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https://www.readbyqxmd.com/read/28631089/targeted-temperature-management-in-the-icu-guidelines-from-a-french-expert-panel
#1
REVIEW
Alain Cariou, Jean-François Payen, Karim Asehnoune, Gerard Audibert, Astrid Botte, Olivier Brissaud, Guillaume Debaty, Sandrine Deltour, Nicolas Deye, Nicolas Engrand, Gilles Francony, Stéphane Legriel, Bruno Levy, Philippe Meyer, Jean-Christophe Orban, Sylvain Renolleau, Bernard Vigue, Laure De Saint Blanquat, Cyrille Mathien, Lionel Velly
Over the recent period, the use of induced hypothermia has gained an increasing interest for critically ill patients, in particular in brain-injured patients. The term "targeted temperature management" (TTM) has now emerged as the most appropriate when referring to interventions used to reach and maintain a specific level temperature for each individual. TTM may be used to prevent fever, to maintain normothermia, or to lower core temperature. This treatment is widely used in intensive care units, mostly as a primary neuroprotective method...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28628463/operational-research-during-the-ebola-emergency
#2
Gabriel Fitzpatrick, Tom Decroo, Bertrand Draguez, Rosa Crestani, Axelle Ronsse, Rafael Van den Bergh, Michel Van Herp
Operational research aims to identify interventions, strategies, or tools that can enhance the quality, effectiveness, or coverage of programs where the research is taking place. Médecins Sans Frontières admitted ≈5,200 patients with confirmed Ebola virus disease during the Ebola outbreak in West Africa and from the beginning nested operational research within its emergency response. This research covered critical areas, such as understanding how the virus spreads, clinical trials, community perceptions, challenges within Ebola treatment centers, and negative effects on non-Ebola healthcare...
July 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28604307/laurence-monnais-m%C3%A3-decine-s-et-sant%C3%A3-une-petite-histoire-globale-19e-et-20e-si%C3%A3-cles-montreal-les-presses-de-l-universit%C3%A3-de-montreal-2016-pp-%C3%A2-258-%C3%A2-31-00-paperback-isbn-%C3%A2-978-2-7606-3638-5
#3
https://www.readbyqxmd.com/read/28583317/-the-french-medecine-pricing-committee
#4
D Giorgi
The French medicine pricing committee (CEPS) has to reconcile several major constraints, including optimal patient access to medicines and a good control of expenditures on reimbursable medicines. From 2013 to 2015, drug price decreases and discounts obtained by CEPS contributed more than € 5 billion to the balance of the health insurance accounts. As for price setting, there is a significant drop in the prices of medicines in France once they are registered for reimbursement. France is affected by a limited, but costly, flow of innovative medicines, whose prices are higher than those of previous generations, a reflection of an international gradient to which France is obviously subject, despite prices that remain at the low end of the range in Western Europe...
June 2, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28567113/research-ethics-governance-in-times-of-ebola
#5
Doris Schopper, Raffaella Ravinetto, Lisa Schwartz, Eunice Kamaara, Sunita Sheel, Michael J Segelid, Aasim Ahmad, Angus Dawson, Jerome Singh, Amar Jesani, Ross Upshur
The Médecins Sans Frontières (MSF) ethics review board (ERB) has been solicited in an unprecedented way to provide advice and review research protocols in an 'emergency' mode during the recent Ebola epidemic. Twenty-seven Ebola-related study protocols were reviewed between March 2014 and August 2015, ranging from epidemiological research, to behavioural research, infectivity studies and clinical trials with investigational products at (very) early development stages. This article examines the MSF ERB's experience addressing issues related to both the process of review and substantive ethical issues in this context...
