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https://www.readbyqxmd.com/read/28626858/antibiotics-for-acute-bronchitis
#1
REVIEW
Susan M Smith, Tom Fahey, John Smucny, Lorne A Becker
BACKGROUND: The benefits and risks of antibiotics for acute bronchitis remain unclear despite it being one of the most common illnesses seen in primary care. OBJECTIVES: To assess the effects of antibiotics in improving outcomes and to assess adverse effects of antibiotic therapy for people with a clinical diagnosis of acute bronchitis. SEARCH METHODS: We searched CENTRAL 2016, Issue 11 (accessed 13 January 2017), MEDLINE (1966 to January week 1, 2017), Embase (1974 to 13 January 2017), and LILACS (1982 to 13 January 2017)...
June 19, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28614835/aging-of-competitive-athletes
#2
Hirofumi Tanaka
Demographics of human aging are rapidly changing. As illustrated in the biomedicalization of aging, an ever increasing number of older adults is affected by a variety of clinical conditions and diseases, including vascular stiffening, sarcopenia, physical disability, and poor quality of life. One population that is situated in the opposite end of the health and functional spectrum to the sedentary frail elderly is Masters athletes. These older competitive athletes are endowed with substantial functional capacity, overall long-term health, high motivation, and psychosocial outlook...
June 15, 2017: Gerontology
https://www.readbyqxmd.com/read/28599819/between-the-best-way-to-deliver-patient-care-and-chaos-and-low-clinical-value-general-practitioners-and-practice-managers-views-on-data-sharing
#3
Mila Petrova, Matthew Barclay, Sam S Barclay, Stephen I G Barclay
OBJECTIVE: In the UK, General Practitioners and Practice Managers are key to enabling health information exchange (typically referred to as 'data sharing'). This study aimed to survey GPs and PMs for familiarity, engagement with and perceptions of patient data sharing. METHODS: Cross-sectional survey. All 107 general practices in England's second largest Clinical Commissioning Group, Cambridgeshire & Peterborough CCG. Descriptive statistics; hierarchical logistic regression; thematic analysis...
August 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28596252/success-in-bone-marrow-failure-novel-therapeutic-directions-based-on-the-immune-environment-of-myelodysplastic-syndromes
#4
REVIEW
Alyssa H Cull, Michael J Rauh
Myelodysplastic syndromes (MDS) are clonal neoplasms of aging that are associated with BM failure, related cytopenias, fatigue, susceptibility to infections, bruising, bleeding, a shortened lifespan, and a propensity for leukemic transformation. Most frail, elderly patients are not candidates for curative allogeneic BM transplantations and instead receive expectant management, supportive blood transfusions, or empirical, nontargeted therapy. It has been known for some time that MDS arises in an abnormal BM immune environment; however, connections have only recently been established with recurring MDS-associated mutations...
June 8, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28596151/survey-on-advance-care-planning-of-italian-outpatients-on-chronic-haemodialysis
#5
Nicola Panocchia, Giuseppe Tonnara, Roberta Minacori, Dario Sacchini, Maurizio Bossola, Luigi Tazza, Giovanni Gambaro, Antonio Gioacchino Spagnolo
OBJECTIVES: The clinical practice guidelines published by the Renal Physicians Association (USA) recommend instituting advance care planning (ACP) for patients with end-stage renal disease. Studies on this issue are lacking in Italy. Our aim was to determine the attitudes of patients on ACP in our dialysis centre. METHODS: We performed a cross-sectional survey. We recruited patients on maintenance haemodialysis (HD) at Hemodialysis Center of Università Cattolica del Sacro Cuore, from 1 March 2014 to 31 March 2015...
June 8, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28583470/insights-into-the-current-management-of-older-adults-with-type-2-diabetes-in-the-ontario-primary-care-setting
#6
Graydon S Meneilly, Lori D Berard, Alice Y Y Cheng, Peter J Lin, Lori MacCallum, Ross T Tsuyuki, Jean-François Yale, Nahal Nasseri, Jean-François Richard, Lianne Goldin, Anatoly Langer, Mary K Tan, Lawrence A Leiter
OBJECTIVE: The Goal Oriented controL of Diabetes in the Elderly populatioN (GOLDEN) Program assessed the management of older persons with type 2 diabetes in Canadian primary care. METHODS: Data were extracted from the records of 833 consecutively identified persons 65 years of age or older who had type 2 diabetes and were taking 1 antihyperglycemic agent or more; they were managed by 64 physicians from 36 Ontario clinics. RESULTS: More than half (53%) had glycated hemoglobin (A1C) levels of 7...
