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Functional electrical stimulation

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https://www.readbyqxmd.com/read/29785045/an-initial-study-on-the-effect-of-functional-electrical-stimulation-in-erectile-dysfunction-a-randomized-controlled-trial
#1
Cristiane Carboni, Alexandre Fornari, Karoline C Bragante, Marcio A Averbeck, Patrícia Vianna da Rosa, Rodrigo Della Mea Plentz
Erectile dysfunction (ED) affects approximately 150 million men worldwide. Functional electrical stimulation (FES) therapy has shown a high regenerative capacity for smooth muscle cells and, therefore, is being increasingly adopted. FES can be a beneficial treatment option when the cause of ED is related to degeneration of cavernous smooth muscle. To evaluate the impact of FES on erectile function in men with erectile dysfunction. Twenty-two patients with ED participated in this randomized clinical trial. Participants were randomly assigned to two groups: intervention (IG) or control (CG)...
May 22, 2018: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29781580/neuromuscular-electrical-stimulation-compared-to-volitional-exercise-in-improving-muscle-function-in-rheumatoid-arthritis-a-randomized-pilot-study
#2
Sara R Piva, Samannaaz S Khoja, Frederico G S Toledo, Mary Chester Wasko, G Kelley Fitzgerald, Bret H Goodpaster, Clair N Smith, Anthony Delitto
OBJECTIVES: To compare the feasibility and effectiveness of Neuromuscular Electrical Stimulation (NMES) with high-intensity volitional resistance training in improving muscle structure and function, and physical function in patients with rheumatoid arthritis (RA). We also described pre- and post-intervention values of myocyte characteristics. METHODS: Two-group single-blinded pilot randomized study in adults with RA. Participants were assigned to 36 sessions over 16 weeks of NMES (n=31) or volitional training (n=28)...
May 21, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29781517/a-homozygous-scn5a-mutation-associated-with-atrial-standstill-and-sudden-death
#3
Reina Bianca Tan, Ivan Gando, Lei Bu, Frank Cecchin, William Coetzee
BACKGROUND: Atrial standstill is an arrhythmogenic condition characterized by the absence of spontaneous electrical and mechanical atrial activity or in response to stimulation. There are few reported familial cases which have been associated with SCN5A mutations co-segregating with GJA5 or RYR2 however isolated SCN5A mutations are rare. OBJECTIVE: The purpose of this study was to determine the clinical and biophysical consequence of a novel SCN5A mutation identified in a family with progressive atrial standstill and sudden death...
May 21, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29780966/electro-tactile-stimulation-ets-enhances-cochlear-implant-mandarin-tone-recognition
#4
Juan Huang, Janice Chang, Fan-Gang Zeng
Objective: Electro-acoustic stimulation (EAS) is an effective method to enhance cochlear-implant performance in individuals who have residual low-frequency acoustic hearing. To help the majority of cochlear implant users who do not have any functional residual acoustic hearing, electro-tactile stimulation (ETS) may be used because tactile sensation has a frequency range and perceptual capabilities similar to that produced by acoustic stimulation in the EAS users. Methods: Following up the first ETS study showing enhanced English sentence recognition in noise,1 the present study evaluated the effect of ETS on Mandarin tone recognition in noise in two groups of adult Mandarin-speaking individuals...
December 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29780316/resonance-analysis-as-a-tool-for-characterizing-functional-division-of-layer-5-pyramidal-neurons
#5
Melvin A Felton, Alfred B Yu, David L Boothe, Kelvin S Oie, Piotr J Franaszczuk
Evidence suggests that layer 5 pyramidal neurons can be divided into functional zones with unique afferent connectivity and membrane characteristics that allow for post-synaptic integration of feedforward and feedback inputs. To assess the existence of these zones and their interaction, we characterized the resonance properties of a biophysically-realistic compartmental model of a neocortical layer 5 pyramidal neuron. Consistent with recently published theoretical and empirical findings, our model was configured to have a "hot zone" in distal apical dendrite and apical tuft where both high- and low-threshold Ca2+ ionic conductances had densities 1-2 orders of magnitude higher than anywhere else in the apical dendrite...
