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https://www.readbyqxmd.com/read/29452942/early-safety-and-efficacy-of-the-combination-of-bedaquiline-and-delamanid-for-the-treatment-of-patients-with-drug-resistant-tuberculosis-in-armenia-india-and-south-africa-a-retrospective-cohort-study
#1
Gabriella Ferlazzo, Erika Mohr, Chinmay Laxmeshwar, Catherine Hewison, Jennifer Hughes, Sylvie Jonckheere, Naira Khachatryan, Virginia De Avezedo, Lusine Egazaryan, Amir Shroufi, Stobdan Kalon, Helen Cox, Jennifer Furin, Petros Isaakidis
BACKGROUND: Bedaquiline and delamanid have been approved for treatment of multidrug-resistant (MDR) tuberculosis in the past 5 years. Because of theoretical safety concerns, patients have been unable to access the two drugs in combination. Médecins Sans Frontières has supported the use of combination bedaquiline and delamanid for people with few treatment options since 2016. We describe early safety and efficacy of regimens containing the bedaquiline and delamanid combination in patients with drug-resistant tuberculosis in Yerevan, Armenia; Mumbai, India; and Khayelitsha, South Africa...
February 13, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29425539/-quality-standards-for-ultrasonographic-assessment-of-peripheral-vascular-malformations-and-vascular-tumors-report-of-the-french-society-for-vascular-medicine-2018%C3%A2-update
#2
J P Laroche, S Blaise, F Becker, C Laaeng Massoni, M Nou-Howaldt, O Pichot, H Desmurs-Clavel, J Jeancolas, C Jurus, G Sarlon-Bartoli, V Soulier-Sotto, H Thiel, M A Sevestre-Pietri, J Maloizel-Delaunay, S Mestre-Godin
The quality standards of the French Society of Vascular Medicine for the ultrasonographic assessment of vascular malformations are based on the two following requirements: (1) technical know-how: mastering the use of ultrasound devices and the method of examination; (2) medical know-how: ability to adapt the methods and scope of the examination to its clinical indication and purpose, and to rationally analyze and interpret its results. AIMS OF THE QUALITY STANDARDS: To describe an optimal method of examination in relation to the clinical question and hypothesis...
February 2018: Journal de Médecine Vasculaire
https://www.readbyqxmd.com/read/29403111/implementation-research-reactive-mass-vaccination-with-single-dose-oral-cholera-vaccine-zambia
#3
Marc Poncin, Gideon Zulu, Caroline Voute, Eva Ferreras, Clara Mbwili Muleya, Kennedy Malama, Lorenzo Pezzoli, Jacob Mufunda, Hugues Robert, Florent Uzzeni, Francisco J Luquero, Elizabeth Chizema, Iza Ciglenecki
Objective: To describe the implementation and feasibility of an innovative mass vaccination strategy - based on single-dose oral cholera vaccine - to curb a cholera epidemic in a large urban setting. Method: In April 2016, in the early stages of a cholera outbreak in Lusaka, Zambia, the health ministry collaborated with Médecins Sans Frontières and the World Health Organization in organizing a mass vaccination campaign, based on single-dose oral cholera vaccine...
February 1, 2018: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/29387145/provision-of-emergency-obstetric-care-at-secondary-level-in-a-conflict-setting-in-a-rural-area-of-afghanistan-is-the-hospital-fulfilling-its-role
#4
Daphne Lagrou, Rony Zachariah, Karen Bissell, Catherine Van Overloop, Masood Nasim, Hamsaya Nikyar Wagma, Shafiqa Kakar, Séverine Caluwaerts, Eva De Plecker, Renzo Fricke, Rafael Van den Bergh
Background: Provision of Emergency Obstetric and Neonatal Care (EmONC) reduces maternal mortality and should include three components: Basic Emergency Obstetric and Neonatal Care (BEmONC) offered at primary care level, Comprehensive EmONC (CEmONC) at secondary level and a good referral system in-between. In a conflict-affected province of Afghanistan (Khost), we assessed the performance of an Médecins Sans Frontières (MSF) run CEmONC hospital without a primary care and referral system...
2018: Conflict and Health
https://www.readbyqxmd.com/read/29387144/hiv-associated-kaposi-s-sarcoma-in-maputo-mozambique-outcomes-in-a-specialized-treatment-center-2010-2015
#5
Vini Fardhdiani, Lucas Molfino, Ana Gabriela Zamudio, Rolanda Manuel, Gilda Luciano, Iza Ciglenecki, Barbara Rusch, Laurence Toutous Trellu, Matthew E Coldiron
Background: Kaposi's sarcoma (KS) is a common HIV-associated malignancy associated with disability, pain and poor outcomes. The cornerstone of its treatment is antiretroviral therapy, but advanced disease necessitates the addition of chemotherapy. In high-income settings, this often consists of liposomal anthracyclines, but in Mozambique, the first line includes conventional doxorubicin, bleomycin and vincristine, which is poorly-tolerated. Médecins Sans Frontières supports the Ministry of Health (MOH) in a specialized HIV and KS treatment center at the Centro de Referencia de Alto Maé in Maputo...
