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https://www.readbyqxmd.com/read/28335574/proof-of-concept-development-of-snow-liquid-water-content-profiler-using-cs650-reflectometers-at-caribou-me-usa
#1
Carlos L Pérez Díaz, Jonathan Muñoz, Tarendra Lakhankar, Reza Khanbilvardi, Peter Romanov
The quantity of liquid water in the snowpack defines its wetness. The temporal evolution of snow wetness's plays a significant role in wet-snow avalanche prediction, meltwater release, and water availability estimations and assessments within a river basin. However, it remains a difficult task and a demanding issue to measure the snowpack's liquid water content (LWC) and its temporal evolution with conventional in situ techniques. We propose an approach based on the use of time-domain reflectometry (TDR) and CS650 soil water content reflectometers to measure the snowpack's LWC and temperature profiles...
March 21, 2017: Sensors
https://www.readbyqxmd.com/read/28335252/stress-waves-and-characteristics-of-zigzag-and-armchair-silicene-nanoribbons
#2
Yu-Cheng Fan, Te-Hua Fang, Tao-Hsing Chen
The mechanical properties of silicene nanostructures subject to tensile loading were studied via a molecular dynamics (MD) simulation. The effects of temperature on Young's modulus and the fracture strain of silicene with armchair and zigzag types were examined. The maximum in-plane stress and the corresponding critical strain of the armchair and the zigzag silicene sheets at 300 K were 8.85 and 10.62, and 0.187 and 0.244 N/m, respectively. The in-plane stresses of the silicene sheet in the armchair direction at the temperatures of 300, 400, 500, and 600 K were 8...
June 24, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334643/dual-tail-approach-to-discovery-of-novel-carbonic-anhydrase-ix-inhibitors-by-simultaneously-matching-the-hydrophobic-and-hydrophilic-halves-of-the-active-site
#3
Zhuang Hou, Bin Lin, Yu Bao, Hai-Ning Yan, Miao Zhang, Xiao-Wei Chang, Xin-Xin Zhang, Zi-Jie Wang, Gao-Fei Wei, Mao-Sheng Cheng, Yang Liu, Chun Guo
Dual-tail approach was employed to design novel Carbonic Anhydrase (CA) IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site, which also contains a zinc ion as part of the catalytic center. The classic sulfanilamide moiety was used as the zinc binding group. An amino glucosamine fragment was chosen as the hydrophilic part and a cinnamamide fragment as the hydrophobic part in order to draw favorable interactions with the corresponding halves of the active site. In comparison with sulfanilamide which is largely devoid of the hydrophilic and hydrophobic interactions with the two halves of the active site, the compounds so designed and synthesized in this study showed 1000-fold improvement in binding affinity...
March 16, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28333685/a-spatially-resolved-network-spike-in-model-neuronal-cultures-reveals-nucleation-centers-circular-traveling-waves-and-drifting-spiral-waves
#4
A V Paraskevov, D K Zendrikov
We show that in model neuronal cultures, where the probability of interneuronal connection formation decreases exponentially with increasing distance between the neurons, there exists a small number of spatial nucleation centers of a network spike, from where the synchronous spiking activity starts propagating in the network typically in the form of circular traveling waves. The number of nucleation centers and their spatial locations are unique and unchanged for a given realization of neuronal network but are different for different networks...
March 23, 2017: Physical Biology
https://www.readbyqxmd.com/read/28333634/a-precision-analysis-of-camera-distortion-models
#5
Zhongwei Tang, Rafael Grompone von Gioi, Pascal Monasse, Jean-Michel Morel
This paper addresses the question of identifying the right camera direct or inverse distortion model permitting a high subpixel precision fit to real camera distortion. Five classic camera distortion models are reviewed and their precision compared for direct or inverse distortion. By definition, the three radially symmetric models can only model a distortion radially symmetric around some distortion center. They can be extended to deal with non-radially symmetric distortions by adding tangential distortion components, but still may be too simple for very accurate modeling of real cameras...