June 2, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28579766/effects-of-multi-domain-interventions-in-pre-frail-elderly-on-frailty-functional-and-cognitive-status-a-systematic-review
#7
REVIEW
Lenore Dedeyne, Mieke Deschodt, Sabine Verschueren, Jos Tournoy, Evelien Gielen
BACKGROUND: Frailty is an aging syndrome caused by exceeding a threshold of decline across multiple organ systems leading to a decreased resistance to stressors. Treatment for frailty focuses on multi-domain interventions to target multiple affected functions in order to decrease the adverse outcomes of frailty. No systematic reviews on the effectiveness of multi-domain interventions exist in a well-defined frail population. OBJECTIVES: This systematic review aimed to determine the effect of multi-domain compared to mono-domain interventions on frailty status and score, cognition, muscle mass, strength and power, functional and social outcomes in (pre)frail elderly (≥65 years)...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28566447/management-of-endocrine-disease-l-thyroxine-replacement-therapy-in-the-frail-elderly-a-challenge-in-clinical-practice
#8
Rosaria Maddalena Ruggeri, Francesco Trimarchi, Bernadette Biondi
The number of elderly people, mostly over 85 years (the "oldest old"), is increasing worldwide. As a consequence, accompanying morbidity and disability have been increasing, and frailty, defined as an age-related condition of decline of physiological reserves and vulnerability, represents an emerging problem. Caring for older frail people may represent a challenge, since the elderly differ significantly from younger adults in terms of comorbidity, polypharmacy, pharmacokinetics and greater vulnerability to adverse drug reactions...
May 31, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28552878/medium-chain-triglycerides-in-combination-with-leucine-and-vitamin-d-benefit-cognition-in-frail-elderly-adults-a-randomized-controlled-trial
#9
Sakiko Abe, Osamu Ezaki, Motohisa Suzuki
The combined supplementation of medium-chain triglycerides (MCTs), L-leucine-rich amino acids, and cholecalciferol (vitamin D3) increase muscle strength and function in frail elderly individuals. However, their effects on cognition are unknown. We enrolled 38 elderly nursing home residents (mean age±SD, 86.6±4.8 y) in a 3-mo randomized, controlled, parallel group trial. The participants were randomly allocated to 3 groups: the first group received a L-leucine (1.2 g)- and cholecalciferol (20 μg)-enriched supplement with 6 g of MCT (LD+MCT); the second group received the same supplement with 6 g of long-chain triglycerides (LD+LCT); and the third group did not receive any supplements (control)...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28537324/validation-of-the-photography-method-for-nutritional-intake-assessment-in-hospitalized-elderly-subjects
#10
F Monacelli, M Sartini, V Bassoli, D Becchetti, A L Biagini, A Nencioni, M Cea, R Borghi, F Torre, P Odetti
OBJECTIVE: The aim of the present study was to validate the photographic indirect method as an accurate and specific tool to assess nutritional intake in a cohort of elderly hospitalized patients. DESIGN: this is a prospective observational study. SETTING: hospital (geriatric acute ward and transitional care of IRCCSS AUO San Martino Hospital, Genoa, Italy). PARTICIPANTS: 255 consecutive elderly hospitalized patients...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28526382/quality-of-diet-and-level-of-physical-performance-related-to-inflammatory-markers-in-community-dwelling-frail-elderly-people
#11
Do-Yeon Kim, Chang-O Kim, Hyunjung Lim
OBJECTIVE: The aim of this study was to assess whether diet quality and functional status were associated with serum levels of interleukin (IL)-6 and tumor necrosis factor (TNF)-α in frail, elderly, community-dwelling individuals. METHODS: Seventy-eight frail, elderly individuals (age ≥65 y, usual gait speed <0.6 m/s and Mini Nutritional Assessment <24) participated in this cross-sectional study from the National Home Healthcare Services in Gangbuk-gu, Seoul, South Korea...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28487242/oxidative-stress-genomic-features-and-dna-repair-in-frail-elderly-a-systematic-review
#12
REVIEW
María Sánchez-Flores, Diego Marcos-Pérez, Solange Costa, João Paulo Teixeira, Stefano Bonassi, Eduardo Pásaro, Blanca Laffon, Vanessa Valdiglesias
Frailty is an emerging geriatric syndrome characterized by higher vulnerability to stressors, with an increased risk of adverse health outcomes such as mortality, morbidity, disability, hospitalization, and institutionalization. Although it is generally recognized to have a biological basis, no particular biological trait has been consistently associated to frailty status so far. In this work, epidemiological studies evaluating association of frailty status with alterations at cellular level - namely oxidative stress, genomic instability and DNA damage and repair biomarkers -were revised and compared...