2018: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/29779963/action-potential-initiation-propagation-and-cortical-invasion-in-the-hyperdirect-pathway-during-subthalamic-deep-brain-stimulation
#6
Ross W Anderson, AmirAli Farokhniaee, Kabilar Gunalan, Bryan Howell, Cameron C McIntyre
BACKGROUND: High frequency (∼130 Hz) deep brain stimulation (DBS) of the subthalamic region is an established clinical therapy for the treatment of late stage Parkinson's disease (PD). Direct modulation of the hyperdirect pathway, defined as cortical layer V pyramidal neurons that send an axon collateral to the subthalamic nucleus (STN), has emerged as a possible component of the therapeutic mechanisms. However, numerous questions remain to be addressed on the basic biophysics of hyperdirect pathway stimulation...
May 12, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29777714/efficiency-of-neuromuscular-electrical-stimulation-and-transcutaneous-nerve-stimulation-on-hemiplegic-shoulder-pain-a-prospective-randomized-controlled-trial
#7
Meimei Zhou, Fang Li, Weibo Lu, Junfa Wu, Song Pei
OBJECTIVE: To compare the efficacy of neuromuscular electrical stimulation (NMES) and transcutaneous nerve stimulation (TENS) on hemiplegic shoulder pain (HSP). DESIGN: This is a prospective randomized controlled trial (RCT). SETTING: A total of 184 HSP patients, aged 18-80 years, were recruited in the Rehabilitation Hospital from February 2014 to July 2016. The Ethics approval was obtained from the Institutional Review Board of the Hospital...
May 16, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29777277/impact-of-muscle-atrophy-on-bone-metabolism-and-bone-strength-implications-for-muscle-bone-crosstalk-with-aging-and-disuse
#8
REVIEW
T Bettis, B-J Kim, M W Hamrick
Bone fractures in older adults are often preceded by a loss of muscle mass and strength. Likewise, bone loss with prolonged bed rest, spinal cord injury, or with exposure to microgravity is also preceded by a rapid loss of muscle mass. Recent studies using animal models in the setting of hindlimb unloading or botulinum toxin (Botox) injection also reveal that muscle loss can induce bone loss. Moreover, muscle-derived factors such as irisin and leptin can inhibit bone loss with unloading, and knockout of catabolic factors in muscle such as the ubiquitin ligase Murf1 or the myokine myostatin can reduce osteoclastogenesis...
May 18, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29770490/functional-magnetic-resonance-electrical-impedance-tomography-fmreit-sensitivity-analysis-using-an-active-bidomain-finite-element-model-of-neural-tissue
#9
Rosalind J Sadleir, Fanrui Fu, Munish Chauhan
PURPOSE: A direct method of imaging neural activity was simulated to determine typical signal sizes. METHODS: An active bidomain finite-element model was used to estimate approximate perturbations in MR phase data as a result of neural tissue activity, and when an external MR electrical impedance tomography imaging current was added to the region containing neural current sources. RESULTS: Modeling-predicted, activity-related conductivity changes should produce measurable differential phase signals in practical MR electrical impedance tomography experiments conducted at moderate resolution at noise levels typical of high field systems...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29768013/synergistic-effects-of-electrical-stimulation-and-aligned-nanofibrous-microenvironment-on-growth-behaviour-of-mesenchymal-stem-cells
#10
Lin Jin, Bin Hu, Zhanrong Li, Jingguo Li, Yanzheng Gao, Zhenling Wang, Jianhua Hao
Incontrollable cellular growth behaviour is a significant issue that severely affects the functional tissue formation and cellular protein expression. Development of natural extracellular matrix (ECM) like biomaterials to present microenvironment cues for the regulation of cell responses can effectively overcome this problem. The external simulation and topological characteristics as guiding cues are capable of providing diverse influences on cellular growth. Herein, we developed two dimensional aligned conductive nanofibers (2D-ACNFs) by electrospinning process and surface polymerization, and provided the effects of both alignment and electrical stimulation (ES) on cellular response of human mesenchymal cells (hMSCs)...
