keyword
MENU ▼
Read by QxMD icon Read
search

Bacteremia

keyword
https://www.readbyqxmd.com/read/29471109/extensively-drug-resistant-acinetobacter-baumannii-bacteremias-in-a-multidisciplinary-intensive-care-unit-during-a-6-year-period-risk-factors-for-fulminant-sepsis
#1
M Katsiari, A Mavroidi, E D Platsouka, C Nikolaou
OBJECTIVES: The aim of the present study was to determine potential host-, pathogen-, infection- and treatment-related risk factors that might predict a fulminant, fatal course of bacteremia caused extensively drug-resistant A. baumannii (XDR Aba). METHODS: Eighty-seven patients with monomicrobial growth of XDR Aba in blood cultures within a 6-year period were studied. Patients were divided into three groups, according to ICU outcome. Group A (n=40) consisted of patients who survived, Group B (n=10) included patients with fulminant sepsis that died early (<48h), whereas Group C (n=37) included patients that died later (> 48h) after the onset of bacteremia...
February 19, 2018: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29470836/role-of-vancomycin-minimum-inhibitory-concentrations-by-modified-population-analysis-profile-method-and-clinical-outcomes-in-high-inoculum-methicillin-resistant-staphylococcus-aureus-infections
#2
Trang D Trinh, Evan J Zasowski, Kimberly C Claeys, Anthony M Casapao, Matthew Compton, Abdalhamid Lagnf, Shravya D Kidambi, Donald P Levine, Michael J Rybak
INTRODUCTION: Vancomycin remains the standard of care for invasive methicillin-resistant Staphylococcus aureus (MRSA) infections. Treatment failures from heteroresistant vancomycin-intermediate subpopulations (hVISA) are challenging to detect. Minimum inhibitory concentrations (MIC) identified by modified population analysis profile (PAP) is an alternative testing method. The aim of this study was to evaluate the role of PAP MIC on vancomycin failures in two high inoculum infections: MRSA infective endocarditis and pneumonia...
February 22, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29468780/efficacy-analysis-of-routine-catheter-tip-cultures-in-a-neonatal-intensive-care-unit
#3
Taito Kitano, Kumiko Takagi, Ikuyo Arai, Hajime Yasuhara, Reiko Ebisu, Ayako Ohgitani, Daisuke Kitagawa, Miyako Oka, Kazue Masuo, Hideki Minowa
OBJECTIVES: Although routine catheter tip cultures are not recommended, previous reports have indicated that some cases of colonization, such as with S. aureus, can lead to subsequent bacteremia. To evaluate the safety of colonized cases without antimicrobial treatment, as well as the effectiveness of routine catheter tip cultures in the neonatal intensive care unit (NICU), we performed a retrospective data analysis in a Japanese community hospital. METHODS: We reviewed all peripherally inserted central venous catheter tip culture results from the NICU ward between April 2012 and June 2017 to determine whether they had antimicrobial treatments or subsequent infections...
February 22, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29466395/dynamics-of-monocytic-hla-dr-expression-differs-between-bacterial-etiologies-during-the-course-of-bloodstream-infection
#4
Sara Cajander, Gunlög Rasmussen, Elisabet Tina, Anders Magnuson, Bo Söderquist, Jan Källman, Kristoffer Strålin
OBJECTIVE: In the pathogenesis of sepsis, activation of both pro- and anti-inflammatory responses are key components, but knowledge is lacking on the association between bacterial etiology and development of dysregulated responses with sustained immunosuppression. The aim of this study was to evaluate how the immunosupression marker HLA-DR on monocytes (mHLA-DR) is associated with bacterial etiology and markers of inflammation during the clinical trajectory of bloodstream infection (BSI)...
2018: PloS One
https://www.readbyqxmd.com/read/29463249/continued-in-vitro-cefazolin-susceptibility-in-methicillin-susceptible-staphylococcus-aureus
#5
Benjamin H Gern, Alexander L Greninger, Scott J Weissman, Jennifer R Stapp, Yue Tao, Xuan Qin
OBJECTIVES: In vitro trends of cefazolin and ceftriaxone susceptibilities from pediatric clinical isolates of methicillin-susceptible Staphylococcus aureus (MSSA) between 2011 and 2016 were analyzed for surveillance. METHODS: Our laboratory continues to use agar disk diffusion for staphylococcal susceptibilities applying Clinical Laboratory Standard Institute's 2012 breakpoints. RESULTS: A total of 3992 MSSA clinical isolates in the last 6 years were analyzed for their in vitro cefazolin and ceftriaxone susceptibilities...
