumab) vs a small molecule-based (lapatinib) anti-HER2 therapy...
July 27, 2017: JAMA Oncology
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