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https://www.readbyqxmd.com/read/29929147/transformation-products-of-amoxicillin-and-ampicillin-after-photolysis-in-aqueous-matrices-identification-and-kinetics
#1
Juliana Bazzan Arsand, Rodrigo Barcellos Hoff, Louise Jank, Lucas N Meirelles, M Silvia Díaz-Cruz, Tânia Mara Pizzolato, Damià Barceló
Antibiotics are widely used in human medicine and veterinary production. Residues of these compounds reach the water sources through waste or direct application (e.g. aquaculture). The constant input of the parent drugs and their transformation products into the environment leads these pharmaceuticals to be considered as emerging pollutants. For some molecules, the pathway of degradation and formation in products is less known. To assess the impact of these substances in the environment and in the human health, it is necessary to elucidate the transformation products and their kinetic of degradation to evaluate the possible risks...
June 18, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29920285/electrochemical-remediation-of-amoxicillin-detoxification-and-reduction-of-antimicrobial-activity
#2
Lara Barroso Brito, Luane Ferreira Garcia, Marcos Pereira Caetano, Germán Sanz Lobón, Mayk Teles de Oliveira, Rhaul de Oliveira, Ieda Maria Sapateiro Torres, Alfonso Yepez, Boniek Gontijo Vaz, Rafael Luque, Cesar Koppe Grisolia, Marize Campos Valadares, Eric de Souza Gil, Gisele Augusto Rodrigues de Oliveira
Amoxicillin (AMX) is one of the most commonly prescribed antibiotics around the world to treat and prevent several diseases in both human and veterinary medicine. Incomplete removal of AMX during wastewater treatment contributes to its presence in water bodies and drinking water. AMX is an emerging contaminant since its impact on the environment and human health remains uncertain. This contribution was aimed to evaluate the electrochemical oxidation (EO) of AMX using different anodes in tap water, NaCl or Na2 SO4 solutions and to evaluate the potential toxicity of remaining AMX and its by-products on zebrafish early-life stages...
June 16, 2018: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29900784/review-psychopathologies-in-captive-nonhuman-primates-and-approaches-to-diagnosis-and-treatment
#3
Maya S Kummrow, Martin Brüne
  Despite the growing knowledge and literature on primate medicine, assessment and treatment of behavioral abnormalities in nonhuman primates (NHPs) is an underdeveloped field. There is ample evidence for similarity between humans and great apes, including basic neurologic physiology and emotional processes, and no substantial argument exists against a concept of continuity for abnormal conditions in NHPs that emerge in response to adverse experiences, akin to human psychopathology. NHPs have served as models for human psychopathologies for many decades, but the acquired knowledge has only hesitantly been applied to primates themselves...
June 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29890331/recombinant-production-of-a-chimeric-antimicrobial-peptide-in-e-coli-and-assessment-of-its-activity-against-some-avian-clinically-isolated-pathogens
#4
Abass Tanhaiean, Marjan Azghandi, Jamshid Razmyar, Elyass Mohammadi, Mohammad Hadi Sekhavati
Over the last decades, poultry industry faced to the rapid emergence of multidrug-resistant bacteria as a global concern. Antimicrobial peptide (AMPs) known as potential antibiotic alternative and were considered as a new antimicrobial agent. Current methods of production and purification of AMPs have several limitations such as: costly, time-consuming and killing the producing host cells in recombinant form. In the present study, a chimeric peptide derived from camel lactoferrin was produced in Escherichia coli periplasmic space using a pET-based expression system and its antibacterial activity was determined on some avian pathogens in vitro...
June 8, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29889458/is-stroke-indeed-a-monday-morning-disease
#5
András Folyovich, Anna Béres-Molnár K, Judit Gimesi-Országh, Lajos Katona, Dávid Biczó, Károly Vörös, Gábor Gőbl, András Ajtay, Dániel Bereczki
Background and purpose: The therapeutic time window of acute stroke is short. Decision on the use of intravenous thrombolysis is based on well-defined criteria. Any delay in the transport to a designated stroke centre decreases the odds of therapeutic success. In Hungary, the admission rate of stroke patients peaks on Monday, the number gradually decreasing by the end of the week. This phenomenon has long been suggested to be due to the lack of emergency care approach. According to the literature, however, returning to work following a holiday is a risk factor for acute stroke...