March 22, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28332661/geometrical-properties-of-the-manganese-iv-iron-iii-cofactor-of-chlamydia-trachomatis-ribonucleotide-reductase-unveiled-by-simulations-of-xas-spectra
#6
Eduardo M Sproviero
Using simulations of Mn/Fe K-edge X-ray absorption spectroscopy (XAS), combined with DFT-optimized structural models and direct comparisons with available experimental data, we determine geometrical and electronic properties of the Mn-Fe active site of Chlamydia trachomatis (Ct) of ribonucleotide reductase (RNR). In the post-edge XAS energy range, we use extended X-ray absorption fine structure (EXAFS) data, to acquire absorber-scatterer geometrical information around each absorber metal center. For this task, we apply a protocol that evaluates Debye-Waller factors in scattering paths instead of scattering shells to fit the experimental EXAFS...
March 23, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28328394/proposing-telecardiology-services-on-cloud-for-different-medical-institutions-a-model-of-reference
#7
Isabel De la Torre-Díez, Begoña Garcia-Zapirain, Miguel López-Coronado, Joel J P C Rodrigues
INTRODUCTION: For a cloud-based telecardiology solution to be established in any scenario, it is necessary to ensure optimum levels of security, as patient's data will not be in the same place from where access is gained. The main objective of this article is to present a secure, cloud-based solution for a telecardiology service in different scenarios: a hospital, a health center in a city, and a group of health centers in a rural area. METHODS: iCanCloud software is used to simulate the scenarios...
March 1, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28327517/combined-pre-distortion-and-censoring-for-bandwidth-efficient-and-energy-efficient-fusion-of-spectrum-sensing-information
#8
Guilherme Pedro Aquino, Dayan Adionel Guimarães, Luciano Leonel Mendes, Tales Cleber Pimenta
This paper describes a novel scheme for the fusion of spectrum sensing information in cooperative spectrum sensing for cognitive radio applications. The scheme combines a spectrum-efficient, pre-distortion-based fusion strategy with an energy-efficient censoring-based fusion strategy to achieve the combined effect of reduction in bandwidth and power consumption during the transmissions of the local decisions to the fusion center. Expressions for computing the key performance metrics of the spectrum sensing of the proposed scheme are derived and validated by means of computer simulations...
March 22, 2017: Sensors
https://www.readbyqxmd.com/read/28327195/does-rating-the-operation-videos-with-a-checklist-score-improve-the-effect-of-e-learning-for-bariatric-surgical-training-study-protocol-for-a-randomized-controlled-trial
#9
Javier Rodrigo De La Garza, Karl-Friedrich Kowalewski, Mirco Friedrich, Mona Wanda Schmidt, Thomas Bruckner, Hannes Götz Kenngott, Lars Fischer, Beat-Peter Müller-Stich, Felix Nickel
BACKGROUND: Laparoscopic training has become an important part of surgical education. Laparoscopic Roux-en-Y gastric bypass (RYGB) is the most common bariatric procedure performed. Surgeons must be well trained prior to operating on a patient. Multimodality training is vital for bariatric surgery. E-learning with videos is a standard approach for training. The present study investigates whether scoring the operation videos with performance checklists improves learning effects and transfer to a simulated operation...
