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https://www.readbyqxmd.com/read/29770210/identification-of-publicly-available-data-sources-to-inform-the-conduct-of-health-technology-assessment-in-india
#1
Laura Downey, Neethi Rao, Lorna Guinness, Miqdad Asaria, Shankar Prinja, Anju Sinha, Rajni Kant, Arvind Pandey, Francoise Cluzeau, Kalipso Chalkidou
Background: Health technology assessment (HTA) provides a globally-accepted and structured approach to synthesising evidence for cost and clinical effectiveness alongside ethical and equity considerations to inform evidence-based priorities. India is one of the most recent countries to formally commit to institutionalising HTA as an integral component of the heath resource allocation decision-making process. The effective conduct of HTA depends on the availability of reliable data.   Methods : We draw from our experience of collecting, synthesizing, and analysing health-related datasets in India and internationally, to highlight the complex requirements for undertaking HTA, and explore the availability of such data in India...
2018: F1000Research
https://www.readbyqxmd.com/read/29760354/development-of-health-technology-assessment-in-china-new-challenges
#2
Yingyao Chen, Yao He, Xunyouzhi Chi, Yan Wei, Lizheng Shi
Health technology assessment (HTA) is a field of scientific policy research that adopts multidisciplinary approaches to conduct systematic evaluation of health technologies and inform decision making. Although achievements have been made by HTA activities among academics, providers, and policy makers, development of the field of HTA in China is fragmented and not yet formally integrated in health policy making processes. All stakeholders need to make more efforts to strengthen HTA knowledge translation and facilitate a decision making process that is based on evidence including HTA findings...
2018: Bioscience Trends
https://www.readbyqxmd.com/read/29754017/reparaci%C3%A3-n-endovascular-para-aneurisma-de-aorta-revisi%C3%A3-n-panor%C3%A3-mica-sobre-su-evidencia-en-el-mundo-y-su-aplicaci%C3%A3-n-en-latinoam%C3%A3-rica
#3
María Calderón, Viviana Brito, Andrea Alcaraz, Lucila Rey-Ares, Federico Augustovski, Sebastián García-Martí, Ariel Bardach, Agustín Ciapponi, Analía López, Andrés Pichón-Riviere
BACKGROUND: Aortic aneurysm (AA) is a pathology with high morbidity and mortality. The management can be expectant, surgical, or through endovascular repair (EVAR). In Latin America the incidence of AA has increased and the analysis of therapeutic options, especially if they are expensive, is fundamental. OBJECTIVE: To analyze available evidence on the effectiveness, safety and coverage policies of the EVAR. METHODOLOGY: Panoramic review in the main bibliographical bases (MEDLINE, LILACS, EMBASE, Cochrane Library, DARE) and generic internet searchers, main health technology assessment (HTA) agencies and health insurance companies...
May 10, 2018: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29753344/challenges-in-research-and-health-technology-assessment-of-rare-disease-technologies-report-of-the-ispor-rare-disease-special-interest-group
#4
Sandra Nestler-Parr, Daria Korchagina, Mondher Toumi, Chris L Pashos, Christopher Blanchette, Elizabeth Molsen, Thomas Morel, Steven Simoens, Zoltán Kaló, Ruediger Gatermann, William Redekop
BACKGROUND: Successful development of new treatments for rare diseases (RDs) and their sustainable patient access require overcoming a series of challenges related to research and health technology assessment (HTA). These impediments, which may be unique to RDs or also apply to common diseases but are particularly pertinent in RDs, are diverse and interrelated. OBJECTIVE: To develop for the first time a catalog of primary impediments to RD research and HTA, and to describe the cause and effect of individual challenges...
May 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29751764/challenges-to-decision-making-processes-in-the-national-hta-agency-in-brazil-operational-procedures-evidence-use-and-recommendations
#5
Tania Yuka Yuba, Hillegonda Maria Dutilh Novaes, Patrícia Coelho de Soárez
BACKGROUND: The quality of the evidence used in health technology assessment (HTA) agency reports has been considered essential for decision-making processes and their legitimacy. In Brazil, CONITEC is the agency responsible for defining data mandatory for the submission of proposals for the incorporation of new technologies. The objective of this study was to analyse CONITEC recommendation reports, the type of scientific evidence used in them and their compliance with operational procedures...