May 6, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28476126/key-aspects-related-to-implementation-of-risk-stratification-in-health-care-systems-the-assehs-study
#13
Joana Mora, Miren David Iturralde, Lucía Prieto, Cristina Domingo, Marie-Pierre Gagnon, Catalina Martínez-Carazo, Anna Giné March, Daniele De Massari, Tino Martí, Marco Nalin, Francesca Avolio, Jean Bousquet, Esteban de Manuel Keenoy
BACKGROUND: The lack of proven efficacy of new healthcare interventions represents a problem for health systems globally. It is partly related to suboptimal implementation processes, leading to poor adoption of new interventions. Activation of Stratification Strategies and Results of the interventions on frail patients of Healthcare Services (ASSEHS) EU project (N° 2013 12 04) aims to study current existing health Risk Stratification (RS) strategies and tools on frail elderly patients...
May 5, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28475664/dynamical-resilience-indicators-in-time-series-of-self-rated-health-correspond-to-frailty-levels-in-older-adults
#14
Sanne M W Gijzel, Ingrid A van de Leemput, Marten Scheffer, Mattia Roppolo, Marcel G M Olde Rikkert, René J F Melis
Background: We currently still lack valid methods to dynamically measure resilience for stressors before the appearance of adverse health outcomes that hamper well-being. Quantifying an older adult's resilience in an early stage would aid complex decision-making in health care. Translating complex dynamical systems theory to humans, we hypothesized that three dynamical indicators of resilience (variance, temporal autocorrelation, and cross-correlation) in time series of self-rated physical, mental, and social health were associated with frailty levels in older adults...
July 1, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28473281/linear-and-nonlinear-analysis-of-postural-control-in-frailty-syndrome
#15
Verena de Vassimon-Barroso, Aparecida Maria Catai, Marcele Stephanie De Souza Buto, Alberto Porta, Anielle Cristhine De Medeiros Takahashi
BACKGROUND: Adaptive postural control can be impaired in the presence of frailty syndrome, given that this condition causes homeostatic dysregulation in physiological systems. OBJECTIVES: To compare the center of pressure (CoP) displacements of non-frail, pre-frail, and frail elderly subjects in the standing position before and after postural transition of sitting and rising from a chair, using linear and nonlinear methods. METHODS: Forty-two elderly subjects were divided into 3 groups: non-frail (n=15), pre-frail (n=15), and frail (n=12)...
April 9, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28459359/care-tasks-in-the-stress-process-for-family-caregivers-in-urban-china
#16
Jinyu Liu, Nan Lu, Vivian W Q Lou
OBJECTIVES: To explore the role of care tasks in the caregiving stress process, this study tested the relationships between distinct care tasks, primary stressors, caregiver burden, and depressive symptoms among caregivers. METHODS: The data were collected from a sample of 754 caregivers who provided care for frail, elderly family members in Shanghai, China. Path analysis was conducted to identify the relationships between the three types of care tasks (monetary support, physical care and emotional care), the caregivers' background, primary stressors, caregiver burden, and depressive symptoms...
March 10, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/28446440/nod-for-atezolizumab-in-advanced-bladder-cancer
#17
(no author information available yet)
The FDA approved atezolizumab to treat advanced bladder cancer when cisplatin chemotherapy is contraindicated. The approval offers a potentially more effective alternative to carboplatin-based chemotherapy for frail, elderly patients.
June 2017: Cancer Discovery
https://www.readbyqxmd.com/read/28420687/home-visits-to-frail-elderly-can-save-money-and-angst
#18
Brit Cooper-Jones, Katelyn Verstraten
No abstract text is available yet for this article.
April 18, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28419042/geriatric-fracture-care-future-trajectories-a-2015-aoa-critical-issues-symposium
#19
Julie A Switzer, Kevin J Bozic, Stephen L Kates
The population of the United States and the world is aging rapidly. Musculoskeletal care for older adults will be impacted by the manner in which health care is financed and the ability of the orthopaedic community to provide evidence-based integrated care for this population. We review the financial aspects of health-care reform and the implications for musculoskeletal care in the elderly. We discuss the establishment of quality measures for hip fracture care in the elderly, team building to accomplish this, and an innovative program designed to provide orthopaedic care to the frail elderly outside of the usual office setting...
April 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28413364/delivering-integrated-care-to-the-frail-elderly-the-impact-on-professionals-objective-burden-and-job-satisfaction
#20
Benjamin Janse, Robbert Huijsman, Ruben Dennis Maurice de Kuyper, Isabelle Natalina Fabbricotti
BACKGROUND: The impact of integrated working on professionals' objective burden and job satisfaction was examined. An evidence-based intervention targeting frail elderly patients was implemented in the Walcheren region of the Netherlands in 2010. The intervention involved the primary care practice as a single entry point, and included proactive frailty screening, a comprehensive assessment of patient needs, case management, multidisciplinary teams, care plans and protocols, task delegation and task specialisation, a shared information system, a geriatric care network and integrated funding...
August 17, 2016: International Journal of Integrated Care
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