keyword
MENU ▼
Read by QxMD icon Read
search

fennel

keyword
https://www.readbyqxmd.com/read/28428087/searching-for-new-sources-of-innovative-products-for-the-food-industry-within-halophyte-aromatic-plants-in-vitro-antioxidant-activity-and-phenolic-and-mineral-contents-of-infusions-and-decoctions-of-crithmum-maritimum-l
#1
Catarina Guerreiro Pereira, Luísa Barreira, Nuno da Rosa Neng, José Manuel Florêncio Nogueira, Cátia Marques, Tamára F Santos, João Varela, Luísa Custódio
Aromatic halophyte plants are an outstanding source of bioactive compounds and natural products with potential use in the food industry. This work reports the in vitro antioxidant activity, toxicity, polyphenolic profile and mineral contents of infusions and decoctions from stems, leaves and flowers of Crithmum maritimum L., an aromatic and edible maritime halophyte (sea fennel). Aspalathus linearis (Burm.f.) Dahlg. (rooibos) herbal tea was used as a reference. Sea fennel's tisanes, particularly from leaves, were rich in phenolic compounds and five of them (p-hydroxybenzoic and ferulic acids, epicatechin, pyrocatechol and 4-hydroxybenzaldehyde) were here described in C...
April 17, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28397764/screening-purification-and-characterization-of-anionic-antimicrobial-proteins-from-foeniculum-vulgare
#2
Raid Al Akeel, Ayesha Mateen, Rabbani Syed, Abdullah A Alyousef, Mohammed Rafi Shaik
Foeniculum vulgare Mill., commonly called fennel, is a medicinal plant belonging to the Umbelliferae (Apiaceae) family, and is used in traditional medicine. Antibacterial peptides were isolated using sodium phosphate citrate buffer and, for extraction, cetyltrimethyl ammonium bromide (CTAB) buffer with pH 6, have been employed and antimicrobial activity tested against four reference strains. The extracted protein was subjected to 3 kDa dialysis and separation was carried out by DEAE-ion exchange chromatography and further proteins were identified by 2D gel electrophoresis...
April 8, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28373066/role-of-d-amphetamine-and-d-methamphetamine-as-active-metabolites-of-benzphetamine-evidence-from-drug-discrimination-and-pharmacokinetic-studies-in-male-rhesus-monkeys
#3
Matthew L Banks, Rodney W Snyder, Timothy R Fennell, S Stevens Negus
Benzphetamine is a Schedule III anorectic agent that is a prodrug for d-amphetamine and d-methamphetamine and may have utility as an "agonist" medication for cocaine use disorder treatment. This study evaluated the pharmacokinetic-pharmacodynamic profile of benzphetamine using a drug discrimination procedure in rhesus monkeys. The potency and time course of cocaine-like discriminative stimulus effects were compared for benzphetamine (10-18mg/kg, intramuscular (IM)) and d-amphetamine (0.032-0.32mg/kg, IM) in monkeys (n=3-4) trained to discriminate IM cocaine (0...
March 31, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28352655/panobinostat-acts-synergistically-with-ibrutinib-in-diffuse-large-b-cell-lymphoma-cells-with-myd88-l265-mutations
#4
Patrizia Mondello, Elliott J Brea, Elisa De Stanchina, Eneda Toska, Aaron Y Chang, Myles Fennell, Venkatraman Seshan, Ralph Garippa, David A Scheinberg, José Baselga, Hans-Guido Wendel, Anas Younes
Diffuse large B cell lymphoma (DLBCL) frequently harbors genetic alterations that activate the B cell receptor (BCR) and TLR pathways, which converge to activate NF-κB. While selective inhibition of BTK with ibrutinib causes clinical responses in relapsed DLBCL patients, most responses are partial and of a short duration. Here, we demonstrated that MyD88 silencing enhanced ibrutinib efficacy in DLBCL cells harboring MyD88 L265P mutations. Chemical downregulation of MyD88 expression with HDAC inhibitors also synergized with ibrutinib...