May 11, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29739352/nature-and-reporting-characteristics-of-uk-health-technology-assessment-systematic-reviews
#6
Christopher Carroll, Eva Kaltenthaler
BACKGROUND: A recent study by Page et al. (PLoS Med. 2016;13(5):e1002028) claimed that increasing numbers of reviews are being published and many are poorly-conducted and reported. The aim of the present study was to assess how well reporting standards of systematic reviews produced in a Health Technology Assessment (HTA) context compare with reporting in Cochrane and other 'non-Cochrane' systematic reviews from the same years (2004 and 2014), as reported by Page et al. (PLoS Med. 2016;13(5):e1002028)...
May 8, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29737254/pharmacological-treatment-of-hypertension-effects-in-endothelial-function
#7
Leonardo Cobos-Segarra, Patricio Lopez-Jaramillo, Carlos Ponte-Negretti Ci, Raul Villar, Ernesto Penaherrera
The vascular endothelium plays a crucial role to maintain the functional integrity of the cardiovascular system through the secretion of vasoactive substances such as prostacyclin and NO. Endothelial dysfunction participate in the genesis of HTA, but also hypertension produces endothelial damage. The mayor class of antihypertensive drugs have beneficial effects in the recuperation of the endothelial function, actions that are contributing to explain the impact of the adequate control of HTA in the reduction of CV events...
May 7, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29733227/health-technology-assessment-in-saudi-arabia
#8
Sinaa Al-Aqeel
The Saudi government, similar to any other government, is committed to making public spending more efficient, using resources more effectively, and limiting waste. Health technology assessment (HTA) is a tool that informs policy and decision makers regarding the formulation of safe and effective policies that are patient-focused and help to achieve efficiency when allocating limited healthcare resources. Areas covered: After a brief description of HTA in the international context, this review provides a brief introduction to Saudi Arabia's healthcare system, followed by a delineation of the decision maker(s) and influencers and the decision-making process for pricing and reimbursement...
May 7, 2018: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/29729645/health-technology-assessment-and-its-use-in-drug-policies-in-china
#9
Xuemei Zhen, Xueshan Sun, Hengjin Dong
OBJECTIVE: To review drug policies, health technology assessment (HTA), and HTA's use in drug policies in China, to further improve the quality and efficiency of drugs. METHODS: This study draws on multiple methods. A systematic review of the literature, review of Chinese government documents and statistical handbooks, and authors' experiences in drug policies and HTA in China were combined to achieve the objective. RESULTS: Of 571 studies identified in the initial search, 14 eligible articles (6 English, 8 Chinese) were finally included...
May 2, 2018: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29716606/the-impact-of-orthopaedic-research-evidence-on-health-financing-in-australia
#10
Martin Hua, Daniel Myers, Lachlan Host
BACKGROUND: In Australia, approval by the Medical Services Advisory Committee (MSAC) is an important step in the implementation of new health technologies. The MSAC considers health technology assessments (HTA) when submitting a recommendation to the Minister of Health on a new technology's suitability for public funding. Despite being such a critical tool in formulating policy, there has been little scrutiny on the impact of limited evidence on the performance of a national HTA agency's mandate...
May 2, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29704659/new-drug-reimbursement-and-pricing-policy-in-taiwan
#11
Gau-Tzu Chen, Shu-Chen Chang, Chee-Jen Chang
BACKGROUND: Taiwan has implemented a national health insurance system for more than 20 years now. The benefits of pharmaceutical products and new drug reimbursement scheme are determined by the Expert Advisory Meeting and the Pharmaceutical Benefit and Reimbursement Scheme (PBRS) Joint Committee in Taiwan. OBJECTIVES: To depict the pharmaceutical benefits and reimbursement scheme for new drugs and the role of health technology assessment (HTA) in drug policy in Taiwan...
