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https://www.readbyqxmd.com/read/28945061/a-comparative-study-of-cfd-of-canine-model-of-common-carotid-fusiform-aneurysm-and-vertebrobasilar-fusiform-aneurysm-in-human-patients
#1
Shewei Guo, Peng Jiang, Jian Liu, Xinjian Yang, Chuhan Jiang, Youxiang Li, Zhongxue Wu
BACKGROUND: Intracranial fusiform aneurysm (IFA) is a relatively uncommon subgroup of aneurysms. There are few reports that focus on the hemodynamics of IFA. In this study, we compared the hemodynamics of the canine model of common carotid fusiform aneurysm and vertebrobasilar fusiform aneurysms in human patients. METHODS: Five male mongrel dogs were randomly chosen, and there unilateral common carotid artery (CCA) and external jugular vein were surgically exposed individually...
September 22, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28944992/ginsenoside-rb1-enhances-atherosclerotic-plaque-stability-by-skewing-macrophages-to-the-m2-phenotype
#2
Xue Zhang, Ming-Hao Liu, Lei Qiao, Xin-Yu Zhang, Xiao-Ling Liu, Mei Dong, Hong-Yan Dai, Mei Ni, Xiao-Rong Luan, Jun Guan, Hui-Xia Lu
Atherosclerosis (AS) is characterized as progressive arterial plaque, which is easy to rupture under low stability. Macrophage polarization and inflammation response plays an important role in regulating plaque stability. Ginsenoside Rb1 (Rb1), one of the main active principles of Panax Ginseng, has been found powerful potential in alleviating inflammatory response. However, whether Rb1 could exert protective effects on AS plaque stability remains unclear. This study investigated the role of Rb1 on macrophage polarization and atherosclerotic plaque stability using primary peritoneal macrophages isolated from C57BL/6 mice and AS model in ApoE(-/-) mice...
September 25, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28944945/safety-and-efficacy-of-ventriculostomy-procedures-under-dual-antiplatelet-therapy-in-patients-treated-with-stent-assisted-coiling-in-subarachnoid-hemorrhage
#3
Soner Civi, Cagatay Andic, Ozgur Kardes, Halil İbrahim Suner, Emre Durdag, Ozlem Ozmete, Kadir Tufan
AIM: Stent assisted coilling (SAC) is an alternative in the treatment of ruptured aneurysms. Stenting requires the use of dual antiplatelet agents. Hydrocephaly is a complication of subarachnoid hemorrhage (SAH) requiring ventriculostomy. Antiplatelet treatment reveal a risk of hemorrhage in ventriculostomy. Anti-aggregant effect starts at least four hours after the initial doses of treatment. However, in many studies, ventriculostomy was performed before antiplatelet treatment and the hemorrhagic complications were related to the procedure...
July 16, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28944940/ruptured-distal-accessory-anterior-cerebral-artery-aneurysm-a-case-report-and-literature-review
#4
Alperen Sirin, Ulas Cikla, Kutluay Uluc, Mustafa Kemal Baskaya
Aneurysms of the distal anterior cerebral artery (dACA) are rare, consisting only 2-6% of all intracranial aneurysms. dACA aneurysms are often associated with anomalies such as azygous, bihemispheric and triplication of ACA. Among these anomalies accessory anterior cerebral artery (accACA) is an anatomical variant found in 3.3% to 15% of the population. Here we report a case of a 60-year-old female who presented with a Hunt and Hess grade II, Fisher grade III subarachnoid hemorrhage secondary to a ruptured saccular aneurysm originating from the pericallosal-callosomarginal artery bifurcation at the A3 segment of the accessory ACA and underwent an uncomplicated microsurgical clipping...
July 12, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28944933/emergency-department-management-of-body-packers-and-body-stuffers
#5
Liv Heymann-Maier, Lionel Trueb, Sabine Schmidt, Pierre-Nicolas Carron, Olivier Hugli, Eric Heymann, Bertrand Yersin
Trafficking and sale of narcotics frequently involves the intra-abdominal transport of large quantities of drugs, usually cocaine or heroin ("body packing"), or, when there is a risk of being arrested, the oral ingestion of minor quantities of narcotics dedicated for immediate resale ("body stuffing"). This study aimed to describe the characteristics, complications and medical follow through of 132 cases of body packing (n = 36), cases of body stuffing (n = 83) or mixed cases (n = 13), referred by the authorities to our emergency department over the course of 12 years...