March 23, 2017: JCI Insight
https://www.readbyqxmd.com/read/28344732/autonomic-modulation-in-older-women-using-resistance-exercise-as-a-countermeasure
#5
Hayden Gerhart, Yu Lun Tai, Curtis Fennell, Xián Mayo, J Derek Kingsley
It is unclear if resistance training (RT) can be used to alter declines in autonomic modulation associated with aging. Young women (YW; range 18-25 yrs) and older women (OW; range 50-72 yrs) were compared at baseline. Only OW underwent supervised RT 2 days a week for 12-weeks. Baseline and post-training measurements included heart rate variability (HRV) and complexity (Sample Entropy) to assess autonomic modulation. The 12-weeks of RT consisted of 9 exercises performing 3 sets of 8-12 repetitions. At baseline, group differences in maximal strength, and autonomic modulation were evaluated with a one-way ANOVA with BMI as a covariate...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28341696/a-low-frequency-inactivating-akt2-variant-enriched-in-the-finnish-population-is-associated-with-fasting-insulin-levels-and-type-2-diabetes-risk
#6
Alisa Manning, Heather M Highland, Jessica Gasser, Xueling Sim, Taru Tukiainen, Pierre Fontanillas, Niels Grarup, Manuel A Rivas, Anubha Mahajan, Adam E Locke, Pablo Cingolani, Tune H Pers, Ana Viñuela, Andrew A Brown, Ying Wu, Jason Flannick, Christian Fuchsberger, Eric R Gamazon, Kyle J Gaulton, Hae Kyung Im, Tanya M Teslovich, Thomas W Blackwell, Jette Bork-Jensen, Noël P Burtt, Yuhui Chen, Todd Green, Christopher Hartl, Hyun Min Kang, Ashish Kumar, Claes Ladenvall, Clement Ma, Loukas Moutsianas, Richard D Pearson, John R B Perry, N William Rayner, Neil R Robertson, Laura J Scott, Martijn van de Bunt, Johan G Eriksson, Antti Jula, Seppo Koskinen, Terho Lehtimäki, Aarno Palotie, Olli T Raitakari, Suzanne Br Jacobs, Jennifer Wessel, Audrey Y Chu, Robert A Scott, Mark O Goodarzi, Christine Blancher, Gemma Buck, David Buck, Peter S Chines, Stacey Gabriel, Anette P Gjesing, Christopher J Groves, Mette Hollensted, Jeroen R Huyghe, Anne U Jackson, Goo Jun, Johanne Marie Justesen, Massimo Mangino, Jacquelyn Murphy, Matt Neville, Robert Onofrio, Kerrin S Small, Heather M Stringham, Joseph Trakalo, Eric Banks, Jason Carey, Mauricio O Carneiro, Mark DePristo, Yossi Farjoun, Timothy Fennell, Jacqueline I Goldstein, George Grant, Martin Hrabé de Angelis, Jared Maguire, Benjamin M Neale, Ryan Poplin, Shaun Purcell, Thomas Schwarzmayr, Khalid Shakir, Joshua D Smith, Tim M Strom, Thomas Wieland, Jaana Lindstrom, Ivan Brandslund, Cramer Christensen, Gabriela L Surdulescu, Timo A Lakka, Alex S F Doney, Peter Nilsson, Nicholas J Wareham, Claudia Langenberg, Tibor V Varga, Paul W Franks, Olov Rolandsson, Anders H Rosengren, Vidya S Farook, Farook Thameem, Sobha Puppala, Satish Kumar, Donna M Lehman, Christopher P Jenkinson, Joanne E Curran, Daniel Esten Hale, Sharon P Fowler, Rector Arya, Ralph A DeFronzo, Hanna E Abboud, Ann-Christine Syvänen, Pamela J Hicks, Nicholette D Palmer, Maggie C Y Ng, Donald W Bowden, Barry I Freedman, Tõnu Esko, Reedik Mägi, Lili Milani, Evelin Mihailov, Andres Metspalu, Narisu Narisu, Leena Kinnunen, Lori L Bonnycastle, Amy Swift, Dorota Pasko, Andrew R Wood, João Fadista, Toni I Pollin, Nir Barzilai, Gil Atzmon, Benjamin Glaser, Barbara Thorand, Konstantin Strauch, Annette Peters, Michael Roden, Martina Müller-Nurasyid, Liming Liang, Jennifer Kriebel, Thomas Illig, Harald Grallert, Christian Gieger, Christa Meisinger, Lars