April 2017: Public Health Ethics
https://www.readbyqxmd.com/read/28527614/n-o-344-salpingectomie-opportuniste-et-autres-m%C3%A3-thodes-pour-r%C3%A3-duire-le-risque-de-cancer-de-l-ovaire-de-la-trompe-de-fallope-et-du-p%C3%A3-ritoine-dans-la-population-g%C3%A3-n%C3%A3-rale
#6
Shannon Salvador, Stephanie Scott, Julie Ann Francis, Anita Agrawal, Christopher Giede
OBJECTIF: La présente directive clinique examine les avantages potentiels de la salpingectomie opportuniste pour prévenir le développement du cancer séreux de grade élevé de l'ovaire, de la trompe de Fallope et du péritoine à la lumière de données probantes actuelles selon lesquelles ce type de cancer prendrait naissance dans la trompe de Fallope. UTILISATEURS CIBLES: Gynécologues, obstétriciens, médecins de famille, infirmières autorisées, infirmières praticiennes, résidents et fournisseurs de soins de santé...
June 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28522031/-the-french-medecine-pricing-committee-and-the-medicine-economic-policy-rules-and-competences
#7
D Giorgi
The French medicine pricing committee (CEPS), a governmental and inter-institutional body exercises essential competences for the regulation of the economy of the reimbursable drugs in France. It provides a good example of administered price regulation. It also supervises the proper use of products (control of promotion, conventional control of sales volumes). Finally, it regulates the annual envelope of drug expenditures by means of discounts paid by pharmaceutical companies. The article presents the legal criteria and the doctrine of price setting used in France...
May 15, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28521662/statement-for-doppler-waveforms-analysis
#8
Guillaume Mahé, Carine Boulon, Ileana Desormais, Philippe Lacroix, Luc Bressollette, Jean-Louis Guilmot, Claire Le Hello, Marie-Antoinette Sevestre, Gilles Pernod, Joel Constans, Christian Boissier, Alessandra Bura-Rivière
Peripheral artery disease of the lower limbs (PAD) is a common disease. Evaluation of PAD is primarily based on non-invasive examinations with analysis of the arterial Doppler signal being a key element. However, the description of arterial Doppler waveforms morphologies varies considerably across medical schools and from country to country. In order to overcome this issue, the French College of Teachers for Vascular Medicine (Collège des Enseignants de Médecine Vasculaire; CEMV) has summarised the published data on Doppler waveforms analysis and proposes a new "Saint-Bonnet" classification system to describe Doppler waveforms morphologies...
May 19, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28495205/gatekeeping-and-the-utilization-of-physician-services-in-france-evidence-on-the-m%C3%A3-decin-traitant-reform
#9
Magali Dumontet, Thomas Buchmueller, Paul Dourgnon, Florence Jusot, Jérôme Wittwer
In 2005, France implemented a gatekeeping reform designed to improve care coordination and to reduce utilization of specialists' services. Under this policy, patients designate a médecin traitant, typically a general practitioner, who will be their first point of contact during an episode of care and who will provide referrals to specialists. A key element of the policy is that patients who self-refer to a specialist face higher cost sharing than if they received a referral from their médecin traitant. We consider the effect of this policy on the utilization of physician services...
April 28, 2017: Health Policy
https://www.readbyqxmd.com/read/28489890/unmasking-inequalities-sub-national-maternal-and-child-mortality-data-from-two-urban-slums-in-lagos-nigeria-tells-the-story
#10
Erin Anastasi, Ekanem Ekanem, Olivia Hill, Agnes Adebayo Oluwakemi, Oluwatosin Abayomi, Andrea Bernasconi
INTRODUCTION: Nigeria has one of the highest maternal mortality ratios in the world as well as high perinatal mortality. Unfortunately, the country does not have the resources to assess this critical indicator with the conventional health information system and measuring its progress toward the goal of ending preventable maternal deaths is almost impossible. Médecins Sans Frontières (MSF) conducted a cross-sectional study to assess maternal and perinatal mortality in Makoko Riverine and Badia East, two of the most vulnerable slums of Lagos...