May 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29767451/feline-ureteral-obstructions-part-1-medical-management
#6
REVIEW
D L Clarke
Feline ureteral obstructions are an increasingly recognised and challenging diagnostic and management problem. Many cats with ureteral obstructions are critically ill at the time of diagnosis, especially if there is dysfunction of the contralateral kidney. They may present with varying severities of acute kidney injury, electrolyte disturbances, and may have comorbidities such as heart disease that complicate perioperative and long-term management. Medical management, which may consist of rehydration and restoration of intravascular volume with intravenous fluid therapy, osmotic diuresis, ureteral muscle relaxation, and antimicrobials for infection, is important in feline ureteral obstruction patients...
May 16, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29763680/risk-assessment-of-fluoroquinolones-from-poultry-muscle-consumption-comparing-healthy-adult-and-pre-school-populations
#7
André M P T Pereira, Liliana J G Silva, Jéssica Rodrigues, Celeste Lino, Angelina Pena
Antibiotics, especially fluoroquinolones (FQs), have been largely used in animal husbandry namely poultry production. Therefore, this study aimed to identify, quantify and estimate the daily intake for adult and 3-year-old populations of the FQs norfloxacin (NOR), ciprofloxacin (CIP) and enrofloxacin (ENR) through poultry muscle consumption. The results showed detection frequencies of 78% and 62% in supermarket and school canteen samples, respectively. Of the 182 analysed samples, 4 did not comply with ENR maximum residue level (MRL), and 9 were contaminated with NOR, not allowed as a veterinary medicine of food-producing animals...
May 12, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29666821/probiotics-for-the-control-of-helminth-zoonosis
#8
REVIEW
Abadi Amare Reda
This paper is a comprehensive, concise, and an up to date review about probiotics effect and mechanisms against helminth infections of zoonotic importance. Zoonoses are diseases that can be transmitted from animals to humans in a reversible way. Despite zoonotic helminth diseases being still a challenge to the public health and the agriculture industries globally, they were still neglected in both human and veterinary medicine. Moreover, the increasing emergence of anthelmintic drug resistance constitutes failures of most disease control strategies, alarming for a quest to new alternative control approaches...
2018: Journal of Veterinary Medicine
https://www.readbyqxmd.com/read/29623873/antimicrobial-resistance-in-campylobacter-spp
#9
Zhangqi Shen, Yang Wang, Qijing Zhang, Jianzhong Shen
Campylobacter is a major foodborne pathogen and has become increasingly resistant to clinically important antimicrobials. To cope with the selection pressure from antimicrobial use in both veterinary and human medicine, Campylobacter has developed multiple mechanisms for antibiotic resistance, including modification or mutation of antimicrobial targets, modification or inactivation of antibiotics, and reduced drug accumulation by drug efflux pumps. Some of these mechanisms confer resistance to a specific class of antimicrobials, while others give rise to multidrug resistance...
April 2018: Microbiology Spectrum
https://www.readbyqxmd.com/read/29619015/colonization-dynamics-of-cefotaxime-resistant-bacteria-in-beef-cattle-raised-without-cephalosporin-antibiotics
#10
Raies A Mir, Thomas A Weppelmann, Lin Teng, Alexander Kirpich, Mauricio A Elzo, Joseph D Driver, Kwangcheol C Jeong
The emergence of infections caused by antimicrobial resistant microorganisms (ARMs) is currently one of the most important challenges to public health and medicine. Though speculated to originate at least partially from the overuse of antibiotics during food animal production, we hypothesized that cattle are exposed to ARMs in the environment. In this cohort study, a herd of beef calves with no previous exposure to antibiotics was followed during the first year of life in order to investigate the rate of colonization by bacteria resistant to the third-generation cephalosporin cefotaxime...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29615264/extended-spectrum-beta-lactamase-esbl-and-carbapenemase-producing-enterobacteriaceae-in-water-sources-in-lebanon
#11
Mohamad Diab, Monzer Hamze, Richard Bonnet, Estelle Saras, Jean-Yves Madec, Marisa Haenni
Extended-spectrum beta-lactamases (ESBLs) have been recurrently reported in both human and veterinary medicine, and carbapenemases have also emerged in these two sectors. Such resistance phenotypes were increasingly reported in the environment, which both receives and further disseminates multidrug-resistant (MDR) bacteria. Here, we report the high contamination of water samples (68.2%; 15/22) collected in estuaries in Lebanon. From these 15 contaminated sites, a total of 21 ESBL-producing (mostly harbouring the blaCTX-M-15 gene) and four carbapenemase-producing (two blaOXA-48 and two blaOXA-244 ) Enterobacteriaceae were recovered...