February 20, 2018: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29462291/risk-factors-for-recurrent-helicobacter-cinaedi-bacteremia-and-the-efficacy-of-selective-digestive-decontamination-with-kanamycin-to-prevent-recurrence
#6
Hideki Araoka, Masaru Baba, Chikako Okada, Muneyoshi Kimura, Tomoaki Sato, Yutaka Yatomi, Kyoji Moriya, Akiko Yoneyama
Background: Previous studies suggest that Helicobacter cinaedi can cause recurrent bacteremia. This study aimed to elucidate the risk factors for recurrent H. cinaedi bacteremia and explore the efficacy of selective digestive decontamination (SDD) as a preventive measure. Methods: We retrospectively reviewed the medical records of all patients with H. cinaedi bacteremia between March 2009 and December 2016 at two Japanese hospitals. Results: We identified 168 patients with H...
February 15, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29462106/prevalence-of-occult-bacteremia-in-infants-with-very-high-fever-without-a-source
#7
Iker Gangoiti, Elva Rodriguez, Ane Zubizarreta, Javier Benito, Santiago Mintegi
We carried out a prospective registry-based cohort study at the emergency department of 363 previously healthy well-appearing infants aged 3-24 months old with fever without a source ≥ 40.5°C based on local protocol. Four were diagnosed with occult bacteremia (1.1%, 95% CI 0-2.2). Recommendations for non-testing for occult bacteremia screening in these children may have to be re-considered when fever ≥40.5°C. Larger studies are needed to confirm these results.
February 16, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29460786/appropriateness-of-peripheral-parenteral-nutrition-use-in-adult-patients-at-an-academic-medical-center
#8
David Sugrue, Andrew S Jarrell, Rachel Kruer, Stephanie Davis, Dachelle Johnson, Evelyn Tsui, Sukyee Snyder, Jessica Crow
BACKGROUND & AIMS: Current evidence and guidelines identify patient populations who may benefit from parenteral nutrition. Peripheral parenteral nutrition (PPN) may be indicated for a subset of patients; however, PPN therapy carries a risk of associated adverse effects. The purpose of this project was to assess appropriateness of current PPN prescribing practices at an academic medical center to determine whether additional guidance and oversight may be beneficial. METHODS: Adult patients admitted from August 1, 2015 to November 30, 2015 with at least one order of PPN administered were included...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29457569/hospital-onset-mrsa-bacteremia-rates-are-significantly-correlated-with-sociodemographic-factors-a-step-toward-risk-adjustment
#9
Joshua T Freeman, Matthew R Blakiston, Deverick J Anderson
The correlations between census-derived sociodemographic variables and hospital-onset methicillin-resistant Staphylococcus aureus bacteremia (HO-MRSAB) rates were examined at the US state level. On multivariable analysis, only percent African American remained statistically significant. This finding highlights an important disparity and suggests that risk adjustment is needed when comparing HO-MRSAB rates among US states. Infect Control Hosp Epidemiol 2018;1-3.
February 19, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29457119/effects-of-glucose-insulin-infusion-during-major-oral-and-maxillofacial-surgery-on-postoperative-complications-and-outcomes
#10
Akina Tohya, Atsushi Kohjitani, Sachi Ohno, Kaoru Yamashita, Yozo Manabe, Mitsutaka Sugimura
Background: Secretion of hormones, which antagonize the action of insulin, is facilitated in response to surgery, and acute resistance to the action of insulin develops. Our aim is to elucidate the effects of intraoperative glycemic control by glucose-insulin (GI) infusion on postoperative complications and outcomes in major oral and maxillofacial surgery. Findings: Thirty patients aged ≥ 60 years undergoing a radical operation of oral malignant tumors with tissue reconstruction (≥ 8 h) were analyzed...
