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HIV mother to child transmission

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https://www.readbyqxmd.com/read/28741134/a-cluster-randomised-trial-to-determine-the-efficacy-of-the-feeding-buddies-programme-in-improving-exclusive-breastfeeding-rates-among-hiv-infected-women-in-rural-kwazulu-natal-south-africa
#1
Penelope Reimers, Kiersten Israel-Ballard, Marlies Craig, Lenore Spies, Ibou Thior, Frank Tanser, Anna Coutsoudis
This cluster randomised trial in KwaZulu-Natal South Africa, evaluated the implementation of a Feeding Buddies (FB) programme to improve exclusive breastfeeding (EBF) amongst human immunodeficiency virus infected mothers. Eight clinics were randomly allocated to intervention and control arms respectively. Pregnant women attending the prevention of mother-to-child transmission program and intending to EBF were enrolled: control (n = 326), intervention (n = 299). Intervention mothers selected FBs to support them and they were trained together (four sessions)...
July 24, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28732085/point-of-care-screening-for-hepatitis-b-virus-infection-in-pregnant-women-at-an-antenatal-clinic-a-south-african-experience
#2
Nafiisah Chotun, Wolfgang Preiser, Christoffel Johannes van Rensburg, Pedro Fernandez, Gerhard Barnard Theron, Dieter Glebe, Monique Ingrid Andersson
BACKGROUND & AIMS: Elimination of HIV and syphilis mother-to-child transmission (MTCT) has received much attention but little consideration has been given to the possibility of elimination of HBV MTCT. In sub-Saharan Africa, HBV vertical transmission continues to be reported and it remains an important public health problem. This study aimed to assess the feasibility of screening pregnant women for HBV using a point-of-care (POC) test and implementing interventions to prevent HBV MTCT...
2017: PloS One
https://www.readbyqxmd.com/read/28722553/travelling-models-and-the-challenge-of-pragmatic-contexts-and-practical-norms-the-case-of-maternal-health
#3
REVIEW
Jean-Pierre Olivier de Sardan, Aïssa Diarra, Mahaman Moha
As in other areas of international development, we are witnessing the proliferation of 'traveling models' developed by international experts and introduced in an almost identical format across numerous countries to improve some aspect of maternal health systems in low- and middle-income countries. These policies and protocols are based on 'miracle mechanisms' that have been taken out of their original context but are believed to be intrinsically effective in light of their operational devices.In reality, standardised interventions are, in Africa and elsewhere, confronted with pragmatic implementation contexts that are always varied and specific, and which lead to drifts, distortions, dismemberments and bypasses...
July 12, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28721963/pediatric-hiv-in-india-current-scenario-and-the-way-forward
#4
REVIEW
Anita Nath
In India, the prevention of parent-to-child transmission and antiretroviral therapy services for HIV-infected mothers and children have been rapidly scaled up over the recent years. Despite these advances, a large number of HIV-infected children are born in every year. A thorough literature review has been done by retrieving related studies (published from the year 2000 onward); using a Medline search and by extracting recent findings from the official websites of the National AIDS Control Organization, UNAIDS, UNICEF, and World Health Organization...
April 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28718496/-introduction-of-rapid-syphilis-and-hiv-testing-in-prenatal-care-in-colombia-qualitative-analysis
#5
María Teresa Ochoa-Manjarrés, Hernando Guillermo Gaitán-Duarte, Sidia Caicedo, Berta Gómez, Freddy Pérez
Objective: Interpret perceptions of Colombian health professionals concerning factors that obstruct and facilitate the introduction of rapid syphilis and HIV testing in prenatal care services. Methods: A qualitative study based on semi-structured interviews was carried out. A convenience sample was selected with 37 participants, who included health professionals involved in prenatal care services, programs for pregnant women, clinical laboratories, and directors of health care units or centers, as well as representatives from regional departments and the Ministry of Health...
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28717383/what-influences-feeding-decisions-for-hiv-exposed-infants-in-rural-kenya
#6
Helen M Nabwera, Joyline Jepkosgei, Kelly W Muraya, Amin S Hassan, Catherine S Molyneux, Rehema Ali, Andrew M Prentice, James A Berkley, Martha K Mwangome
BACKGROUND: Infant feeding in the context of human immunodeficiency virus (HIV) poses unique challenges to mothers and healthcare workers in balancing the perceived risks of HIV transmission and nutritional requirements. We aimed to describe the decision-making processes around infant feeding at a rural HIV clinic in Kenya. METHODS: We used a qualitative study design. Between March and August 2011, we conducted in-depth interviews (n = 9) and focus group discussions (n = 10) with purposively selected hospital and community respondents at Kilifi County Hospital, Kenya...