May 16, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29767958/distinguishing-between-deep-trapping-transients-of-electrons-and-holes-in-tio2-nanotube-arrays-using-planar-microwave-resonator-sensor
#11
Mohammad H Zarifi, Benjamin Daniel Wiltshire, Najia Mahdi, Karthik Shankar, Mojgan Daneshmand
A large signal DC bias and a small signal microwave bias were simultaneously applied to TiO2 nanotube membranes mounted on a planar microwave resonator. The DC bias modulated the electron concentration in the TiO2 nanotubes, and was varied between 0 and 120 V in this study. Transients immediately following the application and removal of DC bias were measured by monitoring the S-parameters of the resonator as a function of time. The DC bias stimulated Poole-Frenkel type trap-mediated electrical injection of excess carriers into TiO2 nanotubes which resulted in a near constant resonant frequency but a pronounced decrease in the microwave amplitude due to free electron absorption...
May 16, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29766458/cerebellar-stimulation-evoked-prefrontal-electrical-synchrony-is-modulated-by-gaba
#12
Xiaoming Du, Laura M Rowland, Ann Summerfelt, Fow-Sen Choa, George F Wittenberg, Krista Wisner, Andrea Wijtenburg, Joshua Chiappelli, Peter Kochunov, L Elliot Hong
Cerebellar-prefrontal connectivity has been recognized as important for behaviors ranging from motor coordination to cognition. Many of these behaviors are known to involve excitatory or inhibitory modulations from the prefrontal cortex. We used cerebellar transcranial magnetic stimulation (TMS) with simultaneous electroencephalography (EEG) to probe cerebellar-evoked electrical activity in prefrontal cortical areas and used magnetic resonance spectroscopy (MRS) measures of prefrontal GABA and glutamate levels to determine if they are correlated with those potentials...
May 15, 2018: Cerebellum
https://www.readbyqxmd.com/read/29766393/linear-feature-projection-based-real-time-decoding-of-limb-state-from-dorsal-root-ganglion-recordings
#13
Sungmin Han, Jun-Uk Chu, Jong Woong Park, Inchan Youn
Proprioceptive afferent activities recorded by a multichannel microelectrode have been used to decode limb movements to provide sensory feedback signals for closed-loop control in a functional electrical stimulation (FES) system. However, analyzing the high dimensionality of neural activity is one of the major challenges in real-time applications. This paper proposes a linear feature projection method for the real-time decoding of ankle and knee joint angles. Single-unit activity was extracted as a feature vector from proprioceptive afferent signals that were recorded from the L7 dorsal root ganglion during passive movements of ankle and knee joints...
May 15, 2018: Journal of Computational Neuroscience
https://www.readbyqxmd.com/read/29763748/right-hemisphere-cognitive-functions-from-clinical-and-anatomical-bases-to-brain-mapping-during-awake-craniotomy-part-i-clinical-and-functional-anatomy
#14
REVIEW
Florian Bernard, Jean-Michel Lemée, Aram Ter Minassian, Philippe Menei
The non-dominant hemisphere (usually the right) is responsible for primary cognitive functions such as visuo-spatial and social cognition. Awake surgery using direct electrical stimulation for right cerebral tumor removal remains challenging due to the complexity of the functional anatomy and difficulties in adapting standard bedside tasks to awake surgery conditions. An understanding of semiology and anatomical bases, along with an analysis of the available cognitive tasks for visuo-spatial and social cognition per operative mapping will allow neurosurgeons to better appreciate the functional anatomy of the right hemisphere and its relevance to tumor surgery...