2018: JA Clin Rep
https://www.readbyqxmd.com/read/29455206/a-potential-mechanism-for-immune-suppression-by-beta-adrenergic-receptor-stimulation-following-traumatic-injury
#11
Nicholas J Shubin, Tam N Pham, Kristan Lea Staudenmayer, Brodie A Parent, Qian Qiu, Grant E O'Keefe
BACKGROUND: β-Adrenergic agents suppress inflammation and may play an important role in posttraumatic infections. Mechanisms may include inhibition of MAP kinase signaling. We sought to determine whether MKP-1 contributed to catecholamine suppression of innate immunity and also wanted to know whether early catecholamine treatment after traumatic injury increases the risk of later nosocomial infection. METHODS: We performed experiments using THP-1 cells and peripheral blood mononuclear cells from healthy individuals...
February 16, 2018: Journal of Innate Immunity
https://www.readbyqxmd.com/read/29454228/obturator-internus-muscle-abscess-caused-by-methicillin-resistant-staphylococcus-aureus-in-an-adult-a-case-report
#12
Akinori Maeda, Isaku Saku, Shotaro Kanda, Kazuo Saita, Toru Akiyama
INTRODUCTION: Obturator internus muscle (OIM) abscess is a rare condition, usually affecting children after trauma or muscular effort. Blood cultures always yield positive findings, with Staphylococcus aureus being the most common culprit. There are few reports in adults. PRESENTATION OF CASE: We report a case of OIM abscess in an adult. A 24-year-old male was admitted to our hospital because of right hip pain and fever. He was diagnosed with OIM abscess, and methicillin-resistant Staphylococcus aureus (MRSA) was detected on bacterial examination...
February 9, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29453766/spondylodiscitis-due-to-aerococcus-urinae-and-literature-review
#13
Estelle Rougier, Antoine Braud, Xavier Argemi, Nicolas Lefebvre, Daniel Christmann, Yves Hansmann, Nawal Douiri
INTRODUCTION: Aerococccus urinae (AU) is a pathogen mainly identified in male urinary tract infections and responsible for bacteremia and endocarditis. To the best of our knowledge, there are only five patients with osteomyelitis due to AU described in the literature. All of them had urinary tract disease or systemic conditions such as diabetes, and two were associated with an endocarditis. CASE REPORT: We described the first case of isolated spondylodiscitis without general or local predisposing condition, excepted age > 65 years...
February 16, 2018: Infection
https://www.readbyqxmd.com/read/29452598/7-versus-14-days-of-antibiotic-treatment-for-critically-ill-patients-with-bloodstream-infection-a-pilot-randomized-clinical-trial
#14
Nick Daneman, Asgar H Rishu, Ruxandra Pinto, Pierre Aslanian, Sean M Bagshaw, Alex Carignan, Emmanuel Charbonney, Bryan Coburn, Deborah J Cook, Michael E Detsky, Peter Dodek, Richard Hall, Anand Kumar, Francois Lamontagne, Francois Lauzier, John C Marshall, Claudio M Martin, Lauralyn McIntyre, John Muscedere, Steven Reynolds, Wendy Sligl, Henry T Stelfox, M Elizabeth Wilcox, Robert A Fowler
BACKGROUND: Shorter-duration antibiotic treatment is sufficient for a range of bacterial infections, but has not been adequately studied for bloodstream infections. Our systematic review, survey, and observational study indicated equipoise for a trial of 7 versus 14 days of antibiotic treatment for bloodstream infections; a pilot randomized clinical trial (RCT) was a necessary next step to assess feasibility of a larger trial. METHODS: We conducted an open, pilot RCT of antibiotic treatment duration among critically ill patients with bloodstream infection across 11 intensive care units (ICUs)...
February 17, 2018: Trials
https://www.readbyqxmd.com/read/29452323/burr-hole-surgery-for-chronic-subdural-hematoma-with-extensive-scalp-burn-a-case-report
#15
Eijiro Echizen, Kei Miyata, Ken Yamashita, Takeshi Mikami, Eichi Narimatsu, Nobuhiro Mikuni
BACKGROUND: Neurosurgical intervention for a patient with an extensive scalp burn is rare, but it might be associated with the high risk of surgical site infection. CASE DESCRIPTION: An 80-year-old man had a severe and extensive scalp burn. A chronic subdural hematoma (CSDH) was observed on a head CT for the assessment of bacteremia during treatment in the intensive care unit. To evaluate whether the CSDH might underlie his prolonged fever and sepsis pathology, we urgently evacuated the hematoma using one burr hole...