April 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29603417/antimicrobial-activity-of-preparations-after-combined-cultivation-of-lactic-acid-bacteria-and-yeast-strains
#12
Ts R Balabekyan, K J Karapetyan, T V Khachatryan, G E Khachatryan, S Sh Tatikyan
Use of antimicrobials in both human and animal populations over the past several decades has led to the emergence of multidrug-resistant bacteria populations that are resistant to many commercially available drugs. For example, acquired resistance to first-line antimicrobial agents increasingly complicates the management of extra-intestinal infections due to Escherichia coli, which are a major source of illness and death. The continued development of new classes of natural antimicrobial agents, possessing antibacterial activity, has become of increasing importance for medicine and veterinary...
March 30, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29602241/incidence-of-and-associated-factors-for-bacterial-colonization-of-intravenous-catheters-removed-from-dogs-in-response-to-clinical-complications
#13
Pedro Jose Guzmán Ramos, Cristina Fernández Pérez, Tania Ayllón Santiago, M Rosario Baquero Artigao, Gustavo Ortiz-Díez
BACKGROUND: Infection rate associated with intravenous (IV) catheter placement is emerging as an important issue in small animal veterinary medicine, mostly because of the economic costs associated with these infections. Identification of possible associated factors may provide useful information for the surveillance and prevention of such infections. OBJECTIVES: To determine the incidence of positive bacterial cultures obtained from IV catheters used in dogs hospitalized for at least 48 hours and removed because of clinical complication...
May 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29535301/rapid-rise-of-the-esbl-and-mcr-1-genes-in-escherichia-coli-of-chicken-origin-in-china-2008-2014
#14
Congming Wu, Yingchao Wang, Xiaomin Shi, Shuang Wang, Hongwei Ren, Zhangqi Shen, Yang Wang, Juchun Lin, Shaolin Wang
Extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC) strains are emerging around the world as a source of resistance to β-lactam antibiotics such as ampicillin, cefotaxime, and ceftazidime. mcr-1 is a novel plasmid-mediated gene conferring resistance to colistin. The aim of this study was to investigate the prevalence of ESBL-EC mcr-1 of chicken origin in the different provinces of China during 2008-2014. Overall, 341 of 821 isolates were determined to be ESBL-EC strains, and the proportion of ESBL-positive strains almost doubled from 2008 to 2014...
March 14, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29534809/practical-fluid-therapy-and-treatment-modalities-for-field-conditions-for-horses-and-foals-with-gastrointestinal-problems
#15
REVIEW
C Langdon Fielding
With advances in technology and owner education, field management in equine veterinary medicine continues to evolve. Equine gastrointestinal disease is one of the most common types of emergencies evaluated by equine practitioners, and many of these patients can be effectively managed in the field. Although the equine veterinarian must make numerous decisions, fluid therapy, pain management, and antimicrobial use are 3 of the major choices that must be addressed when initiating field treatment of equine gastrointestinal disease...