2018: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29384084/-m%C3%A3-decine-sciences-2018-a-journal-at-the-very-heart-of-the-debates-and-of-the-current-and-future-research-challenges
#6
EDITORIAL
Jean-Luc Teillaud
No abstract text is available yet for this article.
January 2018: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/29374462/community-participation-during-two-mass-anti-malarial-administrations-in-cambodia-lessons-from-a-joint-workshop
#7
Thomas J Peto, Mark Debackere, William Etienne, Lieven Vernaeve, Rupam Tripura, Gregoire Falq, Chan Davoeung, Chea Nguon, Huy Rekol, Lorenz von Seidlein, Arjen M Dondorp, Nou Sanann, Phaik Yeong Cheah, Martin De Smet, Christopher Pell, Jean-Marie Kindermans
Two mass drug administrations (MDA) against falciparum malaria were conducted in 2015-16, one as operational research in northern Cambodia, and the other as a clinical trial in western Cambodia. During an April 2017 workshop in Phnom Penh the field teams from Médecins Sans Frontières and the Mahidol-Oxford Tropical Medicine Research Unit discussed lessons for future MDAs.
January 27, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29368669/-la-disparition-de-l-expertise-en-m%C3%A3-decine
#8
E J Harvey
No abstract text is available yet for this article.
February 2018: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/29367270/the-bmj-charity-appeal-christmas-2017-help-m%C3%A3-decins-sans-fronti%C3%A3-res-help-child-refugees-worldwide
#9
Richard Hurley
No abstract text is available yet for this article.
January 24, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29364979/navigating-the-risks-of-prevention-of-mother-to-child-transmission-pmtct-of-hiv-services-in-kibera-kenya-barriers-to-engaging-and-remaining-in-care
#10
Kerry A Thomson, Barbara Telfer, Patricia Opondo Awiti, Jane Munge, Mathew Ngunga, Anthony Reid
Within the first year of implementation, 43% of women who tested HIV positive at their first antenatal care visit were no longer retained and being followed in the free prevention of mother to child transmission (PMTCT) of HIV program offered by the Kenyan Ministry of Health and Médecins Sans Frontières in the informal settlement of Kibera, Nairobi. This study aimed to explore barriers to enrolling and remaining engaged in PMTCT services throughout the pregnancy and postpartum periods. Qualitative data from 31 focus group discussions and 35 in-depth interviews across six stakeholder groups that included women, men, and PMTCT service providers were analyzed...
2018: PloS One
https://www.readbyqxmd.com/read/29334324/the-rite-of-passage-of-becoming-a-humanitarian-health-worker-experiences-of-retention-in-sweden
#11
Sara Albuquerque, Anneli Eriksson, Helle M Alvesson
BACKGROUND: Low retention of humanitarian workers poses constraints on humanitarian organisations' capacity to respond effectively to disasters. Research has focused on reasons for humanitarian workers leaving the sector, but little is known about the factors that can elucidate long-term commitment. OBJECTIVE: To understand what motivates and supports experienced humanitarian health workers to remain in the sector. METHODS: Semi-structured interviews were conducted with 10 experienced nurses who had been on at least three field missions with Médecins Sans Frontières Sweden...
2018: Global Health Action
https://www.readbyqxmd.com/read/29298314/improving-mapping-for-ebola-response-through-mobilising-a-local-community-with-self-owned-smartphones-tonkolili-district-sierra-leone-january-2015
#12
Laura M Nic Lochlainn, Ivan Gayton, Georgios Theocharopoulos, Robin Edwards, Kostas Danis, Ronald Kremer, Karline Kleijer, Sumaila M Tejan, Mohamed Sankoh, Augustin Jimissa, Jane Greig, Grazia Caleo
BACKGROUND: During the 2014-16 Ebola virus disease (EVD) outbreak, the Magburaka Ebola Management Centre (EMC) operated by Médecins Sans Frontières (MSF) in Tonkolili District, Sierra Leone, identified that available district maps lacked up-to-date village information to facilitate timely implementation of EVD control strategies. In January 2015, we undertook a survey in chiefdoms within the MSF EMC catchment area to collect mapping and village data. We explore the feasibility and cost to mobilise a local community for this survey, describe validation against existing mapping sources and use of the data to prioritise areas for interventions, and lessons learned...
2018: PloS One
https://www.readbyqxmd.com/read/29297408/nubia-s-mother-being-pregnant-in-the-time-of-experimental-vaccines-and-therapeutics-for-ebola
#13
Séverine Caluwaerts
During the 2014-2016 Ebola epidemic, Médecins Sans Frontières (MSF) treated Ebola-positive pregnant women in its Ebola Treatment Centers (ETCs). For pregnant women with confirmed Ebola virus disease, inclusion in clinical vaccine/drug/therapeutic trials was complicated. Despite their extremely high Ebola-related mortality in previous epidemics (89-93%) and a neonatal mortality of 100%, theoretical concerns about safety of vaccines and therapeutics in pregnancy were invoked, limiting pregnant women's access to an experimental live attenuated vaccine and brincidofovir, an experimental antiviral...