Lannfelt, Solomon K Musani, Michael Griswold, Herman A Taylor, Gregory Wilson, Adolfo Correa, Heikki Oksa, William R Scott, Uzma Afzal, Sian-Tsung Tan, Marie Loh, John C Chambers, Jobanpreet Sehmi, Jaspal Singh Kooner, Benjamin Lehne, Yoon Shin Cho, Jong-Young Lee, Bok-Ghee Han, Annemari Käräjämäki, Qibin Qi, Lu Qi, Jinyan Huang, Frank B Hu, Olle Melander, Marju Orho-Melander, Jennifer E Below, David Aguilar, Tien Yin Wong, Jianjun Liu, Chiea-Chuen Khor, Kee Seng Chia, Wei Yen Lim, Ching-Yu Cheng, Edmund Chan, E Shyong Tai, Tin Aung, Allan Linneberg, Bo Isomaa, Thomas Meitinger, Tiinamaija Tuomi, Liisa Hakaste, Jasmina Kravic, Marit E Jørgensen, Torsten Lauritzen, Panos Deloukas, Kathleen E Stirrups, Katharine R Owen, Andrew J Farmer, Timothy M Frayling, Stephen P O'Rahilly, Mark Walker, Jonathan C Levy, Dylan Hodgkiss, Andrew T Hattersley, Teemu Kuulasmaa, Alena Stančáková, Inês Barroso, Dwaipayan Bharadwaj, Juliana Chan, Giriraj R Chandak, Mark J Daly, Peter J Donnelly, Shah B Ebrahim, Paul Elliott, Tasha Fingerlin, Philippe Froguel, Cheng Hu, Weiping Jia, Ronald C W Ma, Gilean McVean, Taesung Park, Dorairaj Prabhakaran, Manjinder Sandhu, James Scott, Rob Sladek, Nikhil Tandon, Yik Ying Teo, Eleftheria Zeggini, Richard M Watanabe, Heikki A Koistinen, Y Antero Kesaniemi, Matti Uusitupa, Timothy D Spector, Veikko Salomaa, Rainer Rauramaa, Colin N A Palmer, Inga Prokopenko, Andrew D Morris, Richard N Bergman, Francis S Collins, Lars Lind, Erik Ingelsson, Jaakko Tuomilehto, Fredrik Karpe, Leif Groop, Torben Jørgensen, Torben Hansen, Oluf Pedersen, Johanna Kuusisto, Gonçalo Abecasis, Graeme I Bell, John Blangero, Nancy J Cox, Ravindranath Duggirala, Mark Seielstad, James G Wilson, Josee Dupuis, Samuli Ripatti, Craig L Hanis, Jose C Florez, Karen L Mohlke, James B Meigs, Markku Laakso, Andrew P Morris, Michael Boehnke, David Altshuler, Mark I McCarthy, Anna L Gloyn, Cecilia M Lindgren
To identify novel coding association signals and facilitate characterization of mechanisms influencing glycemic traits and type 2 diabetes risk, we analyzed 109,215 variants derived from exome array genotyping together with an additional 390,225 variants from exome sequence in up to 39,339 normoglycemic individuals from five ancestry groups. We identified a novel association between the coding variant (p.Pro50Thr) in AKT2 and fasting insulin, a gene in which rare fully penetrant mutations are causal for monogenic glycemic disorders...
March 24, 2017: Diabetes
https://www.readbyqxmd.com/read/28320714/variability-in-trough-total-and-unbound-teicoplanin-concentrations-and-achievement-of-therapeutic-drug-monitoring-targets-in-adult-patients-with-haematological-malignancy
#7
Catherine J Byrne, Jason A Roberts, Brett McWhinney, Jerome P Fennell, Philomena O'Byrne, Evelyn Deasy, Sean Egan, Ronan Desmond, Helen Enright, Sheila A Ryder, Deirdre M D'Arcy, Johnny McHugh
Objectives: To explore the following aspects of teicoplanin use in patients with haematological malignancy: early attainment of target trough concentrations with current high dose teicoplanin regimens; variability in unbound teicoplanin fractions; factors associated with observed total and unbound trough concentrations; efficacy and toxicity; and renal function estimation.Methods: This was a single-centre, prospective study. Trough samples were taken on Days 3, 4, 7 and 10. Total and unbound teicoplanin concentrations were determined using validated HPLC methods...