April 25, 2018: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29703653/testing-a-new-taxonomic-model-for-the-assessment-of-medical-devices-is-it-plausible-and-applicable-insights-from-hta-reports-and-interviews-with-hta-institutions-in-europe
#12
Sabine Fuchs, Britta Olberg, Matthias Perleth, Reinhard Busse, Dimitra Panteli
OBJECTIVE: Medical devices (MDs) encompass a broad and heterogeneous range of technologies. While practices vary considerably across countries, MDs often find application in patient care with little or no evaluation of their effectiveness and safety following market approval. A recently proposed taxonomy of MDs considered devices from the viewpoint of Health Technology Assessment (HTA). The aim of the work presented here was to test its plausibility and applicability by considering real-world HTA practices...
March 14, 2018: Health Policy
https://www.readbyqxmd.com/read/29703227/revealed-preferences-towards-the-appraisal-of-orphan-drugs-in-poland-multi-criteria-decision-analysis
#13
Katarzyna Kolasa, Krzysztof Miroslaw Zwolinski, Vladimir Zah, Zoltán Kaló, Tadeusz Lewandowski
BACKGROUND: A Multi Criteria Decision Analysis (MCDA) technique was adopted to reveal the preferences of the Appraisal Body of the Polish HTA agency towards orphan drugs (OMPs). RESULTS: There were 34 positive and 23 negative HTA recommendations out of 54 distinctive drug-indication pairs. The MCDA matrix consisted of 13 criteria, seven of which made the most impact on the HTA process. Appraisal of clinical evidence, cost of therapy, and safety considerations were the main contributors to the HTA guidance, whilst advancement of technology and manufacturing costs made the least impact...
April 27, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29701348/in-the-current-era-of-endovascular-surgery-what-is-the-role-of-axillofemoral-bypass
#14
Ricardo Correia, Rita Ferreira, Ana Garcia, Frederico Gonçalves, Rodolfo Abreu, Nelson Camacho, Joana Catarino, Maria Emília Ferreira
INTRODUCTION: Nowadays, axillofemoral bypass is viewed as an end-of-line solution for lower limb revascularization, owing to its classically described poor long-term patency, and recent advances in endovascular options for patients with complex aortoiliac anatomy not suitable for open reconstruction. There is a marked difference in patient profiles in published series of axillofemoral bypass, reflecting changing procedures indications due to technical innovations. The objective of this study is to determine the contemporary profile of patients treated with axillofemoral bypass and their outcome...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29695093/furthering-the-evidence-of-the-effectiveness-of-employment-strategies-for-people-with-mental-disorders-in-europe-a-systematic-review
#15
REVIEW
Amalia Muñoz-Murillo, Eva Esteban, Carolina C Ávila, Klemens Fheodoroff, Josep Maria Haro, Matilde Leonardi, Beatriz Olaya
(1) Purpose: This systematic review aims to assess the effectiveness of strategies used in the professional (re)integration of persons with mental disorders (MD) in European countries; (2) Methods: We conducted a search for scientific publications available in relevant electronic databases (Medline, PsycINFO, CDR-HTA, CDR-DARE, and Cochrane Library). The present study collected evidence on the effectiveness, from 2011 to 2016, of employment strategies for persons with MDs; (3) Results: A total of 18 studies were included, representing 5216 participants (aged 18⁻65, mean age of 38...