2017: PloS One
https://www.readbyqxmd.com/read/28483482/-sexual-consequences-after-treatment-of-prostate-cancer-inquiry-among-members-of-the-association-nationale-des-malades-du-cancer-de-la-prostate
#11
D Girier, A Chevrot, P Costa, R Thuret, A Faix, A Mestre, S Droupy
INTRODUCTION: Complications of prostate cancer treatments are responsible of a lower quality of life. We evaluated the prevalence and the perceptions of sexual consequences of prostate cancer treatments. MATERIALS AND METHODS: A retrospective self-administered questionnaire was sent to all the members of the Association Nationale des Malades du Cancer de la Prostate (ANAMACAP). All the answers were analyzed. RESULTS: 226 questionnaires were analyzed, the average age was 67...
May 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28459838/ebola-management-centre-proximity-associated-with-reduced-delays-of-healthcare-of-ebola-virus-disease-evd-patients-tonkolili-sierra-leone-2014-15
#12
Georgios Theocharopoulos, Kostas Danis, Jane Greig, Alexandra Hoffmann, Henriette De Valk, Augustine Jimissa, Sumaila Tejan, Mohammed Sankoh, Karline Kleijer, Will Turner, Jay Achar, Jennifer Duncombe, Kamalini Lokuge, Ivan Gayton, Rob Broeder, Ronald Kremer, Grazia Caleo
Between August-December 2014, Ebola Virus Disease (EVD) patients from Tonkolili District were referred for care to two Médecins Sans Frontières (MSF) Ebola Management Centres (EMCs) outside the district (distant EMCs). In December 2014, MSF opened an EMC in Tonkolili District (district EMC). We examined the effect of opening a district-based EMC on time to admission and number of suspect cases dead on arrival (DOA), and identified factors associated with fatality in EVD patients, residents in Tonkolili District...
2017: PloS One
https://www.readbyqxmd.com/read/28458866/a-live-term-intra-abdominal-pregnancy-in-a-field-hospital-a-case-report
#13
Shadi Abdelrahman, Matthew Deeter, Anitha Muthusami, Trine G Peterson, Leen Wackenier
Abdominal pregnancy is a rare form of ectopic pregnancy with high morbidity and mortality for both the mother and the fetus. Diagnosis can be challenging, especially in a resource-limited setting. We report a case of abdominal pregnancy that presented to Médecins Sans Frontières field hospital in Agok, South Sudan, with abdominal pain. Examination revealed a term pregnancy and a live fetus in transverse lie. The diagnosis of abdominal pregnancy was made intraoperatively, with successful management and delivery of a healthy baby...
March 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28456526/strengthening-and-sustainability-of-national-immunization-technical-advisory-groups-nitags-globally-lessons-and-recommendations-from-the-founding-meeting-of-the-global-nitag-network
#14
Alex Adjagba, Noni E MacDonald, Inmaculada Ortega-Pérez, Philippe Duclos
National Immunization Technical Advisory Groups (NITAGs) provide independent, evidence-informed advice to assist their governments in immunization policy formation. However, many NITAGs face challenges in fulfilling their roles. Hence the many requests for formation of a network linking NITAGs together so they can learn from each other. To address this request, the Health Policy and Institutional Development (HPID) Center (a WHO Collaborating Center at the Agence de Médecine Préventive - AMP), in collaboration with WHO, organized a meeting in Veyrier-du-Lac, France, on 11 and 12 May 2016, to establish a Global NITAG Network (GNN)...
April 26, 2017: Vaccine
https://www.readbyqxmd.com/read/28416965/a-crisis-of-protection-and-safe-passage-violence-experienced-by-migrants-refugees-travelling-along-the-western-balkan-corridor-to-northern-europe
#15
Jovana Arsenijević, Erin Schillberg, Aurelie Ponthieu, Lucio Malvisi, Waeil A Elrahman Ahmed, Stefano Argenziano, Federica Zamatto, Simon Burroughs, Natalie Severy, Christophe Hebting, Brice de Vingne, Anthony D Harries, Rony Zachariah
BACKGROUND: Pushed by ongoing conflicts and pulled by the desire for a better life, over one million migrants/refugees transited Balkan countries and arrived in Europe during 2015 and early 2016. To curb this influx, European countries instituted restrictive migration policies often characterized by building of razor-wire border fences and border closures. Among migrants/refugees who received mental health care in Serbia while travelling through Balkan countries to Northern Europe, we assessed the prevalence and patterns of violent events experienced including physical trauma...