2017: International Breastfeeding Journal
https://www.readbyqxmd.com/read/28714809/reticence-in-disclosure-of-hiv-infection-and-reasons-for-bereavement-impact-on-perinatally-infected-adolescents-mental-health-and-understanding-of-hiv-treatment-and-prevention-in-johannesburg-south-africa
#7
Nataly Woollett, Vivian Black, Lucie Cluver, Heena Brahmbhatt
Survival rates of perinatally infected HIV-positive adolescents (PIA) are increasing in sub-Saharan Africa. There is a gap in understanding how disclosure and bereavement have an impact on PIA beliefs and understanding of their HIV infection and its management. In-depth interviews were conducted with 25 purposively selected adolescents aged 13-19 years from 5 public health clinics in Johannesburg, South Africa. Data were analysed using NVivo 10 using a thematic approach. PIA experience incomplete disclosure both of their HIV status and reasons for their bereavements, which limits their understanding of how they became infected, vertical transmission and prevention options like prevention of mother-to-child transmission (PMTCT)...
July 17, 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/28707345/the-cascade-of-care-to-prevent-mother-to-child-transmission-in-rio-de-janeiro-brazil-1996-2013-improving-but-still-some-way-to-go
#8
Cristina Barroso Hofer, Matthias Egger, Mary-Ann Davies, Ana Cristina Cisne Frota, Ricardo Hugo de Oliveira, Thalita Fernandes Abreu, Lúcia Evangelista Araújo, Bernardo Bastos Witthlin, Alice Weber Carvalho, Janaína Rivas Cordeiro, Giulia Pasqualini Lima, Olivia Keiser
OBJECTIVE: To describe the cascade of care to HIV mother-to-child-transmission (PMTCT) in a Rio de Janeiro reference pediatric clinic, and evaluate the main factors possibly associated with HIV transmission. METHODS: Data on antenatal care, perinatal and neonatal assistance to HIV-infected and HIV-exposed but uninfected children assisted in the clinic from 1996-2013 were collected. The cascade of care was graphically demonstrated, and possible factors associated with HIV infection were described using regression models for bivariate and multivariate analysis...
July 14, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28706083/wealth-related-inequality-in-early-uptake-of-hiv-testing-among-pregnant-women-an-analysis-of-data-from-a-national-cross-sectional-survey-south-africa
#9
Nobubelo Kwanele Ngandu, Carine Van Malderen, Ameena Goga, Niko Speybroeck
OBJECTIVES: Wealth-related inequality across the South African antenatal HIV care cascade has not been considered in detail as a potential hindrance to eliminating mother-to-child HIV transmission (EMTCT). We aimed to measure wealth-related inequality in early (before enrolling into antenatal care) uptake of HIV testing and identify the contributing determinants. DESIGN: Cross-sectional survey. SETTINGS: South African primary public health facilities in 2012...
July 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28705148/correlates-of-facility-delivery-for-rural-hiv-positive-pregnant-women-enrolled-in-the-moment-nigeria-prospective-cohort-study
#10
Nadia A Sam-Agudu, Christopher Isah, Chinenye Fan-Osuala, Salome Erekaha, Habib O Ramadhani, Udochisom Anaba, Olusegun A Adeyemi, Grace Manji-Obadiah, Daniel Lee, Llewellyn J Cornelius, Manhattan Charurat
BACKGROUND: Low rates of maternal healthcare service utilization, including facility delivery, may impede progress in the prevention of mother-to-child transmission of HIV (PMTCT) and in reducing maternal and infant mortality. The MoMent (Mother Mentor) study investigated the impact of structured peer support on early infant diagnosis presentation and postpartum maternal retention in PMTCT care in rural Nigeria. This paper describes baseline characteristics and correlates of facility delivery among MoMent study participants...