April 2018: Veterinary Clinics of North America. Equine Practice
https://www.readbyqxmd.com/read/29528809/histologic-characterization-of-eosinophilic-encephalitis-in-horses-in-florida
#16
Whitney M Zoll, Dhani Prakoso, Michael Dark, Junjie Liu, Heather Stockdale-Walden, Maureen T Long
Eosinophils within the central nervous system are abnormal and are usually associated with fungal or parasitic infections in horses. Causative agents include Halicephalobus gingivalis, Sarcocystis neurona, and Neospora hughesi. Confirmation of these organisms via specific testing is typically not performed, and final diagnoses are often presumptive. With molecular technology, many of these organisms can now be confirmed. This is important for emerging and zoonotic pathogens, including Angiostrongylus cantonensis, an emerging parasite of interest in the southeastern United States...
May 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29484301/the-one-health-concept-10-years-old-and-a-long-road-ahead
#17
REVIEW
Delphine Destoumieux-Garzón, Patrick Mavingui, Gilles Boetsch, Jérôme Boissier, Frédéric Darriet, Priscilla Duboz, Clémentine Fritsch, Patrick Giraudoux, Frédérique Le Roux, Serge Morand, Christine Paillard, Dominique Pontier, Cédric Sueur, Yann Voituron
Over the past decade, a significant increase in the circulation of infectious agents was observed. With the spread and emergence of epizootics, zoonoses, and epidemics, the risks of pandemics became more and more critical. Human and animal health has also been threatened by antimicrobial resistance, environmental pollution, and the development of multifactorial and chronic diseases. This highlighted the increasing globalization of health risks and the importance of the human-animal-ecosystem interface in the evolution and emergence of pathogens...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29389253/bovine-milk-comparative-proteome-analysis-from-early-mid-and-late-lactation-in-the-cattle-breed-malnad-gidda-bos-indicus
#18
Praseeda Mol, Uday Kannegundla, Gourav Dey, Lathika Gopalakrishnan, Manjunath Dammalli, Manish Kumar, Arun H Patil, Marappa Basavaraju, Akhila Rao, Kerekoppa P Ramesha, Thottethodi Subrahmanya Keshava Prasad
Bovine milk is important for both veterinary medicine and human nutrition. Understanding the bovine milk proteome at different stages of lactation has therefore broad significance for integrative biology and clinical medicine as well. Indeed, different lactation stages have marked influence on the milk yield, milk constituents, and nourishment of the neonates. We performed a comparative proteome analysis of the bovine milk obtained at different stages of lactation from the Indian indigenous cattle Malnad Gidda (Bos indicus), a widely available breed...
March 2018: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/29363210/in-vitro-antimicrobial-activity-of-narasin-against-common-clinical-isolates-associated-with-canine-otitis-externa
#19
Wei Yee Chan, Elizabeth E Hickey, Manouchehr Khazandi, Stephen W Page, Darren J Trott, Peter B Hill
BACKGROUND: Antimicrobial resistance and antimicrobial stewardship are of ever-increasing importance in veterinary medicine. Re-purposing of old drugs that are not used in human medicine is one approach that addresses the emergence of multidrug resistance in canine skin and ear infections, and can reduce the use of critically important human antibiotic classes. HYPOTHESIS/OBJECTIVES: To determine the antimicrobial activity of narasin, a polyether ionophore conventionally used as a rumen modifier and anticoccidial agent in production animals, against common clinical isolates of canine otitis externa (OE)...
April 2018: Veterinary Dermatology
https://www.readbyqxmd.com/read/29276617/antimicrobial-resistance-in-human-populations-challenges-and-opportunities
#20
REVIEW
S Allcock, E H Young, M Holmes, D Gurdasani, G Dougan, M S Sandhu, L Solomon, M E Török
Antimicrobial resistance (AMR) is a global public health threat. Emergence of AMR occurs naturally, but can also be selected for by antimicrobial exposure in clinical and veterinary medicine. Despite growing worldwide attention to AMR, there are substantial limitations in our understanding of the burden, distribution and determinants of AMR at the population level. We highlight the importance of population-based approaches to assess the association between antimicrobial use and AMR in humans and animals. Such approaches are needed to improve our understanding of the development and spread of AMR in order to inform strategies for the prevention, detection and management of AMR, and to support the sustainable use of antimicrobials in healthcare...
2017: Global health, epidemiology and genomics
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