March 21, 2017: Trials
https://www.readbyqxmd.com/read/28324976/meandered-conformai-antenna-for-ism-band-ingestible-capsule-communication-systems
#10
Md Shamsul Arefin, Jean-Michel Redoute, Mehmet Rasit Yuce
The wireless capsule has been used to measure physiological parameters in the gastrointestinal tract where communication from in-body to external receiver is necessary using a miniaturized antenna with high gain and onmidirectional radiation pattern. This paper presents a meandered conformal antenna with center frequency of 433 MHz for a wireless link between an in-body capsule system and an ex-body receiver system. The antenna is wrapped around the wireless capsule, which provides extra space for other circuits and sensors inside the capsule as well as allows it having larger dimensions compared to inner antennas...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324963/quantitative-assessment-of-arm-tremor-in-people-with-neurological-disorders
#11
Jeonghee Kim, Claire Parnell, Thomas Wichmann, Stephen P DeWeerth
Abnormal oscillatory movement (i.e. tremor) is usually evaluated with qualitative assessment by clinicians, and quantified with subjective scoring methods. These methods are often inaccurate. We utilized a quantitative and standardized task based on the Fitts' law to assess the performance of arm movement with tremor by controlling a gyration mouse on a computer. The experiment included the center-out tapping (COT) and rectangular track navigation (RTN) tasks. We report the results of a pilot study in which we collected the performance for healthy participants in whom tremor was simulated by imposing oscillatory movements to the arm with a vibration motor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323583/pilots-attention-distributions-between-chasing-a-moving-target-and-a-stationary-target
#12
Wen-Chin Li, Chung-San Yu, Graham Braithwaite, Matthew Greaves
INTRODUCTION: Attention plays a central role in cognitive processing; ineffective attention may induce accidents in flight operations. The objective of the current research was to examine military pilots' attention distributions between chasing a moving target and a stationary target. METHOD: In the current research, 37 mission-ready F-16 pilots participated. Subjects' eye movements were collected by a portable head-mounted eye-tracker during tactical training in a flight simulator...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28323251/plasmon-emitter-interaction-using-integrated-ring-grating-nanoantenna-structures
#13
Nancy Rahbany, Wei Geng, Renaud Bachelot, Christophe Couteau
Overcoming the diffraction limit to achieve high optical resolution is one of the main challenges in the fields of plasmonics, nanooptics and nanophotonics. In this work, we introduce novel plasmonic structures consisting of nanoantennas (nanoprisms, single bowtie nanoantennas and double bowtie nanoantennas) integrated in the center of ring diffraction gratings. Propagating surface plasmon polaritons (SPPs) are generated by the ring grating and coupled with localized surface plasmons (LSPs) at the nanoantennas exciting emitters placed in their gap...
March 21, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28323084/integration-of-in-hospital-cardiac-arrest-contextual-curriculum-into-a-basic-life-support-course-a-randomized-controlled-simulation-study
#14
Elizabeth A Hunt, Jordan M Duval-Arnould, Nnenna O Chime, Kareen Jones, Michael Rosen, Merona Hollingsworth, Deborah Aksamit, Marida Twilley, Cheryl Camacho, Daniel P Nogee, Julianna Jung, Kristen Nelson-McMillan, Nicole Shilkofski, Julianne S Perretta
OBJECTIVE: To compare resuscitation performance on simulated in-hospital cardiac arrests after traditional American Heart Association (AHA) Healthcare Provider Basic Life Support course (TradBLS) versus revised course including in-hospital skills (HospBLS). DESIGN: Prospective, randomized, controlled curriculum evaluation. SETTING: Johns Hopkins Medicine Simulation Center. SUBJECTS: One hundred twenty-two first year medical students divided into fifty-nine teams...
March 18, 2017: Resuscitation
https://www.readbyqxmd.com/read/28322631/priming-patient-safety-through-nursing-handoff-communication
#15
Patricia S Groves, Jacinda L Bunch, Ellen Cram, Amany Farag, Kirstin Manges, Yelena Perkhounkova, Jill Scott-Cawiezell
Understanding how safety culture mechanisms affect nursing safety-oriented behavior and thus patient outcomes is critical to developing hospital safety programs. Safety priming refers to communicating safety values intended to activate patient safety goals. Safety priming through nursing handoff communication was tested as a means by which cultural safety values may affect nursing practice. The mixed-methods pilot study setting was an academic medical center's high-fidelity simulation lab. Twenty nurses were randomized into intervention and control groups...