July 14, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28704472/prevention-of-mother-to-child-transmission-of-hiv-option-b-cascade-in-rural-tanzania-the-one-stop-clinic-model
#11
Anna Gamell, Lameck Bonaventure Luwanda, Aneth Vedastus Kalinjuma, Leila Samson, Alex John Ntamatungiro, Maja Weisser, Winfrid Gingo, Marcel Tanner, Christoph Hatz, Emilio Letang, Manuel Battegay
BACKGROUND: Strategies to improve the uptake of Prevention of Mother-To-Child Transmission of HIV (PMTCT) are needed. We integrated HIV and maternal, newborn and child health services in a One Stop Clinic to improve the PMTCT cascade in a rural Tanzanian setting. METHODS: The One Stop Clinic of Ifakara offers integral care to HIV-infected pregnant women and their families at one single place and time. All pregnant women and HIV-exposed infants attended during the first year of Option B+ implementation (04/2014-03/2015) were included...
2017: PloS One
https://www.readbyqxmd.com/read/28695551/cohort-profile-the-kilombero-and-ulanga-antiretroviral-cohort-kiularco-a-prospective-hiv-cohort-in-rural-tanzania
#12
Emilio Letang, Aneth Vedastus Kalinjuma, Tracy R Glass, Anna Gamell, Herry Mapesi, George Rocky Sikalengo, Lameck Bonaventure Luwanda, Dorcas Mnzava, Alex J Ntamatungiro, Regina Ndaki, Gideon Francis, Fiona Vanobberghen, Hansjakob Furrer, Thomas Klimkait, Ingrid Felger, Marcel Tanner, Christoph Hatz, Maja Weisser, Manuel Battegay, Kiularco Study Group
BACKGROUND: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) is a single-site, open and ongoing prospective cohort of people living with human immunodeficiency virus (PLWHIV) established in 2005 at the Chronic Diseases Clinic of Ifakara (CDCI), within the Saint Francis Referral Hospital (SFRH) in Ifakara, Tanzania. The objectives of KIULARCO are to (i) provide patient and cohort-level information on the outcomes of HIV treatment; (ii) provide cohort-level information on opportunistic infections and comorbidities; (iii) evaluate aspects of human immunodeficiency virus (HIV) care and treatment that have national or international policy relevance; (iv) provide a platform for studies on improving HIV care and treatment in sub-Saharan Africa; and (v) contribute to generating local capacity to deal with the challenges posed by the HIV/AIDS pandemic in this region...
July 11, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28683718/rate-of-hiv-transmission-and-associated-factors-among-hiv-exposed-infants-in-selected-health-facilities-of-east-and-west-gojjam-zones-northwest-ethiopia-retrospective-cohort-study
#13
Nurilign Abebe Moges, Getachew Mullu Kassa, Dube Jara Boneya
BACKGROUND: In 2014, there were 170,000 new HIV-infected children globally. The rate of HIV transmission from mother to child in Ethiopia was 18%. Though there are a number of HIV-related studies conducted in Ethiopia, there is a scarcity of evidence on the rate of mother to child transmission. So, the aim of this study was to determine the rate of HIV transmission and associated factors among HIV-exposed infants in selected health facilities in East and West Gojjam Zones, Northwest Ethiopia...
July 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28679418/transitioning-from-antenatal-surveillance-surveys-to-routine-hiv-testing-a-turning-point-in-the-mother-to-child-transmission-prevention-programme-for-hiv-surveillance-in-brazil
#14
Gerson Fernando Mendes Pereira, Meritxell Sabidó, Alessandro Caruso, Adele Schwartz Benzaken
BACKGROUND: In Brazil, due to the rapid increase in programmes for the prevention of mother-to-child transmission (PMTCT), routine programme data are widely available. The objective of this study was to assess the utility of programmatic data to replace HIV surveillance based on the antenatal care (ANC) surveillance survey (SS). METHODS: We analysed ANC SS data from 219 maternity service clinics. PMTCT variables were extracted from the ANC SS data collection form, which allowed us to capture and compare the ANC SS data and PMTCT HIV test results for each pregnant woman who completed the ANC SS...