May 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29759543/long-term-outcomes-of-catheter-ablation-of-electrical-storm-in-nonischemic-dilated-cardiomyopathy-compared-with-ischemic-cardiomyopathy
#15
Daniele Muser, Jackson J Liang, Rajeev K Pathak, Silvia Magnani, Simon A Castro, Tatsuya Hayashi, Fermin C Garcia, Gregory E Supple, Michael P Riley, David Lin, Sanjay Dixit, Erica S Zado, David S Frankel, David J Callans, Francis E Marchlinski, Pasquale Santangeli
OBJECTIVES: The goal of this study was to determine the long-term outcomes of catheter ablation (CA) of electrical storm in patients with nonischemic dilated cardiomyopathy (NIDCM) compared with patients with ischemic cardiomyopathy (ICM). BACKGROUND: CA of ventricular tachycardia (VT) electrical storm has been shown to improve VT-free survival in patients with ICM. Data on the outcomes of CA of electrical storm in patients with NIDCM are insufficient. METHODS: The study included 267 consecutive patients with NIDCM (n = 71; ejection fraction 32 ± 14%) and ICM (n = 196; ejection fraction 28 ± 12%)...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29756513/self-directed-therapy-programmes-for-arm-rehabilitation-after-stroke-a-systematic-review
#16
Ruth H Da-Silva, Sarah A Moore, Christopher I Price
AIM: To investigate the effectiveness of self-directed arm interventions in adult stroke survivors. METHODS: A systematic review of Medline, EMBASE, CINAHL, SCOPUS and IEEE Xplore up to February 2018 was carried out. Studies of stroke arm interventions were included where more than 50% of the time spent in therapy was initiated and carried out by the participant. Quality of the evidence was assessed using the Cochrane risk of bias tool. RESULTS: A total of 40 studies ( n = 1172 participants) were included (19 randomized controlled trials (RCTs) and 21 before-after studies)...
May 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29755230/scoliosis-conservative-treatment-a-review-of-literature
#17
REVIEW
Mohammad Taghi Karimi, Timon Rabczuk
Background: Scoliosis is defined as lateral curvature of the spine which is also associated with a change in the curves in sagittal plane and vertebral rotation. Various types of conservative treatment approaches have been recommended for the patients with scoliosis. The aim of this review article was to introduce the various methods of conservative treatment which can be used for the patients with scoliosis. Methods: A search was done in some databases including PubMed, ISI Web of knowledge, Google scholar, Ebsco, Embasco, and Scopus...
January 2018: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29754900/burst-firing-in-bee-gustatory-neurons-prevents-adaptation
#18
Ashwin Miriyala, Sébastien Kessler, F Claire Rind, Geraldine A Wright
Animals detect changes in the environment using modality-specific, peripheral sensory neurons. The insect gustatory system encodes tastant identity and concentration through the independent firing of gustatory receptor neurons (GRNs) that spike rapidly at stimulus onset and quickly adapt. Here, we show the first evidence that concentrated sugar evokes a temporally structured burst pattern of spiking involving two GRNs within the gustatory sensilla of bumblebees. Bursts of spikes resulted when a sucrose-activated GRN was inhibited by another GRN at a frequency of ∼22 Hz during the first 1 s of stimulation...
May 1, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29754449/transcranial-alternating-current-stimulation-modulates-auditory-temporal-resolution-in-elderly-people
#19
Alina Baltus, Johannes Vosskuhl, Cindy Boetzel, Christoph Siegfried Herrmann
Recent research provides evidence for a functional role of brain oscillations for perception. For example, auditory temporal resolution seems to be linked to individual gamma frequency of auditory cortex. Individual gamma frequency not only correlates with performance in between-channel gap detection tasks but can be modulated via auditory transcranial alternating current stimulation. Modulation of individual gamma frequency is accompanied by an improvement in gap detection performance. Aging changes electrophysiological frequency components and sensory processing mechanisms...
May 13, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29754008/vascular-endothelial-injury-in-severe-fever-with-thrombocytopenia-syndrome-caused-by-the-novel-bunyavirus
#20
Xiao-Kun Li, Shao-Fei Zhang, Wen Xu, Bo Xing, Qing-Bin Lu, Pan-He Zhang, Hao Li, Li Zhang, Wen-Cong Zhang, Wei-Wei Chen, Wu-Chun Cao, Wei Liu
Severe fever with thrombocytopenia syndrome virus (SFTSV) infection typically causes acute fever, thrombocytopenia and leucopenia, presenting with a high case fatality rate. The pathogenesis of SFTSV infection, however, is not well described. It was hypothesized that endothelial dysfunction might play part in the disease process. In current study, we retrospectively analyzed the clinical manifestations among a large group of confirmed SFTS cases and found evidence of plasma leakage and vascular endothelial injury...
May 10, 2018: Virology
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