September 25, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28944130/brain-computed-tomography-angiography-as-an-ancillary-test-in-the-confirmation-of-brain-death
#6
Homa Sadeghian, Mohammad Ali Raeisi, Parviz Dolati, Rouzbeh Motiei-Langroudi
Introduction Brain death (BD) is the irreversible termination of the functioning of the brain. The diagnosis should be first made by clinical criteria and confirmed by using paraclinical confirmatory techniques (ancillary tests). While conventional brain angiography remains the standard method of choice, computed tomography angiography (CTA) has emerged as an alternative method. In this study, we tried to evaluate the accuracy of CTA for the diagnosis of BD. Methods In this study, we included nine patients with a clinical diagnosis of BD, confirmed by electroencephalography (EEG)...
July 19, 2017: Curēus
https://www.readbyqxmd.com/read/28943906/hepatectomy-for-spontaneous-rupture-of-hepatocellular-carcinoma-without-portal-triad-clamping
#7
Zhi-Ming Wang, Xin-Sheng Lu, Fu Qiu
Hepatectomy without portal triad clamping may decrease the incidence of liver injury; however, the effects of hepatectomy without portal triad clamping in the treatment of spontaneous rupture of hepatocellular carcinoma (SRHCC) remain unclear. The aims of the present study were to evaluate the therapeutic value of hepatectomy without portal triad clamping in the treatment of patients with SRHCC. The present study retrospectively reviewed patients with SRHCC who received hepatectomy without portal triad clamping (non-clamping group) and the therapeutic efficacy was compared with that of 20 patients with SRHCC undergoing the same surgery in the presence of portal triad clamping (clamping group)...
October 2017: Oncology Letters
https://www.readbyqxmd.com/read/28943436/vitamin-d-receptor-protects-glioblastoma-a172%C3%A2-cells-against-coxsackievirus-a16-infection-induced-cell-death-in-the-pathogenesis-of-hand-foot-and-mouth-disease
#8
Meiling Qu, Shunxiang Di, Shuyun Zhang, Zhiqun Xia, Guohong Quan
Hand, foot, and mouth disease (HFMD) was one of the most common children illnesses. Coxsackievirus A16 was one of the major pathogens that cause HFMD. However, the role of vitamin D underlying this common illness has not been elucidated. Our study examined that vitamin D levels was significantly lower in 33 HFMD patients, compared to 36 healthy children. Unexpectedly, both mRNA and protein expression of VDR were significantly decreased in CA16 infected glioblastoma A172 cells. And overexpression of VDR or vitamin D treatment in CA16 infected glioblastoma A172 cells could reverse the CA16 infection induced cell death, apoptosis or mitochondrial membrane rupture...
September 21, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28943415/management-of-blood-blister-like-aneurysms-of-the-internal-carotid-artery-lessons-learned-from-direct-clipping-in-22-cases
#9
Zheng Liu, Shangming Zhang, Shousen Wang, Qizuan Chen
OBJECTIVE: To present a case series of blood blister-like aneurysms (BBAs) of the internal carotid artery (ICA) and an assessment of diagnosis and treatment options, attempting to identify surgical or endovascular management of BBAs with a low complication rate and a functional outcome. METHODS: A retrospective analysis including diagnosis and treatment options of BBAs of the ICA was performed of patients treated for BBAs at Fuzhou General Hospital from January 2008 to September 2016...
September 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28943089/ehd-proteins-cooperate-to-generate-caveolar-clusters-and-to-maintain-caveolae-during-repeated-mechanical-stress
#10
Ivana Yeow, Gillian Howard, Jessica Chadwick, Carolina Mendoza-Topaz, Carsten G Hansen, Benjamin J Nichols, Elena Shvets
Caveolae introduce flask-shaped convolutions into the plasma membrane and help to protect the plasma membrane from damage under stretch forces. The protein components that form the bulb of caveolae are increasingly well characterized, but less is known about the contribution of proteins that localize to the constricted neck. Here we make extensive use of multiple CRISPR/Cas9-generated gene knockout and knockin cell lines to investigate the role of Eps15 Homology Domain (EHD) proteins at the neck of caveolae...