July 5, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28670636/attitudes-of-female-street-vendors-towards-hiv-aids-in-vhembe-district-of-south-africa
#15
Olaniyi Fc, Tshitangano Tg, Tugli Ak, Amosu Am, Edokpayi Jn
BACKGROUND: The Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) are still global health problems. This study was conducted to describe the attitudes of female street vendors (FSV) in Thohoyandou, Vhembe district, towards HIV/AIDS and those infected with the virus. MATERIALS AND METHODS: A quantitative, cross-sectional survey design was adopted. Data were collected by means of a structured, self-administered questionnaire and analyzed using the Statistical Package for Social Sciences (SPSS) version 20...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28668338/-analysis-of-prenatal-abuse-in-catalonia-between-the-years-2011-and-2014
#16
Jordi Garcia Garcia, Elena Campistol Mas, María Ángeles López-Vilchez, María José Morcillo Buscato, Antonio Mur Sierra
INTRODUCTION: Foetal abuse is that intentional or negligent act that causes a harmful effect to the foetus. It is a type of abuse difficult to diagnose and handle. Some indicators of suspicion are the absence of gestational control, the maternal consumption of toxic substances, or the problematic maternal social environment. OBJECTIVE: To analyse the cases of foetal abuse registered in Catalonia between 2011 and 2014 to identify the risk profile. METHODS: A cross-sectional descriptive study was conducted on a sample of 222 cases of prenatal abuse registered in Catalonia between 2011 and 2014...
June 28, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28663779/antiretroviral-therapy-containing-raltegravir-to-prevent-mother-to-child-transmission-of-hiv-in-infected-pregnant-women
#17
Diego M Cecchini, Marina G Martinez, Laura M Morganti, Claudia G Rodriguez
We conducted a retrospective study in a general hospital in Buenos Aires, Argentina (2009-2015) aimed at evaluating outcomes in HIV-infected pregnant women (HIPW), who were prescribed raltegravir (RAL)-containing antiretroviral therapy (ART). A total of 239 HIPW were enrolled in our study; among them 31 received RAL (12.9%) at different clinical stages: i) intensification (INS): addition of RAL to current ART because of detectable antepartum viral load, 13 (41.9%); ii) late presenter (LP): standard ART + RAL as fourth drug, 15 (48...
May 31, 2017: Infectious Disease Reports
https://www.readbyqxmd.com/read/28662036/prevention-of-mother-to-child-transmission-of-hiv-postpartum-adherence-to-option-b-until-18-months-in-western-uganda
#18
Sarah Decker, Eva Rempis, Alexandra Schnack, Vera Braun, John Rubaihayo, Priscilla Busingye, Nazarius Mbona Tumwesigye, Gundel Harms, Stefanie Theuring
Since 2012, the WHO recommends Option B+ for the prevention of mother-to-child transmission of HIV. This approach entails the initiation of lifelong antiretroviral therapy in all HIV-positive pregnant women, also implying protection during breastfeeding for 12 months or longer. Research on long-term adherence to Option B+ throughout breastfeeding is scarce to date. Therefore, we conducted a prospective observational cohort study in Fort Portal, Western Uganda, to assess adherence to Option B+ until 18 months postpartum...
2017: PloS One
https://www.readbyqxmd.com/read/28655683/integration-of-prevention-of-mother-to-child-hiv-transmission-into-maternal-health-services-in-senegal
#19
C Cisse
The objective of this study was to assess the level of integration of prevention of mother-to-child HIV transmission (PMTCT) in facilities providing services for maternal, newborn, and child health (MNCH) and reproductive health (RH) in Senegal. The survey, conducted from August through November, 2014, comprised five parts : a literature review to assess the place of this integration in the health policies, standards, and protocols in effect in Senegal; an analysis by direct observation of attitudes and practices of 25 healthcare providers at 5 randomly-selected obstetrics and gynecology departments representative of different levels of the health pyramid; a questionnaire evaluating knowledge and attitudes of 10 providers about the integration of PMTCT services into MNCH/RH facilities; interviews to collect the opinions of 70 clients, including 16 HIV-positive, about the quality of PMTCT services they received; and a questionnaire evaluating knowledge and opinions of 14 policy-makers/managers of health programs focusing on mothers and children about this integration...
June 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28654643/elimination-of-mother-to-child-transmission-of-hiv-and-syphilis-emtct-process-progress-and-program-integration
#20
Melanie Taylor, Lori Newman, Naoko Ishikawa, Maura Laverty, Chika Hayashi, Massimo Ghidinelli, Razia Pendse, Lali Khotenashvili, Shaffiq Essajee
Melanie Taylor and colleagues discuss progress towards eliminating vertical transmission of HIV and syphilis.
June 2017: PLoS Medicine
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