2017: Conflict and Health
https://www.readbyqxmd.com/read/28400124/sex-disparities-among-persons-receiving-operative-care-during-armed-conflicts
#16
Joseph D Forrester, Jared A Forrester, Jean-Paul Basimouneye, Mohammad-Zahir Tahir, Miguel Trelles, Adam L Kushner, Sherry M Wren
BACKGROUND: Armed conflict increasingly involves civilian populations, and health care needs may be immense. We hypothesized that sex disparities may exist among persons receiving operative care in conflict zones and sought to describe predictors of disparity. METHODS: We performed a retrospective analysis of operative interventions performed between 2008 and 2014 at Médecins Sans Frontières Operation Center Brussels conflict projects. A Médecins Sans Frontières Operation Center Brussels conflict project was defined as a program established in response to human conflict, war, or social unrest...
April 8, 2017: Surgery
https://www.readbyqxmd.com/read/28364929/professional-changes-induced-by-a-redesigned-immunization-supply-chain-in-the-com%C3%A3-health-zone-benin
#17
Elise Guillermet, Daleb Abdoulaye Alfa, Romule Gbodja, Philippe Jaillard
At the end of 2013, the Government of Benin and Agence de Médecine Préventive (AMP) launched a demonstration project in Comé Health Zone (HZ) to optimize the vaccine supply chain. A key part of the demonstration project was the creation of an "informed push model" of vaccine distribution supported by a new logistician position at the health zone (district) level. At the conclusion of the demonstration project in 2015, the authors conducted an anthropological study consisting of semi-structured interviews with 62 participants to assess how the new model changed the professional identities, roles, responsibilities, and practices of personnel involved in vaccine management during and just after the demonstration project end in Comé HZ...
April 19, 2017: Vaccine
https://www.readbyqxmd.com/read/28328346/efficacy-of-a-low-cost-heat-stable-oral-rotavirus-vaccine-in-niger
#18
RANDOMIZED CONTROLLED TRIAL
Sheila Isanaka, Ousmane Guindo, Celine Langendorf, Amadou Matar Seck, Brian D Plikaytis, Nathan Sayinzoga-Makombe, Monica M McNeal, Nicole Meyer, Eric Adehossi, Ali Djibo, Bruno Jochum, Rebecca F Grais
BACKGROUND: Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate effect in sub-Saharan Africa. METHODS: We conducted a randomized, placebo-controlled trial in Niger to evaluate the efficacy of a live, oral bovine rotavirus pentavalent vaccine (BRV-PV, Serum Institute of India) to prevent severe rotavirus gastroenteritis. Healthy infants received three doses of the vaccine or placebo at 6, 10, and 14 weeks of age...
March 23, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28320759/basic-occupational-health-services-bohs-in-community-primary-care-the-msf-dhaka-model
#19
Venkiteswaran Muralidhar, Md Faizul Ahasan, Ahad Mahmud Khan, Mohammad Shariful Alam
The Médecins Sans Frontiérs (MSF) established basic occupational health services to diagnose and treat work-related diseases among tannery, metal, plastics and garment workers and families in one of the more polluted areas of the world populated by 600 000 people. In spite of project limitations, an analysis of the 6-month data showed that of the original cohort of 5000, 3200 (64%) came for at least 1 consultation. Among them, 468 (14.6%) were diagnosed with suspected work-related diseases as per defined protocols...
March 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28300451/medicine-is-a-science-of-uncertainty-and-an-art-of-probability-la-m%C3%A3-decine-est-une-science-de-l-incertitude-et-un-art-de-la-probabilit%C3%A3
#20
Kirk Barber
No abstract text is available yet for this article.
March 2017: Journal of Cutaneous Medicine and Surgery
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