February 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29451055/early-discontinuation-of-empirical-antibacterial-therapy-in-febrile-neutropenia-the-antibiostop-study
#16
Lenaïg Le Clech, Jean-Philippe Talarmin, Marie-Anne Couturier, Jean-Christophe Ianotto, Christophe Nicol, Ronan Le Calloch, Stéphanie Dos Santos, Pascal Hutin, Didier Tandé, Virginie Cogulet, Christian Berthou, Gaëlle Guillerm
INTRODUCTION: Immediate empirical antibiotic therapy is mandatory in febrile chemotherapy-induced neutropenia, but its optimal duration is unclear, especially in patients with fever of unknown origin (FUO). OBJECTIVES: The primary objective of this 20-month prospective observational study was to evaluate the feasibility and safety of short-term antibiotic treatment in afebrile or febrile patients exhibiting FUO, irrespective of their neutrophil count. The secondary objective was to describe the epidemiology of all episodes of febrile neutropenia...
February 16, 2018: Infectious Diseases
https://www.readbyqxmd.com/read/29448851/salvage-tigecycline-in-high-risk-febrile-neutropenic-patients-with-hematological-malignancies-a-prospective-multicenter-study
#17
Xin-Ping Zhou, Xiu-Jin Ye, Jian-Ping Shen, Jian-Ping Lan, Hui-Fang Jiang, Jin Zhang, Xue-Jin Zhang, Li Li, Shen-Xian Qian, Hong-Yan Tong
The purpose of this prospective, multi-center study was to examine the efficacy and safety of tigecycline as empirical treatment in neutropenic patients with hematological malignancies who failed to respond to first-line antibiotics. A total of 125 patients with persistent fever (>72 h) despite first-line antibiotics received empirical treatment with tigecycline (loading dose of 100 mg, followed by 50 mg every 12 h). The use of other antimicrobial agents was not restricted. Treatment success rate was 68...
February 16, 2018: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/29445800/acoustic-separation-in-plastic-microfluidics-for-rapid-detection-of-bacteria-in-blood-using-engineered-bacteriophage
#18
P Dow, K Kotz, S Gruszka, J Holder, J Fiering
A more effective treatment of bacteremia requires a diagnostic platform that is both sensitive, accurate and rapid. Currently, clinical laboratory techniques require growth of bacteria prior to diagnosis, take days to complete, and leave empiric therapy and broad spectrum antibiotics as the only option at the onset of treatment. In order to bypass this growth requirement, we engineered a system that purifies bacteria from blood to improve performance in a bacteriophage-based luminescence assay. To perform the purification, we used acoustophoresis in plastic microfluidic chips, enabling future development into a low cost point-of-care system...
February 15, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29441942/risk-factors-for-the-failure-of-treatment-of-pseudomonas-aeruginosa-bacteremia-in-critically-ill-patients
#19
S Yoshida, K Suzuki, A Suzuki, H Okada, T Niwa, R Kobayashi, N Murakami, S Ogura, Y Itoh
Pseudomonas aeruginosa bacteremia is associated with high morbidity and mortality in critically ill patients. In this study, we assessed risk factors for clinical failure of first definitive therapy for P. aeruginosa bacteremia in critically ill patients. All patients with P. aeruginosa bacteremia who entered the intensive care unit in Gifu University Hospital from January 2006 to December 2015 were retrospectively identified from electronic records. Risk factors associated with clinical failure of the first definitive therapy for P...
July 3, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29441651/invasive-pneumococcal-infections-in-pediatric-liver-small-bowel-pancreas-transplant-recipients
#20
Hanh D Vo, Diana F Florescu, Cindy R Brown, Heather E Chambers, David F Mercer, Luciano M Vargas, Wendy J Grant, Alan N Langnas, Ruben E Quiros-Tejeira
Children undergoing LSBPTx are at increased risk of IPI due to splenectomy. We aimed to describe the clinical features and outcomes of IPI in pediatric LSBPTx recipients. Between 2008 and 2016, 122 LSBPTx children at our center were retrospectively reviewed. Nine patients had 12 episodes of IPI; the median age at first infection was 3.5 years (range: 1.5-7.1 years). The median time from transplant to first infection was 3 years (range: 0.8-5.8 years). Clinical presentation included as follows: pneumonia (n = 1), bacteremia/sepsis (n = 7), pneumonia with sepsis (n = 1), meningitis with sepsis (n = 2), pneumonia and meningitis with sepsis (n = 1)...
February 13, 2018: Pediatric Transplantation
keyword
keyword
5389
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"