September 14, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28943056/imaging-modalities-in-the-diagnosis-and-monitoring-of-achilles-tendon-ruptures-a-systematic-review
#11
REVIEW
Olivier C Dams, Inge H F Reininga, Jan L Gielen, Inge van den Akker-Scheek, Johannes Zwerver
OBJECTIVE: To determine the role of imaging in the diagnosis and monitoring of the Achilles tendon rupture (ATR). STUDY DESIGN: Systematic review. DATA SOURCES: PubMed and EMBASE in November 2016. ELIGIBILITY CRITERIA: Clinical studies providing information on the methods and role of imaging in the diagnosis and monitoring of the ATR were included. RESULTS: Fifty-six studies were included, most concerning the use of ultrasound (n=37) or MRI (n=18)...
September 18, 2017: Injury
https://www.readbyqxmd.com/read/28942415/confusion-and-abdominal-symptoms-following-a-rugby-tackle
#12
Demetris Ioannides, Madeleine Davies, Stefan Kluzek
A 19-year-old man was sent to the emergency department following a pitch-side assessment for suspected concussion, unexplained upper abdominal tenderness and vomiting, following a high-impact tackle during a rugby match. A Focussed Assessment with Sonography for Trauma (FAST) scan performed in the emergency department suggested intra-abdominal free fluid, and subsequent head and abdominal CT imaging showed no intracranial lesion but confirmed a significant haemoperitoneum due to large splenic tear and bleeding...
September 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28942401/fulminant-myocardial-bleeding-another-clinical-course-of-vascular-ehlers-danlos-syndrome
#13
Masahide Tokue, Hidehiko Hara, Kenji Kurosawa, Masato Nakamura
Vascular Ehlers-Danlos Syndrome (vEDS) is a dominantly inherited connective tissue disorder characterised by colon rupture and arterial aneurysm, dissection and rupture. A patient was diagnosed with vEDS after a spontaneous colon rupture when he was brought to our institute because of sudden chest pain. An ECG revealed wide regional ST elevation, which was initially suggestive of acute myocarditis. On the second day, haemodynamics suddenly deteriorated because of a rapid accumulation of bloody pericardial effusion, and the patient died...
September 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28942396/microbubble-enhanced-ultrasound-to-demonstrate-urethral-transection-in-a-case-of-penile-fracture
#14
Oliver Czarnecki, Conrad Brice von Stempel, Pippa Sangster, Miles Walkden
A 47-year-old man attended the emergency department following trauma during sexual intercourse after which he developed penile swelling and haematuria several hours later. A penile fracture was suspected but given the slightly atypical history, ultrasound was performed to look for a fracture. Given the history of haematuria, both a standard Doppler ultrasound and a microbubble-enhanced retrograde ultrasound urethrogram were performed. The Doppler confirmed the suspected diagnosis of penile fracture, and microbubble urethrogram demonstrated a urethral injury...
September 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28942079/death-by-heroin-intoxication-in-a-body-pusher-with-an-innovative-packaging-technique-case-report-and-review-of-the-literature
#15
Sindi Visentin, Greta Bevilacqua, Chiara Giraudo, Caterina Dengo, Alessandro Nalesso, Massimo Montisci
Death due to mechanical or chemical intoxication of heroin body packers, thanks to the continuous improvement in packaging techniques, are increasingly rare, and almost all the cases reported in the literature refer to drug swallowers. A case of fatal acute heroin intoxication in a body pusher with an unreported packaging technique is presented, and previous deaths due to heroin body packing are reviewed, taking into consideration imaging techniques performed, cause of death, toxicological analysis on biological and non-biological samples, as well as number, position and type of drug packages identified at the dissection of the body...