April 24, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29681868/impaired-cognitive-control-of-emotional-conflict-in-trait-anxiety-a-preliminary-study-based-on-clinical-and-non-clinical-individuals
#16
Yongju Yu, Chenggang Jiang, Haiyan Xu, Qian Yang, Jiawen Li, Yuanyuan Xu, Wenjun Xiang, Li Peng, Botao Liu, Fang Lv, Min Li
Background: It has been observed that trait anxiety easily leads to conflict maladaptation under conflict circumstances. However, it remains unclear whether the precise neural mechanisms underlying the effects of high trait anxiety (HTA) on cognitive control are consistent in high trait anxious individuals, with and without anxiety disorders. Methods: The present study recruited 29 healthy volunteers with low trait anxiety (LTA), 37 healthy volunteers with HTA, and 23 patients with generalized anxiety disorder (GAD)...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29680094/the-use-of-mcda-in-hta-great-potential-but-more-effort-needed
#17
Kevin D Marsh, Mark Sculpher, J Jaime Caro, Tommi Tervonen
The potential for multi-criteria decision analysis (MCDA) to support health technology assessment (HTA) has been much discussed, and various HTA agencies are piloting or applying MCDA. Alongside these developments, good practice guidelines for the application of MCDA in health care have been developed. An assessment of current applications of MCDA to HTA in light of good practice guidelines reveals, however, that many have methodologic flaws that undermine their usefulness. Three challenges are considered: the use of additive models, a lack of connection between criteria scales and weights, and the use of MCDA in economic evaluation...
April 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29674373/study-protocol-quantitative-fibronectin-to-help-decision-making-in-women-with-symptoms-of-preterm-labour-quids-part-2-uk-prospective-cohort-study
#18
Sarah Jane Stock, Lisa M Wotherspoon, Kathleen Anne Boyd, Rachel K Morris, Jon Dorling, Lesley Jackson, Manju Chandiramani, Anna L David, Asma Khalil, Andrew Shennan, Victoria Hodgetts Morton, Tina Lavender, Khalid Khan, Susan Harper-Clarke, Ben Mol, Richard D Riley, John Norrie, Jane Norman
INTRODUCTION: The aim of the QUIDS study is to develop a decision support tool for the management of women with symptoms and signs of preterm labour, based on a validated prognostic model using quantitative fetal fibronectin (fFN) concentration, in combination with clinical risk factors. METHODS AND ANALYSIS: The study will evaluate the Rapid fFN 10Q System (Hologic, Marlborough, Massachusetts, USA) which quantifies fFN in a vaginal swab. In QUIDS part 2, we will perform a prospective cohort study in at least eight UK consultant-led maternity units, in women with symptoms of preterm labour at 22+0  to 34+6 weeks gestation to externally validate a prognostic model developed in QUIDS part 1...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29669674/community-views-on-factors-affecting-medicines-resource-allocation-cross-sectional-survey-of-3080-adults-in-australia
#19
Lesley Chim, Glenn Salkeld, Patrick J Kelly, Wendy Lipworth, Dyfrig A Hughes, Martin R Stockler
Objective The aim of the present study was to determine Australian community views on factors that influence the distribution of health spending in relation to medicines. Methods A cross-sectional web-based survey was performed of 3080 adults aged ≥18 years. Participants were asked to rank, in order of importance, 12 criteria according to which medicines funding decisions may be made. Results Of all respondents, 1213 (39.4%) considered disease severity to be the most important prioritisation criterion for funding a new medicine...
April 19, 2018: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29656722/toward-a-contingency-model-for-hospital-based-health-technology-assessment-evidence-from-adhophta-project
#20
Americo Cicchetti, Valentina Iacopino, Silvia Coretti, Alessandra Fiore, Marco Marchetti, Laura Sampietro-Colom, Kristian Kidholm, Jean-Blaise Wasserfallen, Rabia Kahveci, Esa Halmesmäki, Magdalene Rosenmöller, Claudia Wild, Raul-Allan Kivet
OBJECTIVES: Hospital-based health technology assessment (HB-HTA) is becoming increasingly relevant because of its role in managing the introduction and withdrawal of health technologies. The organizational arrangement in which HB-HTA activities are conducted depends on several contextual factors, although the dominant models have several similarities. The aims of this study were to explore, describe, interpret, and explain seven cases of the application of HB-HTA logic and to propose a classification for HB-HTA organizational models which may be beneficial for policy makers and HTA professionals...
April 16, 2018: International Journal of Technology Assessment in Health Care
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