March 20, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28317747/physicochemical-characteristics-and-pollen-spectrum-of-monofloral-honeys-from-tenerife-spain
#8
Antonio Bentabol Manzanares, Zoa Hernández García, Beatriz Rodríguez Galdón, Elena M Rodríguez-Rodríguez, Carlos Díaz Romero
Physicochemical parameters, sugar composition and botanical origin were determined in four monofloral honeys, chestnut, fennel, tajinaste, and Teide broom honeys, abundantly produced in Tenerife Island. All the parameters were within the established intervals in Europe for each type of honey. Large differences between the four monofloral honeys were observed, being the chestnut honeys with most of differential characteristics. Linear discriminant analysis on the physicochemical parameters and sugar composition allows to distinguishing the four types of honeys analysed...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28288420/molecular-characteristics-of-water-extractable-organic-matter-from-different-composted-biomasses-and-their-effects-on-seed-germination-and-early-growth-of-maize
#9
Hiarhi Monda, Vincenza Cozzolino, Giovanni Vinci, Riccardo Spaccini, Alessandro Piccolo
Four water extractable organic matter (WEOM) were obtained from composts made out of residues of: 1. artichoke (C-CYN), 2. artichoke/fennel (C-CYNF), 3. tomato/woodchips (C-TOM), 4. Municipal solid waste (C-MSW), and their bioactivity was tested for maize seed germination and maize seedling growth. The molecular properties of both original composts and their WEOM were characterized by spectroscopic ((13)C-CPMAS- and (1)H NMR, FTIR-ATR), thermochemolysis-GC/MS, and thermal methods (TGA, DSC). While all WEOM had significant effects on plant growth, CYN-WEOM was the only material that concomitantly increased germination rate and primary and lateral root length of maize seedlings...
March 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28280570/a-method-for-detecting-characteristic-patterns-in-social-interactions-with-an-application-to-handover-interactions
#10
Nikolai W F Bode, Andrew Sutton, Lindsey Lacey, John G Fennell, Ute Leonards
Social interactions are a defining behavioural trait of social animals. Discovering characteristic patterns in the display of such behaviour is one of the fundamental endeavours in behavioural biology and psychology, as this promises to facilitate the general understanding, classification, prediction and even automation of social interactions. We present a novel approach to study characteristic patterns, including both sequential and synchronous actions in social interactions. The key concept in our analysis is to represent social interactions as sequences of behavioural states and to focus on changes in behavioural states shown by individuals rather than on the duration for which they are displayed...
January 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28267636/population-pharmacokinetics-of-teicoplanin-and-attainment-of-pharmacokinetic-pharmacodynamic-targets-in-adult-patients-with-haematological-malignancy
#11
Catherine J Byrne, Jason A Roberts, Brett McWhinney, Sheila A Ryder, Jerome P Fennell, Philomena O'Byrne, Evelyn Deasy, Sean Egan, Ronan Desmond, Helen Enright, Deirdre M D'Arcy, Johnny McHugh
OBJECTIVES: To describe the population pharmacokinetics of teicoplanin in adult haematological malignancy patients receiving higher than standard doses and to perform Monte Carlo simulations to determine dosing regimens associated with optimal teicoplanin concentrations. METHODS: This was a hospital-based clinical trial (EudraCT 2013-004535-72). Nine blood samples were collected on Day 3, plus single trough samples on Days 7 and 10, and 24 and 48 h post last dose...
March 3, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28239718/solvent-control-of-intramolecular-proton-transfer-is-4-hydroxy-3-piperidin-1-ylmethyl-1-naphthaldehyde-a-proton-crane
#12
Y Manolova, H Marciniak, S Tschierlei, F Fennel, F S Kamounah, S Lochbrunner, L Antonov
The solvent dependent excited state dynamics of 4-hydroxy-3-(piperidin-1-ylmethyl)-1-naphthaldehyde (compound 2), a candidate for a molecular switch based on intramolecular proton transfer, was investigated by ultrafast spectroscopy and quantum-chemical calculations. In acetonitrile a mixture of molecules in the enol and zwitterionic proton transfer (PT) form exists in the ground state. However, the zwitterion is the energetically favored one in the electronically excited state. Optical excitation of the enol form results in intramolecular proton transfer and formation of the PT form within 1...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28231113/chemical-composition-antioxidant-and-antimicrobial-activity-of-essential-oils-from-organic-fennel-parsley-and-lavender-from-spain
#13
Irene Marín, Estrella Sayas-Barberá, Manuel Viuda-Martos, Casilda Navarro, Esther Sendra
The aim of this work was to (i) determine the chemical composition of the essential oils of three spices widely cultivated in Spain from organic growth: Foeniculum vulgare, Petroselium crispum, and Lavandula officinalis; (ii) determine the total phenolic content; (iii) determine the antioxidant activity of the essentials oils by means of three different antioxidant tests and (iv) determine the effectiveness of these essentials oils on the inhibition of Listeria innocua CECT 910 and Pseudomonas fluorescens CECT 844...