September 8, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28941683/analysis-of-dehydration-kinetics-status-of-water-and-oil-distribution-of-microwave-assisted-vacuum-frying-potato-chips-combined-with-nmr-and-confocal-laser-scanning-microscopy
#16
Ya Su, Min Zhang, Zhongxiang Fang, Weiming Zhang
In this study, the dehydration kinetics, status of water and oil distribution of microwave-assisted vacuum frying (MVF) potato chips were analyzed combining with NMR and confocal laser scanning microscopy (CLSM). Results showed that the MVF markedly increased the moisture evaporation kinetics and effective moisture diffusivity compared to vacuum frying (VF). The higher microwave power level (1000W) used achieved higher moisture evaporation rate and higher effective moisture diffusivity, The Logarithmic model exhibited the best fit for the obtained data of MR versus frying time in the MVF...
November 2017: Food Research International
https://www.readbyqxmd.com/read/28940730/fifty-one-cases-of-fungal%C3%A2-arteritis-after-kidney-transplantation-a-case-report-and-review-of-the-literature
#17
Maozhi Tang, Xiaosong Xu, Bingbing Shen, Jun Zhang, Peng Li, Qianguang Pan, Mei Mei, Pan Xie, Hong Liu
Fungal arteritis affecting graft arteries is a rare but life-threatening complication in kidney transplantation (KT). Here, we report the case of a patient with Aspergillus arteritis who experienced renal artery rupture 8 days after KT. We also reviewed 50 other reported cases of fungal arteritis after KT. We found that fungal contamination can occur during kidney graft harvest, preservation, and/or transplantation. Typically, early diagnosis, timely antifungal treatment, and emergency surgery seem crucial for avoiding life-threatening vascular complications...
September 20, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28939676/the-protective-effect-of-middle-cerebral-artery-calcification-on-symptomatic-middle-cerebral-artery-infarction
#18
Jang-Hyun Baek, Joonsang Yoo, Dongbeom Song, Young Dae Kim, Hyo Suk Nam, Ji Hoe Heo
BACKGROUND AND PURPOSE: The presence of intracranial artery calcification is associated with an increased risk for stroke. However, calcified atherosclerotic plaques are also known to be less vulnerable to rupture. Given this discrepancy, we investigated whether the vulnerability of intracranial arterial atherosclerosis differed based on the presence or absence of calcification. METHODS: We considered consecutive patients with acute stroke in the unilateral middle cerebral artery (MCA) territory...
September 22, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28939539/falxuplication-a-novel-method-for-wrap-clipping-a-fusiform-aneurysm-a-technical-note
#19
Martin M Mortazavi, Tania Hassanzadeh, Kianoush Khalili, Sajid S Suriya, M Asif Taqi, Salman A Fard, R Shane Tubbs
BACKGROUND: Various techniques have been used for wrap-clipping a ruptured, fusiform intracranial aneurysm. However, there is no available literature on use of the falx cerebri for wrap-clipping. OBJECTIVE: We present a review of the literature with an illustrative case, with a ruptured fusiform pericallosal artery aneurysm firmly attached to the lower edge of the falx cerebri and not amenable to endovascular intervention. METHODS: While the firm attachment between the inferior falx and the fusiform aneurysm was maintained, a section of the lower thinner part of the falx cerebri firmly attached to the aneurysm was dissected and wrapped around the fusiform aneurysm, stabilized with a fenestrated clip...
September 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28939208/discovery-and-characterization-of-human-amniochorionic-membrane-microfractures
#20
Lauren S Richardson, Gracie Vargas, Tyra Brown, Lorenzo Ochoa, Samantha Sheller-Miller, George R Saade, Robert N Taylor, Ramkumar Menon
This study obtained visual evidence of novel cellular and extracellular matrix level structural alterations in term and preterm human fetal amniochorionic membrane. Amniochorions were collected from term cesarean (not in labor) or vaginal deliveries (labor), preterm premature rupture of the membranes, and spontaneous preterm birth. To determine the effect of oxidative stress on membranes at term or preterm labor, term not in labor samples in an organ explant culture in vitro were exposed to cigarette smoke extract...
September 19, 2017: American Journal of Pathology
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