December 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/29288150/the-bmj-charity-appeal-christmas-2017-help-m%C3%A3-decins-sans-fronti%C3%A3-res-volunteer-doctors-help-the-rohingya-people
#14
Jane Feinmann
No abstract text is available yet for this article.
December 29, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29237401/six-monthly-appointment-spacing-for-clinical-visits-as-a-model-for-retention-in-hiv-care-in-conakry-guinea-a-cohort-study
#15
Cavin Epie Bekolo, Abdourahimi Diallo, Mit Philips, Joseph-Desire Yuma, Letizia Di Stefano, Stéphanie Drèze, Jerome Mouton, Youssouf Koita, Ousseni W Tiomtore
BACKGROUND: The outbreak of the Ebola virus disease (EVD) in 2014 led to massive dropouts in HIV care in Guinea. Meanwhile, Médecins Sans Frontières (MSF) was implementing a six-monthly appointment spacing approach adapted locally as Rendez-vous de Six Mois (R6M) with an objective to improve retention in care. We sought to evaluate this innovative model of ART delivery in circumstances where access to healthcare is restricted. METHODS: A retrospective cohort study in 2014 of the outcome of a group of stable patients (viral load ≤1000 copies/μl) enrolled voluntarily in R6M compared with a group of stable patients continuing standard one to three monthly visits in Conakry...
December 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29197357/assessing-the-outcomes-of-hiv-infected-persons-receiving-treatment-for-kaposi-sarcoma-in-conakry-guinea
#16
Cavin E Bekolo, Mohamed M Soumah, Ousseni W Tiemtore, Abdourahimi Diallo, Joseph-Desire Yuma, Letizia Di Stefano, Carol Metcalf, Mohamed Cisse
BACKGROUND: Médecins Sans Frontières is supporting comprehensive HIV care and treatment for Kaposi Sarcoma (KS) in Guinea, where antiretroviral coverage is low and access to KS treatment is very limited. We aimed to evaluate treatment response and survival outcomes of epidemic KS in this setting. METHODS: Retrospective survival analysis of routinely collected clinical data of HIV-infected patients with clinically diagnosed KS, receiving ART and chemotherapy consisting of a combination of bleomycin and vincristine at the Donka National Hospital in Conakry between 2012 and 2015...
December 2, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29191933/the-bmj-charity-appeal-christmas-2017-m%C3%A3-decins-sans-fronti%C3%A3-res-volunteer-doctors-need-your-support
#17
Jane Feinmann
No abstract text is available yet for this article.
November 30, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29176864/health-assessment-of-french-university-students-and-risk-factors-associated-with-mental-health-disorders
#18
Antoine Tran, Laurie Tran, Nicolas Geghre, David Darmon, Marion Rampal, Diane Brandone, Jean-Michel Gozzo, Hervé Haas, Karine Rebouillat-Savy, Hervé Caci, Paul Avillach
OBJECTIVE: The first year of university is a particularly stressful period and can impact academic performance and students' health. The aim of this study was to evaluate the health and lifestyle of undergraduates and assess risk factors associated with psychiatric symptoms. MATERIALS AND METHODS: Between September 2012 and June 2013, we included all undergraduate students who underwent compulsory a medical visit at the university medical service in Nice (France) during which they were screened for potential diseases during a diagnostic interview...
2017: PloS One
https://www.readbyqxmd.com/read/29166354/smoothing-the-transition-points-in-canadian-medical-education
#19
Nick Busing, Jay Rosenfield, Kamal Rungta, Matt Raegele, Andrew Warren, Bruce Wright, Mark Walton, Ivy Oandasan, Anthony Sanfilippo, Anurag Saxena
In 2010 the Association of Faculties of Medicine of Canada, Collège des médecins du Québec, College of Family Physicians of Canada, and the Royal College of Physicians and Surgeons of Canada launched The Future of Medical Education in Canada Postgraduate (FMEC PG) Project to examine postgraduate medical education (PGME) in Canada and make recommendations for improvement. One recommendation that emerged concerns the transitions learners experience across the undergraduate medical education-PGME-practice continuum...
November 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29105556/twenty-five-years-of-french-jurisprudence-in-criminal-medical-liability
#20
Maxime Faisant, Frédérique Papin-Lefebvre, Camille Rerolle, Pauline Saint-Martin, Clotilde Rougé-Maillart
We report on a comprehensive 25-year study on criminal medical liability in France, undertaken to establish trends in the number of cases being brought before the criminal courts. We did this by querying the database on the Légifrance website using a Boolean equation (' pénal' (criminal) AND ' médecin' (physician) OR ' docteur' (doctor)). In total 539 cases were selected, in which the status of the physician either influenced the punishment imposed, or was a prerequisite for the commission of the offence...
January 1, 2017: Medicine, Science, and the Law
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