March 4, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28215625/identification-badge-lanyards-as-infection-control-risk-a-cross-sectional-observation-study-with-epidemiological-analysis
#14
C M Murphy, F Di Ruscio, M Lynskey, J Collins, E McCullough, R Cosgrave, D McDonnell, J Fennell
Staphylococcus aureus cultures from name badge lanyards were phenotypically and genotypically indistinguishable from the wearer's nasal carrier strains by pulsed-field gel electrophoresis and antibiogram. Lanyards had a mean age of 22 months and hygiene was poor with only 9% ever having been laundered. Molecular analysis showed that 26% of S. aureus nasal carriers shared an indistinguishable strain on their lanyard. Lanyards should not be recommended for staff in frontline clinical care.
January 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28208803/barriers-to-seeking-help-for-skin-cancer-detection-in-rural-australia
#15
Kate M Fennell, Kimberley Martin, Carlene J Wilson, Camilla Trenerry, Greg Sharplin, James Dollman
This study explores rural South Australians' barriers to help-seeking for skin cancer detection. A total of 201 randomly selected rural adults (18-94 years, 66% female) were presented with a skin-cancer-related scenario via telephone and were asked the extent to which various barriers would impede their help-seeking, based on an amended version of the Barriers to Help-Seeking Scale. Older (≥63 years) and less educated participants endorsed barriers more strongly than their younger, more educated counterparts in the following domains; "Concrete barriers and distrust of caregivers", "Emotional control", "Minimising problem and Normalisation", "Need for control and self-reliance" (every domain other than "Privacy")...
February 13, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/28181494/microenvironment-derived-factors-driving-metastatic-plasticity-in-melanoma
#16
Isabella S Kim, Silja Heilmann, Emily R Kansler, Yan Zhang, Milena Zimmer, Kajan Ratnakumar, Robert L Bowman, Theresa Simon-Vermot, Myles Fennell, Ralph Garippa, Liang Lu, William Lee, Travis Hollmann, Joao B Xavier, Richard M White
Cellular plasticity is a state in which cancer cells exist along a reversible phenotypic spectrum, and underlies key traits such as drug resistance and metastasis. Melanoma plasticity is linked to phenotype switching, where the microenvironment induces switches between invasive/MITF(LO) versus proliferative/MITF(HI) states. Since MITF also induces pigmentation, we hypothesize that macrometastatic success should be favoured by microenvironments that induce a MITF(HI)/differentiated/proliferative state. Zebrafish imaging demonstrates that after extravasation, melanoma cells become pigmented and enact a gene expression program of melanocyte differentiation...
February 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28172469/qubic-a-bioconductor-package-for-qualitative-biclustering-analysis-of-gene-co-expression-data
#17
Yu Zhang, Juan Xie, Jinyu Yang, Anne Fennell, Chi Zhang, Qin Ma
No abstract text is available yet for this article.
February 1, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28127770/the-epicenter-of-effectiveness-and-efficiency-in-health-care-delivery-the-evolving-u-s-health-workforce
#18
Michelle M Washko, Mary L Fennell
No abstract text is available yet for this article.
February 2017: Health Services Research
https://www.readbyqxmd.com/read/28125179/an-approach-to-optimise-therapeutic-vancomycin-dosage-in-a-haemodialysis-population
#19
H Gunning, G Taylor, A Smyth, G Mellotte, J Fennell, P Murphy, P Lavin, C Wall
Haemodialysis patients are at risk of gram-positive bacteraemia and commonly require intravenous vancomycin. Intravenously administered vancomycin is primarily excreted by the kidney and exhibits complex pharmacokinetics in haemodialysis patients; achieving therapeutic levels can be challenging. An audit in our unit showed current practises of vancomycin administration resulted in a high proportion of sub-therapeutic levels. A new protocol was developed with fixed weight-based loading and subsequent dosing guided by pre-dialysis levels, target levels were 10-20mg/L...
October 12, 2016: Irish Medical Journal
https://www.readbyqxmd.com/read/28124812/an-insight-on-salting-out-assisted-liquid-liquid-extraction-for-phytoanalysis
#20
Inês M Valente, Manuela M Moreira, Pâmela Neves, Thiago da Fé, Luís M Gonçalves, Paulo J Almeida, José A Rodrigues
INTRODUCTION: Salting-out assisted liquid-liquid extraction (SALLE) is a technique that, although simple and not requiring any complex equipment, is very powerful and versatile. It has obtained growing interest in bioanalysis particularly when combined with chromatographic techniques. OBJECTIVES: Herein, fennel seeds (Foeniculum vulgare Mill.) were used as a case-study to show the application of SALLE in phytochemical analysis. MATERIAL AND METHODS: SALLE combined with HPLC-UV-MS/MS and GC-MS...
January 26, 2017: Phytochemical Analysis: PCA
keyword
keyword
53890
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"