October 1, 2016: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28321677/identification-and-inhibitory-mechanism-of-angiotensin-i-converting-enzyme-inhibitory-peptides-derived-from-bovine-hemoglobin
#16
Ying Wang, Yiqun Jiang, Yongguang Yin, Jiyun Liu, Long Ding, Jingbo Liu, Ting Zhang
Angiotensin I-converting enzyme (ACE, EC.3.4.15.1) inhibitory peptide is an efficacious therapy for hypertension. In this study, four dipeptides, TY, FD, FL and FG, were identified from the desalted fraction of bovine hemoglobin hydrolysate, obtained by in vitro simulated gastrointestinal digestion, via liquid chromatography-tandem mass spectrometry (LC-MS/MS). The IC50 value of TY and FL are 96.43 ± 6.17 and 290.66 ± 57.92 μM, respectively. The result of molecular docking indicated that TY occupied the ACE subsite S1 and S1' with a lowest estimated binding energy of -9...
March 21, 2017: Protein Journal
https://www.readbyqxmd.com/read/28321219/computational-model-reveals-limited-correlation-between-germinal-center-b-cell-subclone-abundancy-and-affinity-implications-for-repertoire-sequencing
#17
Polina Reshetova, Barbera D C van Schaik, Paul L Klarenbeek, Marieke E Doorenspleet, Rebecca E E Esveldt, Paul-Peter Tak, Jeroen E J Guikema, Niek de Vries, Antoine H C van Kampen
Immunoglobulin repertoire sequencing has successfully been applied to identify expanded antigen-activated B-cell clones that play a role in the pathogenesis of immune disorders. One challenge is the selection of the Ag-specific B cells from the measured repertoire for downstream analyses. A general feature of an immune response is the expansion of specific clones resulting in a set of subclones with common ancestry varying in abundance and in the number of acquired somatic mutations. The expanded subclones are expected to have BCR affinities for the Ag higher than the affinities of the naive B cells in the background population...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28319990/a-decision-support-approach-for-provider-scheduling-in-a-patient-centered-medical-home
#18
Renata Konrad, Sarah Ficarra, Catherine Danko, Rachel Wallace, Cliona Archambeault
The patient-centered medical home (PCMH) has been proposed as a viable and medically effective model of primary care delivery. The fundamental principles of a PCMH address increased access and offer new ways to organize a practice. Creating provider schedules able to satisfy the operational and organizational constraints imposed by this type of delivery model is a challenging, complex, and time-consuming task.This article presents a two-step approach for scheduling providers and prospectively assessing the consequences of various schedules on patient throughput without experimenting on the real-world system...
January 2017: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/28319390/qualitative-behavior-of-the-low-frequency-vibrational-dynamics-of-microtubules-and-the-surrounding-water
#19
Jeremy M Moix, James E Parker, Ibtissam Echchgadda
The dynamics of the low-frequency vibrational modes of microtubules play a key role in many theoretical models regarding their biological function. We analyze these dynamics through large scale, classical molecular dynamics simulations of a microtubule composed of 42 tubulin heterodimers to provide insights into the qualitative nature of the vibrational energy absorption and dissipation mechanisms. The computed microtubule absorption spectra and vibrational density of states in the terahertz regime are presented, along with an analysis of the vibrational dephasing rates of the tubulin monomer center of mass dynamics, which are shown to be overdamped...
March 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28319122/can-a-simulation-based-training-program-impact-the-use-of-evidence-based-routine-practices-at-birth-results-of-a-hospital-based-cluster-randomized-trial-in-mexico
#20
Jimena Fritz, Dilys M Walker, Susanna Cohen, Gustavo Angeles, Hector Lamadrid-Figueroa
BACKGROUND: In Mexico, although the majority of births are attended in hospitals, reports have emerged of obstetric violence, use of unsafe practices, and failure to employ evidence-based practices (EBP). Recent attention has refocused global efforts towards provision of quality care that is both patient-centered and evidence-based. Scaling up of local interventions should rely on strong evidence of effectiveness. OBJECTIVE: To perform a secondary analysis to evaluate the impact of a simulation and team-training program (PRONTO) on the performance of EBP in normal births...
2017: PloS One
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